No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Adipocytokine signaling pathway 4 genes, 2 drugs (DrugBank) and 11 diseases shown |
3件: CPT1A, CPT1B, CPT1C |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2 | Adrenergic signaling in cardiomyocytes 9 genes, 9 drugs (DrugBank) and 27 diseases shown |
3件: ADRA1A, ADRA1B, ADRA1D |
D01307 |
Midodrine |
3件: 6, 17, 58 |
D08220 |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
D00601 |
Metoprolol |
7件: 17, 57, 58, 66, 113, 193, 226 |
D02358 |
D05011 |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
3 | African trypanosomiasis 4 genes, 1 drug (DrugBank) and 10 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4 | AGE-RAGE signaling pathway in diabetic complications 6 genes, 5 drugs (DrugBank) and 26 diseases shown |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5 | Alcoholism 2 genes, 2 drugs (DrugBank) and 5 diseases shown |
1件: ADORA2A |
D05711 |
Regadenoson |
1件: 58 |
2件: ADORA2A, ADORA2B |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
6 | Aldosterone synthesis and secretion 5 genes, 6 drugs (DrugBank) and 24 diseases shown |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
7 | Aldosterone-regulated sodium reabsorption 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: NR3C2 |
D00443 |
Spironolactone |
6件: 58, 67, 86, 113, 218, 225 |
8 | Allograft rejection 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
9 | Alzheimer disease 12 genes, 5 drugs (DrugBank) and 51 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: MME |
D10225 |
Sacubitril |
1件: 58 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
10 | Amoebiasis 4 genes, 1 drug (DrugBank) and 10 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
11 | Amphetamine addiction 7 genes, 3 drugs (DrugBank) and 47 diseases shown |
2件: CACNA1C, CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
12 | AMPK signaling pathway 5 genes, 3 drugs (DrugBank) and 20 diseases shown |
1件: ADRA1A |
D01307 |
Midodrine |
3件: 6, 17, 58 |
D08220 |
3件: CPT1A, CPT1B, CPT1C |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
13 | Amyotrophic lateral sclerosis (ALS) 6 genes, 2 drugs (DrugBank) and 48 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
14 | Antifolate resistance 3 genes, 1 drug (DrugBank) and 10 diseases shown |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
15 | Antigen processing and presentation 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
16 | Apelin signaling pathway 1 gene, 4 drugs (DrugBank) and 21 diseases shown |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
17 | Apoptosis 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
18 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
19 | Asthma 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
20 | Autoimmune thyroid disease 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: IL10 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
21 | Axon guidance 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
22 | B cell receptor signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
23 | Bile secretion 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
24 | C-type lectin receptor signaling pathway 9 genes, 2 drugs (DrugBank) and 48 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
25 | Calcium signaling pathway 16 genes, 12 drugs (DrugBank) and 63 diseases shown |
1件: ADORA2A |
D05711 |
Regadenoson |
1件: 58 |
2件: ADORA2A, ADORA2B |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
3件: ADRA1A, ADRA1B, ADRA1D |
D01307 |
Midodrine |
3件: 6, 17, 58 |
D08220 |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
D00601 |
Metoprolol |
7件: 17, 57, 58, 66, 113, 193, 226 |
D02358 |
D05011 |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
26 | cAMP signaling pathway 7 genes, 6 drugs (DrugBank) and 15 diseases shown |
2件: ADORA1, ADORA2A |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
1件: ADORA2A |
D05711 |
Regadenoson |
1件: 58 |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
D00601 |
Metoprolol |
7件: 17, 57, 58, 66, 113, 193, 226 |
D02358 |
D05011 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
27 | Carbohydrate digestion and absorption 1 gene, 2 drugs (DrugBank) and 4 diseases shown |
1件: CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
28 | Cardiac muscle contraction 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
29 | Cellular senescence 8 genes, 4 drugs (DrugBank) and 51 diseases shown |
1件: CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
2件: IL1A, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
30 | cGMP-PKG signaling pathway 16 genes, 11 drugs (DrugBank) and 63 diseases shown |
2件: ADORA1, ADORA3 |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
3件: ADRA1A, ADRA1B, ADRA1D |
D01307 |
Midodrine |
3件: 6, 17, 58 |
D08220 |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
D00601 |
Metoprolol |
7件: 17, 57, 58, 66, 113, 193, 226 |
D02358 |
D05011 |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
31 | Chagas disease (American trypanosomiasis) 5 genes, 1 drug (DrugBank) and 10 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
32 | Chemokine signaling pathway 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: CCL2 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
33 | Cholinergic synapse 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
34 | Circadian entrainment 2 genes, 2 drugs (DrugBank) and 4 diseases shown |
2件: CACNA1C, CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
35 | Cortisol synthesis and secretion 5 genes, 6 drugs (DrugBank) and 24 diseases shown |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
36 | Cushing syndrome 5 genes, 6 drugs (DrugBank) and 24 diseases shown |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
37 | Cytokine-cytokine receptor interaction 6 genes, 1 drug (DrugBank) and 10 diseases shown |
6件: CCL2, IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
38 | Cytosolic DNA-sensing pathway 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
39 | Dilated cardiomyopathy (DCM) 6 genes, 5 drugs (DrugBank) and 20 diseases shown |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
D00601 |
Metoprolol |
7件: 17, 57, 58, 66, 113, 193, 226 |
D02358 |
D05011 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
40 | Dopaminergic synapse 5 genes, 3 drugs (DrugBank) and 47 diseases shown |
2件: CACNA1C, CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
3件: PPP3CA, PPP3CB, PPP3CC |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
41 | EGFR tyrosine kinase inhibitor resistance 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
42 | Epstein-Barr virus infection 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
43 | Fatty acid degradation 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: CPT1A, CPT1B, CPT1C, CPT2 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
44 | Fatty acid metabolism 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: CPT1A, CPT1B, CPT1C, CPT2 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
45 | Fc epsilon RI signaling pathway 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
46 | Fluid shear stress and atherosclerosis 4 genes, 1 drug (DrugBank) and 10 diseases shown |
4件: CCL2, IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
47 | FoxO signaling pathway 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
48 | GABAergic synapse 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
49 | Gap junction 1 gene, 2 drugs (DrugBank) and 8 diseases shown |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
D00601 |
Metoprolol |
7件: 17, 57, 58, 66, 113, 193, 226 |
D02358 |
D05011 |
50 | Glucagon signaling pathway 8 genes, 2 drugs (DrugBank) and 45 diseases shown |
3件: CPT1A, CPT1B, CPT1C |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
51 | Glutamatergic synapse 7 genes, 3 drugs (DrugBank) and 47 diseases shown |
2件: CACNA1C, CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
52 | GnRH secretion 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
53 | GnRH signaling pathway 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
54 | Graft-versus-host disease 4 genes, 1 drug (DrugBank) and 10 diseases shown |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
55 | Growth hormone synthesis, secretion and action 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
56 | Hematopoietic cell lineage 5 genes, 2 drugs (DrugBank) and 10 diseases shown |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: MME |
D10225 |
Sacubitril |
1件: 58 |
57 | Hepatitis B 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
58 | Hepatitis C 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
59 | Herpes simplex virus 1 infection 4 genes, 1 drug (DrugBank) and 10 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
60 | HIF-1 signaling pathway 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
61 | Human cytomegalovirus infection 9 genes, 2 drugs (DrugBank) and 48 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
62 | Human immunodeficiency virus 1 infection 6 genes, 2 drugs (DrugBank) and 48 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
63 | Human papillomavirus infection 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
64 | Human T-cell leukemia virus 1 infection 7 genes, 2 drugs (DrugBank) and 48 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
65 | Hypertrophic cardiomyopathy (HCM) 6 genes, 3 drugs (DrugBank) and 13 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
66 | IL-17 signaling pathway 4 genes, 1 drug (DrugBank) and 10 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
67 | Inflammatory bowel disease (IBD) 5 genes, 1 drug (DrugBank) and 10 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
68 | Inflammatory mediator regulation of TRP channels 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: IL1B |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
69 | Influenza A 5 genes, 1 drug (DrugBank) and 10 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
70 | Insulin resistance 4 genes, 2 drugs (DrugBank) and 11 diseases shown |
2件: CPT1A, CPT1B |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
71 | Insulin secretion 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
72 | Intestinal immune network for IgA production 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
73 | JAK-STAT signaling pathway 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
74 | Kaposi sarcoma-associated herpesvirus infection 6 genes, 2 drugs (DrugBank) and 48 diseases shown |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
75 | Legionellosis 3 genes, 1 drug (DrugBank) and 10 diseases shown |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
76 | Leishmaniasis 4 genes, 1 drug (DrugBank) and 10 diseases shown |
4件: IL10, IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
77 | Long-term potentiation 6 genes, 3 drugs (DrugBank) and 47 diseases shown |
1件: CACNA1C |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
78 | Malaria 5 genes, 1 drug (DrugBank) and 10 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
79 | MAPK signaling pathway 12 genes, 4 drugs (DrugBank) and 51 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
80 | Measles 3 genes, 1 drug (DrugBank) and 10 diseases shown |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
81 | Metabolic pathways 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
82 | Morphine addiction 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: ADORA1 |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
83 | mTOR signaling pathway 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
84 | Natural killer cell mediated cytotoxicity 6 genes, 2 drugs (DrugBank) and 48 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
85 | Necroptosis 3 genes, 1 drug (DrugBank) and 10 diseases shown |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
86 | Neuroactive ligand-receptor interaction 9 genes, 9 drugs (DrugBank) and 26 diseases shown |
4件: ADORA1, ADORA2A, ADORA2B, ADORA3 |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
1件: ADORA2A |
D05711 |
Regadenoson |
1件: 58 |
3件: ADRA1A, ADRA1B, ADRA1D |
D01307 |
Midodrine |
3件: 6, 17, 58 |
D08220 |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
D00601 |
Metoprolol |
7件: 17, 57, 58, 66, 113, 193, 226 |
D02358 |
D05011 |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
87 | NF-kappa B signaling pathway 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
88 | NOD-like receptor signaling pathway 4 genes, 1 drug (DrugBank) and 10 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
89 | Non-alcoholic fatty liver disease (NAFLD) 4 genes, 1 drug (DrugBank) and 10 diseases shown |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
90 | Oocyte meiosis 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
91 | Osteoclast differentiation 8 genes, 2 drugs (DrugBank) and 48 diseases shown |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
92 | Oxytocin signaling pathway 9 genes, 3 drugs (DrugBank) and 47 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
93 | Parkinson disease 1 gene, 2 drugs (DrugBank) and 5 diseases shown |
1件: ADORA2A |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
D05711 |
Regadenoson |
1件: 58 |
94 | Pathogenic Escherichia coli infection 3 genes, 1 drug (DrugBank) and 10 diseases shown |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
95 | Pathways in cancer 2 genes, 5 drugs (DrugBank) and 26 diseases shown |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
96 | PD-L1 expression and PD-1 checkpoint pathway in cancer 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
97 | Pertussis 5 genes, 1 drug (DrugBank) and 10 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
98 | Phospholipase D signaling pathway 1 gene, 4 drugs (DrugBank) and 21 diseases shown |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
99 | PI3K-Akt signaling pathway 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
100 | PPAR signaling pathway 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: CPT1A, CPT1B, CPT1C, CPT2 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
101 | Prion diseases 3 genes, 1 drug (DrugBank) and 10 diseases shown |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
102 | Protein digestion and absorption 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: MME |
D10225 |
Sacubitril |
1件: 58 |
103 | Proteoglycans in cancer 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
104 | Rap1 signaling pathway 2 genes, 2 drugs (DrugBank) and 5 diseases shown |
1件: ADORA2A |
D05711 |
Regadenoson |
1件: 58 |
2件: ADORA2A, ADORA2B |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
105 | Regulation of lipolysis in adipocytes 2 genes, 3 drugs (DrugBank) and 12 diseases shown |
1件: ADORA1 |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
D00601 |
Metoprolol |
7件: 17, 57, 58, 66, 113, 193, 226 |
D02358 |
D05011 |
106 | Renin secretion 12 genes, 10 drugs (DrugBank) and 62 diseases shown |
1件: ADORA1 |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
D00601 |
Metoprolol |
7件: 17, 57, 58, 66, 113, 193, 226 |
D02358 |
D05011 |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
107 | Renin-angiotensin system 2 genes, 5 drugs (DrugBank) and 21 diseases shown |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
1件: MME |
D10225 |
Sacubitril |
1件: 58 |
108 | Retrograde endocannabinoid signaling 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
109 | Rheumatoid arthritis 5 genes, 1 drug (DrugBank) and 10 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
110 | RIG-I-like receptor signaling pathway 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
111 | Salivary secretion 4 genes, 3 drugs (DrugBank) and 9 diseases shown |
3件: ADRA1A, ADRA1B, ADRA1D |
D01307 |
Midodrine |
3件: 6, 17, 58 |
D08220 |
1件: ADRB1 |
D00632 |
Dobutamine |
3件: 57, 58, 215 |
D03879 |
D03880 |
D03881 |
D00601 |
Metoprolol |
7件: 17, 57, 58, 66, 113, 193, 226 |
D02358 |
D05011 |
112 | Salmonella infection 3 genes, 1 drug (DrugBank) and 10 diseases shown |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
113 | Serotonergic synapse 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
114 | Shigellosis 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
115 | Sphingolipid signaling pathway 3 genes, 2 drugs (DrugBank) and 13 diseases shown |
2件: ADORA1, ADORA3 |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
116 | Staphylococcus aureus infection 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: IL10 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
117 | Systemic lupus erythematosus 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
118 | T cell receptor signaling pathway 7 genes, 2 drugs (DrugBank) and 48 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
119 | Taste transduction 1 gene, 2 drugs (DrugBank) and 4 diseases shown |
1件: CACNA1C |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
120 | Terpenoid backbone biosynthesis 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
121 | TGF-beta signaling pathway 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
122 | Th1 and Th2 cell differentiation 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
123 | Th17 cell differentiation 7 genes, 2 drugs (DrugBank) and 48 diseases shown |
2件: IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
124 | Thermogenesis 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: CPT1A, CPT1B, CPT1C, CPT2 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
125 | Tight junction 1 gene, 2 drugs (DrugBank) and 4 diseases shown |
1件: CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
126 | TNF signaling pathway 4 genes, 1 drug (DrugBank) and 10 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
127 | Toll-like receptor signaling pathway 3 genes, 1 drug (DrugBank) and 10 diseases shown |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
128 | Toxoplasmosis 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
129 | Transcriptional misregulation in cancer 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
130 | Tuberculosis 10 genes, 2 drugs (DrugBank) and 48 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
131 | Type I diabetes mellitus 3 genes, 1 drug (DrugBank) and 10 diseases shown |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
132 | Type II diabetes mellitus 3 genes, 3 drugs (DrugBank) and 13 diseases shown |
2件: CACNA1C, CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
1件: TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
133 | Vascular smooth muscle contraction 10 genes, 9 drugs (DrugBank) and 27 diseases shown |
1件: ADORA2A |
D05711 |
Regadenoson |
1件: 58 |
2件: ADORA2A, ADORA2B |
D00045 |
Adenosine |
5件: 13, 46, 53, 58, 65 |
3件: ADRA1A, ADRA1B, ADRA1D |
D01307 |
Midodrine |
3件: 6, 17, 58 |
D08220 |
1件: AGTR1 |
D00522 |
Candesartan |
2件: 58, 67 |
D00522 |
Candesartan cilexetil |
2件: 58, 67 |
D00626 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D05442 |
Perhexiline |
2件: 58, 272 |
D08340 |
134 | VEGF signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
135 | Viral protein interaction with cytokine and cytokine receptor 4 genes, 1 drug (DrugBank) and 10 diseases shown |
4件: CCL2, IL10, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
136 | Wnt signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
137 | Yersinia infection 5 genes, 1 drug (DrugBank) and 10 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |