No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Acute myeloid leukemia 2 genes, 3 drugs (DrugBank) and 41 diseases shown |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2 | Adherens junction 2 genes, 2 drugs (DrugBank) and 7 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: FGFR1 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
3 | Adipocytokine signaling pathway 3 genes, 5 drugs (DrugBank) and 51 diseases shown |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
4 | Adrenergic signaling in cardiomyocytes 4 genes, 1 drug (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
5 | African trypanosomiasis 4 genes, 4 drugs (DrugBank) and 28 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
6 | AGE-RAGE signaling pathway in diabetic complications 9 genes, 6 drugs (DrugBank) and 29 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
7 | Alcoholism 1 gene, 3 drugs (DrugBank) and 6 diseases shown |
1件: DRD2 |
D00702 |
Buspirone |
2件: 6, 51 |
D07593 |
D01745 |
Domperidone |
5件: 6, 13, 17, 51, 230 |
D07868 |
D01348 |
Terguride |
2件: 51, 86 |
8 | Aldosterone synthesis and secretion 4 genes, 1 drug (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
9 | Allograft rejection 4 genes, 4 drugs (DrugBank) and 37 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
10 | Alzheimer disease 11 genes, 6 drugs (DrugBank) and 46 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
11 | Amoebiasis 7 genes, 5 drugs (DrugBank) and 29 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
12 | Amphetamine addiction 7 genes, 2 drugs (DrugBank) and 32 diseases shown |
2件: CACNA1C, CACNA1D |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
13 | AMPK signaling pathway 2 genes, 4 drugs (DrugBank) and 52 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
14 | Amyotrophic lateral sclerosis (ALS) 6 genes, 4 drugs (DrugBank) and 42 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
15 | Antifolate resistance 5 genes, 5 drugs (DrugBank) and 48 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
16 | Antigen processing and presentation 1 gene, 3 drugs (DrugBank) and 25 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
17 | Apelin signaling pathway 2 genes, 2 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDE3B |
D01896 |
Cilostazol |
2件: 51, 70 |
18 | Apoptosis 1 gene, 3 drugs (DrugBank) and 25 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
19 | Arachidonic acid metabolism 2 genes, 2 drugs (DrugBank) and 16 diseases shown |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
20 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) 4 genes, 1 drug (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
21 | Asthma 2 genes, 3 drugs (DrugBank) and 25 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
22 | Autoimmune thyroid disease 3 genes, 2 drugs (DrugBank) and 28 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL10 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
23 | Autophagy - animal 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
24 | Autophagy - other 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
25 | Axon guidance 7 genes, 4 drugs (DrugBank) and 39 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
26 | B cell receptor signaling pathway 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
27 | Bile secretion 1 gene, 3 drugs (DrugBank) and 29 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
28 | Bladder cancer 2 genes, 2 drugs (DrugBank) and 7 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: FGFR3 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
29 | Breast cancer 5 genes, 5 drugs (DrugBank) and 42 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: FGFR1, FLT4 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
30 | C-type lectin receptor signaling pathway 10 genes, 7 drugs (DrugBank) and 52 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
31 | Calcium signaling pathway 19 genes, 15 drugs (DrugBank) and 50 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: HRH1 |
D00300 |
Diphenhydramine |
5件: 49, 51, 70, 86, 256 |
D00669 |
D02419 |
D03285 |
D03360 |
D03854 |
1件: HTR4 |
D09205 |
Prucalopride |
3件: 13, 51, 96 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGER1 |
D00180 |
Alprostadil |
2件: 51, 70 |
D02705 |
1件: TBXA2R |
D01896 |
Cilostazol |
2件: 51, 70 |
D04500 |
Ifetroban |
3件: 51, 86, 113 |
32 | cAMP signaling pathway 11 genes, 10 drugs (DrugBank) and 22 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: DRD2 |
D01745 |
Domperidone |
5件: 6, 13, 17, 51, 230 |
D07868 |
D01348 |
Terguride |
2件: 51, 86 |
2件: DRD2, HTR1A |
D00702 |
Buspirone |
2件: 6, 51 |
D07593 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
1件: HTR4 |
D09205 |
Prucalopride |
3件: 13, 51, 96 |
2件: PDE3A, PDE3B |
D01896 |
Cilostazol |
2件: 51, 70 |
1件: PDE4A |
D00302 |
Dipyridamole |
5件: 46, 49, 51, 66, 224 |
33 | Carbohydrate digestion and absorption 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: CACNA1D |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
34 | Cardiac muscle contraction 4 genes, 1 drug (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
35 | Cell adhesion molecules (CAMs) 3 genes, 2 drugs (DrugBank) and 25 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: PDCD1 |
D10316 |
Nivolumab |
10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 |
36 | Cell cycle 4 genes, 3 drugs (DrugBank) and 15 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
37 | Cellular senescence 12 genes, 7 drugs (DrugBank) and 58 diseases shown |
1件: CACNA1D |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: IL1A |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL1A, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
38 | Central carbon metabolism in cancer 8 genes, 5 drugs (DrugBank) and 42 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
5件: FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
39 | cGMP-PKG signaling pathway 17 genes, 10 drugs (DrugBank) and 45 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
2件: PDE3A, PDE3B |
D01896 |
Cilostazol |
2件: 51, 70 |
1件: PDE5A |
D00302 |
Dipyridamole |
5件: 46, 49, 51, 66, 224 |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
D02008 |
Tadalafil |
6件: 6, 51, 75, 84, 86, 113 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
40 | Chagas disease (American trypanosomiasis) 8 genes, 5 drugs (DrugBank) and 29 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
41 | Chemical carcinogenesis 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
42 | Chemokine signaling pathway 4 genes, 3 drugs (DrugBank) and 18 diseases shown |
1件: CCL2 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
2件: JAK2, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
43 | Choline metabolism in cancer 4 genes, 5 drugs (DrugBank) and 42 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
44 | Cholinergic synapse 5 genes, 2 drugs (DrugBank) and 12 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
45 | Chronic myeloid leukemia 4 genes, 3 drugs (DrugBank) and 15 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
46 | Circadian entrainment 5 genes, 2 drugs (DrugBank) and 9 diseases shown |
2件: CACNA1C, CACNA1D |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
47 | Cocaine addiction 1 gene, 3 drugs (DrugBank) and 6 diseases shown |
1件: DRD2 |
D00702 |
Buspirone |
2件: 6, 51 |
D07593 |
D01745 |
Domperidone |
5件: 6, 13, 17, 51, 230 |
D07868 |
D01348 |
Terguride |
2件: 51, 86 |
48 | Collecting duct acid secretion 2 genes, 2 drugs (DrugBank) and 16 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
D00724 |
Rabeprazole |
2件: 2, 51 |
D08463 |
49 | Colorectal cancer 5 genes, 3 drugs (DrugBank) and 37 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
50 | Cortisol synthesis and secretion 4 genes, 1 drug (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
51 | Cushing syndrome 5 genes, 2 drugs (DrugBank) and 8 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
52 | Cytokine-cytokine receptor interaction 17 genes, 13 drugs (DrugBank) and 54 diseases shown |
6件: CCL2, IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CSF2RA |
D05712 |
Regramostim |
4件: 11, 46, 51, 229 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
1件: IL17RA |
D10061 |
Brodalumab |
2件: 37, 51 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: PRL |
D01348 |
Terguride |
2件: 51, 86 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
1件: TNFRSF8 |
D09587 |
Brentuximab vedotin |
2件: 49, 51 |
1件: TNFSF13B |
D03068 |
Belimumab |
8件: 11, 43, 44, 46, 49, 51, 53, 222 |
53 | Cytosolic DNA-sensing pathway 2 genes, 3 drugs (DrugBank) and 16 diseases shown |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
54 | Dilated cardiomyopathy (DCM) 8 genes, 5 drugs (DrugBank) and 27 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
55 | Dopaminergic synapse 6 genes, 5 drugs (DrugBank) and 35 diseases shown |
2件: CACNA1C, CACNA1D |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: DRD2 |
D00702 |
Buspirone |
2件: 6, 51 |
D07593 |
D01745 |
Domperidone |
5件: 6, 13, 17, 51, 230 |
D07868 |
D01348 |
Terguride |
2件: 51, 86 |
3件: PPP3CA, PPP3CB, PPP3CC |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
56 | Drug metabolism - other enzymes 3 genes, 4 drugs (DrugBank) and 38 diseases shown |
2件: IMPDH1, IMPDH2 |
D01392 |
Mizoribine |
8件: 46, 49, 51, 53, 66, 94, 222, 224 |
D00752 |
Mycophenolate mofetil |
32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
D05094 |
D05095 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
1件: RRM1 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
57 | EGFR tyrosine kinase inhibitor resistance 11 genes, 9 drugs (DrugBank) and 57 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
5件: FGFR2, FGFR3, KDR, PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
2件: JAK1, JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
58 | Endocrine resistance 2 genes, 2 drugs (DrugBank) and 36 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
59 | Endocytosis 5 genes, 5 drugs (DrugBank) and 18 diseases shown |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
3件: FGFR2, FGFR3, PDGFRA |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
60 | Endometrial cancer 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
61 | Epithelial cell signaling in Helicobacter pylori infection 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
62 | Epstein-Barr virus infection 5 genes, 4 drugs (DrugBank) and 26 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
3件: JAK1, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
63 | ErbB signaling pathway 3 genes, 4 drugs (DrugBank) and 41 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
64 | Estrogen signaling pathway 2 genes, 2 drugs (DrugBank) and 5 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: OPRM1 |
D08639 |
Trimebutine |
1件: 51 |
65 | Fc epsilon RI signaling pathway 1 gene, 3 drugs (DrugBank) and 25 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
66 | Fluid shear stress and atherosclerosis 6 genes, 6 drugs (DrugBank) and 31 diseases shown |
4件: CCL2, IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
1件: KDR |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: KEAP1 |
D03846 |
Dimethyl fumarate |
5件: 13, 46, 49, 51, 86 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
67 | Focal adhesion 6 genes, 4 drugs (DrugBank) and 15 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
68 | Folate biosynthesis 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
69 | FoxO signaling pathway 6 genes, 4 drugs (DrugBank) and 16 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
70 | GABAergic synapse 4 genes, 1 drug (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
71 | Gap junction 16 genes, 9 drugs (DrugBank) and 22 diseases shown |
1件: DRD2 |
D00702 |
Buspirone |
2件: 6, 51 |
D07593 |
D01745 |
Domperidone |
5件: 6, 13, 17, 51, 230 |
D07868 |
D01348 |
Terguride |
2件: 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 |
D09587 |
Brentuximab vedotin |
2件: 49, 51 |
72 | Gastric acid secretion 2 genes, 2 drugs (DrugBank) and 16 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
D00724 |
Rabeprazole |
2件: 2, 51 |
D08463 |
73 | Gastric cancer 6 genes, 4 drugs (DrugBank) and 38 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: FGFR2 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
74 | Glioma 4 genes, 5 drugs (DrugBank) and 42 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
75 | Glucagon signaling pathway 6 genes, 2 drugs (DrugBank) and 31 diseases shown |
1件: PDE3B |
D01896 |
Cilostazol |
2件: 51, 70 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
76 | Glutamatergic synapse 7 genes, 2 drugs (DrugBank) and 32 diseases shown |
2件: CACNA1C, CACNA1D |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
77 | Glutathione metabolism 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: RRM1 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
78 | GnRH secretion 4 genes, 1 drug (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
79 | GnRH signaling pathway 6 genes, 3 drugs (DrugBank) and 12 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: GNRHR |
D00989 |
Leuprolide |
5件: 1, 2, 3, 51, 76 |
80 | Graft-versus-host disease 6 genes, 5 drugs (DrugBank) and 39 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
81 | Growth hormone synthesis, secretion and action 6 genes, 3 drugs (DrugBank) and 42 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
82 | Hematopoietic cell lineage 9 genes, 10 drugs (DrugBank) and 69 diseases shown |
1件: CSF2RA |
D05712 |
Regramostim |
4件: 11, 46, 51, 229 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MS4A1 |
D02994 |
Rituximab |
42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
83 | Hepatitis B 9 genes, 5 drugs (DrugBank) and 27 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
84 | Hepatitis C 4 genes, 5 drugs (DrugBank) and 28 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
85 | Hepatocellular carcinoma 6 genes, 4 drugs (DrugBank) and 37 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: KEAP1 |
D03846 |
Dimethyl fumarate |
5件: 13, 46, 49, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
86 | Herpes simplex virus 1 infection 8 genes, 6 drugs (DrugBank) and 53 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
87 | HIF-1 signaling pathway 5 genes, 6 drugs (DrugBank) and 52 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: FLT1 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
88 | Hippo signaling pathway 3 genes, 1 drug (DrugBank) and 4 diseases shown |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
89 | Human cytomegalovirus infection 17 genes, 16 drugs (DrugBank) and 74 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: JAK1 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGER1 |
D00180 |
Alprostadil |
2件: 51, 70 |
D02705 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
90 | Human immunodeficiency virus 1 infection 8 genes, 6 drugs (DrugBank) and 58 diseases shown |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
91 | Human papillomavirus infection 7 genes, 10 drugs (DrugBank) and 58 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
92 | Human T-cell leukemia virus 1 infection 12 genes, 6 drugs (DrugBank) and 44 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: JAK1, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
93 | Hypertrophic cardiomyopathy (HCM) 9 genes, 5 drugs (DrugBank) and 27 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
94 | IL-17 signaling pathway 6 genes, 7 drugs (DrugBank) and 40 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL17RA |
D10061 |
Brodalumab |
2件: 37, 51 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
95 | Inflammatory bowel disease (IBD) 8 genes, 5 drugs (DrugBank) and 29 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
96 | Inflammatory mediator regulation of TRP channels 2 genes, 3 drugs (DrugBank) and 17 diseases shown |
1件: HRH1 |
D00300 |
Diphenhydramine |
5件: 49, 51, 70, 86, 256 |
D00669 |
D02419 |
D03285 |
D03360 |
D03854 |
1件: IL1B |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
97 | Influenza A 8 genes, 5 drugs (DrugBank) and 28 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
98 | Insulin resistance 3 genes, 4 drugs (DrugBank) and 50 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
99 | Insulin secretion 5 genes, 3 drugs (DrugBank) and 16 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: SNAP25 |
D02735 |
Botulinum Toxin Type B |
3件: 2, 6, 51 |
D00783 |
Botulinum toxin type A |
13件: 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226 |
100 | Insulin signaling pathway 2 genes, 2 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDE3B |
D01896 |
Cilostazol |
2件: 51, 70 |
101 | Intestinal immune network for IgA production 7 genes, 6 drugs (DrugBank) and 34 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TGFB1 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNFSF13B |
D03068 |
Belimumab |
8件: 11, 43, 44, 46, 49, 51, 53, 222 |
102 | JAK-STAT signaling pathway 14 genes, 12 drugs (DrugBank) and 66 diseases shown |
1件: CSF2RA |
D05712 |
Regramostim |
4件: 11, 46, 51, 229 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: PRL |
D01348 |
Terguride |
2件: 51, 86 |
103 | Kaposi sarcoma-associated herpesvirus infection 12 genes, 8 drugs (DrugBank) and 66 diseases shown |
1件: CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
104 | Legionellosis 3 genes, 4 drugs (DrugBank) and 28 diseases shown |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
105 | Leishmaniasis 10 genes, 8 drugs (DrugBank) and 40 diseases shown |
4件: IL10, IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: JAK1, JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
106 | Leukocyte transendothelial migration 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
107 | Long-term depression 3 genes, 1 drug (DrugBank) and 6 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
108 | Long-term potentiation 6 genes, 2 drugs (DrugBank) and 32 diseases shown |
1件: CACNA1C |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
109 | Longevity regulating pathway 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
110 | Longevity regulating pathway - multiple species 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
111 | Malaria 8 genes, 5 drugs (DrugBank) and 29 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
112 | MAPK signaling pathway 25 genes, 11 drugs (DrugBank) and 53 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
113 | Measles 6 genes, 4 drugs (DrugBank) and 20 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
3件: JAK1, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
114 | Melanogenesis 2 genes, 4 drugs (DrugBank) and 19 diseases shown |
1件: EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
115 | Melanoma 4 genes, 4 drugs (DrugBank) and 15 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
3件: FGFR1, PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
116 | Metabolic pathways 17 genes, 17 drugs (DrugBank) and 80 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
D00724 |
Rabeprazole |
2件: 2, 51 |
D08463 |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
2件: IMPDH1, IMPDH2 |
D01392 |
Mizoribine |
8件: 46, 49, 51, 53, 66, 94, 222, 224 |
D00752 |
Mycophenolate mofetil |
32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
D05094 |
D05095 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
2件: PDE3A, PDE3B |
D01896 |
Cilostazol |
2件: 51, 70 |
2件: PDE4A, PDE5A |
D00302 |
Dipyridamole |
5件: 46, 49, 51, 66, 224 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
D02008 |
Tadalafil |
6件: 6, 51, 75, 84, 86, 113 |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: RRM1 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
117 | MicroRNAs in cancer 8 genes, 8 drugs (DrugBank) and 49 diseases shown |
2件: ABL1, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: ABL1, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
3件: FGFR3, PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: TGFB2 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
118 | Morphine addiction 4 genes, 3 drugs (DrugBank) and 6 diseases shown |
1件: OPRM1 |
D08639 |
Trimebutine |
1件: 51 |
2件: PDE3A, PDE3B |
D01896 |
Cilostazol |
2件: 51, 70 |
1件: PDE4A |
D00302 |
Dipyridamole |
5件: 46, 49, 51, 66, 224 |
119 | mTOR signaling pathway 2 genes, 4 drugs (DrugBank) and 50 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
120 | Natural killer cell mediated cytotoxicity 6 genes, 4 drugs (DrugBank) and 42 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
121 | Necroptosis 7 genes, 5 drugs (DrugBank) and 28 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
122 | Neuroactive ligand-receptor interaction 15 genes, 20 drugs (DrugBank) and 67 diseases shown |
1件: CNR2 |
D11312 |
Ajulemic acid |
3件: 50, 51, 299 |
1件: DRD2 |
D01745 |
Domperidone |
5件: 6, 13, 17, 51, 230 |
D07868 |
2件: DRD2, HTR1A |
D00702 |
Buspirone |
2件: 6, 51 |
D07593 |
2件: DRD2, PRL |
D01348 |
Terguride |
2件: 51, 86 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
1件: GNRHR |
D00989 |
Leuprolide |
5件: 1, 2, 3, 51, 76 |
1件: HRH1 |
D00300 |
Diphenhydramine |
5件: 49, 51, 70, 86, 256 |
D00669 |
D02419 |
D03285 |
D03360 |
D03854 |
1件: HTR4 |
D09205 |
Prucalopride |
3件: 13, 51, 96 |
1件: NR3C1 |
D00407 |
Methylprednisolone |
36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 |
D00751 |
D00979 |
D05000 |
D05001 |
D05002 |
D00472 |
Prednisolone |
38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
D00980 |
D00981 |
D00982 |
D01239 |
D01998 |
D02156 |
D03301 |
D00473 |
Prednisone |
44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
2件: OPRK1, OPRM1 |
D08639 |
Trimebutine |
1件: 51 |
1件: PTGER1 |
D00180 |
Alprostadil |
2件: 51, 70 |
D02705 |
1件: PTGIR |
D02721 |
Iloprost |
4件: 51, 84, 85, 86 |
D09994 |
Selexipag |
5件: 51, 70, 84, 86, 88 |
D06213 |
Treprostinil |
5件: 51, 84, 85, 86, 88 |
1件: TBXA2R |
D01896 |
Cilostazol |
2件: 51, 70 |
D04500 |
Ifetroban |
3件: 51, 86, 113 |
123 | Neurotrophin signaling pathway 1 gene, 2 drugs (DrugBank) and 13 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
124 | NF-kappa B signaling pathway 4 genes, 7 drugs (DrugBank) and 42 diseases shown |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
1件: TNFSF13B |
D03068 |
Belimumab |
8件: 11, 43, 44, 46, 49, 51, 53, 222 |
125 | NOD-like receptor signaling pathway 6 genes, 5 drugs (DrugBank) and 28 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
126 | Non-alcoholic fatty liver disease (NAFLD) 6 genes, 6 drugs (DrugBank) and 36 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: TGFB1 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
127 | Non-small cell lung cancer 2 genes, 2 drugs (DrugBank) and 13 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
128 | One carbon pool by folate 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
129 | Oocyte meiosis 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
130 | Osteoclast differentiation 12 genes, 7 drugs (DrugBank) and 46 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
2件: TGFB1, TGFB2 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
131 | Ovarian steroidogenesis 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
132 | Oxidative phosphorylation 2 genes, 2 drugs (DrugBank) and 16 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
D00724 |
Rabeprazole |
2件: 2, 51 |
D08463 |
133 | Oxytocin signaling pathway 14 genes, 6 drugs (DrugBank) and 46 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
134 | Pancreatic cancer 6 genes, 4 drugs (DrugBank) and 42 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: JAK1 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
135 | Parathyroid hormone synthesis, secretion and action 3 genes, 3 drugs (DrugBank) and 11 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: FGFR1 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: PDE4A |
D00302 |
Dipyridamole |
5件: 46, 49, 51, 66, 224 |
136 | Parkinson disease 1 gene, 3 drugs (DrugBank) and 6 diseases shown |
1件: DRD2 |
D00702 |
Buspirone |
2件: 6, 51 |
D07593 |
D01745 |
Domperidone |
5件: 6, 13, 17, 51, 230 |
D07868 |
D01348 |
Terguride |
2件: 51, 86 |
137 | Pathogenic Escherichia coli infection 13 genes, 7 drugs (DrugBank) and 36 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 |
D09587 |
Brentuximab vedotin |
2件: 49, 51 |
138 | Pathways in cancer 26 genes, 20 drugs (DrugBank) and 76 diseases shown |
3件: ABL1, KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
4件: ABL1, KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: CSF2RA |
D05712 |
Regramostim |
4件: 11, 46, 51, 229 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
6件: FGFR1, FGFR2, FGFR3, FLT4, PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
3件: JAK1, JAK2, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: KEAP1 |
D03846 |
Dimethyl fumarate |
5件: 13, 46, 49, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PTGER1 |
D00180 |
Alprostadil |
2件: 51, 70 |
D02705 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
139 | PD-L1 expression and PD-1 checkpoint pathway in cancer 10 genes, 5 drugs (DrugBank) and 54 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: JAK1, JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDCD1 |
D10316 |
Nivolumab |
10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
140 | Pertussis 5 genes, 4 drugs (DrugBank) and 28 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
141 | Phagosome 9 genes, 1 drug (DrugBank) and 2 diseases shown |
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 |
D09587 |
Brentuximab vedotin |
2件: 49, 51 |
142 | Phospholipase D signaling pathway 5 genes, 5 drugs (DrugBank) and 42 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
143 | PI3K-Akt signaling pathway 18 genes, 11 drugs (DrugBank) and 64 diseases shown |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
3件: JAK1, JAK2, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PRL |
D01348 |
Terguride |
2件: 51, 86 |
144 | Platelet activation 6 genes, 8 drugs (DrugBank) and 21 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: PTGIR |
D02721 |
Iloprost |
4件: 51, 84, 85, 86 |
D09994 |
Selexipag |
5件: 51, 70, 84, 86, 88 |
D06213 |
Treprostinil |
5件: 51, 84, 85, 86, 88 |
1件: PTGS1 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: TBXA2R |
D01896 |
Cilostazol |
2件: 51, 70 |
D04500 |
Ifetroban |
3件: 51, 86, 113 |
145 | Primary immunodeficiency 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
146 | Prion diseases 3 genes, 3 drugs (DrugBank) and 16 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
147 | Progesterone-mediated oocyte maturation 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: PDE3B |
D01896 |
Cilostazol |
2件: 51, 70 |
148 | Prolactin signaling pathway 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: PRL |
D01348 |
Terguride |
2件: 51, 86 |
149 | Prostate cancer 6 genes, 5 drugs (DrugBank) and 42 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
4件: FGFR1, FGFR2, PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
150 | Proteasome 1 gene, 1 drug (DrugBank) and 13 diseases shown |
1件: PSMB5 |
D03150 |
Bortezomib |
13件: 11, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 288, 331 |
151 | Proteoglycans in cancer 7 genes, 7 drugs (DrugBank) and 51 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: FGFR1, KDR |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: TGFB1, TGFB2 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
152 | Purine metabolism 10 genes, 9 drugs (DrugBank) and 52 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
2件: IMPDH1, IMPDH2 |
D01392 |
Mizoribine |
8件: 46, 49, 51, 53, 66, 94, 222, 224 |
D00752 |
Mycophenolate mofetil |
32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
D05094 |
D05095 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
2件: PDE3A, PDE3B |
D01896 |
Cilostazol |
2件: 51, 70 |
2件: PDE4A, PDE5A |
D00302 |
Dipyridamole |
5件: 46, 49, 51, 66, 224 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
D02008 |
Tadalafil |
6件: 6, 51, 75, 84, 86, 113 |
1件: RRM1 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
153 | Pyrimidine metabolism 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: RRM1 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
154 | Rap1 signaling pathway 11 genes, 7 drugs (DrugBank) and 17 diseases shown |
1件: DRD2 |
D00702 |
Buspirone |
2件: 6, 51 |
D07593 |
D01745 |
Domperidone |
5件: 6, 13, 17, 51, 230 |
D07868 |
D01348 |
Terguride |
2件: 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
155 | Ras signaling pathway 11 genes, 4 drugs (DrugBank) and 15 diseases shown |
3件: ABL1, KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
4件: ABL1, KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
156 | Regulation of actin cytoskeleton 7 genes, 5 drugs (DrugBank) and 18 diseases shown |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
5件: FGFR1, FGFR2, FGFR3, PDGFRA, PDGFRB |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
157 | Regulation of lipolysis in adipocytes 3 genes, 3 drugs (DrugBank) and 16 diseases shown |
1件: PDE3B |
D01896 |
Cilostazol |
2件: 51, 70 |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
158 | Relaxin signaling pathway 3 genes, 4 drugs (DrugBank) and 15 diseases shown |
1件: EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: TGFB1 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
159 | Renal cell carcinoma 3 genes, 1 drug (DrugBank) and 4 diseases shown |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
160 | Renin secretion 15 genes, 7 drugs (DrugBank) and 40 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
2件: PDE3A, PDE3B |
D01896 |
Cilostazol |
2件: 51, 70 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
161 | Retrograde endocannabinoid signaling 5 genes, 3 drugs (DrugBank) and 19 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
162 | Rheumatoid arthritis 12 genes, 8 drugs (DrugBank) and 42 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: FLT1 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
1件: TNFSF13B |
D03068 |
Belimumab |
8件: 11, 43, 44, 46, 49, 51, 53, 222 |
163 | RIG-I-like receptor signaling pathway 1 gene, 3 drugs (DrugBank) and 25 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
164 | Salivary secretion 3 genes, 1 drug (DrugBank) and 6 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
165 | Salmonella infection 3 genes, 3 drugs (DrugBank) and 16 diseases shown |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
166 | Serotonergic synapse 8 genes, 5 drugs (DrugBank) and 20 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: HTR1A |
D00702 |
Buspirone |
2件: 6, 51 |
D07593 |
1件: HTR4 |
D09205 |
Prucalopride |
3件: 13, 51, 96 |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
167 | Shigellosis 5 genes, 8 drugs (DrugBank) and 57 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
168 | Signaling pathways regulating pluripotency of stem cells 6 genes, 2 drugs (DrugBank) and 12 diseases shown |
3件: FGFR1, FGFR2, FGFR3 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
3件: JAK1, JAK2, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
169 | Small cell lung cancer 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
170 | Sphingolipid signaling pathway 1 gene, 3 drugs (DrugBank) and 25 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
171 | Staphylococcus aureus infection 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: IL10 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
172 | Synaptic vesicle cycle 1 gene, 2 drugs (DrugBank) and 13 diseases shown |
1件: SNAP25 |
D02735 |
Botulinum Toxin Type B |
3件: 2, 6, 51 |
D00783 |
Botulinum toxin type A |
13件: 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226 |
173 | Systemic lupus erythematosus 4 genes, 4 drugs (DrugBank) and 37 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
174 | T cell receptor signaling pathway 8 genes, 5 drugs (DrugBank) and 44 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: PDCD1 |
D10316 |
Nivolumab |
10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
175 | Taste transduction 2 genes, 2 drugs (DrugBank) and 5 diseases shown |
1件: CACNA1C |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: HTR1A |
D00702 |
Buspirone |
2件: 6, 51 |
D07593 |
176 | Terpenoid backbone biosynthesis 1 gene, 3 drugs (DrugBank) and 29 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
177 | TGF-beta signaling pathway 4 genes, 4 drugs (DrugBank) and 26 diseases shown |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
178 | Th1 and Th2 cell differentiation 9 genes, 2 drugs (DrugBank) and 33 diseases shown |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
179 | Th17 cell differentiation 14 genes, 8 drugs (DrugBank) and 63 diseases shown |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TGFB1 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
180 | Thermogenesis 2 genes, 2 drugs (DrugBank) and 37 diseases shown |
1件: FGFR1 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
181 | Thyroid hormone signaling pathway 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
182 | Tight junction 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: CACNA1D |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
183 | TNF signaling pathway 5 genes, 6 drugs (DrugBank) and 39 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
184 | Toll-like receptor signaling pathway 5 genes, 5 drugs (DrugBank) and 39 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
185 | Toxoplasmosis 8 genes, 5 drugs (DrugBank) and 27 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
186 | Transcriptional misregulation in cancer 3 genes, 4 drugs (DrugBank) and 32 diseases shown |
1件: CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: FLT1 |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
187 | Tuberculosis 15 genes, 7 drugs (DrugBank) and 46 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: JAK1, JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
188 | Type I diabetes mellitus 5 genes, 5 drugs (DrugBank) and 39 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL1A, IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
189 | Type II diabetes mellitus 4 genes, 5 drugs (DrugBank) and 50 diseases shown |
2件: CACNA1C, CACNA1D |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
190 | Ubiquitin mediated proteolysis 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: KEAP1 |
D03846 |
Dimethyl fumarate |
5件: 13, 46, 49, 51, 86 |
191 | Vascular smooth muscle contraction 9 genes, 8 drugs (DrugBank) and 16 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00615 |
Amlodipine |
4件: 51, 65, 67, 298 |
D02914 |
D07450 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: PTGIR |
D02721 |
Iloprost |
4件: 51, 84, 85, 86 |
D09994 |
Selexipag |
5件: 51, 70, 84, 86, 88 |
D06213 |
Treprostinil |
5件: 51, 84, 85, 86, 88 |
192 | VEGF signaling pathway 7 genes, 4 drugs (DrugBank) and 40 diseases shown |
1件: KDR |
D10481 |
Nintedanib |
4件: 51, 85, 89, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
193 | Viral carcinogenesis 2 genes, 1 drug (DrugBank) and 9 diseases shown |
2件: JAK1, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
194 | Viral myocarditis 3 genes, 3 drugs (DrugBank) and 34 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
195 | Viral protein interaction with cytokine and cytokine receptor 6 genes, 5 drugs (DrugBank) and 36 diseases shown |
4件: CCL2, IL10, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
196 | Wnt signaling pathway 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
197 | Yersinia infection 5 genes, 4 drugs (DrugBank) and 28 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D06635 |
Rilonacept |
4件: 51, 106, 107, 266 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |