No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Acute myeloid leukemia 3 genes, 4 drugs (DrugBank) and 40 diseases shown |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: RARA |
D01418 |
Tamibarotene |
2件: 26, 96 |
2 | Adherens junction 2 genes, 2 drugs (DrugBank) and 7 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
3 | Adipocytokine signaling pathway 3 genes, 9 drugs (DrugBank) and 68 diseases shown |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
4 | Adrenergic signaling in cardiomyocytes 11 genes, 4 drugs (DrugBank) and 29 diseases shown |
5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
1件: SCN5A |
D01450 |
Bupivacaine |
7件: 46, 53, 70, 96, 168, 226, 298 |
D07552 |
5 | African trypanosomiasis 3 genes, 7 drugs (DrugBank) and 45 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
6 | AGE-RAGE signaling pathway in diabetic complications 3 genes, 8 drugs (DrugBank) and 54 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
7 | Alcoholism 18 genes, 4 drugs (DrugBank) and 10 diseases shown |
1件: ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
11件: HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 |
D06320 |
Vorinostat |
2件: 19, 96 |
1件: SLC6A3 |
D00817 |
Bupropion |
2件: 8, 96 |
D07591 |
D07938 |
8 | Aldosterone synthesis and secretion 6 genes, 3 drugs (DrugBank) and 23 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
1件: PDE2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
9 | Aldosterone-regulated sodium reabsorption 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
10 | Allograft rejection 25 genes, 9 drugs (DrugBank) and 52 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
11 | Alzheimer disease 15 genes, 9 drugs (DrugBank) and 64 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
12 | Amoebiasis 3 genes, 7 drugs (DrugBank) and 45 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
13 | Amphetamine addiction 15 genes, 5 drugs (DrugBank) and 38 diseases shown |
2件: CACNA1C, CACNA1D |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
2件: HDAC1, HDAC2 |
D06320 |
Vorinostat |
2件: 19, 96 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: SLC6A3 |
D00817 |
Bupropion |
2件: 8, 96 |
D07591 |
D07938 |
14 | AMPK signaling pathway 6 genes, 9 drugs (DrugBank) and 59 diseases shown |
1件: ADRA1A |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00893 |
Pravastatin |
9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 |
D08410 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
15 | Amyotrophic lateral sclerosis (ALS) 11 genes, 8 drugs (DrugBank) and 61 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
16 | Antifolate resistance 3 genes, 7 drugs (DrugBank) and 55 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
17 | Antigen processing and presentation 21 genes, 7 drugs (DrugBank) and 45 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
18 | Apelin signaling pathway 5 genes, 5 drugs (DrugBank) and 48 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
2件: HDAC4, HDAC5 |
D06320 |
Vorinostat |
2件: 19, 96 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
19 | Apoptosis 1 gene, 6 drugs (DrugBank) and 43 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
20 | Arachidonic acid metabolism 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
21 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) 6 genes, 4 drugs (DrugBank) and 10 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
2件: ITGA4, ITGB7 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: ITGB7 |
D09901 |
Etrolizumab |
2件: 96, 97 |
22 | Asthma 15 genes, 7 drugs (DrugBank) and 45 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
23 | Autoimmune thyroid disease 23 genes, 3 drugs (DrugBank) and 26 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: CTLA4 |
D06657 |
Tremelimumab |
2件: 65, 96 |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
24 | Autophagy - animal 2 genes, 3 drugs (DrugBank) and 41 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
25 | Autophagy - other 1 gene, 2 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
26 | Axon guidance 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
27 | B cell receptor signaling pathway 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
28 | Bile secretion 2 genes, 5 drugs (DrugBank) and 28 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00893 |
Pravastatin |
9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 |
D08410 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
1件: NR1H4 |
D00163 |
Chenodeoxycholic acid |
4件: 20, 96, 234, 263 |
D00734 |
Ursodeoxycholic acid |
12件: 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 299 |
29 | Breast cancer 6 genes, 6 drugs (DrugBank) and 50 diseases shown |
2件: ESR1, ESR2 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
30 | C-type lectin receptor signaling pathway 10 genes, 12 drugs (DrugBank) and 62 diseases shown |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL23A |
D10438 |
Guselkumab |
3件: 37, 96, 97 |
D11123 |
Mirikizumab |
2件: 96, 97 |
D11052 |
Risankizumab |
4件: 37, 96, 97, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
31 | Caffeine metabolism 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: XDH |
D00224 |
Allopurinol |
6件: 6, 46, 57, 66, 96, 97 |
32 | Calcium signaling pathway 24 genes, 9 drugs (DrugBank) and 47 diseases shown |
2件: ADORA2A, PDE1B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
4件: GRIN1, GRIN2A, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: HRH1 |
D00480 |
Promethazine |
1件: 96 |
D00494 |
D01242 |
D03290 |
1件: HTR4 |
D08236 |
Mosapride |
1件: 96 |
D09205 |
Prucalopride |
3件: 13, 51, 96 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
33 | cAMP signaling pathway 21 genes, 7 drugs (DrugBank) and 25 diseases shown |
8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
2件: ADRB1, ADRB2 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: HTR4 |
D08236 |
Mosapride |
1件: 96 |
D09205 |
Prucalopride |
3件: 13, 51, 96 |
1件: SSTR2 |
D00442 |
Octreotide |
8件: 67, 75, 84, 85, 89, 96, 193, 227 |
D06495 |
34 | Carbohydrate digestion and absorption 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: CACNA1D |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
35 | Cardiac muscle contraction 4 genes, 1 drug (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
36 | Cell adhesion molecules (CAMs) 27 genes, 8 drugs (DrugBank) and 33 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: CTLA4 |
D06657 |
Tremelimumab |
2件: 65, 96 |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
2件: ITGA4, ITGB7 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: ITGB7 |
D09901 |
Etrolizumab |
2件: 96, 97 |
1件: PDCD1 |
D10316 |
Nivolumab |
10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 |
37 | Cell cycle 2 genes, 1 drug (DrugBank) and 2 diseases shown |
2件: HDAC1, HDAC2 |
D06320 |
Vorinostat |
2件: 19, 96 |
38 | Cellular senescence 13 genes, 5 drugs (DrugBank) and 53 diseases shown |
1件: CACNA1D |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
39 | Central carbon metabolism in cancer 2 genes, 3 drugs (DrugBank) and 39 diseases shown |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
40 | cGMP-PKG signaling pathway 26 genes, 8 drugs (DrugBank) and 59 diseases shown |
5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: OPRD1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
41 | Chagas disease (American trypanosomiasis) 6 genes, 9 drugs (DrugBank) and 46 diseases shown |
3件: CD3D, CD3E, CD3G |
D05092 |
Muromonab |
3件: 60, 96, 97 |
D06314 |
Visilizumab |
2件: 96, 97 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
42 | Chemical carcinogenesis 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
43 | Chemokine signaling pathway 2 genes, 1 drug (DrugBank) and 9 diseases shown |
2件: JAK2, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
44 | Choline metabolism in cancer 1 gene, 2 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
45 | Cholinergic synapse 5 genes, 2 drugs (DrugBank) and 12 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
46 | Chronic myeloid leukemia 2 genes, 1 drug (DrugBank) and 2 diseases shown |
2件: HDAC1, HDAC2 |
D06320 |
Vorinostat |
2件: 19, 96 |
47 | Circadian entrainment 7 genes, 2 drugs (DrugBank) and 12 diseases shown |
2件: CACNA1C, CACNA1D |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
48 | Cocaine addiction 6 genes, 2 drugs (DrugBank) and 9 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: SLC6A3 |
D00817 |
Bupropion |
2件: 8, 96 |
D07591 |
D07938 |
49 | Collecting duct acid secretion 2 genes, 1 drug (DrugBank) and 15 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
50 | Colorectal cancer 1 gene, 2 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
51 | Complement and coagulation cascades 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: F10 |
D03213 |
Apixaban |
2件: 96, 97 |
52 | Cortisol synthesis and secretion 5 genes, 2 drugs (DrugBank) and 20 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
53 | Cushing syndrome 5 genes, 2 drugs (DrugBank) and 20 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
54 | Cytokine-cytokine receptor interaction 12 genes, 19 drugs (DrugBank) and 73 diseases shown |
1件: CSF2RA |
D05803 |
Sargramostim |
6件: 6, 28, 60, 62, 96, 229 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EPOR |
D03231 |
Erythropoietin |
9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 |
1件: GHR |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: IL11RA |
D05266 |
Oprelvekin |
2件: 96, 288 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL23A |
D10438 |
Guselkumab |
3件: 37, 96, 97 |
D11123 |
Mirikizumab |
2件: 96, 97 |
D11052 |
Risankizumab |
4件: 37, 96, 97, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
55 | Dilated cardiomyopathy (DCM) 8 genes, 11 drugs (DrugBank) and 55 diseases shown |
1件: ADRB1 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
2件: ITGA4, ITGB7 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: ITGB7 |
D09901 |
Etrolizumab |
2件: 96, 97 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
56 | DNA replication 2 genes, 1 drug (DrugBank) and 9 diseases shown |
2件: POLA1, POLA2 |
D03546 |
Clofarabine |
9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 |
57 | Dopaminergic synapse 9 genes, 5 drugs (DrugBank) and 40 diseases shown |
2件: CACNA1C, CACNA1D |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
2件: GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
3件: PPP3CA, PPP3CB, PPP3CC |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: SCN1A |
D01450 |
Bupivacaine |
7件: 46, 53, 70, 96, 168, 226, 298 |
D07552 |
1件: SLC6A3 |
D00817 |
Bupropion |
2件: 8, 96 |
D07591 |
D07938 |
58 | Drug metabolism - other enzymes 5 genes, 6 drugs (DrugBank) and 43 diseases shown |
1件: HPRT1 |
D00161 |
Mercaptopurine |
5件: 86, 94, 96, 97, 164 |
D04931 |
2件: IMPDH1, IMPDH2 |
D00752 |
Mycophenolate mofetil |
32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
D05094 |
D05095 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
1件: RRM1 |
D03546 |
Clofarabine |
9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
1件: XDH |
D00224 |
Allopurinol |
6件: 6, 46, 57, 66, 96, 97 |
59 | ECM-receptor interaction 2 genes, 3 drugs (DrugBank) and 7 diseases shown |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
2件: ITGA4, ITGB7 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: ITGB7 |
D09901 |
Etrolizumab |
2件: 96, 97 |
60 | EGFR tyrosine kinase inhibitor resistance 4 genes, 6 drugs (DrugBank) and 48 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
61 | Endocrine and other factor-regulated calcium reabsorption 2 genes, 5 drugs (DrugBank) and 26 diseases shown |
1件: ESR1 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
1件: VDR |
D01518 |
Alfacalcidol |
6件: 41, 46, 49, 50, 96, 235 |
D00129 |
Calcitriol |
8件: 37, 46, 49, 66, 96, 158, 235, 326 |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
62 | Endocrine resistance 4 genes, 4 drugs (DrugBank) and 44 diseases shown |
2件: ESR1, ESR2 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
63 | Endocytosis 7 genes, 2 drugs (DrugBank) and 9 diseases shown |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
64 | Epstein-Barr virus infection 32 genes, 16 drugs (DrugBank) and 51 diseases shown |
3件: CD3D, CD3E, CD3G |
D05092 |
Muromonab |
3件: 60, 96, 97 |
D06314 |
Visilizumab |
2件: 96, 97 |
2件: HDAC1, HDAC2 |
D06320 |
Vorinostat |
2件: 19, 96 |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
3件: JAK1, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
65 | ErbB signaling pathway 1 gene, 2 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
66 | Estrogen signaling pathway 4 genes, 3 drugs (DrugBank) and 17 diseases shown |
2件: ESR1, ESR2 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
1件: OPRM1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
1件: RARA |
D01418 |
Tamibarotene |
2件: 26, 96 |
67 | Fc epsilon RI signaling pathway 1 gene, 6 drugs (DrugBank) and 43 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
68 | Fluid shear stress and atherosclerosis 2 genes, 7 drugs (DrugBank) and 48 diseases shown |
1件: NQO1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
69 | Focal adhesion 3 genes, 4 drugs (DrugBank) and 12 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
2件: ITGA4, ITGB7 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: ITGB7 |
D09901 |
Etrolizumab |
2件: 96, 97 |
70 | Folate biosynthesis 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
71 | FoxO signaling pathway 4 genes, 3 drugs (DrugBank) and 9 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
2件: S1PR1, S1PR4 |
D10968 |
Ozanimod |
3件: 13, 96, 97 |
72 | GABAergic synapse 20 genes, 2 drugs (DrugBank) and 13 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
73 | Gap junction 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: ADRB1 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
74 | Gastric acid secretion 3 genes, 2 drugs (DrugBank) and 21 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
1件: SSTR2 |
D00442 |
Octreotide |
8件: 67, 75, 84, 85, 89, 96, 193, 227 |
D06495 |
75 | Gastric cancer 1 gene, 2 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
76 | Glioma 2 genes, 3 drugs (DrugBank) and 41 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
77 | Glucagon signaling pathway 6 genes, 2 drugs (DrugBank) and 32 diseases shown |
1件: PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
78 | Glutamatergic synapse 12 genes, 3 drugs (DrugBank) and 37 diseases shown |
2件: CACNA1C, CACNA1D |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
79 | Glutathione metabolism 1 gene, 2 drugs (DrugBank) and 21 diseases shown |
1件: RRM1 |
D03546 |
Clofarabine |
9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
80 | GnRH secretion 5 genes, 2 drugs (DrugBank) and 9 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
1件: ESR2 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
81 | GnRH signaling pathway 4 genes, 1 drug (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
82 | Graft-versus-host disease 23 genes, 8 drugs (DrugBank) and 52 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
83 | Growth hormone synthesis, secretion and action 8 genes, 7 drugs (DrugBank) and 61 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
1件: GHR |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: SSTR2 |
D00442 |
Octreotide |
8件: 67, 75, 84, 85, 89, 96, 193, 227 |
D06495 |
84 | Hematopoietic cell lineage 25 genes, 17 drugs (DrugBank) and 75 diseases shown |
3件: CD3D, CD3E, CD3G |
D05092 |
Muromonab |
3件: 60, 96, 97 |
D06314 |
Visilizumab |
2件: 96, 97 |
1件: CSF2RA |
D05803 |
Sargramostim |
6件: 6, 28, 60, 62, 96, 229 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EPOR |
D03231 |
Erythropoietin |
9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: IL11RA |
D05266 |
Oprelvekin |
2件: 96, 288 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
1件: MS4A1 |
D02994 |
Rituximab |
42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
85 | Hepatitis B 6 genes, 11 drugs (DrugBank) and 47 diseases shown |
1件: IFNAR1 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
86 | Hepatitis C 5 genes, 11 drugs (DrugBank) and 47 diseases shown |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
87 | Hepatocellular carcinoma 3 genes, 4 drugs (DrugBank) and 45 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NQO1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
88 | Herpes simplex virus 1 infection 29 genes, 15 drugs (DrugBank) and 72 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
89 | HIF-1 signaling pathway 3 genes, 4 drugs (DrugBank) and 42 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
90 | Hippo signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: SMAD7 |
D10956 |
Mongersen |
2件: 96, 97 |
91 | Human cytomegalovirus infection 15 genes, 14 drugs (DrugBank) and 76 diseases shown |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
92 | Human immunodeficiency virus 1 infection 16 genes, 12 drugs (DrugBank) and 72 diseases shown |
3件: CD3D, CD3E, CD3G |
D05092 |
Muromonab |
3件: 60, 96, 97 |
D06314 |
Visilizumab |
2件: 96, 97 |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
93 | Human papillomavirus infection 17 genes, 19 drugs (DrugBank) and 74 diseases shown |
2件: HDAC1, HDAC2 |
D06320 |
Vorinostat |
2件: 19, 96 |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
2件: ITGA4, ITGB7 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: ITGB7 |
D09901 |
Etrolizumab |
2件: 96, 97 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
94 | Human T-cell leukemia virus 1 infection 33 genes, 16 drugs (DrugBank) and 63 diseases shown |
3件: CD3D, CD3E, CD3G |
D05092 |
Muromonab |
3件: 60, 96, 97 |
D06314 |
Visilizumab |
2件: 96, 97 |
1件: FDPS |
D00942 |
Risedronic acid |
7件: 46, 66, 93, 95, 96, 113, 274 |
D03234 |
D08484 |
D01968 |
Zoledronic acid |
11件: 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
95 | Huntington disease 5 genes, 3 drugs (DrugBank) and 21 diseases shown |
2件: GRIN1, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
2件: HDAC1, HDAC2 |
D06320 |
Vorinostat |
2件: 19, 96 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
96 | Hypertrophic cardiomyopathy (HCM) 7 genes, 10 drugs (DrugBank) and 50 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
2件: ITGA4, ITGB7 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: ITGB7 |
D09901 |
Etrolizumab |
2件: 96, 97 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
97 | IL-17 signaling pathway 2 genes, 7 drugs (DrugBank) and 47 diseases shown |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
98 | Inflammatory bowel disease (IBD) 18 genes, 11 drugs (DrugBank) and 46 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL23A |
D10438 |
Guselkumab |
3件: 37, 96, 97 |
D11123 |
Mirikizumab |
2件: 96, 97 |
D11052 |
Risankizumab |
4件: 37, 96, 97, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
99 | Inflammatory mediator regulation of TRP channels 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: HRH1 |
D00480 |
Promethazine |
1件: 96 |
D00494 |
D01242 |
D03290 |
100 | Influenza A 23 genes, 15 drugs (DrugBank) and 55 diseases shown |
1件: FDPS |
D00942 |
Risedronic acid |
7件: 46, 66, 93, 95, 96, 113, 274 |
D03234 |
D08484 |
D01968 |
Zoledronic acid |
11件: 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
101 | Insulin resistance 3 genes, 9 drugs (DrugBank) and 68 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
102 | Insulin secretion 4 genes, 1 drug (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
103 | Insulin signaling pathway 3 genes, 4 drugs (DrugBank) and 41 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
104 | Intestinal immune network for IgA production 18 genes, 5 drugs (DrugBank) and 29 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
2件: ITGA4, ITGB7 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: ITGB7 |
D09901 |
Etrolizumab |
2件: 96, 97 |
105 | JAK-STAT signaling pathway 15 genes, 17 drugs (DrugBank) and 81 diseases shown |
1件: CSF2RA |
D05803 |
Sargramostim |
6件: 6, 28, 60, 62, 96, 229 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EPOR |
D03231 |
Erythropoietin |
9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 |
1件: GHR |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: IL11RA |
D05266 |
Oprelvekin |
2件: 96, 288 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL23A |
D10438 |
Guselkumab |
3件: 37, 96, 97 |
D11123 |
Mirikizumab |
2件: 96, 97 |
D11052 |
Risankizumab |
4件: 37, 96, 97, 271 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
106 | Kaposi sarcoma-associated herpesvirus infection 19 genes, 11 drugs (DrugBank) and 67 diseases shown |
1件: CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
107 | Legionellosis 3 genes, 7 drugs (DrugBank) and 45 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
108 | Leishmaniasis 21 genes, 14 drugs (DrugBank) and 54 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
109 | Leukocyte transendothelial migration 2 genes, 3 drugs (DrugBank) and 13 diseases shown |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
110 | Long-term depression 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
111 | Long-term potentiation 11 genes, 3 drugs (DrugBank) and 37 diseases shown |
1件: CACNA1C |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
112 | Longevity regulating pathway 4 genes, 5 drugs (DrugBank) and 47 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
113 | Longevity regulating pathway - multiple species 5 genes, 5 drugs (DrugBank) and 43 diseases shown |
2件: HDAC1, HDAC2 |
D06320 |
Vorinostat |
2件: 19, 96 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
114 | Malaria 3 genes, 8 drugs (DrugBank) and 47 diseases shown |
1件: IL12A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
115 | MAPK signaling pathway 13 genes, 11 drugs (DrugBank) and 66 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
116 | Measles 10 genes, 8 drugs (DrugBank) and 24 diseases shown |
3件: CD3D, CD3E, CD3G |
D05092 |
Muromonab |
3件: 60, 96, 97 |
D06314 |
Visilizumab |
2件: 96, 97 |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
3件: JAK1, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
117 | Melanogenesis 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
118 | Melanoma 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
119 | Metabolic pathways 23 genes, 17 drugs (DrugBank) and 80 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
1件: FDPS |
D00942 |
Risedronic acid |
7件: 46, 66, 93, 95, 96, 113, 274 |
D03234 |
D08484 |
D01968 |
Zoledronic acid |
11件: 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00893 |
Pravastatin |
9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 |
D08410 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
1件: HPRT1 |
D00161 |
Mercaptopurine |
5件: 86, 94, 96, 97, 164 |
D04931 |
2件: IMPDH1, IMPDH2 |
D00752 |
Mycophenolate mofetil |
32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
D05094 |
D05095 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
2件: NQO1, VKORC1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
1件: RRM1 |
D03546 |
Clofarabine |
9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
1件: XDH |
D00224 |
Allopurinol |
6件: 6, 46, 57, 66, 96, 97 |
120 | MicroRNAs in cancer 6 genes, 4 drugs (DrugBank) and 42 diseases shown |
4件: HDAC1, HDAC2, HDAC4, HDAC5 |
D06320 |
Vorinostat |
2件: 19, 96 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
121 | Mineral absorption 1 gene, 4 drugs (DrugBank) and 23 diseases shown |
1件: VDR |
D01518 |
Alfacalcidol |
6件: 41, 46, 49, 50, 96, 235 |
D00129 |
Calcitriol |
8件: 37, 46, 49, 66, 96, 158, 235, 326 |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
122 | Morphine addiction 26 genes, 3 drugs (DrugBank) and 18 diseases shown |
9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
1件: OPRM1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
123 | mTOR signaling pathway 4 genes, 10 drugs (DrugBank) and 72 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
124 | Natural killer cell mediated cytotoxicity 14 genes, 11 drugs (DrugBank) and 60 diseases shown |
5件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
125 | Necroptosis 7 genes, 11 drugs (DrugBank) and 47 diseases shown |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
126 | Neuroactive ligand-receptor interaction 49 genes, 22 drugs (DrugBank) and 95 diseases shown |
2件: ADORA1, ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
2件: CNR1, CNR2 |
D10915 |
Cannabidiol |
14件: 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
1件: GHR |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
1件: GLP2R |
D06053 |
Teduglutide |
1件: 96 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: HRH1 |
D00480 |
Promethazine |
1件: 96 |
D00494 |
D01242 |
D03290 |
1件: HTR4 |
D08236 |
Mosapride |
1件: 96 |
D09205 |
Prucalopride |
3件: 13, 51, 96 |
1件: NR3C1 |
D00244 |
Betamethasone |
6件: 2, 46, 65, 90, 96, 235 |
D00972 |
D01357 |
D01402 |
D01637 |
D02032 |
D02286 |
D00246 |
Budesonide |
10件: 66, 85, 93, 94, 95, 96, 97, 98, 228, 299 |
D00292 |
Dexamethasone |
20件: 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299 |
D00975 |
D01510 |
D01615 |
D01632 |
D01948 |
D02174 |
D02591 |
D02592 |
D00407 |
Methylprednisolone |
36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 |
D00751 |
D00979 |
D05000 |
D05001 |
D05002 |
D00472 |
Prednisolone |
38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
D00980 |
D00981 |
D00982 |
D01239 |
D01998 |
D02156 |
D03301 |
D00473 |
Prednisone |
44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
D00385 |
Triamcinolone |
18件: 6, 10, 13, 35, 40, 41, 42, 43, 44, 45, 46, 56, 70, 90, 96, 97, 226, 298 |
D00983 |
D00984 |
D00985 |
D06216 |
3件: OPRD1, OPRK1, OPRM1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
5件: S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 |
D10968 |
Ozanimod |
3件: 13, 96, 97 |
1件: SSTR2 |
D00442 |
Octreotide |
8件: 67, 75, 84, 85, 89, 96, 193, 227 |
D06495 |
127 | NF-kappa B signaling pathway 3 genes, 8 drugs (DrugBank) and 50 diseases shown |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
128 | Nicotine addiction 21 genes, 2 drugs (DrugBank) and 13 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
129 | NOD-like receptor signaling pathway 5 genes, 11 drugs (DrugBank) and 47 diseases shown |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
130 | Non-alcoholic fatty liver disease (NAFLD) 2 genes, 7 drugs (DrugBank) and 44 diseases shown |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
131 | Non-small cell lung cancer 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
132 | Notch signaling pathway 2 genes, 1 drug (DrugBank) and 2 diseases shown |
2件: HDAC1, HDAC2 |
D06320 |
Vorinostat |
2件: 19, 96 |
133 | Olfactory transduction 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: PDE1B, PDE2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
134 | One carbon pool by folate 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
135 | Oocyte meiosis 7 genes, 3 drugs (DrugBank) and 34 diseases shown |
1件: AR |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
136 | Osteoclast differentiation 12 genes, 14 drugs (DrugBank) and 69 diseases shown |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
137 | Ovarian steroidogenesis 3 genes, 3 drugs (DrugBank) and 15 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
138 | Oxidative phosphorylation 2 genes, 1 drug (DrugBank) and 15 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
139 | Oxytocin signaling pathway 10 genes, 3 drugs (DrugBank) and 39 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
140 | Pancreatic cancer 2 genes, 5 drugs (DrugBank) and 44 diseases shown |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
141 | Parathyroid hormone synthesis, secretion and action 6 genes, 6 drugs (DrugBank) and 28 diseases shown |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
1件: VDR |
D01518 |
Alfacalcidol |
6件: 41, 46, 49, 50, 96, 235 |
D00129 |
Calcitriol |
8件: 37, 46, 49, 66, 96, 158, 235, 326 |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
142 | Parkinson disease 2 genes, 2 drugs (DrugBank) and 7 diseases shown |
1件: ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
1件: SLC6A3 |
D00817 |
Bupropion |
2件: 8, 96 |
D07591 |
D07938 |
143 | Pathogenic Escherichia coli infection 1 gene, 6 drugs (DrugBank) and 43 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
144 | Pathways in cancer 24 genes, 23 drugs (DrugBank) and 84 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
3件: AR, ESR1, ESR2 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
1件: CSF2RA |
D05803 |
Sargramostim |
6件: 6, 28, 60, 62, 96, 229 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EPOR |
D03231 |
Erythropoietin |
9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 |
2件: HDAC1, HDAC2 |
D06320 |
Vorinostat |
2件: 19, 96 |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL23A |
D10438 |
Guselkumab |
3件: 37, 96, 97 |
D11123 |
Mirikizumab |
2件: 96, 97 |
D11052 |
Risankizumab |
4件: 37, 96, 97, 271 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
3件: JAK1, JAK2, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: NQO1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
1件: RARA |
D01418 |
Tamibarotene |
2件: 26, 96 |
145 | PD-L1 expression and PD-1 checkpoint pathway in cancer 12 genes, 9 drugs (DrugBank) and 54 diseases shown |
3件: CD3D, CD3E, CD3G |
D05092 |
Muromonab |
3件: 60, 96, 97 |
D06314 |
Visilizumab |
2件: 96, 97 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDCD1 |
D10316 |
Nivolumab |
10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
146 | Peroxisome 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: XDH |
D00224 |
Allopurinol |
6件: 6, 46, 57, 66, 96, 97 |
147 | Pertussis 4 genes, 10 drugs (DrugBank) and 45 diseases shown |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL23A |
D10438 |
Guselkumab |
3件: 37, 96, 97 |
D11123 |
Mirikizumab |
2件: 96, 97 |
D11052 |
Risankizumab |
4件: 37, 96, 97, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
148 | Phagosome 20 genes, 1 drug (DrugBank) and 4 diseases shown |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
149 | Phospholipase D signaling pathway 4 genes, 5 drugs (DrugBank) and 49 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
150 | PI3K-Akt signaling pathway 14 genes, 16 drugs (DrugBank) and 77 diseases shown |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EPOR |
D03231 |
Erythropoietin |
9件: 2, 6, 13, 22, 46, 47, 70, 95, 96 |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
2件: GHR, IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
2件: ITGA4, ITGB7 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: ITGB7 |
D09901 |
Etrolizumab |
2件: 96, 97 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
3件: JAK1, JAK2, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
151 | PPAR signaling pathway 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
152 | Primary immunodeficiency 3 genes, 3 drugs (DrugBank) and 10 diseases shown |
2件: CD3D, CD3E |
D05092 |
Muromonab |
3件: 60, 96, 97 |
D06314 |
Visilizumab |
2件: 96, 97 |
1件: JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
153 | Progesterone-mediated oocyte maturation 2 genes, 2 drugs (DrugBank) and 10 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
154 | Prolactin signaling pathway 4 genes, 3 drugs (DrugBank) and 17 diseases shown |
2件: ESR1, ESR2 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
155 | Prostate cancer 3 genes, 4 drugs (DrugBank) and 44 diseases shown |
1件: AR |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
156 | Proteoglycans in cancer 5 genes, 11 drugs (DrugBank) and 74 diseases shown |
1件: ESR1 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
157 | Purine metabolism 14 genes, 8 drugs (DrugBank) and 53 diseases shown |
1件: HPRT1 |
D00161 |
Mercaptopurine |
5件: 86, 94, 96, 97, 164 |
D04931 |
2件: IMPDH1, IMPDH2 |
D00752 |
Mycophenolate mofetil |
32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
D05094 |
D05095 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
1件: RRM1 |
D03546 |
Clofarabine |
9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
1件: XDH |
D00224 |
Allopurinol |
6件: 6, 46, 57, 66, 96, 97 |
158 | Pyrimidine metabolism 1 gene, 2 drugs (DrugBank) and 21 diseases shown |
1件: RRM1 |
D03546 |
Clofarabine |
9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 |
D01907 |
Fludarabine |
17件: 13, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 |
D07966 |
159 | Rap1 signaling pathway 9 genes, 7 drugs (DrugBank) and 27 diseases shown |
1件: ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
1件: CNR1 |
D10915 |
Cannabidiol |
14件: 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
3件: GRIN1, GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
160 | Ras signaling pathway 6 genes, 4 drugs (DrugBank) and 14 diseases shown |
3件: GRIN1, GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: KIT |
D10229 |
Masitinib |
6件: 2, 5, 6, 13, 46, 96 |
161 | Regulation of actin cytoskeleton 3 genes, 4 drugs (DrugBank) and 13 diseases shown |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
2件: ITGA4, ITGB7 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: ITGB7 |
D09901 |
Etrolizumab |
2件: 96, 97 |
162 | Regulation of lipolysis in adipocytes 7 genes, 4 drugs (DrugBank) and 19 diseases shown |
2件: ADORA1, PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
3件: ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
163 | Renin secretion 17 genes, 5 drugs (DrugBank) and 45 diseases shown |
4件: ADORA1, PDE1B, PDE3A, PDE3B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
3件: ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
164 | Renin-angiotensin system 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
165 | Retrograde endocannabinoid signaling 22 genes, 4 drugs (DrugBank) and 23 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
1件: CNR1 |
D10915 |
Cannabidiol |
14件: 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
166 | Rheumatoid arthritis 21 genes, 15 drugs (DrugBank) and 55 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: CTLA4 |
D06657 |
Tremelimumab |
2件: 65, 96 |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: IL23A |
D10438 |
Guselkumab |
3件: 37, 96, 97 |
D11123 |
Mirikizumab |
2件: 96, 97 |
D11052 |
Risankizumab |
4件: 37, 96, 97, 271 |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
167 | RIG-I-like receptor signaling pathway 3 genes, 7 drugs (DrugBank) and 45 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
168 | Salivary secretion 6 genes, 1 drug (DrugBank) and 9 diseases shown |
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
169 | Serotonergic synapse 9 genes, 5 drugs (DrugBank) and 18 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
3件: GABRB1, GABRB2, GABRB3 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
1件: HTR4 |
D08236 |
Mosapride |
1件: 96 |
D09205 |
Prucalopride |
3件: 13, 51, 96 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
170 | Shigellosis 2 genes, 8 drugs (DrugBank) and 67 diseases shown |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
171 | Signaling pathways regulating pluripotency of stem cells 4 genes, 4 drugs (DrugBank) and 17 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
3件: JAK1, JAK2, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
172 | Small cell lung cancer 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
173 | Sphingolipid signaling pathway 8 genes, 9 drugs (DrugBank) and 49 diseases shown |
1件: ADORA1 |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
1件: OPRD1 |
D02095 |
Naltrexone |
11件: 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97 |
D05113 |
5件: S1PR1, S1PR2, S1PR3, S1PR4, S1PR5 |
D10968 |
Ozanimod |
3件: 13, 96, 97 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
174 | Staphylococcus aureus infection 15 genes, 2 drugs (DrugBank) and 11 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
175 | Synaptic vesicle cycle 2 genes, 1 drug (DrugBank) and 2 diseases shown |
2件: SLC6A2, SLC6A3 |
D00817 |
Bupropion |
2件: 8, 96 |
D07591 |
D07938 |
176 | Systemic lupus erythematosus 20 genes, 10 drugs (DrugBank) and 55 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: ELANE |
D03788 |
Sivelestat |
3件: 13, 85, 96 |
2件: GRIN2A, GRIN2B |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
177 | T cell receptor signaling pathway 11 genes, 11 drugs (DrugBank) and 57 diseases shown |
3件: CD3D, CD3E, CD3G |
D05092 |
Muromonab |
3件: 60, 96, 97 |
D06314 |
Visilizumab |
2件: 96, 97 |
1件: CTLA4 |
D06657 |
Tremelimumab |
2件: 65, 96 |
1件: PDCD1 |
D10316 |
Nivolumab |
10件: 13, 26, 41, 46, 49, 50, 51, 53, 96, 97 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
178 | Taste transduction 11 genes, 4 drugs (DrugBank) and 17 diseases shown |
1件: CACNA1C |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
1件: PDE1B |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
3件: SCN2A, SCN3A, SCN9A |
D01450 |
Bupivacaine |
7件: 46, 53, 70, 96, 168, 226, 298 |
D07552 |
179 | Terpenoid backbone biosynthesis 2 genes, 5 drugs (DrugBank) and 26 diseases shown |
1件: FDPS |
D00942 |
Risedronic acid |
7件: 46, 66, 93, 95, 96, 113, 274 |
D03234 |
D08484 |
D01968 |
Zoledronic acid |
11件: 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00893 |
Pravastatin |
9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 |
D08410 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
180 | TGF-beta signaling pathway 2 genes, 7 drugs (DrugBank) and 43 diseases shown |
1件: SMAD7 |
D10956 |
Mongersen |
2件: 96, 97 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
181 | Th1 and Th2 cell differentiation 28 genes, 8 drugs (DrugBank) and 40 diseases shown |
3件: CD3D, CD3E, CD3G |
D05092 |
Muromonab |
3件: 60, 96, 97 |
D06314 |
Visilizumab |
2件: 96, 97 |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
182 | Th17 cell differentiation 29 genes, 14 drugs (DrugBank) and 60 diseases shown |
3件: CD3D, CD3E, CD3G |
D05092 |
Muromonab |
3件: 60, 96, 97 |
D06314 |
Visilizumab |
2件: 96, 97 |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: IL23A |
D10438 |
Guselkumab |
3件: 37, 96, 97 |
D11123 |
Mirikizumab |
2件: 96, 97 |
D11052 |
Risankizumab |
4件: 37, 96, 97, 271 |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: RARA |
D01418 |
Tamibarotene |
2件: 26, 96 |
183 | Thermogenesis 4 genes, 5 drugs (DrugBank) and 55 diseases shown |
1件: ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: CNR1 |
D10915 |
Cannabidiol |
14件: 2, 6, 13, 46, 95, 96, 97, 140, 144, 145, 157, 158, 193, 271 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
184 | Thyroid cancer 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
185 | Thyroid hormone signaling pathway 5 genes, 4 drugs (DrugBank) and 41 diseases shown |
1件: ESR1 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
3件: HDAC1, HDAC2, HDAC3 |
D06320 |
Vorinostat |
2件: 19, 96 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
186 | Tight junction 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: CACNA1D |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
187 | TNF signaling pathway 2 genes, 7 drugs (DrugBank) and 47 diseases shown |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
188 | Toll-like receptor signaling pathway 7 genes, 10 drugs (DrugBank) and 53 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IFNAR1, IFNAR2 |
D03305 |
Interferon alfa |
5件: 25, 26, 28, 56, 96 |
D04554 |
Interferon beta-1a |
5件: 13, 14, 26, 96, 97 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
189 | Toxoplasmosis 20 genes, 11 drugs (DrugBank) and 47 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
190 | Transcriptional misregulation in cancer 8 genes, 8 drugs (DrugBank) and 39 diseases shown |
1件: CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: ELANE |
D03788 |
Sivelestat |
3件: 13, 85, 96 |
2件: HDAC1, HDAC2 |
D06320 |
Vorinostat |
2件: 19, 96 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: ITGB7 |
D09901 |
Etrolizumab |
2件: 96, 97 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
1件: RARA |
D01418 |
Tamibarotene |
2件: 26, 96 |
191 | Tuberculosis 26 genes, 19 drugs (DrugBank) and 63 diseases shown |
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL23A |
D10438 |
Guselkumab |
3件: 37, 96, 97 |
D11123 |
Mirikizumab |
2件: 96, 97 |
D11052 |
Risankizumab |
4件: 37, 96, 97, 271 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
1件: VDR |
D01518 |
Alfacalcidol |
6件: 41, 46, 49, 50, 96, 235 |
D00129 |
Calcitriol |
8件: 37, 46, 49, 66, 96, 158, 235, 326 |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
192 | Type I diabetes mellitus 25 genes, 9 drugs (DrugBank) and 52 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
193 | Type II diabetes mellitus 5 genes, 10 drugs (DrugBank) and 71 diseases shown |
2件: CACNA1C, CACNA1D |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
1件: INSR |
D00085 |
Insulin Human |
2件: 96, 156 |
D03230 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
194 | Ubiquinone and other terpenoid-quinone biosynthesis 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: NQO1, VKORC1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
195 | Vascular smooth muscle contraction 9 genes, 4 drugs (DrugBank) and 28 diseases shown |
1件: ADORA2A |
D00528 |
Caffeine |
6件: 2, 6, 46, 78, 96, 97 |
D01453 |
3件: ADRA1A, ADRA1B, ADRA1D |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00619 |
Verapamil |
4件: 96, 130, 140, 167 |
D02356 |
196 | VEGF signaling pathway 6 genes, 2 drugs (DrugBank) and 36 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
197 | Viral carcinogenesis 19 genes, 5 drugs (DrugBank) and 16 diseases shown |
11件: HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9 |
D06320 |
Vorinostat |
2件: 19, 96 |
6件: HLA-A, HLA-B, HLA-C, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
D10994 |
Upadacitinib |
6件: 41, 46, 49, 96, 97, 271 |
2件: JAK1, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
198 | Viral myocarditis 23 genes, 3 drugs (DrugBank) and 29 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
20件: HLA-A, HLA-B, HLA-C, HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, HLA-E, HLA-F, HLA-G |
D04318 |
Glatiramer |
4件: 2, 13, 96, 156 |
1件: ITGAL |
D03959 |
Efalizumab |
9件: 11, 13, 37, 46, 49, 53, 61, 95, 96 |
199 | Viral protein interaction with cytokine and cytokine receptor 1 gene, 6 drugs (DrugBank) and 43 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
200 | Wnt signaling pathway 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
201 | Yersinia infection 2 genes, 8 drugs (DrugBank) and 47 diseases shown |
1件: ITGA4 |
D06886 |
Natalizumab |
6件: 13, 15, 25, 46, 63, 96 |
D08083 |
Vedolizumab |
2件: 96, 97 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D03441 |
Certolizumab pegol |
6件: 37, 46, 96, 97, 226, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |