No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Acute myeloid leukemia 3 genes, 4 drugs (DrugBank) and 43 diseases shown |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
2 | Adipocytokine signaling pathway 6 genes, 14 drugs (DrugBank) and 74 diseases shown |
1件: JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3 | Adrenergic signaling in cardiomyocytes 16 genes, 9 drugs (DrugBank) and 31 diseases shown |
5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
2件: AGTR1, AGTR2 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D02716 |
Pregabalin |
5件: 13, 36, 46, 70, 298 |
1件: SCN5A |
D01450 |
Bupivacaine |
7件: 46, 53, 70, 96, 168, 226, 298 |
D07552 |
D01287 |
Levobupivacaine |
1件: 46 |
D08116 |
D00358 |
Lidocaine |
10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
D04048 |
Ropivacaine |
3件: 36, 46, 70 |
D08490 |
4 | African trypanosomiasis 7 genes, 12 drugs (DrugBank) and 45 diseases shown |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
5 | AGE-RAGE signaling pathway in diabetic complications 8 genes, 16 drugs (DrugBank) and 56 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
6 | Alcoholism 7 genes, 3 drugs (DrugBank) and 12 diseases shown |
1件: ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
2件: ADORA2A, ADORA2B |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
7 | Aldosterone synthesis and secretion 7 genes, 5 drugs (DrugBank) and 30 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
1件: PDE2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
8 | Aldosterone-regulated sodium reabsorption 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
9 | Allograft rejection 7 genes, 12 drugs (DrugBank) and 46 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
D03222 |
Belatacept |
1件: 46 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
10 | Alzheimer disease 12 genes, 12 drugs (DrugBank) and 73 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
11 | Amoebiasis 10 genes, 14 drugs (DrugBank) and 48 diseases shown |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
12 | Amphetamine addiction 10 genes, 3 drugs (DrugBank) and 59 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
13 | AMPK signaling pathway 6 genes, 10 drugs (DrugBank) and 69 diseases shown |
1件: ADRA1A |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
D00893 |
Pravastatin |
9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 |
D08410 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
14 | Amyotrophic lateral sclerosis (ALS) 11 genes, 11 drugs (DrugBank) and 69 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
15 | Antifolate resistance 6 genes, 12 drugs (DrugBank) and 55 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
16 | Antigen processing and presentation 2 genes, 9 drugs (DrugBank) and 38 diseases shown |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
17 | Apelin signaling pathway 5 genes, 5 drugs (DrugBank) and 55 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
18 | Apoptosis 2 genes, 9 drugs (DrugBank) and 38 diseases shown |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
19 | Arachidonic acid metabolism 3 genes, 17 drugs (DrugBank) and 23 diseases shown |
3件: PTGES, PTGS1, PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
20 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) 5 genes, 2 drugs (DrugBank) and 9 diseases shown |
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D02716 |
Pregabalin |
5件: 13, 36, 46, 70, 298 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
21 | Asthma 2 genes, 8 drugs (DrugBank) and 38 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
22 | Autoimmune thyroid disease 3 genes, 3 drugs (DrugBank) and 28 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
D03222 |
Belatacept |
1件: 46 |
1件: IL10 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
23 | Autophagy - animal 3 genes, 2 drugs (DrugBank) and 46 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
24 | Autophagy - other 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
25 | Axon guidance 6 genes, 3 drugs (DrugBank) and 59 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
26 | B cell receptor signaling pathway 8 genes, 6 drugs (DrugBank) and 56 diseases shown |
1件: BTK |
D10893 |
Acalabrutinib |
1件: 46 |
D11478 |
Branebrutinib |
1件: 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
27 | Bile secretion 5 genes, 6 drugs (DrugBank) and 36 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
D00893 |
Pravastatin |
9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 |
D08410 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
28 | Breast cancer 6 genes, 8 drugs (DrugBank) and 47 diseases shown |
1件: ESR1 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
2件: ESR1, ESR2 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
D02217 |
Raloxifene |
1件: 46 |
D08465 |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PGR |
D00182 |
Norethisterone |
4件: 13, 46, 49, 299 |
D00953 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
29 | C-type lectin receptor signaling pathway 15 genes, 32 drugs (DrugBank) and 79 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
30 | Caffeine metabolism 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: XDH |
D00224 |
Allopurinol |
6件: 6, 46, 57, 66, 96, 97 |
31 | Calcium signaling pathway 25 genes, 14 drugs (DrugBank) and 73 diseases shown |
2件: ADORA2A, ADORA2B |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
2件: ADORA2A, PDE1B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
1件: CYSLTR1 |
D00529 |
Montelukast |
5件: 13, 46, 85, 98, 228 |
D08229 |
4件: GRIN1, GRIN2A, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: HRH1 |
D00364 |
Loratadine |
3件: 6, 13, 46 |
2件: HRH1, PTAFR |
D07407 |
Rupatadine |
1件: 46 |
1件: HRH2 |
D00318 |
Famotidine |
3件: 6, 46, 86 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGER3 |
D00419 |
Misoprostol |
2件: 46, 271 |
32 | cAMP signaling pathway 23 genes, 10 drugs (DrugBank) and 29 diseases shown |
2件: ADORA1, ADORA2A |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
2件: ADRB1, ADRB2 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PDE4A |
D00302 |
Dipyridamole |
5件: 46, 49, 51, 66, 224 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D08860 |
Apremilast |
5件: 46, 50, 56, 97, 271 |
2件: PTGER2, PTGER3 |
D00419 |
Misoprostol |
2件: 46, 271 |
33 | Carbohydrate digestion and absorption 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
34 | Cardiac muscle contraction 8 genes, 2 drugs (DrugBank) and 6 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D02716 |
Pregabalin |
5件: 13, 36, 46, 70, 298 |
35 | Cell adhesion molecules (CAMs) 5 genes, 5 drugs (DrugBank) and 31 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
D03222 |
Belatacept |
1件: 46 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: PDCD1 |
D10316 |
Nivolumab |
10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 |
36 | Cell cycle 1 gene, 1 drug (DrugBank) and 11 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
37 | Cellular senescence 9 genes, 6 drugs (DrugBank) and 74 diseases shown |
2件: IL1A, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
38 | Central carbon metabolism in cancer 3 genes, 3 drugs (DrugBank) and 41 diseases shown |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
39 | cGMP-PKG signaling pathway 26 genes, 11 drugs (DrugBank) and 75 diseases shown |
2件: ADORA1, ADORA3 |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
1件: OPRD1 |
D03783 |
Oxycodone |
7件: 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
1件: PDE5A |
D00302 |
Dipyridamole |
5件: 46, 49, 51, 66, 224 |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
40 | Chagas disease (American trypanosomiasis) 13 genes, 17 drugs (DrugBank) and 49 diseases shown |
1件: ACE |
D00621 |
Enalapril |
4件: 19, 46, 66, 113 |
D07892 |
D00362 |
Lisinopril |
5件: 46, 66, 67, 113, 222 |
D08131 |
D00421 |
Ramipril |
7件: 46, 49, 66, 67, 113, 218, 257 |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: CD3D, CD3E, CD3G |
D08959 |
Otelixizumab |
1件: 46 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
41 | Chemical carcinogenesis 1 gene, 17 drugs (DrugBank) and 23 diseases shown |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
42 | Chemokine signaling pathway 5 genes, 6 drugs (DrugBank) and 20 diseases shown |
1件: CCL2 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
1件: JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
2件: JAK2, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
43 | Choline metabolism in cancer 2 genes, 2 drugs (DrugBank) and 39 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
44 | Cholinergic synapse 2 genes, 4 drugs (DrugBank) and 21 diseases shown |
1件: ACHE |
D00670 |
Donepezil |
9件: 5, 6, 13, 46, 78, 124, 127, 156, 206 |
D07869 |
1件: JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
45 | Chronic myeloid leukemia 2 genes, 2 drugs (DrugBank) and 13 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
46 | Circadian entrainment 7 genes, 3 drugs (DrugBank) and 13 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
2件: MTNR1A, MTNR1B |
D08170 |
Melatonin |
8件: 6, 13, 46, 49, 90, 97, 144, 202 |
D02689 |
Ramelteon |
3件: 6, 8, 46 |
47 | Circadian rhythm 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
48 | Cocaine addiction 6 genes, 2 drugs (DrugBank) and 11 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
49 | Collecting duct acid secretion 2 genes, 2 drugs (DrugBank) and 16 diseases shown |
2件: ATP4A, ATP4B |
D01984 |
Esomeprazole |
6件: 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
50 | Colorectal cancer 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
51 | Complement and coagulation cascades 3 genes, 4 drugs (DrugBank) and 7 diseases shown |
1件: F10 |
D09710 |
Edoxaban |
2件: 46, 88 |
D07086 |
Rivaroxaban |
2件: 46, 49 |
1件: PLG |
D01136 |
Tranexamic acid |
5件: 46, 70, 215, 227, 288 |
1件: SERPINC1 |
D03674 |
Enoxaparin |
1件: 46 |
D07510 |
52 | Cortisol synthesis and secretion 2 genes, 3 drugs (DrugBank) and 28 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
53 | Cushing syndrome 2 genes, 3 drugs (DrugBank) and 28 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
54 | Cytokine-cytokine receptor interaction 27 genes, 30 drugs (DrugBank) and 78 diseases shown |
6件: CCL2, IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
1件: CSF2RA |
D09930 |
Mavrilimumab |
2件: 41, 46 |
D05712 |
Regramostim |
4件: 11, 46, 51, 229 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EPOR |
D03231 |
Erythropoietin |
9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL17A |
D09967 |
Secukinumab |
7件: 13, 37, 41, 46, 160, 269, 271 |
2件: IL17A, IL17F |
D11550 |
Bimekizumab |
3件: 46, 97, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: LTA |
D10187 |
Pateclizumab |
1件: 46 |
2件: LTA, TNF |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
1件: LTB |
D08866 |
Baminercept |
4件: 13, 46, 53, 97 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
2件: TNFSF13, TNFSF13B |
D09704 |
Atacicept |
4件: 13, 46, 49, 66 |
1件: TNFSF13B |
D03068 |
Belimumab |
8件: 11, 43, 44, 46, 49, 51, 53, 222 |
D10083 |
Tabalumab |
2件: 46, 49 |
55 | Cytosolic DNA-sensing pathway 3 genes, 4 drugs (DrugBank) and 20 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
56 | Dilated cardiomyopathy (DCM) 7 genes, 11 drugs (DrugBank) and 48 diseases shown |
1件: ADRB1 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D02716 |
Pregabalin |
5件: 13, 36, 46, 70, 298 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
57 | DNA replication 2 genes, 1 drug (DrugBank) and 9 diseases shown |
2件: POLA1, POLA2 |
D03546 |
Clofarabine |
9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 |
58 | Dopaminergic synapse 6 genes, 7 drugs (DrugBank) and 65 diseases shown |
2件: GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
3件: PPP3CA, PPP3CB, PPP3CC |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: SCN1A |
D01450 |
Bupivacaine |
7件: 46, 53, 70, 96, 168, 226, 298 |
D07552 |
D01287 |
Levobupivacaine |
1件: 46 |
D08116 |
D00358 |
Lidocaine |
10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
D04048 |
Ropivacaine |
3件: 36, 46, 70 |
D08490 |
59 | Drug metabolism - other enzymes 4 genes, 4 drugs (DrugBank) and 29 diseases shown |
2件: IMPDH1, IMPDH2 |
D01392 |
Mizoribine |
8件: 46, 49, 51, 53, 66, 94, 222, 224 |
1件: RRM1 |
D03546 |
Clofarabine |
9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
1件: XDH |
D00224 |
Allopurinol |
6件: 6, 46, 57, 66, 96, 97 |
60 | ECM-receptor interaction 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
61 | EGFR tyrosine kinase inhibitor resistance 6 genes, 12 drugs (DrugBank) and 57 diseases shown |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
62 | Endocrine and other factor-regulated calcium reabsorption 7 genes, 10 drugs (DrugBank) and 29 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
1件: ESR1 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
D02217 |
Raloxifene |
1件: 46 |
D08465 |
1件: PTH1R |
D06078 |
Teriparatide |
7件: 46, 65, 68, 70, 71, 235, 274 |
1件: VDR |
D01518 |
Alfacalcidol |
6件: 41, 46, 49, 50, 96, 235 |
D00129 |
Calcitriol |
8件: 37, 46, 49, 66, 96, 158, 235, 326 |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D07578 |
Eldecalcitol |
1件: 46 |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
63 | Endocrine resistance 3 genes, 4 drugs (DrugBank) and 38 diseases shown |
1件: ESR1 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
2件: ESR1, ESR2 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
D02217 |
Raloxifene |
1件: 46 |
D08465 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
64 | Endocytosis 2 genes, 2 drugs (DrugBank) and 12 diseases shown |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
65 | Epithelial cell signaling in Helicobacter pylori infection 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
66 | Epstein-Barr virus infection 14 genes, 22 drugs (DrugBank) and 46 diseases shown |
1件: BTK |
D10893 |
Acalabrutinib |
1件: 46 |
D11478 |
Branebrutinib |
1件: 46 |
3件: CD3D, CD3E, CD3G |
D08959 |
Otelixizumab |
1件: 46 |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
3件: JAK1, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
67 | ErbB signaling pathway 2 genes, 2 drugs (DrugBank) and 39 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
68 | Estrogen signaling pathway 4 genes, 9 drugs (DrugBank) and 15 diseases shown |
1件: ESR1 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
2件: ESR1, ESR2 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
D02217 |
Raloxifene |
1件: 46 |
D08465 |
1件: OPRM1 |
D00836 |
Buprenorphine |
2件: 46, 70 |
D07132 |
D00320 |
Fentanyl |
5件: 46, 70, 85, 215, 231 |
D01399 |
D00842 |
Morphine |
4件: 36, 46, 70, 86 |
D02271 |
D08233 |
D03783 |
Oxycodone |
7件: 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
D01355 |
Tramadol |
5件: 46, 70, 78, 226, 271 |
D08623 |
1件: PGR |
D00182 |
Norethisterone |
4件: 13, 46, 49, 299 |
D00953 |
69 | Fc epsilon RI signaling pathway 3 genes, 11 drugs (DrugBank) and 40 diseases shown |
1件: BTK |
D10893 |
Acalabrutinib |
1件: 46 |
D11478 |
Branebrutinib |
1件: 46 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
70 | Fc gamma R-mediated phagocytosis 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
71 | Fluid shear stress and atherosclerosis 12 genes, 15 drugs (DrugBank) and 60 diseases shown |
4件: CCL2, IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: KEAP1 |
D03846 |
Dimethyl fumarate |
5件: 13, 46, 49, 51, 86 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: NQO1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
72 | Focal adhesion 2 genes, 2 drugs (DrugBank) and 15 diseases shown |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
73 | Folate biosynthesis 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
74 | FoxO signaling pathway 4 genes, 3 drugs (DrugBank) and 27 diseases shown |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
75 | GABAergic synapse 16 genes, 4 drugs (DrugBank) and 17 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00293 |
Diazepam |
3件: 46, 155, 298 |
D02624 |
Eszopiclone |
3件: 6, 13, 46 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
76 | Gap junction 11 genes, 3 drugs (DrugBank) and 17 diseases shown |
1件: ADRB1 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 |
D00491 |
Paclitaxel |
2件: 46, 85 |
D05333 |
77 | Gastric acid secretion 7 genes, 4 drugs (DrugBank) and 16 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
2件: ATP4A, ATP4B |
D01984 |
Esomeprazole |
6件: 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
1件: HRH2 |
D00318 |
Famotidine |
3件: 6, 46, 86 |
78 | Gastric cancer 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
79 | Glioma 2 genes, 2 drugs (DrugBank) and 39 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
80 | Glucagon signaling pathway 8 genes, 4 drugs (DrugBank) and 65 diseases shown |
1件: PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
81 | Glutamatergic synapse 10 genes, 3 drugs (DrugBank) and 59 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
82 | Glutathione metabolism 1 gene, 2 drugs (DrugBank) and 21 diseases shown |
1件: RRM1 |
D03546 |
Clofarabine |
9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
83 | Glycerophospholipid metabolism 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: ACHE |
D00670 |
Donepezil |
9件: 5, 6, 13, 46, 78, 124, 127, 156, 206 |
D07869 |
84 | GnRH secretion 1 gene, 2 drugs (DrugBank) and 5 diseases shown |
1件: ESR2 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
D02217 |
Raloxifene |
1件: 46 |
D08465 |
85 | GnRH signaling pathway 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: GNRHR |
D01685 |
Cetrorelix |
1件: 46 |
D07665 |
86 | Graft-versus-host disease 7 genes, 13 drugs (DrugBank) and 50 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
D03222 |
Belatacept |
1件: 46 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
87 | Growth hormone synthesis, secretion and action 3 genes, 5 drugs (DrugBank) and 58 diseases shown |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
1件: JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
88 | Hematopoietic cell lineage 16 genes, 25 drugs (DrugBank) and 82 diseases shown |
3件: CD3D, CD3E, CD3G |
D08959 |
Otelixizumab |
1件: 46 |
1件: CSF2RA |
D09930 |
Mavrilimumab |
2件: 41, 46 |
D05712 |
Regramostim |
4件: 11, 46, 51, 229 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EPOR |
D03231 |
Erythropoietin |
9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
1件: MS4A1 |
D05218 |
Ocrelizumab |
3件: 13, 46, 49 |
D09314 |
Ofatumumab |
3件: 13, 35, 46 |
D02994 |
Rituximab |
42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 |
D09031 |
Veltuzumab |
1件: 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
89 | Hepatitis B 8 genes, 17 drugs (DrugBank) and 42 diseases shown |
1件: IFNAR1 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
3件: JAK1, JAK2, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
90 | Hepatitis C 7 genes, 17 drugs (DrugBank) and 42 diseases shown |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10653 |
Peficitinib |
1件: 46 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
91 | Hepatocellular carcinoma 3 genes, 3 drugs (DrugBank) and 40 diseases shown |
1件: KEAP1 |
D03846 |
Dimethyl fumarate |
5件: 13, 46, 49, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NQO1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
92 | Herpes simplex virus 1 infection 16 genes, 23 drugs (DrugBank) and 69 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: LTA |
D10187 |
Pateclizumab |
1件: 46 |
2件: LTA, TNF |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
93 | HIF-1 signaling pathway 5 genes, 7 drugs (DrugBank) and 50 diseases shown |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
94 | Human cytomegalovirus infection 20 genes, 43 drugs (DrugBank) and 94 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
3件: PTGER2, PTGER3, PTGER4 |
D00419 |
Misoprostol |
2件: 46, 271 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
95 | Human immunodeficiency virus 1 infection 12 genes, 14 drugs (DrugBank) and 78 diseases shown |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
3件: CD3D, CD3E, CD3G |
D08959 |
Otelixizumab |
1件: 46 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
96 | Human papillomavirus infection 10 genes, 36 drugs (DrugBank) and 75 diseases shown |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10653 |
Peficitinib |
1件: 46 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PTGER4 |
D00419 |
Misoprostol |
2件: 46, 271 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
97 | Human T-cell leukemia virus 1 infection 18 genes, 26 drugs (DrugBank) and 73 diseases shown |
3件: CD3D, CD3E, CD3G |
D08959 |
Otelixizumab |
1件: 46 |
1件: FDPS |
D00939 |
Alendronic acid |
7件: 19, 41, 46, 50, 271, 274, 299 |
D07119 |
D08056 |
Ibandronate |
2件: 46, 49 |
D00942 |
Risedronic acid |
7件: 46, 66, 93, 95, 96, 113, 274 |
D03234 |
D08484 |
D01968 |
Zoledronic acid |
11件: 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: LTA |
D10187 |
Pateclizumab |
1件: 46 |
2件: LTA, TNF |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
98 | Huntington disease 3 genes, 3 drugs (DrugBank) and 22 diseases shown |
2件: GRIN1, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
99 | Hypertrophic cardiomyopathy (HCM) 10 genes, 15 drugs (DrugBank) and 59 diseases shown |
1件: ACE |
D00621 |
Enalapril |
4件: 19, 46, 66, 113 |
D07892 |
D00362 |
Lisinopril |
5件: 46, 66, 67, 113, 222 |
D08131 |
D00421 |
Ramipril |
7件: 46, 49, 66, 67, 113, 218, 257 |
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D02716 |
Pregabalin |
5件: 13, 36, 46, 70, 298 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
100 | IL-17 signaling pathway 9 genes, 31 drugs (DrugBank) and 57 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
1件: IL17A |
D09967 |
Secukinumab |
7件: 13, 37, 41, 46, 160, 269, 271 |
2件: IL17A, IL17F |
D11550 |
Bimekizumab |
3件: 46, 97, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
101 | Inflammatory bowel disease (IBD) 12 genes, 15 drugs (DrugBank) and 45 diseases shown |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL17A |
D09967 |
Secukinumab |
7件: 13, 37, 41, 46, 160, 269, 271 |
2件: IL17A, IL17F |
D11550 |
Bimekizumab |
3件: 46, 97, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
102 | Inflammatory mediator regulation of TRP channels 5 genes, 6 drugs (DrugBank) and 29 diseases shown |
1件: HRH1 |
D00364 |
Loratadine |
3件: 6, 13, 46 |
D07407 |
Rupatadine |
1件: 46 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
2件: PTGER2, PTGER4 |
D00419 |
Misoprostol |
2件: 46, 271 |
103 | Influenza A 16 genes, 25 drugs (DrugBank) and 56 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: FDPS |
D00939 |
Alendronic acid |
7件: 19, 41, 46, 50, 271, 274, 299 |
D07119 |
D08056 |
Ibandronate |
2件: 46, 49 |
D00942 |
Risedronic acid |
7件: 46, 66, 93, 95, 96, 113, 274 |
D03234 |
D08484 |
D01968 |
Zoledronic acid |
11件: 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PLG |
D01136 |
Tranexamic acid |
5件: 46, 70, 215, 227, 288 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
104 | Insulin resistance 6 genes, 12 drugs (DrugBank) and 71 diseases shown |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
105 | Insulin secretion 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
106 | Insulin signaling pathway 4 genes, 3 drugs (DrugBank) and 48 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
107 | Intestinal immune network for IgA production 7 genes, 8 drugs (DrugBank) and 33 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
D03222 |
Belatacept |
1件: 46 |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
2件: TNFSF13, TNFSF13B |
D09704 |
Atacicept |
4件: 13, 46, 49, 66 |
1件: TNFSF13B |
D03068 |
Belimumab |
8件: 11, 43, 44, 46, 49, 51, 53, 222 |
D10083 |
Tabalumab |
2件: 46, 49 |
108 | JAK-STAT signaling pathway 19 genes, 20 drugs (DrugBank) and 86 diseases shown |
1件: CSF2RA |
D09930 |
Mavrilimumab |
2件: 41, 46 |
D05712 |
Regramostim |
4件: 11, 46, 51, 229 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EPOR |
D03231 |
Erythropoietin |
9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
3件: JAK1, JAK2, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
109 | Kaposi sarcoma-associated herpesvirus infection 17 genes, 34 drugs (DrugBank) and 87 diseases shown |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
1件: CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
D03222 |
Belatacept |
1件: 46 |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
110 | Legionellosis 6 genes, 12 drugs (DrugBank) and 45 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
111 | Leishmaniasis 12 genes, 36 drugs (DrugBank) and 62 diseases shown |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
4件: IL10, IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
112 | Leukocyte transendothelial migration 2 genes, 2 drugs (DrugBank) and 12 diseases shown |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
113 | Long-term potentiation 10 genes, 3 drugs (DrugBank) and 59 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
114 | Longevity regulating pathway 5 genes, 5 drugs (DrugBank) and 53 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
115 | Longevity regulating pathway - multiple species 3 genes, 2 drugs (DrugBank) and 46 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
116 | Malaria 8 genes, 13 drugs (DrugBank) and 47 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
1件: IL12A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
117 | MAPK signaling pathway 16 genes, 16 drugs (DrugBank) and 74 diseases shown |
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D02716 |
Pregabalin |
5件: 13, 36, 46, 70, 298 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
118 | Measles 14 genes, 13 drugs (DrugBank) and 31 diseases shown |
3件: CD3D, CD3E, CD3G |
D08959 |
Otelixizumab |
1件: 46 |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
3件: JAK1, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
119 | Melanogenesis 1 gene, 2 drugs (DrugBank) and 15 diseases shown |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
120 | Melanoma 1 gene, 1 drug (DrugBank) and 11 diseases shown |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
121 | Metabolic pathways 25 genes, 39 drugs (DrugBank) and 88 diseases shown |
2件: ATP4A, ATP4B |
D01984 |
Esomeprazole |
6件: 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
1件: DHODH |
D00749 |
Leflunomide |
10件: 11, 40, 46, 49, 53, 66, 162, 224, 271, 300 |
1件: FDPS |
D00939 |
Alendronic acid |
7件: 19, 41, 46, 50, 271, 274, 299 |
D07119 |
D08056 |
Ibandronate |
2件: 46, 49 |
D00942 |
Risedronic acid |
7件: 46, 66, 93, 95, 96, 113, 274 |
D03234 |
D08484 |
D01968 |
Zoledronic acid |
11件: 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
D00893 |
Pravastatin |
9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 |
D08410 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
2件: IMPDH1, IMPDH2 |
D01392 |
Mizoribine |
8件: 46, 49, 51, 53, 66, 94, 222, 224 |
2件: NQO1, VKORC1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D08860 |
Apremilast |
5件: 46, 50, 56, 97, 271 |
2件: PDE4A, PDE5A |
D00302 |
Dipyridamole |
5件: 46, 49, 51, 66, 224 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
3件: PTGES, PTGS1, PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
1件: RRM1 |
D03546 |
Clofarabine |
9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
1件: XDH |
D00224 |
Allopurinol |
6件: 6, 46, 57, 66, 96, 97 |
122 | MicroRNAs in cancer 5 genes, 20 drugs (DrugBank) and 50 diseases shown |
2件: ABL1, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
123 | Mineral absorption 5 genes, 6 drugs (DrugBank) and 24 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
1件: VDR |
D01518 |
Alfacalcidol |
6件: 41, 46, 49, 50, 96, 235 |
D00129 |
Calcitriol |
8件: 37, 46, 49, 66, 96, 158, 235, 326 |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D07578 |
Eldecalcitol |
1件: 46 |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
124 | Morphine addiction 26 genes, 13 drugs (DrugBank) and 33 diseases shown |
1件: ADORA1 |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00293 |
Diazepam |
3件: 46, 155, 298 |
D02624 |
Eszopiclone |
3件: 6, 13, 46 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
1件: OPRM1 |
D00836 |
Buprenorphine |
2件: 46, 70 |
D07132 |
D00320 |
Fentanyl |
5件: 46, 70, 85, 215, 231 |
D01399 |
D00842 |
Morphine |
4件: 36, 46, 70, 86 |
D02271 |
D08233 |
D03783 |
Oxycodone |
7件: 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
D01355 |
Tramadol |
5件: 46, 70, 78, 226, 271 |
D08623 |
1件: PDE4A |
D00302 |
Dipyridamole |
5件: 46, 49, 51, 66, 224 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D08860 |
Apremilast |
5件: 46, 50, 56, 97, 271 |
125 | mTOR signaling pathway 4 genes, 10 drugs (DrugBank) and 71 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
126 | Natural killer cell mediated cytotoxicity 11 genes, 14 drugs (DrugBank) and 65 diseases shown |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
127 | Necroptosis 10 genes, 17 drugs (DrugBank) and 46 diseases shown |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
3件: JAK1, JAK2, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
128 | Neuroactive ligand-receptor interaction 56 genes, 35 drugs (DrugBank) and 100 diseases shown |
2件: ADORA1, ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
4件: ADORA1, ADORA2A, ADORA2B, ADORA3 |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
2件: AGTR1, AGTR2 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
2件: CNR1, CNR2 |
D10915 |
Cannabidiol |
14件: 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
D00306 |
Dronabinol |
5件: 2, 13, 46, 271, 298 |
1件: CYSLTR1 |
D00529 |
Montelukast |
5件: 13, 46, 85, 98, 228 |
D08229 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00293 |
Diazepam |
3件: 46, 155, 298 |
D02624 |
Eszopiclone |
3件: 6, 13, 46 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
1件: GNRHR |
D01685 |
Cetrorelix |
1件: 46 |
D07665 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: HRH1 |
D00364 |
Loratadine |
3件: 6, 13, 46 |
2件: HRH1, PTAFR |
D07407 |
Rupatadine |
1件: 46 |
1件: HRH2 |
D00318 |
Famotidine |
3件: 6, 46, 86 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
2件: MTNR1A, MTNR1B |
D08170 |
Melatonin |
8件: 6, 13, 46, 49, 90, 97, 144, 202 |
D02689 |
Ramelteon |
3件: 6, 8, 46 |
1件: NR3C1 |
D00244 |
Betamethasone |
6件: 2, 46, 65, 90, 96, 235 |
D00972 |
D01357 |
D01402 |
D01637 |
D02032 |
D02286 |
D00292 |
Dexamethasone |
20件: 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299 |
D00975 |
D01510 |
D01615 |
D01632 |
D01948 |
D02174 |
D02591 |
D02592 |
D00407 |
Methylprednisolone |
36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 |
D00751 |
D00979 |
D05000 |
D05001 |
D05002 |
D00472 |
Prednisolone |
38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
D00980 |
D00981 |
D00982 |
D01239 |
D01998 |
D02156 |
D03301 |
D00473 |
Prednisone |
44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
D00385 |
Triamcinolone |
18件: 6, 10, 13, 35, 40, 41, 42, 43, 44, 45, 46, 56, 70, 90, 96, 97, 226, 298 |
D00983 |
D00984 |
D00985 |
D06216 |
3件: OPRD1, OPRK1, OPRM1 |
D03783 |
Oxycodone |
7件: 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
2件: OPRK1, OPRM1 |
D00836 |
Buprenorphine |
2件: 46, 70 |
D07132 |
1件: OPRM1 |
D00320 |
Fentanyl |
5件: 46, 70, 85, 215, 231 |
D01399 |
D00842 |
Morphine |
4件: 36, 46, 70, 86 |
D02271 |
D08233 |
D01355 |
Tramadol |
5件: 46, 70, 78, 226, 271 |
D08623 |
1件: PLG |
D01136 |
Tranexamic acid |
5件: 46, 70, 215, 227, 288 |
3件: PTGER2, PTGER3, PTGER4 |
D00419 |
Misoprostol |
2件: 46, 271 |
1件: PTH1R |
D06078 |
Teriparatide |
7件: 46, 65, 68, 70, 71, 235, 274 |
129 | Neurotrophin signaling pathway 2 genes, 2 drugs (DrugBank) and 13 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
130 | NF-kappa B signaling pathway 11 genes, 37 drugs (DrugBank) and 63 diseases shown |
1件: BTK |
D10893 |
Acalabrutinib |
1件: 46 |
D11478 |
Branebrutinib |
1件: 46 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: LTA |
D10187 |
Pateclizumab |
1件: 46 |
2件: LTA, TNF |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
1件: LTB |
D08866 |
Baminercept |
4件: 13, 46, 53, 97 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
1件: TNFSF13B |
D09704 |
Atacicept |
4件: 13, 46, 49, 66 |
D03068 |
Belimumab |
8件: 11, 43, 44, 46, 49, 51, 53, 222 |
D10083 |
Tabalumab |
2件: 46, 49 |
131 | Nicotine addiction 21 genes, 5 drugs (DrugBank) and 20 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00293 |
Diazepam |
3件: 46, 155, 298 |
D02624 |
Eszopiclone |
3件: 6, 13, 46 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
132 | NOD-like receptor signaling pathway 9 genes, 18 drugs (DrugBank) and 46 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10653 |
Peficitinib |
1件: 46 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
133 | Non-alcoholic fatty liver disease (NAFLD) 8 genes, 14 drugs (DrugBank) and 60 diseases shown |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
134 | Non-small cell lung cancer 1 gene, 2 drugs (DrugBank) and 9 diseases shown |
1件: JAK3 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
135 | Olfactory transduction 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: PDE1B, PDE2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
136 | One carbon pool by folate 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
137 | Oocyte meiosis 6 genes, 3 drugs (DrugBank) and 55 diseases shown |
1件: PGR |
D00182 |
Norethisterone |
4件: 13, 46, 49, 299 |
D00953 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
138 | Osteoclast differentiation 19 genes, 27 drugs (DrugBank) and 78 diseases shown |
1件: BTK |
D10893 |
Acalabrutinib |
1件: 46 |
D11478 |
Branebrutinib |
1件: 46 |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10653 |
Peficitinib |
1件: 46 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
139 | Ovarian steroidogenesis 1 gene, 17 drugs (DrugBank) and 23 diseases shown |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
140 | Oxidative phosphorylation 2 genes, 2 drugs (DrugBank) and 16 diseases shown |
2件: ATP4A, ATP4B |
D01984 |
Esomeprazole |
6件: 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
141 | Oxytocin signaling pathway 12 genes, 21 drugs (DrugBank) and 76 diseases shown |
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D02716 |
Pregabalin |
5件: 13, 36, 46, 70, 298 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
142 | Pancreatic cancer 3 genes, 8 drugs (DrugBank) and 47 diseases shown |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
143 | Pancreatic secretion 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
144 | Parathyroid hormone synthesis, secretion and action 7 genes, 10 drugs (DrugBank) and 35 diseases shown |
1件: PDE4A |
D00302 |
Dipyridamole |
5件: 46, 49, 51, 66, 224 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D08860 |
Apremilast |
5件: 46, 50, 56, 97, 271 |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
1件: PTH1R |
D06078 |
Teriparatide |
7件: 46, 65, 68, 70, 71, 235, 274 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
1件: VDR |
D01518 |
Alfacalcidol |
6件: 41, 46, 49, 50, 96, 235 |
D00129 |
Calcitriol |
8件: 37, 46, 49, 66, 96, 158, 235, 326 |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D07578 |
Eldecalcitol |
1件: 46 |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
145 | Parkinson disease 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: ADORA2A |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
146 | Pathogenic Escherichia coli infection 15 genes, 14 drugs (DrugBank) and 49 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 |
D00491 |
Paclitaxel |
2件: 46, 85 |
D05333 |
147 | Pathways in cancer 29 genes, 48 drugs (DrugBank) and 93 diseases shown |
3件: ABL1, KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
1件: CSF2RA |
D09930 |
Mavrilimumab |
2件: 41, 46 |
D05712 |
Regramostim |
4件: 11, 46, 51, 229 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EPOR |
D03231 |
Erythropoietin |
9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 |
1件: ESR1 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
2件: ESR1, ESR2 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
D02217 |
Raloxifene |
1件: 46 |
D08465 |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
3件: JAK1, JAK2, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: KEAP1 |
D03846 |
Dimethyl fumarate |
5件: 13, 46, 49, 51, 86 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: NQO1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
3件: PTGER2, PTGER3, PTGER4 |
D00419 |
Misoprostol |
2件: 46, 271 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
148 | PD-L1 expression and PD-1 checkpoint pathway in cancer 14 genes, 13 drugs (DrugBank) and 78 diseases shown |
3件: CD3D, CD3E, CD3G |
D08959 |
Otelixizumab |
1件: 46 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PDCD1 |
D10316 |
Nivolumab |
10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
149 | Peroxisome 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: XDH |
D00224 |
Allopurinol |
6件: 6, 46, 57, 66, 96, 97 |
150 | Pertussis 9 genes, 12 drugs (DrugBank) and 45 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
151 | Phagosome 9 genes, 1 drug (DrugBank) and 2 diseases shown |
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 |
D00491 |
Paclitaxel |
2件: 46, 85 |
D05333 |
152 | Phospholipase D signaling pathway 5 genes, 6 drugs (DrugBank) and 51 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
153 | PI3K-Akt signaling pathway 18 genes, 21 drugs (DrugBank) and 87 diseases shown |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EPOR |
D03231 |
Erythropoietin |
9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
3件: JAK1, JAK2, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
154 | Platelet activation 4 genes, 13 drugs (DrugBank) and 20 diseases shown |
1件: BTK |
D10893 |
Acalabrutinib |
1件: 46 |
D11478 |
Branebrutinib |
1件: 46 |
1件: P2RY12 |
D09017 |
Ticagrelor |
1件: 46 |
1件: PTGS1 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
155 | PPAR signaling pathway 1 gene, 2 drugs (DrugBank) and 20 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
156 | Primary immunodeficiency 4 genes, 5 drugs (DrugBank) and 9 diseases shown |
1件: BTK |
D10893 |
Acalabrutinib |
1件: 46 |
D11478 |
Branebrutinib |
1件: 46 |
2件: CD3D, CD3E |
D08959 |
Otelixizumab |
1件: 46 |
1件: JAK3 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
157 | Prion diseases 3 genes, 3 drugs (DrugBank) and 18 diseases shown |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
158 | Progesterone-mediated oocyte maturation 2 genes, 2 drugs (DrugBank) and 9 diseases shown |
1件: PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
1件: PGR |
D00182 |
Norethisterone |
4件: 13, 46, 49, 299 |
D00953 |
159 | Prolactin signaling pathway 5 genes, 8 drugs (DrugBank) and 19 diseases shown |
1件: ESR1 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
2件: ESR1, ESR2 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
D02217 |
Raloxifene |
1件: 46 |
D08465 |
1件: JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
160 | Prostate cancer 4 genes, 4 drugs (DrugBank) and 51 diseases shown |
1件: IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
161 | Proteasome 2 genes, 2 drugs (DrugBank) and 13 diseases shown |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
1件: PSMB5 |
D03150 |
Bortezomib |
13件: 11, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 288, 331 |
162 | Protein digestion and absorption 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
163 | Proteoglycans in cancer 4 genes, 13 drugs (DrugBank) and 63 diseases shown |
1件: ESR1 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
D02217 |
Raloxifene |
1件: 46 |
D08465 |
1件: IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
164 | Proximal tubule bicarbonate reclamation 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
165 | Purine metabolism 13 genes, 8 drugs (DrugBank) and 44 diseases shown |
2件: IMPDH1, IMPDH2 |
D01392 |
Mizoribine |
8件: 46, 49, 51, 53, 66, 94, 222, 224 |
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D08860 |
Apremilast |
5件: 46, 50, 56, 97, 271 |
2件: PDE4A, PDE5A |
D00302 |
Dipyridamole |
5件: 46, 49, 51, 66, 224 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
1件: RRM1 |
D03546 |
Clofarabine |
9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
1件: XDH |
D00224 |
Allopurinol |
6件: 6, 46, 57, 66, 96, 97 |
166 | Pyrimidine metabolism 2 genes, 3 drugs (DrugBank) and 28 diseases shown |
1件: DHODH |
D00749 |
Leflunomide |
10件: 11, 40, 46, 49, 53, 66, 162, 224, 271, 300 |
1件: RRM1 |
D03546 |
Clofarabine |
9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
167 | Rap1 signaling pathway 9 genes, 8 drugs (DrugBank) and 35 diseases shown |
1件: ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
2件: ADORA2A, ADORA2B |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
1件: CNR1 |
D10915 |
Cannabidiol |
14件: 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
D00306 |
Dronabinol |
5件: 2, 13, 46, 271, 298 |
3件: GRIN1, GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
168 | Ras signaling pathway 7 genes, 4 drugs (DrugBank) and 21 diseases shown |
3件: ABL1, KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: GRIN1, GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
169 | Regulation of actin cytoskeleton 3 genes, 3 drugs (DrugBank) and 21 diseases shown |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
170 | Regulation of lipolysis in adipocytes 8 genes, 21 drugs (DrugBank) and 29 diseases shown |
1件: ADORA1 |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
2件: ADORA1, PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
3件: ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: PTGER3 |
D00419 |
Misoprostol |
2件: 46, 271 |
2件: PTGS1, PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
171 | Relaxin signaling pathway 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
172 | Renin secretion 16 genes, 11 drugs (DrugBank) and 69 diseases shown |
1件: ACE |
D00621 |
Enalapril |
4件: 19, 46, 66, 113 |
D07892 |
D00362 |
Lisinopril |
5件: 46, 66, 67, 113, 222 |
D08131 |
D00421 |
Ramipril |
7件: 46, 49, 66, 67, 113, 218, 257 |
1件: ADORA1 |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
4件: ADORA1, PDE1B, PDE3A, PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
3件: ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
2件: PTGER2, PTGER4 |
D00419 |
Misoprostol |
2件: 46, 271 |
173 | Renin-angiotensin system 3 genes, 5 drugs (DrugBank) and 23 diseases shown |
1件: ACE |
D00621 |
Enalapril |
4件: 19, 46, 66, 113 |
D07892 |
D00362 |
Lisinopril |
5件: 46, 66, 67, 113, 222 |
D08131 |
D00421 |
Ramipril |
7件: 46, 49, 66, 67, 113, 218, 257 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
2件: AGTR1, AGTR2 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
174 | Retrograde endocannabinoid signaling 18 genes, 23 drugs (DrugBank) and 35 diseases shown |
1件: CNR1 |
D10915 |
Cannabidiol |
14件: 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
D00306 |
Dronabinol |
5件: 2, 13, 46, 271, 298 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00293 |
Diazepam |
3件: 46, 155, 298 |
D02624 |
Eszopiclone |
3件: 6, 13, 46 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
175 | Rheumatoid arthritis 15 genes, 22 drugs (DrugBank) and 54 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
D03222 |
Belatacept |
1件: 46 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
1件: IL17A |
D11550 |
Bimekizumab |
3件: 46, 97, 271 |
D09967 |
Secukinumab |
7件: 13, 37, 41, 46, 160, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: LTB |
D08866 |
Baminercept |
4件: 13, 46, 53, 97 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
2件: TNFSF13, TNFSF13B |
D09704 |
Atacicept |
4件: 13, 46, 49, 66 |
1件: TNFSF13B |
D03068 |
Belimumab |
8件: 11, 43, 44, 46, 49, 51, 53, 222 |
D10083 |
Tabalumab |
2件: 46, 49 |
176 | RIG-I-like receptor signaling pathway 4 genes, 10 drugs (DrugBank) and 40 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
177 | Salivary secretion 10 genes, 2 drugs (DrugBank) and 10 diseases shown |
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
178 | Salmonella infection 5 genes, 5 drugs (DrugBank) and 20 diseases shown |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
179 | Serotonergic synapse 6 genes, 26 drugs (DrugBank) and 31 diseases shown |
3件: GABRB1, GABRB2, GABRB3 |
D00293 |
Diazepam |
3件: 46, 155, 298 |
D02624 |
Eszopiclone |
3件: 6, 13, 46 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
2件: PTGS1, PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
1件: SLC6A4 |
D00228 |
Amoxapine |
1件: 46 |
D00822 |
Citalopram |
3件: 8, 46, 127 |
D07704 |
D08222 |
Milnacipran |
2件: 46, 49 |
D02260 |
Paroxetine |
3件: 6, 13, 46 |
D02362 |
D05374 |
D05375 |
D00821 |
Venlafaxine |
3件: 6, 13, 46 |
D08670 |
180 | Shigellosis 6 genes, 13 drugs (DrugBank) and 68 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
181 | Signaling pathways regulating pluripotency of stem cells 3 genes, 6 drugs (DrugBank) and 17 diseases shown |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
3件: JAK1, JAK2, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
182 | Small cell lung cancer 2 genes, 18 drugs (DrugBank) and 24 diseases shown |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
183 | Sphingolipid signaling pathway 5 genes, 12 drugs (DrugBank) and 44 diseases shown |
1件: ADORA1 |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
2件: ADORA1, ADORA3 |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: OPRD1 |
D03783 |
Oxycodone |
7件: 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
184 | Staphylococcus aureus infection 4 genes, 4 drugs (DrugBank) and 22 diseases shown |
1件: IL10 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: PLG |
D01136 |
Tranexamic acid |
5件: 46, 70, 215, 227, 288 |
1件: PTAFR |
D07407 |
Rupatadine |
1件: 46 |
185 | Synaptic vesicle cycle 2 genes, 5 drugs (DrugBank) and 6 diseases shown |
2件: SLC6A2, SLC6A4 |
D00228 |
Amoxapine |
1件: 46 |
D08222 |
Milnacipran |
2件: 46, 49 |
D00821 |
Venlafaxine |
3件: 6, 13, 46 |
D08670 |
1件: SLC6A4 |
D00822 |
Citalopram |
3件: 8, 46, 127 |
D07704 |
D02260 |
Paroxetine |
3件: 6, 13, 46 |
D02362 |
D05374 |
D05375 |
186 | Systemic lupus erythematosus 7 genes, 12 drugs (DrugBank) and 51 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
D03222 |
Belatacept |
1件: 46 |
2件: GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
187 | T cell receptor signaling pathway 13 genes, 14 drugs (DrugBank) and 65 diseases shown |
3件: CD3D, CD3E, CD3G |
D08959 |
Otelixizumab |
1件: 46 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PDCD1 |
D10316 |
Nivolumab |
10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
188 | Taste transduction 10 genes, 10 drugs (DrugBank) and 25 diseases shown |
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 |
D00293 |
Diazepam |
3件: 46, 155, 298 |
D02624 |
Eszopiclone |
3件: 6, 13, 46 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
1件: PDE1B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
3件: SCN2A, SCN3A, SCN9A |
D01450 |
Bupivacaine |
7件: 46, 53, 70, 96, 168, 226, 298 |
D07552 |
D01287 |
Levobupivacaine |
1件: 46 |
D08116 |
D00358 |
Lidocaine |
10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
D04048 |
Ropivacaine |
3件: 36, 46, 70 |
D08490 |
2件: SCN3A, SCN9A |
D07299 |
Lacosamide |
3件: 2, 46, 149 |
189 | Terpenoid backbone biosynthesis 2 genes, 9 drugs (DrugBank) and 42 diseases shown |
1件: FDPS |
D00939 |
Alendronic acid |
7件: 19, 41, 46, 50, 271, 274, 299 |
D07119 |
D08056 |
Ibandronate |
2件: 46, 49 |
D00942 |
Risedronic acid |
7件: 46, 66, 93, 95, 96, 113, 274 |
D03234 |
D08484 |
D01968 |
Zoledronic acid |
11件: 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
D00893 |
Pravastatin |
9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 |
D08410 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
190 | TGF-beta signaling pathway 2 genes, 9 drugs (DrugBank) and 38 diseases shown |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
191 | Th1 and Th2 cell differentiation 16 genes, 12 drugs (DrugBank) and 62 diseases shown |
3件: CD3D, CD3E, CD3G |
D08959 |
Otelixizumab |
1件: 46 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
3件: JAK1, JAK2, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
192 | Th17 cell differentiation 22 genes, 21 drugs (DrugBank) and 85 diseases shown |
3件: CD3D, CD3E, CD3G |
D08959 |
Otelixizumab |
1件: 46 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
1件: IL17A |
D09967 |
Secukinumab |
7件: 13, 37, 41, 46, 160, 269, 271 |
2件: IL17A, IL17F |
D11550 |
Bimekizumab |
3件: 46, 97, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
3件: JAK1, JAK2, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
193 | Thermogenesis 6 genes, 7 drugs (DrugBank) and 60 diseases shown |
1件: ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: CNR1 |
D10915 |
Cannabidiol |
14件: 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
D00306 |
Dronabinol |
5件: 2, 13, 46, 271, 298 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
194 | Thyroid cancer 1 gene, 2 drugs (DrugBank) and 20 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
195 | Thyroid hormone signaling pathway 6 genes, 5 drugs (DrugBank) and 39 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
1件: ESR1 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
D02217 |
Raloxifene |
1件: 46 |
D08465 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
196 | Thyroid hormone synthesis 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
197 | Tight junction 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
198 | TNF signaling pathway 7 genes, 29 drugs (DrugBank) and 57 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: LTA |
D10187 |
Pateclizumab |
1件: 46 |
2件: LTA, TNF |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
199 | Toll-like receptor signaling pathway 10 genes, 15 drugs (DrugBank) and 50 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
D03222 |
Belatacept |
1件: 46 |
2件: IFNAR1, IFNAR2 |
D11082 |
Anifrolumab |
2件: 46, 49 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
200 | Toxoplasmosis 10 genes, 18 drugs (DrugBank) and 43 diseases shown |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
201 | Transcriptional misregulation in cancer 5 genes, 8 drugs (DrugBank) and 45 diseases shown |
1件: CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
D03222 |
Belatacept |
1件: 46 |
1件: IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
202 | Tuberculosis 19 genes, 27 drugs (DrugBank) and 74 diseases shown |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
1件: VDR |
D01518 |
Alfacalcidol |
6件: 41, 46, 49, 50, 96, 235 |
D00129 |
Calcitriol |
8件: 37, 46, 49, 66, 96, 158, 235, 326 |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D07578 |
Eldecalcitol |
1件: 46 |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
203 | Type I diabetes mellitus 9 genes, 14 drugs (DrugBank) and 50 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
D03222 |
Belatacept |
1件: 46 |
1件: IFNG |
D04242 |
Fontolizumab |
1件: 46 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: LTA |
D10187 |
Pateclizumab |
1件: 46 |
2件: LTA, TNF |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
204 | Type II diabetes mellitus 2 genes, 9 drugs (DrugBank) and 61 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
205 | Ubiquinone and other terpenoid-quinone biosynthesis 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: NQO1, VKORC1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
206 | Ubiquitin mediated proteolysis 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: KEAP1 |
D03846 |
Dimethyl fumarate |
5件: 13, 46, 49, 51, 86 |
207 | Vascular smooth muscle contraction 6 genes, 5 drugs (DrugBank) and 29 diseases shown |
1件: ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
2件: ADORA2A, ADORA2B |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
3件: ADRA1A, ADRA1B, ADRA1D |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
208 | VEGF signaling pathway 6 genes, 19 drugs (DrugBank) and 67 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D01545 |
Aceclofenac |
1件: 46 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
D00315 |
Etodolac |
1件: 46 |
D03710 |
Etoricoxib |
2件: 46, 271 |
D00330 |
Flurbiprofen |
2件: 13, 46 |
D01475 |
D02290 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
D00132 |
Ketoprofen |
1件: 46 |
D08149 |
Loxoprofen |
2件: 46, 271 |
D03714 |
Lumiracoxib |
1件: 46 |
D00969 |
Meloxicam |
4件: 46, 49, 271, 296 |
D00118 |
Naproxen |
3件: 13, 46, 271 |
D01049 |
Nimesulide |
1件: 46 |
D03716 |
Parecoxib |
2件: 46, 271 |
D02709 |
Valdecoxib |
1件: 46 |
209 | Viral carcinogenesis 5 genes, 9 drugs (DrugBank) and 19 diseases shown |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
1件: JAK1 |
D10308 |
Baricitinib |
8件: 41, 46, 49, 50, 93, 107, 265, 325 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10944 |
Itacitinib |
4件: 46, 60, 97, 228 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK3 |
D10653 |
Peficitinib |
1件: 46 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: SYK |
D09347 |
Fostamatinib |
4件: 46, 49, 61, 66 |
210 | Viral myocarditis 4 genes, 4 drugs (DrugBank) and 35 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
D03222 |
Belatacept |
1件: 46 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
211 | Viral protein interaction with cytokine and cytokine receptor 7 genes, 13 drugs (DrugBank) and 46 diseases shown |
4件: CCL2, IL10, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: LTA |
D10187 |
Pateclizumab |
1件: 46 |
2件: LTA, TNF |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |
212 | Wnt signaling pathway 5 genes, 2 drugs (DrugBank) and 55 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
213 | Yersinia infection 7 genes, 12 drugs (DrugBank) and 46 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6 |
D10080 |
Sirukumab |
2件: 41, 46 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
1件: NFKB1 |
D01146 |
Iguratimod |
3件: 46, 53, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D00742 |
Etanercept |
15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D09944 |
Ozoralizumab |
1件: 46 |
D05393 |
Pegsunercept |
1件: 46 |