Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
12S,4R-(-)-ketoconazole[1] Ketoconazole[1] D00351 (Name: Ketoconazole)[1] CYP17A1 💬[6] Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬[1] 75
22S,4R-(-)-ketoconazole, levoketoconazole[2] Ketoconazole,
Levoketoconazole		[2] D00351 (Name: Ketoconazole),
D10950 		[3] CYP11A1,
CYP11B1,
CYP17A1 💬		[7] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬[1] 75
3Dimebon + Ketoconazole[2] Ketoconazole,
Latrepirdine		[2] D00351 (Name: Ketoconazole),
D09917 		[7] ACHE,
CYP17A1,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬		[28] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Cortisol synthesis and secretion, Cushing syndrome, Dopaminergic synapse, Glutamatergic synapse, Glycerophospholipid metabolism, Huntington disease, Long-term potentiation, Metabolic pathways, Neuroactive ligand-receptor interaction, Nicotine addiction, Ovarian steroidogenesis, Pathways of neurodegeneration - multiple diseases, Prion disease, Prolactin signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Steroid hormone biosynthesis, Systemic lupus erythematosus, cAMP signaling pathway 💬[1] 8
4Ketoconazole[1] Ketoconazole[1] D00351 (Name: Ketoconazole)[1] CYP17A1 💬[6] Cortisol synthesis and secretion, Cushing syndrome, Metabolic pathways, Ovarian steroidogenesis, Prolactin signaling pathway, Steroid hormone biosynthesis 💬[3] 8, 13, 75