Drug Description in Trials / DrugBank / KEGG DRUG


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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1150-mg IVACAFTOR
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
2150mg IVACAFTOR
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
375-mg IVACAFTOR
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
4CF patients with a G551D mutation and treated with Ivacaftor
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
5Deuterated Ivacaftor
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
6Elexacaftor / Ivacaftor / Tezacaftor
(Synonym: Kalydeco (TN))
[3] Elexacaftor,
Ivacaftor (Synonym: Kalydeco),
Tezacaftor
[3] D09916 (Name: Kalydeco (TN)),
D11041 ,
D11507
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
7Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening
(Synonym: Kalydeco (TN))
[3] Elexacaftor,
Ivacaftor (Synonym: Kalydeco),
Tezacaftor
[3] D09916 (Name: Kalydeco (TN)),
D11041 ,
D11507
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
8Elexacaftor-tezacaftor-ivacaftor exposure
(Synonym: Kalydeco (TN))
[3] Elexacaftor,
Ivacaftor (Synonym: Kalydeco),
Tezacaftor
[3] D09916 (Name: Kalydeco (TN)),
D11041 ,
D11507
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
9Elexacaftor/tezacaftor/ivacaftor
(Synonym: Kalydeco (TN))
[3] Elexacaftor,
Ivacaftor (Synonym: Kalydeco),
Tezacaftor
[3] D09916 (Name: Kalydeco (TN)),
D11041 ,
D11507
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
10IVACAFTOR
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
11Ivacaftor (proposed INN)
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
12Ivacaftor 125mg tablet
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
13Ivacaftor 150 mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
14Ivacaftor 150 mg or 250 mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
15Ivacaftor 25 mg/75 mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
16IVACAFTOR 59,5mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
17IVACAFTOR 59.5mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
18Ivacaftor 75 mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
19Ivacaftor 75 mg/150 mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
20IVACAFTOR 75mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
21Ivacaftor Exposed
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
22Ivacaftor or elexacaftor/tezacaftor/ivacaftor
(Synonym: Kalydeco (TN))
[3] Elexacaftor,
Ivacaftor (Synonym: Kalydeco),
Tezacaftor
[3] D09916 (Name: Kalydeco (TN)),
D11041 ,
D11507
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
23Ivacaftor+lumacaftor
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Lumacaftor
[2] D09916 (Name: Kalydeco (TN)),
D10134
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
24Ivacaftor/Ataluren
(Synonym: Kalydeco (TN))
[2] Ataluren,
Ivacaftor (Synonym: Kalydeco)
[2] D09323 ,
D09916 (Name: Kalydeco (TN))
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
25Ivacaftor/Kalydeco[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
26Ivacaftor/Trikafta
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
27Kalydeco[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
28Kalydeco 150 mg film-c[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
29Kalydeco 150 mg film-coated tablets[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
30Kalydeco 150mg[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
31Lumacaftor / ivacaftor
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Lumacaftor
[2] D09916 (Name: Kalydeco (TN)),
D10134
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
32Lumacaftor plus Ivacaftor
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Lumacaftor
[2] D09916 (Name: Kalydeco (TN)),
D10134
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
33Lumacaftor Plus Ivacaftor Combination
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Lumacaftor
[2] D09916 (Name: Kalydeco (TN)),
D10134
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
34Lumacaftor, Ivacaftor Drug Combination
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Lumacaftor
[2] D09916 (Name: Kalydeco (TN)),
D10134
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
35Lumacaftor-ivacaftor
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Lumacaftor
[2] D09916 (Name: Kalydeco (TN)),
D10134
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
36Lumacaftor-Ivacaftor treatment
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Lumacaftor
[2] D09916 (Name: Kalydeco (TN)),
D10134
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
37Lumacaftor/Ivacaftor
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Lumacaftor
[2] D09916 (Name: Kalydeco (TN)),
D10134
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
38Lumacaftor/ivacaftor 100mg/125mg tablets
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Lumacaftor
[2] D09916 (Name: Kalydeco (TN)),
D10134
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
39Lumacaftor/ivacaftor 200mg/125mg
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Lumacaftor
[2] D09916 (Name: Kalydeco (TN)),
D10134
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
40Lumacaftor/ivacaftor 200mg/125mg tablets
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Lumacaftor
[2] D09916 (Name: Kalydeco (TN)),
D10134
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
41Lumacaftor/ivacaftor 200mg/83mg tablet
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Lumacaftor
[2] D09916 (Name: Kalydeco (TN)),
D10134
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
42Orkambi: contains lumacaftor and ivacaftor
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
43Tezacaftor/Ivacaftor
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Tezacaftor
[2] D09916 (Name: Kalydeco (TN)),
D11041
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
44Tezacaftor/Ivacaftor + Ivacaftor
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Tezacaftor
[2] D09916 (Name: Kalydeco (TN)),
D11041
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
45Tezacaftor/Ivacaftor 100mg/150mg
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Tezacaftor
[2] D09916 (Name: Kalydeco (TN)),
D11041
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
46Tezacaftor/Ivacaftor/100mg/150mg
(Synonym: Kalydeco (TN))
[2] Ivacaftor (Synonym: Kalydeco),
Tezacaftor
[2] D09916 (Name: Kalydeco (TN)),
D11041
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
47Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor
(Synonym: Kalydeco (TN))
[4] Elexacaftor,
Ivacaftor (Synonym: Kalydeco),
Lumacaftor,
Tezacaftor
[4] D09916 (Name: Kalydeco (TN)),
D10134 ,
D11041 ,
D11507
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
48VX-659/Tezacaftor/Ivacaftor
(Synonym: Kalydeco (TN))
[3] Ivacaftor (Synonym: Kalydeco),
Tezacaftor,
VX-659
[2] D09916 (Name: Kalydeco (TN)),
D11041
[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
49VX-661 Plus Ivacaftor Combination
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
50VX-661/Ivacaftor
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
51VX-661/ivacaftor (VX-770) 100mg/150 mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
52VX-661/ivacaftor 100 mg/ 150 mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
53VX-661/ivacaftor 100mg/150 mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
54VX-661/ivacaftor 100mg/150mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299
55VX-661/ivacaftor 50 mg/ 75 mg
(Synonym: Kalydeco (TN))
[1] Ivacaftor (Synonym: Kalydeco)[1] D09916 (Name: Kalydeco (TN))[1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299