No. |
Drug (Description in trials) |
DrugBank |
KEGG DRUG * |
KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 |
2% sodium chondroitin sulfate |
Chondroitin sulfate |
D00080 |
- |
- |
[1] 226 |
2 |
5% lidocaine/5 mg/ml estradiol compound cream |
Estradiol, Lidocaine |
D00105, D00358, D01413, D01617, D01953, D02086, D04061, D04063, D04064, D04065, D08127 |
[7] ESR1, ESR2, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[12] Adrenergic signaling in cardiomyocytes, Breast cancer, Dopaminergic synapse, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Taste transduction, Thyroid hormone signaling pathway |
[1] 226 |
3 |
Adalimumab |
Adalimumab |
D02597 |
[1] TNF |
[61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway |
[15] 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
4 |
Agn 203818 |
- |
- |
- |
- |
[1] 226 |
5 |
Alkalinized lidocaine-heparin |
Lidocaine |
D00358, D02086, D08127 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[1] 226 |
6 |
Amitriptyline |
Amitriptyline |
D00809, D07448 |
[2] SLC6A2, SLC6A4 |
[2] Serotonergic synapse, Synaptic vesicle cycle |
[3] 78, 226, 299 |
7 |
Aqx-1125 |
- |
- |
- |
- |
[1] 226 |
8 |
Aqx-1125 100 mg |
- |
- |
- |
- |
[1] 226 |
9 |
Aqx-1125 200 mg |
- |
- |
- |
- |
[1] 226 |
10 |
Asp3652 |
- |
- |
- |
- |
[1] 226 |
11 |
Asp6294 |
- |
- |
- |
- |
[1] 226 |
12 |
Bladder instillation with heparin/ lidocaine |
Lidocaine |
D00358, D02086, D08127 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[1] 226 |
13 |
Bladder instillation with triamcinolone acetonide |
Triamcinolone |
D00385, D00983, D00984, D00985, D06216 |
[1] NR3C1 |
[1] Neuroactive ligand-receptor interaction |
[1] 226 |
14 |
Bladder instillation without triamcinolone acetonide |
Triamcinolone |
D00385, D00983, D00984, D00985, D06216 |
[1] NR3C1 |
[1] Neuroactive ligand-receptor interaction |
[1] 226 |
15 |
Bladder instillations |
- |
- |
- |
- |
[1] 226 |
16 |
Botox |
Botulinum toxin type a |
D00783 |
[1] SNAP25 |
[2] Insulin secretion, Synaptic vesicle cycle |
[4] 6, 13, 149, 226 |
17 |
Botox 200u in normal saline |
- |
- |
- |
- |
[1] 226 |
18 |
Botulinum toxin a |
Botulinum toxin type a |
D00783 |
[1] SNAP25 |
[2] Insulin secretion, Synaptic vesicle cycle |
[4] 13, 51, 149, 226 |
19 |
Buckwheat |
Buckwheat |
- |
- |
- |
[1] 226 |
20 |
Bupivacaine |
Bupivacaine |
D01450, D07552 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[7] 46, 53, 70, 96, 168, 226, 298 |
21 |
Capsaicin |
Capsaicin |
D00250 |
[1] TRPV1 |
[2] Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction |
[6] 2, 6, 19, 86, 113, 226 |
22 |
Certolizumab pegol |
Certolizumab pegol |
D03441 |
[1] TNF |
[61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway |
[6] 37, 46, 96, 97, 226, 271 |
23 |
Chondroitin sulfate |
Chondroitin sulfate |
D00080 |
- |
- |
[2] 96, 226 |
24 |
Ciclosporin |
Ciclosporin |
D00184 |
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
[30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
[13] 26, 46, 49, 50, 53, 55, 60, 61, 97, 222, 226, 228, 269 |
25 |
Ciklosporin |
- |
- |
- |
- |
[1] 226 |
26 |
Cyclosporine |
Ciclosporin |
D00184 |
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
[30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
[33] 11, 14, 19, 20, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 56, 58, 60, 62, 64, 65, 90, 95, 97, 162, 164, 222, 226, 228, 234, 283, 284, 285, 302 |
27 |
Dexmedetomidine |
Dexmedetomidine |
D00514, D01205 |
[3] ADRA2A, ADRA2B, ADRA2C |
[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway |
[11] 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
28 |
Dimethyl sulfoxide |
Dimethyl sulfoxide |
D01043 |
- |
- |
[1] 226 |
29 |
Dmso |
Dimethyl sulfoxide |
D01043 |
- |
- |
[1] 226 |
30 |
Dmso cocktail |
Dimethyl sulfoxide |
D01043 |
- |
- |
[1] 226 |
31 |
Erb-041 |
- |
- |
- |
- |
[3] 46, 96, 226 |
32 |
Estradiol |
Estradiol |
D00105, D01413, D01617, D01953, D04061, D04063, D04064, D04065 |
[2] ESR1, ESR2 |
[9] Breast cancer, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway |
[5] 13, 46, 49, 226, 299 |
33 |
Fospropofol |
Fospropofol |
D04257 |
- |
- |
[1] 226 |
34 |
Fospropofol (lusedra®) 10 |
Fospropofol |
D04257 |
- |
- |
[1] 226 |
35 |
Fospropofol (lusedra®) 12 |
Fospropofol |
D04257 |
- |
- |
[1] 226 |
36 |
Fospropofol (lusedra®) 6.5 |
Fospropofol |
D04257 |
- |
- |
[1] 226 |
37 |
Gefapixant |
Gefapixant |
D11349 |
[1] P2RX3 |
[3] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Taste transduction |
[2] 85, 226 |
38 |
Glycine |
Glycine |
D00011 |
- |
- |
[4] 35, 86, 226, 299 |
39 |
Gralise |
Gabapentin |
D00332 |
[5] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4, SLC6A1 |
[9] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy (DCM), GABAergic synapse, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Oxytocin signaling pathway, Synaptic vesicle cycle |
[2] 97, 226 |
40 |
Heparin |
Heparin |
D07510 |
[1] SERPINC1 |
[1] Complement and coagulation cascades |
[11] 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 |
41 |
Hyaluronic acid |
Hyaluronic acid |
D08043 |
- |
- |
[5] 46, 53, 70, 226, 231 |
42 |
Hyaluronic acid and chondroitin sulfate |
Chondroitin sulfate |
D00080 |
- |
- |
[1] 226 |
43 |
Hyaluronic acid/chondroitin sulfate |
Chondroitin sulfate |
D00080 |
- |
- |
[1] 226 |
44 |
Hydrogen |
Hydrogen |
- |
- |
- |
[5] 5, 6, 17, 97, 226 |
45 |
Ic cocktail |
- |
- |
- |
- |
[1] 226 |
46 |
Intravesical onabotulinumtoxina injection |
Botulinum toxin type a |
D00783 |
[1] SNAP25 |
[2] Insulin secretion, Synaptic vesicle cycle |
[1] 226 |
47 |
Ipd® (japanese tradename) |
- |
- |
- |
- |
[1] 226 |
48 |
Ketorolac |
Ketorolac |
D00813, D08104 |
[2] PTGS1, PTGS2 |
[21] Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway |
[2] 70, 226 |
49 |
Ketorolac tromethamine |
Tromethamine |
D00396 |
- |
- |
[1] 226 |
50 |
Krp-116d |
- |
- |
- |
- |
[1] 226 |
51 |
Lidocaine |
Lidocaine |
D00358, D02086, D08127 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[8] 6, 13, 46, 86, 168, 226, 231, 256 |
52 |
Lidocaine releasing intravesical system - liris® |
Lidocaine |
D00358, D02086, D08127 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[1] 226 |
53 |
Liposome encapsulated bont-a |
- |
- |
- |
- |
[1] 226 |
54 |
Liposomes |
- |
- |
- |
- |
[1] 226 |
55 |
Liris 400 mg |
- |
- |
- |
- |
[1] 226 |
56 |
Liris low dose and liris high dose |
- |
- |
- |
- |
[1] 226 |
57 |
Liris® |
- |
- |
- |
- |
[1] 226 |
58 |
Liris® 400 mg |
- |
- |
- |
- |
[1] 226 |
59 |
Lp-08 20mg |
- |
- |
- |
- |
[1] 226 |
60 |
Lp-08 80mg |
- |
- |
- |
- |
[1] 226 |
61 |
Metoprolol |
Metoprolol |
D00601, D02358, D05011 |
[1] ADRB1 |
[10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway |
[6] 17, 57, 58, 113, 193, 226 |
62 |
Metoprolol tartrate oral tablet |
Metoprolol |
D00601, D02358, D05011 |
[1] ADRB1 |
[10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway |
[1] 226 |
63 |
Mirabegron |
Mirabegron |
D09535 |
[1] ADRB3 |
[7] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cGMP-PKG signaling pathway |
[3] 6, 13, 226 |
64 |
Mn-001 |
- |
- |
- |
- |
[1] 226 |
65 |
Mn-001 bid |
- |
- |
- |
- |
[1] 226 |
66 |
Mycofenolate mofetil (mmf) |
- |
- |
- |
- |
[1] 226 |
67 |
Mycophenolate |
Mycophenolic acid |
D05096 |
[2] IMPDH1, IMPDH2 |
[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
[33] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
68 |
Mycophenolate mofetil |
Mycophenolate mofetil |
D00752, D05094, D05095 |
[2] IMPDH1, IMPDH2 |
[3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism |
[32] 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
69 |
Naloxone |
Naloxone |
D01340, D08249 |
[3] OPRD1, OPRK1, OPRM1 |
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
[2] 6, 226 |
70 |
Naloxone hydrochloride |
Naloxone |
D01340, D08249 |
[3] OPRD1, OPRK1, OPRM1 |
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
[1] 226 |
71 |
Normal saline |
- |
- |
- |
- |
[14] 6, 17, 22, 36, 46, 49, 60, 94, 96, 211, 226, 276, 296, 299 |
72 |
Normal saline instillation |
- |
- |
- |
- |
[1] 226 |
73 |
Nortriptyline |
Nortriptyline |
D00816, D08288 |
[2] SLC6A2, SLC6A4 |
[2] Serotonergic synapse, Synaptic vesicle cycle |
[2] 6, 226 |
74 |
Omalizumab |
Omalizumab |
D05251 |
[1] FCER1A |
[4] Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway |
[6] 53, 65, 98, 162, 226, 299 |
75 |
Onabotulinumtoxin a |
- |
- |
- |
- |
[1] 226 |
76 |
Onabotulinumtoxina |
Botulinum toxin type a |
D00783 |
[1] SNAP25 |
[2] Insulin secretion, Synaptic vesicle cycle |
[3] 6, 13, 226 |
77 |
Oxn 10/5 mg pr |
- |
- |
- |
- |
[1] 226 |
78 |
Oxn 20/10 mg pr |
- |
- |
- |
- |
[1] 226 |
79 |
Oxn 5/2.5 mg pr |
- |
- |
- |
- |
[1] 226 |
80 |
Oxycodone |
Oxycodone |
D03783, D05312, D05462 |
[3] OPRD1, OPRK1, OPRM1 |
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
[7] 6, 13, 46, 70, 226, 231, 298 |
81 |
Oxycodone hydrochloride |
Oxycodone |
D03783, D05312, D05462 |
[3] OPRD1, OPRK1, OPRM1 |
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
[3] 70, 226, 298 |
82 |
Oxycodone naloxone prolonged release tablets |
Oxycodone |
D03783, D05312, D05462 |
[3] OPRD1, OPRK1, OPRM1 |
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
[1] 226 |
83 |
Oxycodone/naloxone prolonged release t |
Oxycodone |
D03783, D05312, D05462 |
[3] OPRD1, OPRK1, OPRM1 |
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
[1] 226 |
84 |
Oxycodone/naloxone prolonged release tablets 10/5 mg |
Oxycodone |
D03783, D05312, D05462 |
[3] OPRD1, OPRK1, OPRM1 |
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
[1] 226 |
85 |
Oxycodone/naloxone prolonged release tablets 20/10 mg |
Oxycodone |
D03783, D05312, D05462 |
[3] OPRD1, OPRK1, OPRM1 |
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
[1] 226 |
86 |
Oxycodone/naloxone prolonged release tablets 5/2.5 mg |
Oxycodone |
D03783, D05312, D05462 |
[3] OPRD1, OPRK1, OPRM1 |
[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway |
[1] 226 |
87 |
Oxygen |
Oxygen |
D00003 |
- |
- |
[14] 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 193, 226, 299, 330 |
88 |
Oxytocin |
Oxytocin |
D00089 |
[1] OXTR |
[4] Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway |
[4] 127, 193, 206, 226 |
89 |
Pd 0299685 |
- |
- |
- |
- |
[1] 226 |
90 |
Pd 0299685 at 15mg bid |
- |
- |
- |
- |
[1] 226 |
91 |
Pd 0299685 at 30mg bid |
- |
- |
- |
- |
[1] 226 |
92 |
Pentosan polysulfate |
Pentosan polysulfate |
D05428 |
- |
- |
[3] 19, 26, 226 |
93 |
Pentosan polysulfate sodium 100 mg |
Pentosan polysulfate |
D05428 |
- |
- |
[1] 226 |
94 |
Pf-04383119 |
- |
- |
- |
- |
[1] 226 |
95 |
Placebo |
- |
- |
- |
- |
[20] 3, 6, 13, 14, 40, 46, 49, 50, 51, 66, 67, 79, 85, 86, 88, 96, 97, 144, 149, 226 |
96 |
Platelet enriched plasma |
- |
- |
- |
- |
[1] 226 |
97 |
Platelet-rich plasma |
- |
- |
- |
- |
[1] 226 |
98 |
Prograf |
Tacrolimus |
D00107, D08556 |
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
[30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
[3] 60, 222, 226 |
99 |
Propiverine |
Propiverine |
D08441 |
[9] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 |
[40] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Pancreatic secretion, Regulation of actin cytoskeleton, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway |
[1] 226 |
100 |
Propiverine hydrochloride |
Propiverine |
D08441 |
[9] CACNA1C, CACNA1D, CACNA1F, CACNA1S, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 |
[40] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin secretion, Long-term potentiation, MAPK signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Pancreatic secretion, Regulation of actin cytoskeleton, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway |
[1] 226 |
101 |
Rimso |
Dimethyl sulfoxide |
D01043 |
- |
- |
[1] 226 |
102 |
Rimso 50 |
Dimethyl sulfoxide |
D01043 |
- |
- |
[1] 226 |
103 |
Rn624, ri624 |
- |
- |
- |
- |
[1] 226 |
104 |
Sandimmun |
Ciclosporin |
D00184 |
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
[30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
[4] 53, 60, 113, 226 |
105 |
Sandimmun neoral |
Ciclosporin |
D00184 |
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
[30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
[2] 60, 226 |
106 |
Sildenafil |
Sildenafil |
D02229, D08514 |
[1] PDE5A |
[3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway |
[15] 6, 46, 50, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
107 |
Sugar pill |
- |
- |
- |
- |
[7] 6, 49, 67, 70, 86, 206, 226 |
108 |
Sulfate |
Sulfate ion |
- |
- |
- |
[22] 2, 6, 11, 13, 26, 34, 36, 46, 49, 60, 61, 64, 66, 79, 86, 96, 222, 226, 265, 296, 297, 299 |
109 |
Suplatast tosilate |
- |
- |
- |
- |
[1] 226 |
110 |
Tacrolimus |
Tacrolimus |
D00107, D08556 |
[5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
[30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway |
[29] 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
111 |
Tanezumab |
Tanezumab |
D09387 |
[1] NGF |
[8] Apoptosis, Cytokine-cytokine receptor interaction, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Ras signaling pathway |
[2] 226, 298 |
112 |
Targinact 10 mg/5 mg prolonged-release tablets |
- |
- |
- |
- |
[1] 226 |
113 |
Targinact 20mg/10 mg prolonged-release tablets |
- |
- |
- |
- |
[1] 226 |
114 |
Targinact 5mg/2.5 mg prolonged-release tablets |
- |
- |
- |
- |
[1] 226 |
115 |
Tramadol |
Tramadol |
D01355, D08623 |
[1] OPRM1 |
[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction |
[5] 46, 70, 78, 226, 271 |
116 |
Triamcinolone |
Triamcinolone |
D00385, D00983, D00984, D00985, D06216 |
[1] NR3C1 |
[1] Neuroactive ligand-receptor interaction |
[8] 35, 46, 56, 70, 90, 96, 226, 298 |
117 |
Tromethamine |
Tromethamine |
D00396 |
- |
- |
[1] 226 |
118 |
Tti-1612 |
- |
- |
- |
- |
[1] 226 |
119 |
Urg101 |
- |
- |
- |
- |
[1] 226 |
120 |
Water |
Water |
D00001 |
- |
- |
[18] 2, 5, 6, 13, 17, 19, 35, 46, 53, 57, 63, 65, 67, 84, 97, 226, 278, 299 |
121 |
Ym672 |
- |
- |
- |
- |
[1] 226 |
122 |
Ym672 (ipd®) |
- |
- |
- |
- |
[1] 226 |