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 Target Gene/Pathway 

   e.g. "Sirolimus", "Adalimumab", "MAP2K"

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11 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES
 [Number of genes] 
 KEGG DRUG  DrugBank   Disease ID
 [Number of diseases] 
 1  Cytokine-cytokine receptor interaction 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] IL6R   D02596   Tocilizumab   [16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 2  EGFR tyrosine kinase inhibitor resistance 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] IL6R   D02596   Tocilizumab   [16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 3  Hematopoietic cell lineage 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] IL6R   D02596   Tocilizumab   [16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 4  HIF-1 signaling pathway 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] IL6R   D02596   Tocilizumab   [16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 5  Human cytomegalovirus infection 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] IL6R   D02596   Tocilizumab   [16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 6  JAK-STAT signaling pathway 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] IL6R   D02596   Tocilizumab   [16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 7  Non-alcoholic fatty liver disease (NAFLD) 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] IL6R   D02596   Tocilizumab   [16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 8  Pathways in cancer 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] IL6R   D02596   Tocilizumab   [16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 9  PI3K-Akt signaling pathway 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] IL6R   D02596   Tocilizumab   [16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 10  Th17 cell differentiation 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] IL6R   D02596   Tocilizumab   [16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 
 11  Viral protein interaction with cytokine and cytokine receptor 
 1 gene, 1 drug (DrugBank), 16 diseases shown 
 [1] IL6R   D02596   Tocilizumab   [16] 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 

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