Target Gene/Pathway Pathway / Gene

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No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Acute myeloid leukemia 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96 ...
2	Acute myeloid leukemia 💬	[2] PML, RARA 💬	D00094 💬	Tretinoin	[6] 2 , 62, 63, 75, 94, 231 💬
3	Adipocytokine signaling pathway 💬	[1] MTOR 💬	D00753 💬	Sirolimus	[40] 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96 ...
4	Alcoholic liver disease 💬	[1] C3 💬	D11613 💬	Pegcetacoplan	[4] 2 , 61, 62, 222 💬
5	Alcoholic liver disease 💬	[1] C5 💬	D11696 💬	Crovalimab	[2] 62, 109 💬
6	Alcoholic liver disease 💬	[1] C5 💬	D03940 💬	Eculizumab	[7] 11, 13, 14, 61, 62, 109, 222 💬
7	Alcoholic liver disease 💬	[1] C5 💬	D11473 💬	Nomacopan	[3] 62, 109, 162 💬
8	Alcoholic liver disease 💬	[1] C5 💬	D11477 💬	Pozelimab	[2] 11, 62 💬
9	Alcoholic liver disease 💬	[1] C5 💬	D11054 💬	Ravulizumab	[7] 2 , 11, 13, 50, 62, 66, 109 💬
10	Alcoholic liver disease 💬	[1] C5 💬	D12357 💬	Zilucoplan	[3] 2 , 11, 62 💬

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