No. |
Drug (Description in trials) |
DrugBank |
KEGG DRUG * |
KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 |
Calcium |
Calcium |
- |
- |
- |
[24] 6, 13, 19, 46, 49, 51, 65, 68, 75, 79, 84, 93, 94, 95, 96, 97, 214, 215, 222, 224, 235, 265, 298, 299 |
2 |
Calcium gluconate |
Calcium gluconate |
D00935 |
- |
- |
[3] 214, 215, 235 |
3 |
Coenzyme q10 |
Ubidecarenone |
D01065 |
- |
- |
[10] 2, 6, 8, 10, 46, 57, 113, 193, 214, 215 |
4 |
Dexmedetomidine |
Dexmedetomidine |
D00514, D01205 |
[3] ADRA2A, ADRA2B, ADRA2C |
[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway |
[11] 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
5 |
Dexmedetomidine and fentanyl |
Dexmedetomidine |
D00514, D01205 |
[3] ADRA2A, ADRA2B, ADRA2C |
[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway |
[1] 215 |
6 |
Dobutamine |
Dobutamine |
D00632, D03879, D03880, D03881 |
[1] ADRB1 |
[10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway |
[3] 57, 58, 215 |
7 |
Eplerenone |
Eplerenone |
D01115 |
[1] NR3C2 |
[1] Aldosterone-regulated sodium reabsorption |
[3] 75, 113, 215 |
8 |
Fentanyl |
Fentanyl |
D00320, D01399 |
[1] OPRM1 |
[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction |
[5] 46, 70, 85, 215, 231 |
9 |
Fluorescite |
Fluorescein |
D01261, D02024 |
- |
- |
[1] 215 |
10 |
Ketamine |
Ketamine |
D00711, D08098 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
[17] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Rap1 signaling pathway, Ras signaling pathway, Systemic lupus erythematosus, cAMP signaling pathway |
[5] 13, 70, 113, 156, 215 |
11 |
Losartan |
Losartan |
D00357, D08146 |
[1] AGTR1 |
[14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway |
[18] 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
12 |
Losartan potassium |
Potassium |
D08403 |
- |
- |
[4] 98, 167, 179, 215 |
13 |
Potassium |
Potassium |
D08403 |
- |
- |
[9] 46, 66, 67, 98, 115, 167, 179, 215, 235 |
14 |
Recombinant human brain natriuretic peptide (rhbnp) |
- |
- |
- |
- |
[1] 215 |
15 |
Sodium citrate |
Sodium citrate |
D01781, D05855 |
- |
- |
[3] 214, 215, 235 |
16 |
Tranexamic acid |
Tranexamic acid |
D01136 |
[1] PLG |
[4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection |
[5] 46, 70, 215, 227, 288 |