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   e.g. "Sirolimus", "Adalimumab"

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51 / 12,170 descriptions found* Show info (disease name, etc.) on mouse-over.
 No.   Drug (Description in trials)   DrugBank   KEGG DRUG *   KEGG GENES * 
 [Number of genes] 		  KEGG PATHWAY 
 [Number of pathways] 		  Disease ID * 
 [Number of diseases] 
 1   Avacopan   Avacopan   D11093   [1] C5AR1   [3] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection   [4]
43,
44,
222,
223 
 2   Azathioprine   Azathioprine   D00238, D03033   -   -   [18]
11,
13,
19,
35,
42,
43,
44,
45,
46,
49,
65,
66,
85,
94,
95,
96,
97,
162 
 3   Belimumab   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [8]
11,
43,
44,
46,
49,
51,
53,
222 
 4   Belimumab 10 mg/kg   Belimumab   D03068   [1] TNFSF13B   [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis   [3]
43,
46,
49 
 5   Blisibimod   Blisibimod   D10311   -   -   [5]
43,
44,
49,
63,
66 
 6   Ccx168   -   -   -   -   [6]
43,
44,
66,
109,
222,
223 
 7   Cellcept (mycophenolate mofetil)   Mycophenolate mofetil   D00752, D05094, D05095   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [2]
42,
43 
 8   Chimeric monoclonal antibody, igg4 subtype   -   -   -   -   [2]
43,
44 
 9   Corticosteroid   -   -   -   -   [10]
13,
42,
43,
44,
45,
66,
84,
96,
97,
222 
 10   Corticosteroid and azathioprine   Azathioprine   D00238, D03033   -   -   [4]
42,
43,
44,
45 
 11   Cyclophosphamide   Cyclophosphamide   D00287, D07760   -   -   [43]
13,
14,
16,
19,
20,
26,
28,
35,
36,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
52,
56,
60,
61,
62,
65,
66,
84,
85,
93,
96,
162,
164,
172,
222,
224,
265,
274,
283,
284,
285,
288,
326,
331 
 12   Cyclophosphamide, azathioprine,prednisone,methylprednisolone   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [3]
42,
43,
45 
 13   Freeze-dried sulfonated human normal immunoglobulin (ggs)   Immune globulin human   -   -   -   [3]
14,
43,
45 
 14   Galen® tablet   -   -   -   -   [2]
43,
44 
 15   Glucocorticoid (gc)   -   -   -   -   [2]
43,
44 
 16   Glucocorticoids   -   -   -   -   [6]
40,
41,
43,
44,
60,
62 
 17   Glucocorticoids (gc)   -   -   -   -   [2]
43,
44 
 18   Glucocorticoids - reduced dose   -   -   -   -   [2]
43,
44 
 19   Glucocorticoids - standard dose   -   -   -   -   [2]
43,
44 
 20   Human normal immunoglobulin   Immune globulin human   -   -   -   [8]
11,
13,
14,
43,
45,
50,
63,
65 
 21   Ifx-1   -   -   -   -   [3]
43,
44,
269 
 22   Infliximab   Infliximab   D02598   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [22]
35,
37,
38,
39,
40,
41,
43,
45,
46,
49,
50,
56,
65,
84,
95,
96,
97,
98,
162,
164,
269,
271 
 23   Intravenous immunoglobulins (human immunoglobulins g)   -   -   -   -   [1]
43 
 24   Intravenous methyl prednisolone   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
43 
 25   Mabthera®   -   -   -   -   [6]
13,
35,
43,
44,
46,
93 
 26   Methotrexate   Methotrexate   D00142, D02115   [2] DHFR, DHFR2   [4] Antifolate resistance, Folate biosynthesis, Metabolic pathways, One carbon pool by folate   [33]
11,
13,
19,
34,
35,
41,
42,
43,
44,
45,
46,
49,
50,
51,
53,
55,
56,
60,
62,
65,
84,
93,
96,
97,
162,
164,
172,
256,
271,
284,
285,
326,
331 
 27   Methyl prednisolone   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [3]
43,
49,
96 
 28   Methylprednisolone   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [36]
2,
13,
25,
26,
35,
38,
39,
40,
41,
42,
43,
45,
46,
49,
50,
51,
60,
63,
64,
65,
66,
83,
84,
86,
96,
97,
145,
164,
220,
222,
224,
271,
283,
284,
285,
296 
 29   Methylprednisolone (or other glucocorticoid)   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
43 
 30   Mycophenolate   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [33]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
84,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 31   Mycophenolate mofetil   Mycophenolate mofetil   D00752, D05094, D05095   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [32]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 32   Mycophenolate mofetil,methotrexate   Mycophenolate mofetil   D00752, D05094, D05095   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [3]
42,
43,
45 
 33   Naltrexone   Naltrexone   D02095, D05113   [3] OPRD1, OPRK1, OPRM1   [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway   [11]
6,
10,
13,
40,
41,
42,
43,
44,
45,
96,
97 
 34   Naltrexone hydrochloride   Naltrexone   D02095, D05113   [3] OPRD1, OPRK1, OPRM1   [5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway   [7]
10,
40,
41,
42,
43,
44,
45 
 35   Pednisone   -   -   -   -   [2]
43,
44 
 36   Placebo (physiological saline)   -   -   -   -   [2]
43,
45 
 37   Prednisolone   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [38]
11,
13,
25,
26,
35,
38,
39,
41,
43,
44,
45,
46,
49,
50,
51,
56,
60,
61,
63,
64,
65,
66,
75,
81,
84,
85,
95,
96,
97,
113,
145,
162,
222,
269,
271,
296,
299,
300 
 38   Prednison acis® 20 mg   -   -   -   -   [2]
43,
44 
 39   Prednison acis® 5 mg   -   -   -   -   [2]
43,
44 
 40   Prednisone   Prednisone   D00473   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [43]
2,
11,
13,
14,
26,
35,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
53,
61,
63,
64,
65,
66,
81,
84,
85,
86,
95,
96,
97,
113,
162,
164,
222,
224,
228,
251,
283,
284,
285,
288,
299,
300,
331 
 41   Prednisone (and methylprednisolone)   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [1]
43 
 42   Prednisone tablets, usp   Prednisone   D00473   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [3]
41,
43,
44 
 43   Prednisone, methylprednisolone,cyclophosphamides   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [3]
42,
43,
45 
 44   Rituximab   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [42]
11,
13,
14,
17,
35,
36,
43,
44,
45,
46,
49,
50,
51,
52,
53,
56,
60,
61,
63,
64,
65,
66,
83,
84,
85,
86,
93,
94,
96,
97,
162,
222,
223,
229,
256,
271,
283,
284,
285,
288,
300,
331 
 45   Rituximab (arm a)   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [2]
43,
44 
 46   Rituximab (arm b)   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [2]
43,
44 
 47   Rixathon 500mg   -   -   -   -   [1]
43 
 48   Ro0452294/v01   -   -   -   -   [2]
43,
44 
 49   Ro0452294/v02   -   -   -   -   [3]
35,
43,
44 
 50   Same   Ademetionine   D07128   -   -   [15]
6,
14,
22,
43,
44,
46,
47,
49,
50,
60,
84,
93,
96,
97,
172 
 51   Tocilizumab   Tocilizumab   D02596   [1] IL6R   [11] Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease (NAFLD), PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor   [16]
2,
13,
40,
41,
43,
46,
50,
51,
53,
54,
55,
86,
107,
266,
271,
331 

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