No. |
Drug (Description in trials) |
DrugBank |
KEGG DRUG * |
KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 |
Ace i, ata ii and statins |
- |
- |
- |
- |
[1] 218 |
2 |
Ace-inhibitor |
- |
- |
- |
- |
[1] 218 |
3 |
At1-inhibitor |
- |
- |
- |
- |
[1] 218 |
4 |
Bardoxolone |
Bardoxolone |
D09584 |
- |
- |
[7] 66, 67, 84, 85, 86, 218, 222 |
5 |
Bardoxolone methyl |
Bardoxolone methyl |
D09585 |
- |
- |
[7] 66, 67, 84, 85, 86, 218, 222 |
6 |
Benazepril |
Benazepril |
D00620, D07499 |
[1] ACE |
[4] Chagas disease (American trypanosomiasis), Hypertrophic cardiomyopathy (HCM), Renin secretion, Renin-angiotensin system |
[3] 57, 218, 224 |
7 |
Benazepril, valsartan and fluvastatin |
Fluvastatin |
D00892, D07983 |
[1] HMGCR |
[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis |
[1] 218 |
8 |
Fluvastatin |
Fluvastatin |
D00892, D07983 |
[1] HMGCR |
[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis |
[3] 79, 218, 222 |
9 |
Hmg-coenzyme inhibitor (statin) |
- |
- |
- |
- |
[1] 218 |
10 |
Paricalcitol |
Paricalcitol |
D00930 |
[1] VDR |
[4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis |
[3] 19, 66, 218 |
11 |
Ramipril |
Ramipril |
D00421 |
[1] ACE |
[4] Chagas disease (American trypanosomiasis), Hypertrophic cardiomyopathy (HCM), Renin secretion, Renin-angiotensin system |
[7] 46, 49, 66, 67, 113, 218, 257 |
12 |
Rg012 |
- |
- |
- |
- |
[1] 218 |
13 |
Sar339375 |
- |
- |
- |
- |
[1] 218 |
14 |
Spironolactone |
Spironolactone |
D00443 |
[1] NR3C2 |
[1] Aldosterone-regulated sodium reabsorption |
[6] 58, 67, 86, 113, 218, 225 |
15 |
Valsartan |
Valsartan |
D00400 |
[1] AGTR1 |
[14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway |
[6] 57, 58, 66, 75, 218, 222 |