No. |
Drug (Description in trials) |
DrugBank |
KEGG DRUG * |
KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 |
Acei |
- |
- |
- |
- |
[2] 66, 224 |
2 |
Acetate |
Acetate |
- |
- |
- |
[40] 1, 2, 6, 10, 13, 35, 40, 46, 49, 51, 60, 64, 70, 71, 73, 75, 76, 78, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 235, 265, 288, 298, 299 |
3 |
Angiotensin |
Angiotensin ii |
D00150, D02014 |
[2] AGTR1, AGTR2 |
[14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway |
[7] 17, 19, 46, 66, 86, 222, 224 |
4 |
Angiotensin-converting enzyme (ace) inhibitor |
Angiotensin ii |
D00150, D02014 |
[2] AGTR1, AGTR2 |
[14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway |
[1] 224 |
5 |
Angiotensin-converting enzyme inhibitor(acei) |
Angiotensin ii |
D00150, D02014 |
[2] AGTR1, AGTR2 |
[14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway |
[1] 224 |
6 |
Benazepril |
Benazepril |
D00620, D07499 |
[1] ACE |
[4] Chagas disease (American trypanosomiasis), Hypertrophic cardiomyopathy (HCM), Renin secretion, Renin-angiotensin system |
[3] 57, 218, 224 |
7 |
Benazepril hydrochloride tablets |
Benazepril |
D00620, D07499 |
[1] ACE |
[4] Chagas disease (American trypanosomiasis), Hypertrophic cardiomyopathy (HCM), Renin secretion, Renin-angiotensin system |
[1] 224 |
8 |
Calcium |
Calcium |
- |
- |
- |
[24] 6, 13, 19, 46, 49, 51, 65, 68, 75, 79, 84, 93, 94, 95, 96, 97, 214, 215, 222, 224, 235, 265, 298, 299 |
9 |
Chinese herbs based on syndrome differentiation |
- |
- |
- |
- |
[1] 224 |
10 |
Cyclophosphamide |
Cyclophosphamide |
D00287, D07760 |
- |
- |
[43] 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 61, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 222, 224, 265, 274, 283, 284, 285, 288, 326, 331 |
11 |
Cyclophosphamide(ctx) |
Cyclophosphamide |
D00287, D07760 |
- |
- |
[1] 224 |
12 |
Dipyridamole |
Dipyridamole |
D00302 |
[2] PDE4A, PDE5A |
[6] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway |
[5] 46, 49, 51, 66, 224 |
13 |
Dipyridamole tab 25 mg |
Dipyridamole |
D00302 |
[2] PDE4A, PDE5A |
[6] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway |
[1] 224 |
14 |
Glycosides of tripterygium wilfordii hook(gtw) |
Tripterygium wilfordii whole |
- |
- |
- |
[1] 224 |
15 |
Heparin |
Heparin |
D07510 |
[1] SERPINC1 |
[1] Complement and coagulation cascades |
[11] 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 |
16 |
Leflunomide |
Leflunomide |
D00749 |
[1] DHODH |
[2] Metabolic pathways, Pyrimidine metabolism |
[9] 11, 40, 46, 49, 53, 66, 224, 271, 300 |
17 |
Leflunomide(lef) |
Leflunomide |
D00749 |
[1] DHODH |
[2] Metabolic pathways, Pyrimidine metabolism |
[1] 224 |
18 |
Low molecular weight heparin calcium injection |
Calcium, Heparin |
D07510 |
[1] SERPINC1 |
[1] Complement and coagulation cascades |
[1] 224 |
19 |
Methylprednisolone |
Methylprednisolone |
D00407, D00751, D00979, D05000, D05001, D05002 |
[1] NR3C1 |
[1] Neuroactive ligand-receptor interaction |
[36] 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 |
20 |
Mizoribine |
Mizoribine |
D01392 |
[2] IMPDH1, IMPDH2 |
[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
[7] 49, 51, 53, 66, 94, 222, 224 |
21 |
Mycophenolate |
Mycophenolic acid |
D05096 |
[2] IMPDH1, IMPDH2 |
[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
[33] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
22 |
Mycophenolate mofetil |
Mycophenolate mofetil |
D00752, D05094, D05095 |
[2] IMPDH1, IMPDH2 |
[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
[32] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
23 |
Mycophenolate mofetil(mmf) |
Mycophenolate mofetil |
D00752, D05094, D05095 |
[2] IMPDH1, IMPDH2 |
[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
[1] 224 |
24 |
Prednisone |
Prednisone |
D00473 |
[1] NR3C1 |
[1] Neuroactive ligand-receptor interaction |
[43] 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
25 |
Prednisone acetate |
Prednisone acetate |
D08416 |
[1] NR3C1 |
[1] Neuroactive ligand-receptor interaction |
[3] 40, 49, 224 |
26 |
Prednisone acetate tablets |
Prednisone acetate |
D08416 |
[1] NR3C1 |
[1] Neuroactive ligand-receptor interaction |
[1] 224 |
27 |
Qi-ji shen-kang formula |
- |
- |
- |
- |
[1] 224 |
28 |
Sulfotanshinone sodium injection |
- |
- |
- |
- |
[1] 224 |
29 |
Tacrolimus |
Tacrolimus |
D00107, D08556 |
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
[30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
[29] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
30 |
Tripterygium |
Tripterygium wilfordii whole |
- |
- |
- |
[8] 46, 66, 67, 96, 162, 222, 224, 271 |
31 |
Tripterygium wilfordii |
Tripterygium wilfordii whole |
- |
- |
- |
[6] 46, 66, 67, 222, 224, 271 |