No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Adipocytokine signaling pathway 2 genes, 3 drugs (DrugBank) and 32 diseases shown |
1件: JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
2 | African trypanosomiasis 5 genes, 5 drugs (DrugBank) and 31 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
3 | AGE-RAGE signaling pathway in diabetic complications 4 genes, 5 drugs (DrugBank) and 32 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
4 | Allograft rejection 5 genes, 4 drugs (DrugBank) and 40 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
5 | Alzheimer disease 7 genes, 4 drugs (DrugBank) and 54 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
6 | Amoebiasis 7 genes, 6 drugs (DrugBank) and 38 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
7 | Amphetamine addiction 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
8 | Amyotrophic lateral sclerosis (ALS) 6 genes, 3 drugs (DrugBank) and 54 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
9 | Antifolate resistance 5 genes, 5 drugs (DrugBank) and 45 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
10 | Antigen processing and presentation 1 gene, 2 drugs (DrugBank) and 28 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
11 | Apoptosis 1 gene, 2 drugs (DrugBank) and 28 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
12 | Asthma 1 gene, 2 drugs (DrugBank) and 28 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
13 | Autoimmune thyroid disease 2 genes, 1 drug (DrugBank) and 24 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
14 | Axon guidance 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
15 | B cell receptor signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
16 | C-type lectin receptor signaling pathway 11 genes, 6 drugs (DrugBank) and 56 diseases shown |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
17 | Calcium signaling pathway 7 genes, 2 drugs (DrugBank) and 53 diseases shown |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
18 | cAMP signaling pathway 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: EDNRA |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
19 | Cell adhesion molecules (CAMs) 3 genes, 2 drugs (DrugBank) and 25 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: PDCD1 |
D10316 |
Nivolumab |
10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 |
20 | Cellular senescence 6 genes, 2 drugs (DrugBank) and 44 diseases shown |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
21 | cGMP-PKG signaling pathway 8 genes, 3 drugs (DrugBank) and 58 diseases shown |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
1件: OPRD1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
22 | Chagas disease (American trypanosomiasis) 5 genes, 5 drugs (DrugBank) and 31 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
23 | Chemokine signaling pathway 1 gene, 1 drug (DrugBank) and 8 diseases shown |
1件: JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
24 | Cholinergic synapse 1 gene, 1 drug (DrugBank) and 8 diseases shown |
1件: JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
25 | Cytokine-cytokine receptor interaction 12 genes, 11 drugs (DrugBank) and 56 diseases shown |
1件: CSF2RA |
D09930 |
Mavrilimumab |
2件: 41, 46 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL17A |
D09967 |
Secukinumab |
7件: 13, 37, 41, 46, 160, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
26 | Cytosolic DNA-sensing pathway 2 genes, 2 drugs (DrugBank) and 5 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
27 | Dilated cardiomyopathy (DCM) 1 gene, 2 drugs (DrugBank) and 28 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
28 | Dopaminergic synapse 3 genes, 1 drug (DrugBank) and 44 diseases shown |
3件: PPP3CA, PPP3CB, PPP3CC |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
29 | EGFR tyrosine kinase inhibitor resistance 4 genes, 5 drugs (DrugBank) and 23 diseases shown |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
30 | Endocrine and other factor-regulated calcium reabsorption 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: VDR |
D01518 |
Alfacalcidol |
6件: 41, 46, 49, 50, 96, 235 |
31 | Epstein-Barr virus infection 3 genes, 5 drugs (DrugBank) and 32 diseases shown |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
32 | Estrogen signaling pathway 1 gene, 1 drug (DrugBank) and 11 diseases shown |
1件: OPRM1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
33 | Fc epsilon RI signaling pathway 1 gene, 2 drugs (DrugBank) and 28 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
34 | Fluid shear stress and atherosclerosis 4 genes, 4 drugs (DrugBank) and 36 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
35 | Folate biosynthesis 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
36 | FoxO signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
37 | Glucagon signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
38 | Glutamatergic synapse 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
39 | Graft-versus-host disease 5 genes, 5 drugs (DrugBank) and 40 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
40 | Growth hormone synthesis, secretion and action 1 gene, 1 drug (DrugBank) and 8 diseases shown |
1件: JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
41 | Hematopoietic cell lineage 8 genes, 9 drugs (DrugBank) and 55 diseases shown |
1件: CSF2RA |
D09930 |
Mavrilimumab |
2件: 41, 46 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
42 | Hepatitis B 4 genes, 5 drugs (DrugBank) and 32 diseases shown |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
43 | Hepatitis C 2 genes, 4 drugs (DrugBank) and 32 diseases shown |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
44 | Herpes simplex virus 1 infection 7 genes, 7 drugs (DrugBank) and 34 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
45 | HIF-1 signaling pathway 2 genes, 3 drugs (DrugBank) and 17 diseases shown |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
46 | Human cytomegalovirus infection 11 genes, 10 drugs (DrugBank) and 68 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
47 | Human immunodeficiency virus 1 infection 6 genes, 3 drugs (DrugBank) and 54 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
48 | Human papillomavirus infection 2 genes, 4 drugs (DrugBank) and 32 diseases shown |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
49 | Human T-cell leukemia virus 1 infection 11 genes, 8 drugs (DrugBank) and 65 diseases shown |
1件: FDPS |
D00939 |
Alendronic acid |
7件: 19, 41, 46, 50, 271, 274, 299 |
D07119 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
50 | Hypertrophic cardiomyopathy (HCM) 2 genes, 3 drugs (DrugBank) and 28 diseases shown |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
51 | IL-17 signaling pathway 4 genes, 5 drugs (DrugBank) and 29 diseases shown |
1件: IL17A |
D09967 |
Secukinumab |
7件: 13, 37, 41, 46, 160, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
52 | Inflammatory bowel disease (IBD) 7 genes, 6 drugs (DrugBank) and 31 diseases shown |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL17A |
D09967 |
Secukinumab |
7件: 13, 37, 41, 46, 160, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
53 | Inflammatory mediator regulation of TRP channels 2 genes, 2 drugs (DrugBank) and 18 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
54 | Influenza A 8 genes, 8 drugs (DrugBank) and 36 diseases shown |
1件: FDPS |
D00939 |
Alendronic acid |
7件: 19, 41, 46, 50, 271, 274, 299 |
D07119 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
55 | Insulin resistance 2 genes, 3 drugs (DrugBank) and 28 diseases shown |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
56 | Intestinal immune network for IgA production 3 genes, 2 drugs (DrugBank) and 24 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
57 | JAK-STAT signaling pathway 9 genes, 8 drugs (DrugBank) and 46 diseases shown |
1件: CSF2RA |
D09930 |
Mavrilimumab |
2件: 41, 46 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
58 | Kaposi sarcoma-associated herpesvirus infection 9 genes, 5 drugs (DrugBank) and 55 diseases shown |
1件: CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
59 | Legionellosis 5 genes, 5 drugs (DrugBank) and 31 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
60 | Leishmaniasis 6 genes, 6 drugs (DrugBank) and 34 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
61 | Long-term potentiation 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
62 | Malaria 4 genes, 5 drugs (DrugBank) and 31 diseases shown |
1件: IL12A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
63 | MAPK signaling pathway 8 genes, 5 drugs (DrugBank) and 62 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
64 | Measles 5 genes, 5 drugs (DrugBank) and 19 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
65 | Melanogenesis 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
66 | Metabolic pathways 3 genes, 2 drugs (DrugBank) and 35 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
1件: FDPS |
D00939 |
Alendronic acid |
7件: 19, 41, 46, 50, 271, 274, 299 |
D07119 |
67 | Mineral absorption 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: VDR |
D01518 |
Alfacalcidol |
6件: 41, 46, 49, 50, 96, 235 |
68 | Morphine addiction 1 gene, 1 drug (DrugBank) and 11 diseases shown |
1件: OPRM1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
69 | mTOR signaling pathway 1 gene, 2 drugs (DrugBank) and 28 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
70 | Natural killer cell mediated cytotoxicity 6 genes, 3 drugs (DrugBank) and 54 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
71 | Necroptosis 4 genes, 5 drugs (DrugBank) and 32 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
72 | Neuroactive ligand-receptor interaction 6 genes, 7 drugs (DrugBank) and 65 diseases shown |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
1件: NR3C1 |
D00407 |
Methylprednisolone |
36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 |
D00751 |
D00979 |
D05000 |
D05001 |
D05002 |
D00472 |
Prednisolone |
38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
D00980 |
D00981 |
D00982 |
D01239 |
D01998 |
D02156 |
D03301 |
D00473 |
Prednisone |
44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
D08416 |
Prednisone acetate |
6件: 35, 40, 41, 49, 162, 224 |
D00385 |
Triamcinolone |
18件: 6, 10, 13, 35, 40, 41, 42, 43, 44, 45, 46, 56, 70, 90, 96, 97, 226, 298 |
D00983 |
D00984 |
D00985 |
D06216 |
3件: OPRD1, OPRK1, OPRM1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
73 | NF-kappa B signaling pathway 3 genes, 4 drugs (DrugBank) and 36 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
74 | NOD-like receptor signaling pathway 4 genes, 6 drugs (DrugBank) and 32 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
75 | Non-alcoholic fatty liver disease (NAFLD) 4 genes, 6 drugs (DrugBank) and 38 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
76 | One carbon pool by folate 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
77 | Oocyte meiosis 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
78 | Osteoclast differentiation 9 genes, 7 drugs (DrugBank) and 65 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
79 | Oxytocin signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
80 | Pancreatic cancer 1 gene, 2 drugs (DrugBank) and 11 diseases shown |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
81 | Parathyroid hormone synthesis, secretion and action 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: VDR |
D01518 |
Alfacalcidol |
6件: 41, 46, 49, 50, 96, 235 |
82 | Pathogenic Escherichia coli infection 4 genes, 5 drugs (DrugBank) and 36 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
83 | Pathways in cancer 11 genes, 9 drugs (DrugBank) and 50 diseases shown |
1件: CSF2RA |
D09930 |
Mavrilimumab |
2件: 41, 46 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
84 | PD-L1 expression and PD-1 checkpoint pathway in cancer 8 genes, 4 drugs (DrugBank) and 52 diseases shown |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
1件: PDCD1 |
D10316 |
Nivolumab |
10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
85 | Pertussis 6 genes, 5 drugs (DrugBank) and 31 diseases shown |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
86 | PI3K-Akt signaling pathway 5 genes, 6 drugs (DrugBank) and 42 diseases shown |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
87 | Prion diseases 2 genes, 2 drugs (DrugBank) and 5 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
88 | Prolactin signaling pathway 1 gene, 1 drug (DrugBank) and 8 diseases shown |
1件: JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
89 | Prostate cancer 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
90 | Proteoglycans in cancer 2 genes, 3 drugs (DrugBank) and 31 diseases shown |
1件: IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
91 | Relaxin signaling pathway 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
92 | Renin secretion 6 genes, 2 drugs (DrugBank) and 53 diseases shown |
1件: EDNRA |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
93 | Rheumatoid arthritis 7 genes, 7 drugs (DrugBank) and 40 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL17A |
D09967 |
Secukinumab |
7件: 13, 37, 41, 46, 160, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
94 | RIG-I-like receptor signaling pathway 3 genes, 3 drugs (DrugBank) and 31 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
95 | Salmonella infection 2 genes, 2 drugs (DrugBank) and 5 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
96 | Shigellosis 3 genes, 4 drugs (DrugBank) and 36 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
97 | Signaling pathways regulating pluripotency of stem cells 2 genes, 2 drugs (DrugBank) and 11 diseases shown |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
98 | Sphingolipid signaling pathway 2 genes, 3 drugs (DrugBank) and 33 diseases shown |
1件: OPRD1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
99 | Systemic lupus erythematosus 3 genes, 3 drugs (DrugBank) and 40 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
100 | T cell receptor signaling pathway 7 genes, 4 drugs (DrugBank) and 56 diseases shown |
1件: PDCD1 |
D10316 |
Nivolumab |
10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
101 | Terpenoid backbone biosynthesis 1 gene, 1 drug (DrugBank) and 7 diseases shown |
1件: FDPS |
D00939 |
Alendronic acid |
7件: 19, 41, 46, 50, 271, 274, 299 |
D07119 |
102 | TGF-beta signaling pathway 1 gene, 2 drugs (DrugBank) and 28 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
103 | Th1 and Th2 cell differentiation 9 genes, 4 drugs (DrugBank) and 53 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
104 | Th17 cell differentiation 13 genes, 10 drugs (DrugBank) and 64 diseases shown |
1件: IL17A |
D09967 |
Secukinumab |
7件: 13, 37, 41, 46, 160, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
105 | TNF signaling pathway 3 genes, 4 drugs (DrugBank) and 28 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
106 | Toll-like receptor signaling pathway 7 genes, 6 drugs (DrugBank) and 40 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
107 | Toxoplasmosis 5 genes, 5 drugs (DrugBank) and 34 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
108 | Transcriptional misregulation in cancer 3 genes, 3 drugs (DrugBank) and 32 diseases shown |
1件: CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
109 | Tuberculosis 14 genes, 9 drugs (DrugBank) and 60 diseases shown |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
1件: VDR |
D01518 |
Alfacalcidol |
6件: 41, 46, 49, 50, 96, 235 |
110 | Type I diabetes mellitus 6 genes, 5 drugs (DrugBank) and 40 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
111 | Type II diabetes mellitus 1 gene, 2 drugs (DrugBank) and 28 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
112 | Vascular smooth muscle contraction 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: EDNRA |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
113 | VEGF signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
114 | Viral carcinogenesis 1 gene, 2 drugs (DrugBank) and 11 diseases shown |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
115 | Viral myocarditis 2 genes, 1 drug (DrugBank) and 24 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
116 | Viral protein interaction with cytokine and cytokine receptor 3 genes, 5 drugs (DrugBank) and 38 diseases shown |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
117 | Wnt signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
118 | Yersinia infection 3 genes, 4 drugs (DrugBank) and 28 diseases shown |
1件: IL1B |
D09911 |
Gevokizumab |
4件: 41, 50, 56, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |