Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(RS)-baclofen, naltrexone hydrochloride and D-sorbitol[3] Baclofen,
Naltrexone (Apo-naltrexone),
Sorbitol		[3] Sorbitol solution ,
Baclofen ,
Naltrexone (Naltrexone) 💬 		[5] GABBR1,
GABBR2,
OPRD1,
OPRK1,
OPRM1 💬 		[9] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 10 💬
24.5 mg Naltrexone[1] Naltrexone (Apo-naltrexone)[1] Naltrexone (Naltrexone) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 13 💬
3Low dose naltrexone[1] Naltrexone (Apo-naltrexone)[1] Naltrexone (Naltrexone) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 96, 97 💬
4Low-dose naltrexone[1] Naltrexone (Apo-naltrexone)[1] Naltrexone (Naltrexone) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
5NAL----[2] 6, 299 💬
6Nalbuphine[1] Nalbuphine (Nalbuphinum)[1] Nalbuphine (Nalbuphine) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85 💬
7Nalbuphine ER[1] Nalbuphine (Nalbuphinum)[1] Nalbuphine (Nalbuphine) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85 💬
8Nalbuphine Extended-Realease (ER) Tablets[1] Nalbuphine (Nalbuphinum)[1] Nalbuphine (Nalbuphine) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85 💬
9Nalbuphine Extended-Release (ER) Tablets[1] Nalbuphine (Nalbuphinum)[1] Nalbuphine (Nalbuphine) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85 💬
10NALBUPHINE HYDROCHLORIDE[1] Nalbuphine (Nalbuphinum)[1] Nalbuphine (Nalbuphine) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 85 💬
11Nalmefene[1] Nalmefene (Nalmefeno)[1] Nalmefene (Nalmefene) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
12Naloxone[1] Naloxone (Taro-buprenorphine/naloxone)[1] Naloxone (Naloxone, DBL Naloxone) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[2] 6, 226 💬
13NALOXONE HYDROCHLORIDE[1] Naloxone (Taro-buprenorphine/naloxone)[1] Naloxone (Naloxone, DBL Naloxone) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
14NALOXONE HYDROCHLORIDE DIHYDRATE[1] Naloxone (Taro-buprenorphine/naloxone)[1] Naloxone (Naloxone, DBL Naloxone) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
15Naltrexone[1] Naltrexone (Apo-naltrexone)[1] Naltrexone (Naltrexone) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[12] 6, 10, 13, 40, 41, 42, 43, 44, 45, 96, 97, 226 💬
16NALTREXONE CLORIDRATO[1] Naltrexone (Apo-naltrexone)[1] Naltrexone (Naltrexone) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 10 💬
17NALTREXONE HYDROCHLORIDE[1] Naltrexone (Apo-naltrexone)[1] Naltrexone (Naltrexone) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[8] 10, 40, 41, 42, 43, 44, 45, 96 💬
18Naltrexone-HCl[1] Naltrexone (Apo-naltrexone)[1] Naltrexone (Naltrexone) 💬 [3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 96 💬
19Oxycodone naloxone prolonged release tablets[2] Naloxone (Taro-buprenorphine/naloxone),
Oxycodone (Nalocet)		[2] Oxycodone ,
Naloxone (Naloxone, DBL Naloxone) 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
20Oxycodone/naloxone prolonged release t[3] Manganese citrate,
Naloxone (Taro-buprenorphine/naloxone),
Oxycodone (Nalocet)		[2] Oxycodone ,
Naloxone (Naloxone, DBL Naloxone) 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
21Oxycodone/Naloxone Prolonged Release tablets[2] Naloxone (Taro-buprenorphine/naloxone),
Oxycodone (Nalocet)		[2] Oxycodone ,
Naloxone (Naloxone, DBL Naloxone) 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
22Oxycodone/naloxone prolonged release tablets 10 mg /5 mg[3] Manganese citrate,
Naloxone (Taro-buprenorphine/naloxone),
Oxycodone (Nalocet)		[2] Oxycodone ,
Naloxone (Naloxone, DBL Naloxone) 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
23Oxycodone/naloxone prolonged release tablets 10/5 mg[3] Manganese citrate,
Naloxone (Taro-buprenorphine/naloxone),
Oxycodone (Nalocet)		[2] Oxycodone ,
Naloxone (Naloxone, DBL Naloxone) 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
24Oxycodone/naloxone prolonged release tablets 20 mg /10 mg[3] Manganese citrate,
Naloxone (Taro-buprenorphine/naloxone),
Oxycodone (Nalocet)		[2] Oxycodone ,
Naloxone (Naloxone, DBL Naloxone) 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
25Oxycodone/naloxone prolonged release tablets 20/10 mg[3] Manganese citrate,
Naloxone (Taro-buprenorphine/naloxone),
Oxycodone (Nalocet)		[2] Oxycodone ,
Naloxone (Naloxone, DBL Naloxone) 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬
26Oxycodone/naloxone prolonged release tablets 5 mg /2.5 mg[3] Manganese citrate,
Naloxone (Taro-buprenorphine/naloxone),
Oxycodone (Nalocet)		[2] Oxycodone ,
Naloxone (Naloxone, DBL Naloxone) 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
27Oxycodone/naloxone prolonged release tablets 5/2.5 mg[3] Manganese citrate,
Naloxone (Taro-buprenorphine/naloxone),
Oxycodone (Nalocet)		[2] Oxycodone ,
Naloxone (Naloxone, DBL Naloxone) 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[5] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 226 💬