No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * [Number of genes] |
KEGG DRUG * |
DrugBank |
Disease ID * [Number of diseases] |
1 | Adrenergic signaling in cardiomyocytes 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
2 | Aldosterone synthesis and secretion 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
3 | Alzheimer disease 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
4 | Amphetamine addiction 2 genes, 2 drugs (DrugBank), 6 diseases shown |
[2] CACNA1C, CACNA1D |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
5 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
6 | Calcium signaling pathway 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
7 | cAMP signaling pathway 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
8 | Carbohydrate digestion and absorption 1 gene, 2 drugs (DrugBank), 6 diseases shown |
[1] CACNA1D |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
9 | Cardiac muscle contraction 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
10 | Cellular senescence 1 gene, 2 drugs (DrugBank), 6 diseases shown |
[1] CACNA1D |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
11 | cGMP-PKG signaling pathway 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
12 | Cholinergic synapse 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
13 | Circadian entrainment 2 genes, 2 drugs (DrugBank), 6 diseases shown |
[2] CACNA1C, CACNA1D |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
14 | Cortisol synthesis and secretion 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
15 | Cushing syndrome 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
16 | Dilated cardiomyopathy (DCM) 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
17 | Dopaminergic synapse 2 genes, 2 drugs (DrugBank), 6 diseases shown |
[2] CACNA1C, CACNA1D |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
18 | GABAergic synapse 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
19 | Glutamatergic synapse 2 genes, 2 drugs (DrugBank), 6 diseases shown |
[2] CACNA1C, CACNA1D |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
20 | GnRH secretion 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
21 | GnRH signaling pathway 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
22 | Growth hormone synthesis, secretion and action 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
23 | Hypertrophic cardiomyopathy (HCM) 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
24 | Insulin secretion 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
25 | Long-term potentiation 1 gene, 2 drugs (DrugBank), 6 diseases shown |
[1] CACNA1C |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
26 | MAPK signaling pathway 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
27 | Oxytocin signaling pathway 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
28 | Renin secretion 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
29 | Retrograde endocannabinoid signaling 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
30 | Serotonergic synapse 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
31 | Taste transduction 1 gene, 2 drugs (DrugBank), 6 diseases shown |
[1] CACNA1C |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
32 | Tight junction 1 gene, 2 drugs (DrugBank), 6 diseases shown |
[1] CACNA1D |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
33 | Type II diabetes mellitus 2 genes, 2 drugs (DrugBank), 6 diseases shown |
[2] CACNA1C, CACNA1D |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |
34 | Vascular smooth muscle contraction 4 genes, 2 drugs (DrugBank), 6 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
[3] 58, 86, 130 |
D03830 |
D07845 |
D00619 |
Verapamil |
[4] 96, 130, 140, 167 |
D02356 |