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   e.g. "Sirolimus", "Adalimumab"

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124 / 12,170 descriptions found* Show info (disease name, etc.) on mouse-over.
 No.   Drug (Description in trials)   DrugBank   KEGG DRUG *   KEGG GENES * 
 [Number of genes] 		  KEGG PATHWAY 
 [Number of pathways] 		  Disease ID * 
 [Number of diseases] 
 1   10% nifedipine cream   Nifedipine   D00437   [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   [34] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [1]
50 
 2   3 mpdn pulse + pdn   -   -   -   -   [1]
50 
 3   3 mpdn pulse + pdn + csa   -   -   -   -   [1]
50 
 4   3 mpdn pulse + pdn + mtx   -   -   -   -   [1]
50 
 5   44/154/85-c   -   -   -   -   [1]
50 
 6   44/196/81-c   -   -   -   -   [1]
50 
 7   5% sildenafil cream   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [1]
50 
 8   56/104/75-c   -   -   -   -   [1]
50 
 9   Abatacept   Abatacept   D03203   [2] CD80, CD86   [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis   [24]
11,
13,
19,
41,
44,
46,
49,
50,
51,
53,
55,
60,
65,
84,
93,
96,
97,
107,
164,
222,
271,
284,
285,
300 
 10   Abatacept subcutaneous   Abatacept   D03203   [2] CD80, CD86   [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis   [1]
50 
 11   Acthar   Corticotropin   D00146   [1] MC2R   [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [6]
2,
13,
46,
49,
50,
222 
 12   Adrenocorticotropic hormone   Corticotropin   D00146   [1] MC2R   [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [3]
13,
50,
84 
 13   Adrenocorticotropic hormone gel   Corticotropin   D00146   [1] MC2R   [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway   [1]
50 
 14   Ajulemic acid   Ajulemic acid   D11312   [1] CNR2   [1] Neuroactive ligand-receptor interaction   [3]
50,
51,
299 
 15   Alendronate   Alendronic acid   D00939, D07119   [1] FDPS   [4] Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis   [7]
19,
41,
46,
50,
271,
274,
299 
 16   Alendronate versus alfacalcidol (1-alpha oh vitamin d)   Alfacalcidol   D01518   [1] VDR   [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis   [3]
41,
46,
50 
 17   Alfacalcidol   Alfacalcidol   D01518   [1] VDR   [4] Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis   [6]
41,
46,
49,
50,
96,
235 
 18   Anakinra   Anakinra   D02934   [2] IL1R1, IL1R2   [15] Amoebiasis, Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Inflammatory mediator regulation of TRP channels, MAPK signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Pathogenic Escherichia coli infection, Prostate cancer, Shigellosis, Th17 cell differentiation, Transcriptional misregulation in cancer   [15]
2,
13,
15,
19,
37,
41,
46,
49,
50,
56,
84,
86,
106,
107,
299 
 19   Anti-pandemic h1n1 influenza vaccine   -   -   -   -   [5]
46,
49,
50,
51,
53 
 20   Apremilast   Apremilast   D08860   [4] PDE4A, PDE4B, PDE4C, PDE4D   [5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway   [5]
46,
50,
56,
97,
271 
 21   Apremilast 30mg   Apremilast   D08860   [4] PDE4A, PDE4B, PDE4C, PDE4D   [5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway   [1]
50 
 22   Baf312   -   -   -   -   [2]
13,
50 
 23   Baf312 0.25 mg   -   -   -   -   [1]
50 
 24   Baf312 0.25 mg tablet   -   -   -   -   [1]
50 
 25   Baf312 0.50 mg   -   -   -   -   [1]
50 
 26   Baf312 1 mg tablet   -   -   -   -   [2]
13,
50 
 27   Baf312 1mg   -   -   -   -   [1]
50 
 28   Baf312 2mg   -   -   -   -   [1]
50 
 29   Baf312 4mg tablet   -   -   -   -   [1]
50 
 30   Baf312 5 mg tablet   -   -   -   -   [1]
50 
 31   Baf312 hemifumarate   -   -   -   -   [2]
13,
50 
 32   Baf312x   -   -   -   -   [1]
50 
 33   Baricitinib   Baricitinib   D10308   [2] JAK1, JAK2   [32] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis   [8]
41,
46,
49,
50,
93,
107,
265,
325 
 34   Basiliximab   Basiliximab   D03058   [1] IL2RA   [11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor   [6]
2,
50,
65,
97,
222,
228 
 35   Calcineurin inhibitors   -   -   -   -   [1]
50 
 36   Ciclosporin   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [13]
26,
46,
49,
50,
53,
55,
60,
61,
97,
222,
226,
228,
269 
 37   Creapure   -   -   -   -   [1]
50 
 38   Creatine   Creatine   -   -   -   [12]
1,
2,
5,
6,
8,
13,
46,
49,
50,
113,
156,
201 
 39   Cyclophosphamide   Cyclophosphamide   D00287, D07760   -   -   [43]
13,
14,
16,
19,
20,
26,
28,
35,
36,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
52,
56,
60,
61,
62,
65,
66,
84,
85,
93,
96,
162,
164,
172,
222,
224,
265,
274,
283,
284,
285,
288,
326,
331 
 40   Cyclosporine   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [33]
11,
14,
19,
20,
28,
36,
40,
41,
42,
45,
46,
49,
50,
53,
56,
58,
60,
62,
64,
65,
90,
95,
97,
162,
164,
222,
226,
228,
234,
283,
284,
285,
302 
 41   Denosumab   Denosumab   D03684   [1] TNFSF11   [7] Breast cancer, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis   [7]
46,
50,
93,
95,
96,
274,
299 
 42   Etanercept   Etanercept   D00742   [2] LTA, TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [14]
15,
35,
38,
39,
46,
50,
53,
56,
60,
85,
228,
271,
285,
298 
 43   Gamma globulin   -   -   -   -   [2]
15,
50 
 44   Gb-0998   -   -   -   -   [1]
50 
 45   Gevokizumab   Gevokizumab   D09911   [1] IL1B   [40] AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alzheimer disease, Amoebiasis, Antifolate resistance, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Herpes simplex virus 1 infection, Human cytomegalovirus infection, IL-17 signaling pathway, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Influenza A, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Prion diseases, Rheumatoid arthritis, Salmonella infection, Shigellosis, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Tuberculosis, Type I diabetes mellitus, Yersinia infection   [4]
41,
50,
56,
269 
 46   Glucose tablet   -   -   -   -   [1]
50 
 47   Grapefruit   Grapefruit   -   -   -   [5]
6,
46,
50,
83,
97 
 48   H.p. acthar gel   -   -   -   -   [5]
46,
49,
50,
84,
222 
 49   H5g1.1-mab   -   -   -   -   [1]
50 
 50   Hbvaxpro   -   -   -   -   [2]
46,
50 
 51   Human immunoglobulin g   Immune globulin human   -   -   -   [3]
14,
50,
63 
 52   Human normal immunoglobulin   Immune globulin human   -   -   -   [8]
11,
13,
14,
43,
45,
50,
63,
65 
 53   Human normal immunoglobulin (ivig)   Immune globulin human   -   -   -   [2]
50,
65 
 54   Ifn-k   -   -   -   -   [2]
49,
50 
 55   Ifn-kinoid   -   -   -   -   [2]
49,
50 
 56   Ifn-kinoid drug substance   -   -   -   -   [2]
49,
50 
 57   Ifna-kinoid   -   -   -   -   [1]
50 
 58   Ig vena   -   -   -   -   [2]
50,
63 
 59   Ig vena (10g/200ml)   -   -   -   -   [1]
50 
 60   Immunoglobulin (hizentra)   -   -   -   -   [1]
50 
 61   Immunoglobulin g   -   -   -   -   [7]
11,
13,
14,
49,
50,
63,
65 
 62   Immunosuppressive agents   -   -   -   -   [2]
50,
66 
 63   Imo-8400   -   -   -   -   [1]
50 
 64   Imo-8400 dose group 1   -   -   -   -   [1]
50 
 65   Imo-8400 dose group 2   -   -   -   -   [1]
50 
 66   Impact   Topramezone   -   -   -   [7]
6,
13,
46,
50,
96,
97,
299 
 67   Infliximab   Infliximab   D02598   [1] TNF   [61] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Dilated cardiomyopathy (DCM), Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, Pathogenic Escherichia coli infection, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [22]
35,
37,
38,
39,
40,
41,
43,
45,
46,
49,
50,
56,
65,
84,
95,
96,
97,
98,
162,
164,
269,
271 
 68   Influvac   -   -   -   -   [3]
46,
49,
50 
 69   Ivig   Immune globulin human   -   -   -   [12]
11,
13,
14,
17,
18,
50,
51,
63,
65,
85,
164,
296 
 70   Jbt-101   -   -   -   -   [4]
49,
50,
51,
299 
 71   Kzr-616   -   -   -   -   [3]
49,
50,
61 
 72   L0133   -   -   -   -   [1]
50 
 73   Lenabasum   -   -   -   -   [3]
50,
51,
299 
 74   Lenabasum 20 mg   -   -   -   -   [3]
50,
51,
299 
 75   Lenabasum 5 mg   -   -   -   -   [3]
50,
51,
299 
 76   Lipid-lowering agents (artovastatin)   -   -   -   -   [1]
50 
 77   Ly3009104   -   -   -   -   [4]
46,
49,
50,
325 
 78   Mabthera   -   -   -   -   [15]
11,
13,
35,
46,
50,
51,
53,
61,
63,
64,
65,
83,
162,
222,
271 
 79   Medi-545   -   -   -   -   [2]
49,
50 
 80   Medi7734   -   -   -   -   [1]
50 
 81   Methimazole   Methimazole   D00401   [1] TPO   [4] Autoimmune thyroid disease, Metabolic pathways, Thyroid hormone synthesis, Tyrosine metabolism   [1]
50 
 82   Methotrexat   Methotrexate   D00142, D02115   [2] DHFR, DHFR2   [4] Antifolate resistance, Folate biosynthesis, Metabolic pathways, One carbon pool by folate   [3]
13,
46,
50 
 83   Methotrexat lachema 2,5mg   Methotrexate   D00142, D02115   [2] DHFR, DHFR2   [4] Antifolate resistance, Folate biosynthesis, Metabolic pathways, One carbon pool by folate   [1]
50 
 84   Methotrexat lachema 2,5mg tbl.   Methotrexate   D00142, D02115   [2] DHFR, DHFR2   [4] Antifolate resistance, Folate biosynthesis, Metabolic pathways, One carbon pool by folate   [1]
50 
 85   Methotrexat lachema 5 inj. sol   Methotrexate   D00142, D02115   [2] DHFR, DHFR2   [4] Antifolate resistance, Folate biosynthesis, Metabolic pathways, One carbon pool by folate   [1]
50 
 86   Methotrexate   Methotrexate   D00142, D02115   [2] DHFR, DHFR2   [4] Antifolate resistance, Folate biosynthesis, Metabolic pathways, One carbon pool by folate   [33]
11,
13,
19,
34,
35,
41,
42,
43,
44,
45,
46,
49,
50,
51,
53,
55,
56,
60,
62,
65,
84,
93,
96,
97,
162,
164,
172,
256,
271,
284,
285,
326,
331 
 87   Methotrexate lachema 5inj. sol   Methotrexate   D00142, D02115   [2] DHFR, DHFR2   [4] Antifolate resistance, Folate biosynthesis, Metabolic pathways, One carbon pool by folate   [1]
50 
 88   Methylprednisolone   Methylprednisolone   D00407, D00751, D00979, D05000, D05001, D05002   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [36]
2,
13,
25,
26,
35,
38,
39,
40,
41,
42,
43,
45,
46,
49,
50,
51,
60,
63,
64,
65,
66,
83,
84,
86,
96,
97,
145,
164,
220,
222,
224,
271,
283,
284,
285,
296 
 89   Methylprednisoloni natrii succinas   -   -   -   -   [1]
50 
 90   Nifedipine   Nifedipine   D00437   [4] CACNA1C, CACNA1D, CACNA1F, CACNA1S   [34] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy (DCM), Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy (HCM), Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway   [2]
50,
81 
 91   Nivolumab   Nivolumab   D10316   [1] PDCD1   [3] Cell adhesion molecules (CAMs), PD-L1 expression and PD-1 checkpoint pathway in cancer, T cell receptor signaling pathway   [10]
13,
26,
41,
46,
49,
50,
51,
53,
96,
97 
 92   Octagam 10%   -   -   -   -   [3]
50,
63,
65 
 93   Octanorm   -   -   -   -   [2]
50,
65 
 94   Octanorm 16.5%   -   -   -   -   [2]
50,
65 
 95   Orencia   Abatacept   D03203   [2] CD80, CD86   [12] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis   [9]
46,
50,
51,
53,
65,
84,
96,
97,
271 
 96   Pf-06823859   -   -   -   -   [1]
50 
 97   Pirfenidone   Pirfenidone   D01583   [6] CCL2, IL10, IL1A, IL1B, IL6, TNF   [80] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis (ALS), Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, Autoimmune thyroid disease, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease (American trypanosomiasis), Chemokine signaling pathway, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Dilated cardiomyopathy (DCM), EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy (HCM), IL-17 signaling pathway, Inflammatory bowel disease (IBD), Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, MAPK signaling pathway, Malaria, Measles, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease (NAFLD), Osteoclast differentiation, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pertussis, Prion diseases, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Staphylococcus aureus infection, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway   [10]
34,
46,
50,
51,
58,
84,
85,
164,
222,
228 
 98   Placebo   -   -   -   -   [20]
3,
6,
13,
14,
40,
46,
49,
50,
51,
66,
67,
79,
85,
86,
88,
96,
97,
144,
149,
226 
 99   Pneumovax 23   -   -   -   -   [2]
46,
50 
 100   Prednisolone   Prednisolone   D00472, D00980, D00981, D00982, D01239, D01998, D02156, D03301   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [38]
11,
13,
25,
26,
35,
38,
39,
41,
43,
44,
45,
46,
49,
50,
51,
56,
60,
61,
63,
64,
65,
66,
75,
81,
84,
85,
95,
96,
97,
113,
145,
162,
222,
269,
271,
296,
299,
300 
 101   Prednison 5, 20 léciva por. tablet nob   -   -   -   -   [1]
50 
 102   Prednison 5, 20 léciva por. tablet nob.   -   -   -   -   [1]
50 
 103   Prednisone   Prednisone   D00473   [1] NR3C1   [1] Neuroactive ligand-receptor interaction   [43]
2,
11,
13,
14,
26,
35,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
53,
61,
63,
64,
65,
66,
81,
84,
85,
86,
95,
96,
97,
113,
162,
164,
222,
224,
228,
251,
283,
284,
285,
288,
299,
300,
331 
 104   Resunab, ajulemic acid, anabasum   Ajulemic acid   D11312   [1] CNR2   [1] Neuroactive ligand-receptor interaction   [3]
50,
51,
299 
 105   Rituximab   Rituximab   D02994   [1] MS4A1   [1] Hematopoietic cell lineage   [42]
11,
13,
14,
17,
35,
36,
43,
44,
45,
46,
49,
50,
51,
52,
53,
56,
60,
61,
63,
64,
65,
66,
83,
84,
85,
86,
93,
94,
96,
97,
162,
222,
223,
229,
256,
271,
283,
284,
285,
288,
300,
331 
 106   S78989   -   -   -   -   [3]
41,
50,
56 
 107   Same   Ademetionine   D07128   -   -   [15]
6,
14,
22,
43,
44,
46,
47,
49,
50,
60,
84,
93,
96,
97,
172 
 108   Sildenafil   Sildenafil   D02229, D08514   [1] PDE5A   [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway   [15]
6,
46,
50,
51,
85,
86,
113,
210,
211,
212,
225,
226,
278,
294,
299 
 109   Siponimid   -   -   -   -   [1]
50 
 110   Siponimod   Siponimod   D11460   [2] S1PR1, S1PR5   [3] FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway   [2]
13,
50 
 111   Sodium thiosulfate   -   -   -   -   [1]
50 
 112   Solu-medrol inj. pso lqf 40mg   -   -   -   -   [1]
50 
 113   Steroids   -   -   -   -   [7]
46,
50,
51,
63,
66,
96,
97 
 114   Tacrolimus   Tacrolimus   D00107, D08556   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [29]
2,
11,
13,
36,
46,
49,
50,
51,
53,
60,
61,
62,
65,
66,
85,
95,
96,
97,
113,
151,
158,
164,
222,
224,
226,
228,
283,
284,
299 
 115   Tocilizumab   Tocilizumab   D02596   [1] IL6R   [11] Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease (NAFLD), PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor   [16]
2,
13,
40,
41,
43,
46,
50,
51,
53,
54,
55,
86,
107,
266,
271,
331 
 116   Tofacitinib   Tofacitinib   D09970   [4] JAK1, JAK2, JAK3, TYK2   [34] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis   [9]
46,
49,
50,
51,
84,
96,
97,
107,
271 
 117   Ustekinumab   Ustekinumab   D09214   [3] IL12A, IL12B, IL23A   [25] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease (IBD), Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus   [15]
37,
41,
46,
49,
50,
53,
56,
65,
84,
93,
96,
97,
162,
269,
271 
 118   Ustekinumab 6 mg/kg   Ustekinumab   D09214   [3] IL12A, IL12B, IL23A   [25] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease (IBD), Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus   [1]
50 
 119   Ustekinumab 90 mg   Ustekinumab   D09214   [3] IL12A, IL12B, IL23A   [25] African trypanosomiasis, Allograft rejection, Amoebiasis, C-type lectin receptor signaling pathway, Chagas disease (American trypanosomiasis), Cytokine-cytokine receptor interaction, Herpes simplex virus 1 infection, Inflammatory bowel disease (IBD), Influenza A, JAK-STAT signaling pathway, Legionellosis, Leishmaniasis, Malaria, Measles, Pathways in cancer, Pertussis, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus   [3]
50,
93,
96 
 120   Vib7734   -   -   -   -   [4]
49,
50,
51,
53 
 121   Vitamin d   Vitamin d   -   -   -   [18]
13,
19,
41,
46,
49,
50,
68,
93,
95,
96,
98,
179,
222,
228,
235,
274,
298,
299 
 122   Xoma 052   -   -   -   -   [5]
41,
46,
50,
56,
106 
 123   Yellow fever vaccine   Yellow fever vaccine   D06347   -   -   [7]
40,
44,
46,
50,
51,
52,
53 
 124   Yellow fever vaccine (17d)   Yellow fever vaccine   D06347   -   -   [7]
40,
44,
46,
50,
51,
52,
53 

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