Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1150-mg IVACAFTOR[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
2150mg IVACAFTOR[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
375-mg IVACAFTOR[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
4CF patients with a G551D mutation and treated with Ivacaftor[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
5Deuterated Ivacaftor[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
6Elexacaftor / Ivacaftor / Tezacaftor[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 (Name: Ivacaftor),
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
7Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 (Name: Ivacaftor),
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
8Elexacaftor-tezacaftor-ivacaftor exposure[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 (Name: Ivacaftor),
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
9Elexacaftor/tezacaftor/ivacaftor[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 (Name: Ivacaftor),
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
10IVACAFTOR[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
11Ivacaftor (proposed INN)[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
12Ivacaftor 125mg tablet[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
13Ivacaftor 150 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
14Ivacaftor 150 mg or 250 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
15Ivacaftor 25 mg/75 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
16IVACAFTOR 59,5mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
17IVACAFTOR 59.5mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
18Ivacaftor 75 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
19Ivacaftor 75 mg/150 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
20IVACAFTOR 75mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
21Ivacaftor Exposed[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
22Ivacaftor or elexacaftor/tezacaftor/ivacaftor[3] Elexacaftor,
Ivacaftor,
Tezacaftor		[3] D09916 (Name: Ivacaftor),
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
23Ivacaftor+lumacaftor[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
24Ivacaftor/Ataluren[2] Ataluren,
Ivacaftor		[2] D09323 ,
D09916 (Name: Ivacaftor)		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
25Ivacaftor/Kalydeco[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
26Ivacaftor/Trikafta[2] Ivacaftor,
Tezacaftor		[2] D09916 (Name: Ivacaftor),
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
27Lumacaftor / ivacaftor[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
28Lumacaftor plus Ivacaftor[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
29Lumacaftor Plus Ivacaftor Combination[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
30Lumacaftor, Ivacaftor Drug Combination[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
31Lumacaftor-ivacaftor[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
32Lumacaftor-Ivacaftor treatment[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
33Lumacaftor/Ivacaftor[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
34Lumacaftor/ivacaftor 100mg/125mg tablets[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
35Lumacaftor/ivacaftor 200mg/125mg[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
36Lumacaftor/ivacaftor 200mg/125mg tablets[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
37Lumacaftor/ivacaftor 200mg/83mg tablet[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
38Orkambi: contains lumacaftor and ivacaftor[2] Ivacaftor,
Lumacaftor		[2] D09916 (Name: Ivacaftor),
D10134 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
39Tezacaftor/Ivacaftor[2] Ivacaftor,
Tezacaftor		[2] D09916 (Name: Ivacaftor),
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
40Tezacaftor/Ivacaftor + Ivacaftor[2] Ivacaftor,
Tezacaftor		[2] D09916 (Name: Ivacaftor),
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
41Tezacaftor/Ivacaftor 100mg/150mg[2] Ivacaftor,
Tezacaftor		[2] D09916 (Name: Ivacaftor),
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
42Tezacaftor/Ivacaftor/100mg/150mg[2] Ivacaftor,
Tezacaftor		[2] D09916 (Name: Ivacaftor),
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
43Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor[4] Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor		[4] D09916 (Name: Ivacaftor),
D10134 ,
D11041 ,
D11507 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
44VX-659/Tezacaftor/Ivacaftor[3] Ivacaftor,
Tezacaftor,
VX-659		[2] D09916 (Name: Ivacaftor),
D11041 		[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
45VX-661 Plus Ivacaftor Combination[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
46VX-661/Ivacaftor[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
47VX-661/ivacaftor (VX-770) 100mg/150 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
48VX-661/ivacaftor 100 mg/ 150 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
49VX-661/ivacaftor 100mg/150 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
50VX-661/ivacaftor 100mg/150mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
51VX-661/ivacaftor 50 mg/ 75 mg[1] Ivacaftor[1] D09916 (Name: Ivacaftor)[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299