No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * [Number of genes] |
KEGG DRUG * |
DrugBank |
Disease ID * [Number of diseases] |
1 | Adrenergic signaling in cardiomyocytes 9 genes, 5 drugs (DrugBank), 13 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
D02716 |
Pregabalin |
[5] 13, 36, 46, 70, 298 |
[1] SCN5A |
D01450 |
Bupivacaine |
[7] 46, 53, 70, 96, 168, 226, 298 |
D07552 |
D04048 |
Ropivacaine |
[3] 36, 46, 70 |
D08490 |
2 | Alcoholism 5 genes, 2 drugs (DrugBank), 8 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
3 | Aldosterone synthesis and secretion 4 genes, 1 drug (DrugBank), 2 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
4 | Alzheimer disease 9 genes, 3 drugs (DrugBank), 9 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
5 | Amphetamine addiction 7 genes, 3 drugs (DrugBank), 9 diseases shown |
[2] CACNA1C, CACNA1D |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
6 | Amyotrophic lateral sclerosis (ALS) 5 genes, 2 drugs (DrugBank), 8 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
7 | Apelin signaling pathway 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] PDE3B |
D01896 |
Cilostazol |
[2] 51, 70 |
8 | Arachidonic acid metabolism 2 genes, 3 drugs (DrugBank), 18 diseases shown |
[2] PTGS1, PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
[1] PTGS2 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
9 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) 8 genes, 3 drugs (DrugBank), 10 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
D02716 |
Pregabalin |
[5] 13, 36, 46, 70, 298 |
10 | C-type lectin receptor signaling pathway 1 gene, 3 drugs (DrugBank), 18 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
11 | Calcium signaling pathway 11 genes, 7 drugs (DrugBank), 12 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[4] GRIN1, GRIN2A, GRIN2C, GRIN2D |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
[1] HRH1 |
D00300 |
Diphenhydramine |
[5] 49, 51, 70, 86, 256 |
D00669 |
D02419 |
D03285 |
D03360 |
D03854 |
[1] PTGER1 |
D00180 |
Alprostadil |
[2] 51, 70 |
D02705 |
D02722 |
Limaprost |
[1] 70 |
[1] TBXA2R |
D01896 |
Cilostazol |
[2] 51, 70 |
12 | cAMP signaling pathway 11 genes, 4 drugs (DrugBank), 10 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
[2] PDE3A, PDE3B |
D01896 |
Cilostazol |
[2] 51, 70 |
13 | Carbohydrate digestion and absorption 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] CACNA1D |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
14 | Cardiac muscle contraction 8 genes, 3 drugs (DrugBank), 10 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
D02716 |
Pregabalin |
[5] 13, 36, 46, 70, 298 |
15 | Cellular senescence 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] CACNA1D |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
16 | cGMP-PKG signaling pathway 10 genes, 4 drugs (DrugBank), 17 diseases shown |
[3] ADRA2A, ADRA2B, ADRA2C |
D00514 |
Dexmedetomidine |
[11] 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
D01205 |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[1] OPRD1 |
D03783 |
Oxycodone |
[7] 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
[2] PDE3A, PDE3B |
D01896 |
Cilostazol |
[2] 51, 70 |
17 | Chemical carcinogenesis 1 gene, 3 drugs (DrugBank), 18 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
18 | Cholinergic synapse 4 genes, 1 drug (DrugBank), 2 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
19 | Circadian entrainment 7 genes, 3 drugs (DrugBank), 9 diseases shown |
[2] CACNA1C, CACNA1D |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
20 | Cocaine addiction 5 genes, 2 drugs (DrugBank), 8 diseases shown |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
21 | Complement and coagulation cascades 2 genes, 3 drugs (DrugBank), 15 diseases shown |
[1] PLG |
D00160 |
Aminocaproic Acid |
[1] 70 |
D01136 |
Tranexamic acid |
[5] 46, 70, 215, 227, 288 |
[1] SERPINC1 |
D07510 |
Heparin |
[11] 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 |
22 | Cortisol synthesis and secretion 4 genes, 1 drug (DrugBank), 2 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
23 | Cushing syndrome 4 genes, 1 drug (DrugBank), 2 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
24 | Cytokine-cytokine receptor interaction 1 gene, 1 drug (DrugBank), 9 diseases shown |
[1] EPOR |
D03231 |
Erythropoietin |
[9] 2, 6, 13, 22, 46, 47, 70, 95, 96 |
25 | Dilated cardiomyopathy (DCM) 8 genes, 3 drugs (DrugBank), 10 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
D02716 |
Pregabalin |
[5] 13, 36, 46, 70, 298 |
26 | Dopaminergic synapse 5 genes, 5 drugs (DrugBank), 16 diseases shown |
[2] CACNA1C, CACNA1D |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[2] GRIN2A, GRIN2B |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
[1] SCN1A |
D01450 |
Bupivacaine |
[7] 46, 53, 70, 96, 168, 226, 298 |
D07552 |
D04048 |
Ropivacaine |
[3] 36, 46, 70 |
D08490 |
27 | Endocrine and other factor-regulated calcium reabsorption 1 gene, 2 drugs (DrugBank), 8 diseases shown |
[1] PTH1R |
D05364 |
Parathyroid hormone |
[3] 70, 235, 326 |
D06078 |
Teriparatide |
[7] 46, 65, 68, 70, 71, 235, 274 |
28 | Estrogen signaling pathway 1 gene, 7 drugs (DrugBank), 13 diseases shown |
[1] OPRM1 |
D00836 |
Buprenorphine |
[2] 46, 70 |
D07132 |
D00320 |
Fentanyl |
[5] 46, 70, 85, 215, 231 |
D01399 |
D00842 |
Morphine |
[4] 36, 46, 70, 86 |
D02271 |
D08233 |
D03783 |
Oxycodone |
[7] 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
D08323 |
Oxymorphone |
[1] 70 |
D01177 |
Remifentanil |
[2] 6, 70 |
D08473 |
D01355 |
Tramadol |
[5] 46, 70, 78, 226, 271 |
D08623 |
29 | GABAergic synapse 21 genes, 3 drugs (DrugBank), 13 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
[1] SLC6A1 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
30 | Glucagon signaling pathway 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] PDE3B |
D01896 |
Cilostazol |
[2] 51, 70 |
31 | Glutamatergic synapse 7 genes, 3 drugs (DrugBank), 9 diseases shown |
[2] CACNA1C, CACNA1D |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
32 | GnRH secretion 4 genes, 1 drug (DrugBank), 2 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
33 | GnRH signaling pathway 4 genes, 1 drug (DrugBank), 2 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
34 | Growth hormone synthesis, secretion and action 4 genes, 1 drug (DrugBank), 2 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
35 | Hematopoietic cell lineage 1 gene, 1 drug (DrugBank), 9 diseases shown |
[1] EPOR |
D03231 |
Erythropoietin |
[9] 2, 6, 13, 22, 46, 47, 70, 95, 96 |
36 | Human cytomegalovirus infection 2 genes, 5 drugs (DrugBank), 18 diseases shown |
[1] PTGER1 |
D00180 |
Alprostadil |
[2] 51, 70 |
D02705 |
D02722 |
Limaprost |
[1] 70 |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
37 | Human papillomavirus infection 1 gene, 3 drugs (DrugBank), 18 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
38 | Huntington disease 2 genes, 2 drugs (DrugBank), 8 diseases shown |
[2] GRIN1, GRIN2B |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
39 | Hypertrophic cardiomyopathy (HCM) 8 genes, 3 drugs (DrugBank), 10 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
D02716 |
Pregabalin |
[5] 13, 36, 46, 70, 298 |
40 | IL-17 signaling pathway 1 gene, 3 drugs (DrugBank), 18 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
41 | Inflammatory mediator regulation of TRP channels 1 gene, 1 drug (DrugBank), 5 diseases shown |
[1] HRH1 |
D00300 |
Diphenhydramine |
[5] 49, 51, 70, 86, 256 |
D00669 |
D02419 |
D03285 |
D03360 |
D03854 |
42 | Influenza A 1 gene, 2 drugs (DrugBank), 5 diseases shown |
[1] PLG |
D00160 |
Aminocaproic Acid |
[1] 70 |
D01136 |
Tranexamic acid |
[5] 46, 70, 215, 227, 288 |
43 | Insulin secretion 5 genes, 2 drugs (DrugBank), 14 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[1] SNAP25 |
D00783 |
Botulinum toxin type A |
[13] 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226 |
44 | Insulin signaling pathway 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] PDE3B |
D01896 |
Cilostazol |
[2] 51, 70 |
45 | JAK-STAT signaling pathway 1 gene, 1 drug (DrugBank), 9 diseases shown |
[1] EPOR |
D03231 |
Erythropoietin |
[9] 2, 6, 13, 22, 46, 47, 70, 95, 96 |
46 | Kaposi sarcoma-associated herpesvirus infection 1 gene, 3 drugs (DrugBank), 18 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
47 | Leishmaniasis 1 gene, 3 drugs (DrugBank), 18 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
48 | Long-term potentiation 6 genes, 3 drugs (DrugBank), 9 diseases shown |
[1] CACNA1C |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
49 | MAPK signaling pathway 8 genes, 3 drugs (DrugBank), 10 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
D02716 |
Pregabalin |
[5] 13, 36, 46, 70, 298 |
50 | Metabolic pathways 4 genes, 4 drugs (DrugBank), 18 diseases shown |
[2] PDE3A, PDE3B |
D01896 |
Cilostazol |
[2] 51, 70 |
[2] PTGS1, PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
[1] PTGS2 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
51 | MicroRNAs in cancer 1 gene, 3 drugs (DrugBank), 18 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
52 | Morphine addiction 19 genes, 9 drugs (DrugBank), 18 diseases shown |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
[1] OPRM1 |
D00836 |
Buprenorphine |
[2] 46, 70 |
D07132 |
D00320 |
Fentanyl |
[5] 46, 70, 85, 215, 231 |
D01399 |
D00842 |
Morphine |
[4] 36, 46, 70, 86 |
D02271 |
D08233 |
D03783 |
Oxycodone |
[7] 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
D08323 |
Oxymorphone |
[1] 70 |
D01177 |
Remifentanil |
[2] 6, 70 |
D08473 |
D01355 |
Tramadol |
[5] 46, 70, 78, 226, 271 |
D08623 |
[2] PDE3A, PDE3B |
D01896 |
Cilostazol |
[2] 51, 70 |
53 | Neuroactive ligand-receptor interaction 35 genes, 22 drugs (DrugBank), 58 diseases shown |
[3] ADRA2A, ADRA2B, ADRA2C |
D00514 |
Dexmedetomidine |
[11] 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
D01205 |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
[1] HRH1 |
D00300 |
Diphenhydramine |
[5] 49, 51, 70, 86, 256 |
D00669 |
D02419 |
D03285 |
D03360 |
D03854 |
[1] NR3C1 |
D00292 |
Dexamethasone |
[20] 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299 |
D00975 |
D01510 |
D01615 |
D01632 |
D01948 |
D02174 |
D02591 |
D02592 |
D00385 |
Triamcinolone |
[18] 6, 10, 13, 35, 40, 41, 42, 43, 44, 45, 46, 56, 70, 90, 96, 97, 226, 298 |
D00983 |
D00984 |
D00985 |
D06216 |
[3] OPRD1, OPRK1, OPRM1 |
D03783 |
Oxycodone |
[7] 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
[2] OPRK1, OPRM1 |
D00836 |
Buprenorphine |
[2] 46, 70 |
D07132 |
[1] OPRM1 |
D00320 |
Fentanyl |
[5] 46, 70, 85, 215, 231 |
D01399 |
D00842 |
Morphine |
[4] 36, 46, 70, 86 |
D02271 |
D08233 |
D08323 |
Oxymorphone |
[1] 70 |
D01177 |
Remifentanil |
[2] 6, 70 |
D08473 |
D01355 |
Tramadol |
[5] 46, 70, 78, 226, 271 |
D08623 |
[1] PLG |
D00160 |
Aminocaproic Acid |
[1] 70 |
D01136 |
Tranexamic acid |
[5] 46, 70, 215, 227, 288 |
[1] PTGER1 |
D00180 |
Alprostadil |
[2] 51, 70 |
D02705 |
D02722 |
Limaprost |
[1] 70 |
[1] PTGIR |
D09994 |
Selexipag |
[5] 51, 70, 84, 86, 88 |
[1] PTH1R |
D06078 |
Teriparatide |
[7] 46, 65, 68, 70, 71, 235, 274 |
[2] PTH1R, PTH2R |
D05364 |
Parathyroid hormone |
[3] 70, 235, 326 |
[1] TBXA2R |
D01896 |
Cilostazol |
[2] 51, 70 |
54 | NF-kappa B signaling pathway 1 gene, 3 drugs (DrugBank), 18 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
55 | Nicotine addiction 21 genes, 3 drugs (DrugBank), 14 diseases shown |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
56 | Ovarian steroidogenesis 1 gene, 3 drugs (DrugBank), 18 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
57 | Oxytocin signaling pathway 9 genes, 6 drugs (DrugBank), 22 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
D02716 |
Pregabalin |
[5] 13, 36, 46, 70, 298 |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
58 | Parathyroid hormone synthesis, secretion and action 1 gene, 2 drugs (DrugBank), 8 diseases shown |
[1] PTH1R |
D05364 |
Parathyroid hormone |
[3] 70, 235, 326 |
D06078 |
Teriparatide |
[7] 46, 65, 68, 70, 71, 235, 274 |
59 | Pathways in cancer 3 genes, 6 drugs (DrugBank), 21 diseases shown |
[1] EPOR |
D03231 |
Erythropoietin |
[9] 2, 6, 13, 22, 46, 47, 70, 95, 96 |
[1] PTGER1 |
D00180 |
Alprostadil |
[2] 51, 70 |
D02705 |
D02722 |
Limaprost |
[1] 70 |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
60 | PI3K-Akt signaling pathway 1 gene, 1 drug (DrugBank), 9 diseases shown |
[1] EPOR |
D03231 |
Erythropoietin |
[9] 2, 6, 13, 22, 46, 47, 70, 95, 96 |
61 | Platelet activation 3 genes, 4 drugs (DrugBank), 16 diseases shown |
[1] PTGIR |
D09994 |
Selexipag |
[5] 51, 70, 84, 86, 88 |
[1] PTGS1 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
[1] TBXA2R |
D01896 |
Cilostazol |
[2] 51, 70 |
62 | Progesterone-mediated oocyte maturation 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] PDE3B |
D01896 |
Cilostazol |
[2] 51, 70 |
63 | Purine metabolism 2 genes, 1 drug (DrugBank), 2 diseases shown |
[2] PDE3A, PDE3B |
D01896 |
Cilostazol |
[2] 51, 70 |
64 | Rap1 signaling pathway 3 genes, 2 drugs (DrugBank), 8 diseases shown |
[3] GRIN1, GRIN2A, GRIN2B |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
65 | Ras signaling pathway 3 genes, 2 drugs (DrugBank), 8 diseases shown |
[3] GRIN1, GRIN2A, GRIN2B |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
66 | Regulation of lipolysis in adipocytes 3 genes, 4 drugs (DrugBank), 18 diseases shown |
[1] PDE3B |
D01896 |
Cilostazol |
[2] 51, 70 |
[2] PTGS1, PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
[1] PTGS2 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
67 | Renin secretion 6 genes, 2 drugs (DrugBank), 3 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[2] PDE3A, PDE3B |
D01896 |
Cilostazol |
[2] 51, 70 |
68 | Retrograde endocannabinoid signaling 21 genes, 5 drugs (DrugBank), 20 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
69 | Serotonergic synapse 9 genes, 5 drugs (DrugBank), 20 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[3] GABRB1, GABRB2, GABRB3 |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
[2] PTGS1, PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
[1] PTGS2 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
70 | Small cell lung cancer 1 gene, 3 drugs (DrugBank), 18 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
71 | Sphingolipid signaling pathway 1 gene, 1 drug (DrugBank), 7 diseases shown |
[1] OPRD1 |
D03783 |
Oxycodone |
[7] 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
72 | Staphylococcus aureus infection 1 gene, 2 drugs (DrugBank), 5 diseases shown |
[1] PLG |
D00160 |
Aminocaproic Acid |
[1] 70 |
D01136 |
Tranexamic acid |
[5] 46, 70, 215, 227, 288 |
73 | Synaptic vesicle cycle 2 genes, 2 drugs (DrugBank), 16 diseases shown |
[1] SLC6A1 |
D00332 |
Gabapentin |
[7] 6, 13, 19, 70, 97, 226, 298 |
[1] SNAP25 |
D00783 |
Botulinum toxin type A |
[13] 2, 5, 6, 7, 13, 15, 17, 36, 51, 70, 113, 149, 226 |
74 | Systemic lupus erythematosus 2 genes, 2 drugs (DrugBank), 8 diseases shown |
[2] GRIN2A, GRIN2B |
D07283 |
Esketamine |
[3] 2, 4, 70 |
D00711 |
Ketamine |
[6] 6, 13, 70, 113, 156, 215 |
D08098 |
75 | Taste transduction 10 genes, 4 drugs (DrugBank), 15 diseases shown |
[1] CACNA1C |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 |
D00550 |
Midazolam |
[10] 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
[3] SCN2A, SCN3A, SCN9A |
D01450 |
Bupivacaine |
[7] 46, 53, 70, 96, 168, 226, 298 |
D07552 |
D04048 |
Ropivacaine |
[3] 36, 46, 70 |
D08490 |
76 | Tight junction 1 gene, 1 drug (DrugBank), 2 diseases shown |
[1] CACNA1D |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
77 | TNF signaling pathway 1 gene, 3 drugs (DrugBank), 18 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |
78 | Type II diabetes mellitus 2 genes, 1 drug (DrugBank), 2 diseases shown |
[2] CACNA1C, CACNA1D |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
79 | Vascular smooth muscle contraction 5 genes, 2 drugs (DrugBank), 5 diseases shown |
[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00617 |
Nicardipine |
[2] 70, 86 |
D08270 |
[1] PTGIR |
D09994 |
Selexipag |
[5] 51, 70, 84, 86, 88 |
80 | VEGF signaling pathway 1 gene, 3 drugs (DrugBank), 18 diseases shown |
[1] PTGS2 |
D00217 |
Acetaminophen |
[13] 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00567 |
Celecoxib |
[9] 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00813 |
Ketorolac |
[2] 70, 226 |
D08104 |