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68 / 12,170 descriptions found* Show info (disease name, etc.) on mouse-over.
 No.   Drug (Description in trials)   DrugBank   KEGG DRUG *   KEGG GENES * 
 [Number of genes] 		  KEGG PATHWAY 
 [Number of pathways] 		  Disease ID * 
 [Number of diseases] 
 1   Abp 959   -   -   -   -   [1]
62 
 2   Abp 959 - biosimilar to eculizumab   Eculizumab   D03940   [1] C5   [7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus   [1]
62 
 3   Ach-0144471   -   -   -   -   [3]
62,
222,
223 
 4   Aln-62643   -   -   -   -   [1]
62 
 5   Aln-cc5   -   -   -   -   [2]
62,
109 
 6   Alxn1102   -   -   -   -   [1]
62 
 7   Alxn1103   -   -   -   -   [1]
62 
 8   Alxn1210   -   -   -   -   [2]
62,
109 
 9   Anti-c5 antibody   -   -   -   -   [4]
11,
14,
62,
109 
 10   Anti-thymocyte globulin   -   -   -   -   [18]
11,
13,
14,
36,
40,
41,
42,
45,
46,
49,
51,
60,
62,
65,
164,
283,
284,
285 
 11   Apl-2   -   -   -   -   [5]
61,
62,
66,
222,
223 
 12   Bcd-148   -   -   -   -   [1]
62 
 13   Bryostatin 1   Bryostatin 1   -   -   -   [1]
62 
 14   C5 inh mab, sky59, ro/ch7092230   -   -   -   -   [1]
62 
 15   Campath, chemo and/or tbi allo sct   -   -   -   -   [3]
60,
62,
283 
 16   Coversin   Nomacopan   D11473   [1] C5   [7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus   [2]
62,
109 
 17   Cyclophosphamide   Cyclophosphamide   D00287, D07760   -   -   [43]
13,
14,
16,
19,
20,
26,
28,
35,
36,
40,
41,
42,
43,
44,
45,
46,
49,
50,
51,
52,
56,
60,
61,
62,
65,
66,
84,
85,
93,
96,
162,
164,
172,
222,
224,
265,
274,
283,
284,
285,
288,
326,
331 
 18   Cyclosporin   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [16]
14,
38,
39,
49,
53,
56,
60,
62,
63,
97,
113,
164,
222,
223,
274,
326 
 19   Cyclosporin a   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [11]
14,
38,
39,
49,
53,
56,
60,
62,
63,
113,
164 
 20   Cyclosporin a+glucocorticoids   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [2]
60,
62 
 21   Cyclosporine   Ciclosporin   D00184   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [33]
11,
14,
19,
20,
28,
36,
40,
41,
42,
45,
46,
49,
50,
53,
56,
58,
60,
62,
64,
65,
90,
95,
97,
162,
164,
222,
226,
228,
234,
283,
284,
285,
302 
 22   Cytoreductive regimen followed by a cd34+e- selected allogeneic stem cell transplant   -   -   -   -   [1]
62 
 23   Dextran   Dextran   D00060   -   -   [5]
2,
62,
79,
96,
97 
 24   Eculizumab   Eculizumab   D03940   [1] C5   [7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus   [7]
11,
13,
14,
62,
109,
222,
223 
 25   Fc- and cdr-modified humanised monoclonal antibody against c5   -   -   -   -   [2]
62,
109 
 26   Filgrastim   Filgrastim   D03235   [1] CSF3R   [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer   [25]
2,
6,
13,
25,
26,
28,
34,
35,
40,
41,
42,
45,
46,
49,
51,
60,
62,
65,
96,
113,
164,
283,
284,
285,
331 
 27   Fludarabine   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [17]
13,
28,
36,
46,
49,
51,
60,
61,
62,
65,
85,
96,
164,
283,
284,
285,
326 
 28   Fludarabine phosphate   Fludarabine   D01907, D07966   [1] RRM1   [5] Drug metabolism - other enzymes, Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism   [11]
28,
36,
49,
51,
60,
62,
65,
96,
283,
284,
285 
 29   Glucocorticoids   -   -   -   -   [6]
40,
41,
43,
44,
60,
62 
 30   Human monoclonal antibody directed against complement 5 protein   -   -   -   -   [1]
62 
 31   Iron   Iron   -   -   -   [7]
13,
62,
86,
96,
97,
254,
284 
 32   Iron dextran   Iron dextran   D02141   -   -   [1]
62 
 33   Iron sucrose   Sucrose   D00025   -   -   [3]
62,
96,
97 
 34   Levamisole   Levamisole   D00750, D08114   -   -   [3]
60,
61,
62 
 35   Levamisole+cyclosporin a+glucocorticoids   Levamisole   D00750, D08114   -   -   [2]
60,
62 
 36   Lfg316   -   -   -   -   [1]
62 
 37   Lnp023   -   -   -   -   [3]
62,
66,
222 
 38   Melphalan   Melphalan   D00369   -   -   [14]
11,
13,
14,
19,
20,
28,
60,
62,
65,
96,
164,
234,
284,
285 
 39   Methotrexate   Methotrexate   D00142, D02115   [2] DHFR, DHFR2   [4] Antifolate resistance, Folate biosynthesis, Metabolic pathways, One carbon pool by folate   [33]
11,
13,
19,
34,
35,
41,
42,
43,
44,
45,
46,
49,
50,
51,
53,
55,
56,
60,
62,
65,
84,
93,
96,
97,
162,
164,
172,
256,
271,
284,
285,
326,
331 
 40   Mycophenolate   Mycophenolic acid   D05096   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [33]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
84,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 41   Mycophenolate mofetil   Mycophenolate mofetil   D00752, D05094, D05095   [2] IMPDH1, IMPDH2   [3] Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism   [32]
2,
11,
13,
14,
19,
20,
28,
35,
36,
42,
43,
45,
49,
51,
53,
60,
62,
65,
66,
85,
95,
96,
162,
164,
222,
224,
226,
234,
283,
284,
285,
300 
 42   Myeloablative preparative regimen   -   -   -   -   [3]
62,
65,
284 
 43   Phosphate   Phosphate ion   -   -   -   [29]
2,
3,
11,
12,
13,
28,
36,
46,
49,
51,
53,
60,
62,
65,
70,
78,
81,
83,
90,
96,
97,
164,
235,
256,
283,
284,
285,
286,
299 
 44   Ra101495   -   -   -   -   [1]
62 
 45   Ra101495 sodium   -   -   -   -   [1]
62 
 46   Ravulizumab   Ravulizumab   D11054   [1] C5   [7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus   [3]
11,
62,
109 
 47   Reduced intensity preparative regimen   -   -   -   -   [3]
62,
65,
284 
 48   Reduced toxicity ablative regimen   -   -   -   -   [3]
62,
65,
284 
 49   Regn3918   -   -   -   -   [1]
62 
 50   Ro7112689   -   -   -   -   [1]
62 
 51   Ro7112689/f01   -   -   -   -   [1]
62 
 52   Rva576   -   -   -   -   [3]
62,
109,
162 
 53   Rva576 (coversin)   Nomacopan   D11473   [1] C5   [7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus   [2]
62,
109 
 54   Sargramostim   Sargramostim   D05803   [1] CSF2RA   [4] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, Pathways in cancer   [6]
6,
28,
60,
62,
96,
229 
 55   Sb12 (proposed eculizumab biosimilar)   Eculizumab   D03940   [1] C5   [7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus   [1]
62 
 56   Sirolimus   Sirolimus   D00753   [1] MTOR   [43] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Choline metabolism in cancer, Colorectal cancer, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway   [30]
13,
17,
34,
35,
36,
46,
51,
60,
62,
63,
65,
66,
67,
85,
89,
96,
98,
137,
157,
158,
192,
222,
277,
278,
279,
280,
281,
283,
285,
331 
 57   Soliris   Eculizumab   D03940   [1] C5   [7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus   [7]
11,
13,
14,
62,
109,
222,
223 
 58   Soliris (eculizumab)   Eculizumab   D03940   [1] C5   [7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus   [1]
62 
 59   Sterile normal saline (0.9% nacl)   -   -   -   -   [3]
62,
234,
254 
 60   Study drug - alxn1210   -   -   -   -   [1]
62 
 61   Sucrose   Sucrose   D00025   -   -   [3]
62,
96,
97 
 62   Synthetic 15-amino-acid macrocyclic peptide   -   -   -   -   [1]
62 
 63   Synthetic 15-amino-acid macrocyclic peptide acylated with a ethyleneglycol24 palmitoylated linker   -   -   -   -   [1]
62 
 64   Systematic chemotherapy and antibodies   -   -   -   -   [1]
62 
 65   Systemic chemotherapy and antibodies   -   -   -   -   [2]
62,
326 
 66   Tacrolimus   Tacrolimus   D00107, D08556   [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2   [30] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis (ALS), Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway   [29]
2,
11,
13,
36,
46,
49,
50,
51,
53,
60,
61,
62,
65,
66,
85,
95,
96,
97,
113,
151,
158,
164,
222,
224,
226,
228,
283,
284,
299 
 67   Zilucoplan (ra101495)   -   -   -   -   [2]
11,
62 
 68    lnp023 hydrochloride salt   -   -   -   -   [2]
62,
66 

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