Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1100 mg ELX (VX-445) / 50 mg TEZ / 75 mg IVA FDC----[1] 299 💬
2100 mg ELX /50 mg TEZ /75 mg IVA FDC----[1] 299 💬
3100 mg ELX/50 mg TEZ /75 mg IVA FDC----[1] 299 💬
4100 mg ELX/50 mg TEZ/75 mg IVA fixed dose combination----[1] 299 💬
5100 mg TEZ/150 mg IVA FDC----[1] 299 💬
6100 mg VX-445 /50 mg TEZ/75 mg IVA FDC----[1] 299 💬
7100 mg VX-445/50 mg TEZ /75 mg IVA FDC----[1] 299 💬
8100-mg ELX (VX-445) / 50-mg TEZ / 75-mg IVA FDC----[1] 299 💬
9100-mg ELX (VX-455) / 50-mg TEZ / 75-mg IVA FDC----[1] 299 💬
10100-mg ELX / 50-mg TEZ / 75 -mg IVA FDC----[1] 299 💬
11100-mg VX-445 / 50-mg TEZ / 75- mg IVA FDC----[1] 299 💬
12100-mg VX-445 / 50-mg TEZ / 75-mg IVA FDC----[1] 299 💬
13100-mg VX-445 /50-mg TEZ/75-mg----[1] 299 💬
14100-mg VX-445/50-mg TEZ/75-mg IVA FDC----[1] 299 💬
15100g ELX / 50mg TEZ / 75mg IVA----[1] 299 💬
16100mg ELX/50mg TEZ /75mg IVA----[1] 299 💬
17100mg VX-445/50mg TEZ /75mg IVA FDC----[1] 299 💬
1850 mg ELX/25 mg TEZ/37.5 mg IVA----[1] 299 💬
1950 mg ELX/25 mg TEZ/37.5 mg IVA fixed dose combination----[1] 299 💬
2080mg ELX / 40mg TEZ / 60mg IVA----[1] 299 💬
21Elexacaftor / Ivacaftor / Tezacaftor[3] Elexacaftor,
Ivacaftor,
Tezacaftor (Tezacaftor)		[3] Ivacaftor ,
Tezacaftor (Tezacaftor),
Elexacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
22Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening[3] Elexacaftor,
Ivacaftor,
Tezacaftor (Tezacaftor)		[3] Ivacaftor ,
Tezacaftor (Tezacaftor),
Elexacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
23Elexacaftor-tezacaftor-ivacaftor exposure[3] Elexacaftor,
Ivacaftor,
Tezacaftor (Tezacaftor)		[3] Ivacaftor ,
Tezacaftor (Tezacaftor),
Elexacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
24Elexacaftor/tezacaftor/ivacaftor[3] Elexacaftor,
Ivacaftor,
Tezacaftor (Tezacaftor)		[3] Ivacaftor ,
Tezacaftor (Tezacaftor),
Elexacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
25ELX (VX-445)/TEZ (VX-661)/IVA (VX-770)----[1] 299 💬
26ELX/TEZ/IVA----[1] 299 💬
27Ivacaftor or elexacaftor/tezacaftor/ivacaftor[3] Elexacaftor,
Ivacaftor,
Tezacaftor (Tezacaftor)		[3] Ivacaftor ,
Tezacaftor (Tezacaftor),
Elexacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
28TEZ----[1] 299 💬
29TEZ/IVA----[1] 299 💬
30TEZACAFTOR[1] Tezacaftor (Tezacaftor)[1] Tezacaftor (Tezacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
31Tezacaftor (TEZ)[1] Tezacaftor (Tezacaftor)[1] Tezacaftor (Tezacaftor) 💬 [1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
32Tezacaftor/Ivacaftor[2] Ivacaftor,
Tezacaftor (Tezacaftor)		[2] Ivacaftor ,
Tezacaftor (Tezacaftor) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
33Tezacaftor/Ivacaftor + Ivacaftor[2] Ivacaftor,
Tezacaftor (Tezacaftor)		[2] Ivacaftor ,
Tezacaftor (Tezacaftor) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
34Tezacaftor/Ivacaftor 100mg/150mg[2] Ivacaftor,
Tezacaftor (Tezacaftor)		[2] Ivacaftor ,
Tezacaftor (Tezacaftor) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
35Tezacaftor/Ivacaftor/100mg/150mg[2] Ivacaftor,
Tezacaftor (Tezacaftor)		[2] Ivacaftor ,
Tezacaftor (Tezacaftor) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
36Tezepelumab[1] Tezepelumab (Tezepelumab)[1] Tezepelumab (Tezepelumab, Tezepelumab, Tezepelumab-ekko, Tezspire) 💬 [1] TSLP 💬 [2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 98 💬
37Tezepelumab via APFS[1] Tezepelumab (Tezepelumab)[1] Tezepelumab (Tezepelumab, Tezepelumab, Tezepelumab-ekko, Tezspire) 💬 [1] TSLP 💬 [2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[1] 98 💬
38Tezosentan[1] Tezosentan (Tezosentan)---[1] 86 💬
39Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor[4] Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor (Tezacaftor)		[4] Ivacaftor ,
Lumacaftor ,
Tezacaftor (Tezacaftor),
Elexacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
40VX-121/TEZ/D-IVA----[1] 299 💬
41VX-121/tezacaftor/deutivacaftor[2] Deutivacaftor,
Tezacaftor (Tezacaftor)		[2] Tezacaftor (Tezacaftor),
Deutivacaftor 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
42VX-445 / TEZ / IVA----[1] 299 💬
43VX-445 / TEZ / IVA FDC----[1] 299 💬
44VX-445 /TEZ/IVA----[1] 299 💬
45VX-445/TEZ/IVA----[1] 299 💬
46VX-659/ TEZ/IVA[1] VX-659---[1] 299 💬
47VX-659/TEZ/IVA[1] VX-659---[1] 299 💬
48VX-659/Tezacaftor/Ivacaftor[3] Ivacaftor,
Tezacaftor (Tezacaftor),
VX-659		[2] Ivacaftor ,
Tezacaftor (Tezacaftor) 💬 		[1] CFTR 💬 [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
49VX-661/VX-770 (TEZ/IVA)----[1] 299 💬