No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Adipocytokine signaling pathway 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
2 | African trypanosomiasis 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
3 | AGE-RAGE signaling pathway in diabetic complications 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
4 | Allograft rejection 2 genes, 3 drugs (DrugBank) and 24 diseases shown |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
5 | Alzheimer disease 6 genes, 2 drugs (DrugBank) and 52 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
6 | Amoebiasis 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
7 | Amphetamine addiction 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
8 | Amyotrophic lateral sclerosis (ALS) 6 genes, 2 drugs (DrugBank) and 52 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
9 | Antifolate resistance 3 genes, 2 drugs (DrugBank) and 41 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
10 | Antigen processing and presentation 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
11 | Apoptosis 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
12 | Asthma 2 genes, 3 drugs (DrugBank) and 24 diseases shown |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
13 | Autoimmune thyroid disease 1 gene, 2 drugs (DrugBank) and 4 diseases shown |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
14 | Axon guidance 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
15 | B cell receptor signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
16 | C-type lectin receptor signaling pathway 6 genes, 2 drugs (DrugBank) and 52 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
17 | Calcium signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
18 | Cellular senescence 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
19 | cGMP-PKG signaling pathway 6 genes, 2 drugs (DrugBank) and 50 diseases shown |
1件: OPRD1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
20 | Chagas disease (American trypanosomiasis) 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
21 | Cytokine-cytokine receptor interaction 4 genes, 5 drugs (DrugBank) and 42 diseases shown |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
1件: IL5RA |
D09874 |
Benralizumab |
2件: 44, 45 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
22 | Dilated cardiomyopathy (DCM) 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
23 | Dopaminergic synapse 3 genes, 1 drug (DrugBank) and 44 diseases shown |
3件: PPP3CA, PPP3CB, PPP3CC |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
24 | Drug metabolism - other enzymes 2 genes, 2 drugs (DrugBank) and 34 diseases shown |
2件: IMPDH1, IMPDH2 |
D00752 |
Mycophenolate mofetil |
32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
D05094 |
D05095 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
25 | Epstein-Barr virus infection 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
26 | Estrogen signaling pathway 1 gene, 1 drug (DrugBank) and 11 diseases shown |
1件: OPRM1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
27 | Fc epsilon RI signaling pathway 2 genes, 3 drugs (DrugBank) and 24 diseases shown |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
28 | Fluid shear stress and atherosclerosis 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
29 | Folate biosynthesis 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
30 | Glucagon signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
31 | Glutamatergic synapse 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
32 | Graft-versus-host disease 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
33 | Hematopoietic cell lineage 5 genes, 6 drugs (DrugBank) and 61 diseases shown |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
1件: IL5RA |
D09874 |
Benralizumab |
2件: 44, 45 |
1件: MS4A1 |
D02994 |
Rituximab |
42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
34 | Hepatitis B 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
35 | Hepatitis C 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
36 | Herpes simplex virus 1 infection 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
37 | Human cytomegalovirus infection 6 genes, 2 drugs (DrugBank) and 52 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
38 | Human immunodeficiency virus 1 infection 6 genes, 2 drugs (DrugBank) and 52 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
39 | Human papillomavirus infection 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
40 | Human T-cell leukemia virus 1 infection 6 genes, 2 drugs (DrugBank) and 52 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
41 | Hypertrophic cardiomyopathy (HCM) 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
42 | IL-17 signaling pathway 2 genes, 3 drugs (DrugBank) and 24 diseases shown |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
43 | Inflammatory bowel disease (IBD) 2 genes, 3 drugs (DrugBank) and 24 diseases shown |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
44 | Influenza A 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
45 | Insulin resistance 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
46 | Intestinal immune network for IgA production 1 gene, 2 drugs (DrugBank) and 4 diseases shown |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
47 | JAK-STAT signaling pathway 3 genes, 4 drugs (DrugBank) and 31 diseases shown |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
1件: IL5RA |
D09874 |
Benralizumab |
2件: 44, 45 |
48 | Kaposi sarcoma-associated herpesvirus infection 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
49 | Legionellosis 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
50 | Leishmaniasis 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
51 | Long-term potentiation 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
52 | Malaria 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
53 | MAPK signaling pathway 6 genes, 2 drugs (DrugBank) and 52 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
54 | Metabolic pathways 4 genes, 3 drugs (DrugBank) and 48 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
2件: IMPDH1, IMPDH2 |
D00752 |
Mycophenolate mofetil |
32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
D05094 |
D05095 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
55 | Morphine addiction 1 gene, 1 drug (DrugBank) and 11 diseases shown |
1件: OPRM1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
56 | mTOR signaling pathway 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
57 | Natural killer cell mediated cytotoxicity 6 genes, 2 drugs (DrugBank) and 52 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
58 | Necroptosis 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
59 | Neuroactive ligand-receptor interaction 4 genes, 5 drugs (DrugBank) and 61 diseases shown |
1件: NR3C1 |
D00407 |
Methylprednisolone |
36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 |
D00751 |
D00979 |
D05000 |
D05001 |
D05002 |
D00472 |
Prednisolone |
38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
D00980 |
D00981 |
D00982 |
D01239 |
D01998 |
D02156 |
D03301 |
D00473 |
Prednisone |
44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
D00385 |
Triamcinolone |
18件: 6, 10, 13, 35, 40, 41, 42, 43, 44, 45, 46, 56, 70, 90, 96, 97, 226, 298 |
D00983 |
D00984 |
D00985 |
D06216 |
3件: OPRD1, OPRK1, OPRM1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
60 | NF-kappa B signaling pathway 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
61 | NOD-like receptor signaling pathway 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
62 | Non-alcoholic fatty liver disease (NAFLD) 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
63 | One carbon pool by folate 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
64 | Oocyte meiosis 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
65 | Osteoclast differentiation 6 genes, 2 drugs (DrugBank) and 52 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
66 | Oxytocin signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
67 | Pathogenic Escherichia coli infection 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
68 | Pathways in cancer 3 genes, 4 drugs (DrugBank) and 31 diseases shown |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
1件: IL5RA |
D09874 |
Benralizumab |
2件: 44, 45 |
69 | PD-L1 expression and PD-1 checkpoint pathway in cancer 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
70 | Pertussis 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
71 | PI3K-Akt signaling pathway 1 gene, 1 drug (DrugBank) and 28 diseases shown |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
72 | Proteoglycans in cancer 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
73 | Purine metabolism 2 genes, 2 drugs (DrugBank) and 34 diseases shown |
2件: IMPDH1, IMPDH2 |
D00752 |
Mycophenolate mofetil |
32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
D05094 |
D05095 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
74 | Renin secretion 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
75 | Rheumatoid arthritis 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
76 | RIG-I-like receptor signaling pathway 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
77 | Shigellosis 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
78 | Sphingolipid signaling pathway 2 genes, 2 drugs (DrugBank) and 28 diseases shown |
1件: OPRD1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
79 | Systemic lupus erythematosus 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
80 | T cell receptor signaling pathway 7 genes, 4 drugs (DrugBank) and 53 diseases shown |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
81 | TGF-beta signaling pathway 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
82 | Th1 and Th2 cell differentiation 6 genes, 3 drugs (DrugBank) and 46 diseases shown |
1件: IL5 |
D04923 |
Mepolizumab |
4件: 44, 45, 98, 162 |
D08985 |
Reslizumab |
3件: 44, 45, 98 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
83 | Th17 cell differentiation 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
84 | TNF signaling pathway 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
85 | Toll-like receptor signaling pathway 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
86 | Toxoplasmosis 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
87 | Tuberculosis 6 genes, 2 drugs (DrugBank) and 52 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
88 | Type I diabetes mellitus 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
89 | Type II diabetes mellitus 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
90 | VEGF signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
91 | Viral protein interaction with cytokine and cytokine receptor 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
92 | Wnt signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
93 | Yersinia infection 1 gene, 1 drug (DrugBank) and 23 diseases shown |
1件: TNF |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |