No. |
Drug (Description in trials) |
DrugBank |
KEGG DRUG * |
KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 |
(r)-[n-metil-11c1-pk11195(pk) |
- |
- |
- |
- |
[1] 127 |
2 |
18f-av-1451 |
Flortaucipir f-18 |
- |
- |
- |
[3] 5, 7, 127 |
3 |
18f-av-45 |
- |
- |
- |
- |
[2] 6, 127 |
4 |
18f-fdg |
Fludeoxyglucose f-18 |
- |
- |
- |
[7] 6, 13, 46, 53, 84, 127, 300 |
5 |
18f-ro6958948 |
- |
- |
- |
- |
[3] 5, 7, 127 |
6 |
Al001 |
- |
- |
- |
- |
[1] 127 |
7 |
Amantadine |
Amantadine |
D00777, D07441 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
[17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway |
[4] 6, 8, 13, 127 |
8 |
Amiodarone |
Amiodarone |
D00636, D02910 |
[15] ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNJ11, KCNJ12, KCNJ3, KCNJ5, KCNJ8, KCNQ1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[30] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy (DCM), Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway |
[2] 28, 127 |
9 |
Amyvid |
- |
- |
- |
- |
[1] 127 |
10 |
Biib092 |
- |
- |
- |
- |
[3] 5, 7, 127 |
11 |
C-11 pib |
Pittsburgh compound b |
- |
- |
- |
[1] 127 |
12 |
Carbonate |
Carbonate ion |
- |
- |
- |
[10] 2, 13, 17, 19, 46, 75, 96, 127, 235, 299 |
13 |
Chloride |
Chloride ion |
- |
- |
- |
[17] 6, 11, 13, 14, 34, 46, 51, 96, 97, 127, 168, 193, 227, 228, 288, 297, 299 |
14 |
Citalopram |
Citalopram |
D00822, D07704 |
[1] SLC6A4 |
[2] Serotonergic synapse, Synaptic vesicle cycle |
[3] 8, 46, 127 |
15 |
Davunetide |
Davunetide |
D09401 |
- |
- |
[3] 5, 7, 127 |
16 |
Davunetide (al-108, nap) |
Davunetide |
D09401 |
- |
- |
[3] 5, 7, 127 |
17 |
Donepezil |
Donepezil |
D00670, D07869 |
[1] ACHE |
[2] Cholinergic synapse, Glycerophospholipid metabolism |
[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 |
18 |
F 18 t807 |
- |
- |
- |
- |
[1] 127 |
19 |
F-18 |
- |
- |
- |
- |
[2] 5, 127 |
20 |
F-18 fdg |
- |
- |
- |
- |
[1] 127 |
21 |
Ferulic acid |
Ferulic acid |
- |
- |
- |
[1] 127 |
22 |
Florbetapir (18f) |
- |
- |
- |
- |
[1] 127 |
23 |
Florbetapir 18f |
- |
- |
- |
- |
[1] 127 |
24 |
Florbetapir 18f injection |
- |
- |
- |
- |
[1] 127 |
25 |
Flutemetamol |
Flutemetamol |
- |
- |
- |
[5] 5, 6, 7, 17, 127 |
26 |
Frm-0334 |
- |
- |
- |
- |
[1] 127 |
27 |
Galantamine |
Galantamine |
D02173, D04292 |
[1] ACHE |
[2] Cholinergic synapse, Glycerophospholipid metabolism |
[2] 6, 127 |
28 |
Galantamine hydrobromide |
Galantamine |
D02173, D04292 |
[1] ACHE |
[2] Cholinergic synapse, Glycerophospholipid metabolism |
[1] 127 |
29 |
Intranasal oxytocin |
Oxytocin |
D00089 |
[1] OXTR |
[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
[2] 127, 193 |
30 |
Leucine |
L-leucine |
D00030 |
- |
- |
[7] 5, 6, 7, 127, 283, 284, 299 |
31 |
Leuco-methylthioninium bis(hydromethanesulfonate) |
Methylthioninium |
- |
- |
- |
[1] 127 |
32 |
Lithium carbonate |
Lithium carbonate |
D00801 |
- |
- |
[5] 2, 13, 17, 19, 127 |
33 |
Lmtm/trx0237 |
- |
- |
- |
- |
[1] 127 |
34 |
Memantine |
Memantine |
D04905, D08174 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
[17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway |
[7] 2, 6, 8, 13, 49, 127, 205 |
35 |
Memantine hydrochloride |
Memantine |
D04905, D08174 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
[17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway |
[3] 2, 6, 127 |
36 |
Methylthioninium |
Methylthioninium |
- |
- |
- |
[1] 127 |
37 |
Methylthioninium chloride |
Methylthioninium |
- |
- |
- |
[1] 127 |
38 |
Mtc trx0014-001 capsules |
- |
- |
- |
- |
[1] 127 |
39 |
N,n,n',n'-tetramethyl-10h-phenothiazine-3,7-diaminium bis(methanesulfonate) |
Phenothiazine |
D02601 |
- |
- |
[1] 127 |
40 |
N,n,n’,n’-tetramethyl-10h-phenothiazine-3,7-diaminium bis(methanesulfonate) |
Phenothiazine |
D02601 |
- |
- |
[1] 127 |
41 |
Neurohormonal mechanisms |
- |
- |
- |
- |
[2] 6, 127 |
42 |
Novolin-r insulin |
- |
- |
- |
- |
[1] 127 |
43 |
Oxytocin |
Oxytocin |
D00089 |
[1] OXTR |
[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
[4] 127, 193, 206, 226 |
44 |
Phenothiazine |
Phenothiazine |
D02601 |
- |
- |
[1] 127 |
45 |
Pittsburgh compound b |
Pittsburgh compound b |
- |
- |
- |
[2] 6, 127 |
46 |
Pittsburgh compound b (c-11 pib) |
Pittsburgh compound b |
- |
- |
- |
[1] 127 |
47 |
Saline nasal mist |
- |
- |
- |
- |
[1] 127 |
48 |
Syntocinon |
Oxytocin |
D00089 |
[1] OXTR |
[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
[2] 127, 193 |
49 |
T807 |
- |
- |
- |
- |
[1] 127 |
50 |
Tau (18-f-av-1451) |
- |
- |
- |
- |
[1] 127 |
51 |
Tolcapone |
Tolcapone |
D00786 |
[1] COMT |
[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism |
[3] 6, 28, 127 |
52 |
Trx0237 |
- |
- |
- |
- |
[1] 127 |
53 |
Vizamyl |
- |
- |
- |
- |
[3] 5, 7, 127 |
54 |
Vizamyl (flutemetamol(f-18)) |
Flutemetamol |
- |
- |
- |
[3] 5, 7, 127 |