Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1100 mg ELX (VX-445) / 50 mg TEZ / 75 mg IVA FDC----[1] 299
2100 mg ELX /50 mg TEZ /75 mg IVA FDC----[1] 299
3100 mg ELX/50 mg TEZ /75 mg IVA FDC----[1] 299
4100 mg ELX/50 mg TEZ/75 mg IVA fixed dose combination----[1] 299
5100 mg VX-445 /50 mg TEZ/75 mg IVA FDC----[1] 299
6100 mg VX-445/50 mg TEZ /75 mg IVA FDC----[1] 299
7100-mg ELX (VX-445) / 50-mg TEZ / 75-mg IVA FDC----[1] 299
8100-mg ELX (VX-455) / 50-mg TEZ / 75-mg IVA FDC----[1] 299
9100-mg ELX / 50-mg TEZ / 75 -mg IVA FDC----[1] 299
10100-mg VX-445 / 50-mg TEZ / 75- mg IVA FDC----[1] 299
11100-mg VX-445 / 50-mg TEZ / 75-mg IVA FDC----[1] 299
12100-mg VX-445 /50-mg TEZ/75-mg----[1] 299
13100-mg VX-445/50-mg TEZ/75-mg IVA FDC----[1] 299
14100g ELX / 50mg TEZ / 75mg IVA----[1] 299
15100mg ELX/50mg TEZ /75mg IVA----[1] 299
16100mg VX-445/50mg TEZ /75mg IVA FDC----[1] 299
1756/104/75-C----[1] 50
1875----[1] 6
1975 mg Ontamalimab[1] Ontamalimab---[2] 96, 97
2075-mg IVACAFTOR[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
21750 mg metformin and 7.5 g L-citrulline daily p.o.[2] Citrulline,
Metformin (Synonym: Metformin ER 750 mg)		[1] D04966 [2] PRKAA1,
PRKAA2 💬		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[1] 113
22750mg mesalazine pellets[1] Mesalazine[1] D00377 --[1] 97
2375mg CXA-10[1] CXA-10---[1] 86
2475mg SHP647 (PF-00547659)----[1] 97
25AIN457, 75 mg----[1] 271
26Atacicept 75 mg[1] Atacicept[1] D09704 [2] TNFSF13,
TNFSF13B 💬		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[3] 13, 49, 66
27Atacicept 75 milligram (mg)[1] Atacicept[1] D09704 [2] TNFSF13,
TNFSF13B 💬		[4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[1] 49
28AZLI 75 mg three times a day (TID)----[1] 299
29AZLI 75 mg three times daily (TID)----[1] 299
30AZLI 75 mg two times a day (BID)/ three times a day (TID)----[1] 299
31AZLI 75 mg two times a day (BID)/three times a day (TID)----[1] 299
32Betaloc ZOK 25, 23,75 mg----[1] 113
33BMS-986004 75 mg IV----[1] 63
34Catapresan 75----[1] 78
35Catapresan 75, Tabletten----[1] 65
36Cayston 75 mg Pulver und Lösungsmittel zur Herstellung einer Lösung für einen Vernebler[1] Aztreonam[1] D00240 --[1] 299
37CAYSTON aztreonam 75 mg powder and solvent for nebuliser solution[1] Aztreonam[1] D00240 --[1] 299
38Certican 0,75mg[1] Everolimus[1] D02714 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[1] 228
39Certican 0,75mg Tabletten[1] Everolimus[1] D02714 [1] MTOR 💬[51] AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬[1] 228
40Cohort 2 0.75g----[1] 240
41Colistimethate 75 mg inhaled two times daily[1] Colistimethate---[1] 299
42Continuous oxygen
(Synonym: OXYGEN/HELIUM 25/75)		[1] Oxygen (Synonym: Oxygen/Helium 25/75)[1] D00003 (Name: OXYGEN/HELIUM 25/75)--[1] 90
43CVL-751----[1] 6
44Depot leuprolide acetate 3.75 mg[2] Acetate,
Leuprolide		---[1] 51
45Dulaglutide 0.75Mg/0.5Ml Inj Pen[1] Dulaglutide[1] D09889 [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 299
46Ebetrex 15 mg = 0,75 ml, oplossing voor injectie in voorgevulde injectiespuit 20 mg/ml----[1] 96
47Efexor XL 75 mg----[1] 46
48Efexor XL 75 mg (venlafaxine)[1] Venlafaxine[1] D08670 [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[1] 46
49Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 ,
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
50Helium / oxygen mixed gas inhalation therapy
(Synonym: OXYGEN/HELIUM 25/75)		[2] Helium,
Oxygen (Synonym: Oxygen/Helium 25/75)		[2] D00003 (Name: OXYGEN/HELIUM 25/75),
D04420 		--[1] 330
51IncobotulinumtoxinA (75 Units)[1] Botulinum toxin type A[1] D00783 [1] SNAP25 💬[2] Insulin secretion, Synaptic vesicle cycle 💬[1] 6
52Inhaled nitric oxide 75 mcg/kg IBW/hr[1] Nitric Oxide[1] D00074 --[2] 85, 86
53INM-755----[1] 36
54INM-755 (cannabinol) cream[1] Cannabinol---[1] 36
55Irbesartan tablets (NDA 020 757)[1] Irbesartan[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 66
56Ivacaftor 25 mg/75 mg[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
57Ivacaftor 75 mg[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
58Ivacaftor 75 mg/150 mg[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
59IVACAFTOR 75mg[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
60Jaktinib Dihydrochloride Monohydrate 50mg BID and Mimic tablets of jakitinib hydrochloride 75mg BID and Acetylcysteine Effervescent Tablets[1] Acetylcysteine[1] D00221 --[1] 85
61Jaktinib Dihydrochloride Monohydrate 75mg BID and Mimic tablets of jakitinib hydrochloride 50mg BID and Acetylcysteine Effervescent Tablets[1] Acetylcysteine[1] D00221 --[1] 85
62JNJ-54781532 75 mg once daily----[1] 97
63JNJ-54781532 75 mg twice daily----[1] 97
64Leuprorelin Acetate 3.75mg Injection[2] Acetate,
Leuprolide		---[1] 76
65Levodopa 75 mg A CAP[1] Levodopa[1] D00059 [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 6
66LIQ861 75 µg----[1] 86
67Luphere depot 3.75mg(Leuprolide acetate 3.75mg)[2] Acetate,
Leuprolide		---[1] 76
68M2951 75 mg QD----[1] 46
69Macitentan 75 mg[1] Macitentan[1] D10135 [2] EDNRA,
EDNRB 💬		[9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 86
70Medical Air vs Oxygen
(Synonym: OXYGEN/HELIUM 25/75)		[2] Medical air,
Oxygen (Synonym: Oxygen/Helium 25/75)		[1] D00003 (Name: OXYGEN/HELIUM 25/75)--[1] 193
71Medical Grade Oxygen
(Synonym: OXYGEN/HELIUM 25/75)		[1] Oxygen (Synonym: Oxygen/Helium 25/75)[1] D00003 (Name: OXYGEN/HELIUM 25/75)--[1] 299
72MetoHEXAL® Succ ® 23,75 mg Retardtabletten----[1] 113
73Nitric Oxide plus Oxygen
(Synonym: OXYGEN/HELIUM 25/75)		[2] Nitric Oxide,
Oxygen (Synonym: Oxygen/Helium 25/75)		[2] D00003 (Name: OXYGEN/HELIUM 25/75),
D00074 		--[1] 86
74Oral Glucose Tolerance test (75g 2-hour)[1] Dextrose, unspecified form (Synonym: 75gm Glucose Tolerance Drink)---[1] 299
75Over-encapsulated 75 mg Irbesartan Tablets[1] Irbesartan[1] D00523 [1] AGTR1 💬[16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 222
76Oxygen
(Synonym: OXYGEN/HELIUM 25/75)		[1] Oxygen (Synonym: Oxygen/Helium 25/75)[1] D00003 (Name: OXYGEN/HELIUM 25/75)--[13] 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330
77Oxygen 40 %
(Synonym: OXYGEN/HELIUM 25/75)		[1] Oxygen (Synonym: Oxygen/Helium 25/75)[1] D00003 (Name: OXYGEN/HELIUM 25/75)--[1] 85
78Oxygen supplementation
(Synonym: OXYGEN/HELIUM 25/75)		[1] Oxygen (Synonym: Oxygen/Helium 25/75)[1] D00003 (Name: OXYGEN/HELIUM 25/75)--[1] 86
79Oxygen, liquid
(Synonym: OXYGEN/HELIUM 25/75)		[1] Oxygen (Synonym: Oxygen/Helium 25/75)[1] D00003 (Name: OXYGEN/HELIUM 25/75)--[2] 86, 88
80Oxygen-15 Water
(Synonym: OXYGEN/HELIUM 25/75)		[2] Oxygen (Synonym: Oxygen/Helium 25/75),
Water (Synonym: GFA First Aid 75 Person Metal Case)		[2] D00001 ,
D00003 (Name: OXYGEN/HELIUM 25/75)		--[1] 6
81P2B001 once daily (pramipexole 0.3 mg / rasagiline 0.75 mg),[2] Pramipexole,
Rasagiline		[3] D05575 ,
D08469 ,
D10829 		[4] DRD2,
DRD3,
DRD4,
MAOB 💬		[18] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Gap junction, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
82P2B001 once daily (pramipexole 0.6 mg / rasagiline 0.75 mg),[2] Pramipexole,
Rasagiline		[3] D05575 ,
D08469 ,
D10829 		[4] DRD2,
DRD3,
DRD4,
MAOB 💬		[18] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Gap junction, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬[1] 6
83P38 Inhibitor (4) 75mg----[1] 46
84Perfluorinated gas/oxygen mixture
(Synonym: OXYGEN/HELIUM 25/75)		[1] Oxygen (Synonym: Oxygen/Helium 25/75)[1] D00003 (Name: OXYGEN/HELIUM 25/75)--[1] 299
85Pregabalin 75mg[1] Pregabalin (Synonym: Pregabalin-75)[1] D02716 [4] CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		[7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬[1] 70
86RANEXA - 750 MG - COMPRESSA A RILASCIO PROLUNGATO- USO ORALE - BLISTER (PVC/PVDC/ALLUMINIO) 60 COMPRESSE[1] Ranolazine[1] D05700 --[1] 58
87RANEXA*60CPR 750MG R.P.[1] Ranolazine[1] D05700 --[1] 58
88Ranolazine 750 mg PR tablets[1] Ranolazine[1] D05700 --[1] 58
89Ranolazine PR (prolonged-release) 500 mg 1 tablet bis in die and 750 mg 1 tablet bis in die[1] Ranolazine[1] D05700 --[1] 58
90Revolade 75 mg[1] Eltrombopag---[1] 60
91RhuDex 25 mg (31.75 mg RhuDex choline salt) granules[1] Choline (Synonym: Mega-vim 75 With Beta-carotene - Tablets)[1] D07690 --[1] 93
92RO 487-7533----[1] 46
93Ro 487-7533/F01----[3] 46, 107, 271
94Ro 487-7533/F10----[2] 46, 107
95Ro 487-7533/F10-02----[1] 46
96Ro 487-7533/F10-04----[4] 41, 46, 51, 107
97Ro 491-7523/F18----[1] 206
98Ro 491-7523/F19----[1] 206
99Ro487-7533----[1] 46
100RO487-7533/F01-F05----[1] 46
101RO487-7533/F10-04----[2] 46, 51
102Secukinumab (75 mg)[1] Secukinumab[1] D09967 [1] IL17A 💬[6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[1] 271
103Secukinumab 75 mg/0.5 ml Solution for injection[1] Secukinumab[1] D09967 [1] IL17A 💬[6] Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬[1] 271
104Standard analgesia use [Oxygen]
(Synonym: OXYGEN/HELIUM 25/75)		[1] Oxygen (Synonym: Oxygen/Helium 25/75)[1] D00003 (Name: OXYGEN/HELIUM 25/75)--[1] 70
105SUSPENSION CONTAINING 7500 EMBRYONATED VIABLE TRICHURIS SUIS OVA/15ML----[1] 97
106Suspension containing 7500 embryonated, viable Trichuris suis ova (TSO)/15ml----[1] 96
107Suspension of 7500 embryonated, viable TSO/15ml----[1] 96
108TAK-755----[1] 64
109TAK-755 or BAX930 or SHP655----[1] 64
110TAK-755 orBAX930 or SHP655----[1] 64
111Trulicity 0,75 mg injekcný roztok naplnený v injekcnom pere[1] Dulaglutide[1] D09889 [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 13
112Trulicity 0,75 mg injekcný roztok naplnený v injekcnom pere.[1] Dulaglutide[1] D09889 [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[1] 13
113TSO 7500----[1] 96
114Vamorolone 0.75 mg/day/day[1] Vamorolone[1] D11000 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 113
115Vamorolone 0.75 mg/kg/day[1] Vamorolone[1] D11000 [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[1] 113
116Veltuzumab solution 75mg/ml[1] Veltuzumab[1] D09031 [1] MS4A1 💬[1] Hematopoietic cell lineage 💬[1] 46
117VX-661/ivacaftor 50 mg/ 75 mg[1] Ivacaftor[1] D09916 [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299