No. |
Drug (Description in trials) |
DrugBank |
KEGG DRUG * |
KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 |
Dichlorphenamide |
Diclofenamide |
D00518 |
[13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 |
[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation |
[1] 114 |
2 |
Lamotrigine |
Lamotrigine |
D00354 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[3] 13, 34, 114 |
3 |
Mexiletine |
Mexiletine |
D00639, D08215 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[5] 1, 2, 10, 113, 114 |
4 |
Mexitil |
Mexiletine |
D00639, D08215 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[1] 114 |
5 |
Ranolazine |
Ranolazine |
D05700, D05701 |
- |
- |
[6] 2, 58, 86, 113, 114, 130 |