13. Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

Clinical trials : 3,340 / Drugs : 2,163 - (DrugBank : 383) / Drug target genes : 241 - Drug target pathways : 238

26 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2019-004980-36-RO (EUCTR)	29/06/2021	27/04/2022	Evobrutinib compared to Teriflunomide in participants with Relapsing Multiple Sclerosis	A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled ...	Relapsing Multiple Sclerosis MedDRA version: 20.0;Level: PT;Classification code 10048393;Term: Multi ...	Product Name: Evobrutinib Product Code: M2951 INN or Proposed INN: EVOBRUTINIB Other descriptive name: ...	Merck Healthcare KGaA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	930	Phase 3	Portugal;Belarus;United States;Philippines;Saudi Arabia;Slovakia;Greece;Spain;Thailand;Ukraine;Russi ...
2	EUCTR2019-004980-36-SI (EUCTR)	18/03/2021	06/10/2020	Evobrutinib compared to Teriflunomide in participants with Relapsing Multiple Sclerosis	A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled ...	Relapsing Multiple Sclerosis MedDRA version: 20.0;Level: PT;Classification code 10048393;Term: Multi ...	Product Name: Evobrutinib Product Code: M2951 INN or Proposed INN: EVOBRUTINIB Other descriptive name: ...	Merck Healthcare KGaA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	930	Phase 3	Portugal;Belarus;United States;Philippines;Saudi Arabia;Slovakia;Greece;Spain;Thailand;Ukraine;Russi ...
3	EUCTR2019-004980-36-NO (EUCTR)	16/12/2020	03/07/2020	Evobrutinib compared to Teriflunomide in participants with Relapsing Multiple Sclerosis	A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled ...	Relapsing Multiple Sclerosis MedDRA version: 20.0;Level: PT;Classification code 10048393;Term: Multi ...	Product Name: Evobrutinib Product Code: M2951 INN or Proposed INN: EVOBRUTINIB Other descriptive name: ...	Merck Healthcare KGaA	NULL	Not Recruiting			Female: yes Male: yes	930	Phase 3	Portugal;Belarus;United States;Philippines;Saudi Arabia;Slovakia;Greece;Spain;Thailand;Ukraine;Russi ...
4	EUCTR2019-004972-20-FI (EUCTR)	06/11/2020	04/09/2020	Evobrutinib compared to Teriflunomide in participants with Relapsing Multiple Sclerosis	A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled ...	Relapsing Multiple Sclerosis MedDRA version: 20.0;Level: PT;Classification code 10048393;Term: Multi ...	Product Name: Evobrutinib Product Code: M2951 INN or Proposed INN: EVOBRUTINIB Other descriptive name: ...	Merck Healthcare KGaA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	930	Phase 3	Serbia;United States;Hong Kong;Taiwan;Estonia;Spain;Ukraine;Israel;Chile;Russian Federation;Colombia ...
5	EUCTR2019-004972-20-DE (EUCTR)	05/11/2020	11/05/2020	Evobrutinib compared to Teriflunomide in participants with Relapsing Multiple Sclerosis	A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled ...	Relapsing Multiple Sclerosis MedDRA version: 20.0;Level: PT;Classification code 10048393;Term: Multi ...	Product Name: Evobrutinib Product Code: M2951 INN or Proposed INN: EVOBRUTINIB Other descriptive name: ...	Merck Healthcare KGaA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	930	Phase 3	Serbia;United States;Taiwan;Hong Kong;Estonia;Spain;Ukraine;Russian Federation;Israel;Chile;Colombia ...
6	EUCTR2019-004980-36-LT (EUCTR)	22/10/2020	25/05/2020	Evobrutinib compared to Teriflunomide in participants with Relapsing Multiple Sclerosis	A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled ...	Relapsing Multiple Sclerosis MedDRA version: 20.0;Level: PT;Classification code 10048393;Term: Multi ...	Product Name: Evobrutinib Product Code: M2951 INN or Proposed INN: EVOBRUTINIB Other descriptive name: ...	Merck Healthcare KGaA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	930	Phase 3	Portugal;Belarus;United States;Philippines;Saudi Arabia;Slovakia;Greece;Spain;Thailand;Ukraine;Russi ...
7	EUCTR2019-004980-36-BG (EUCTR)	12/10/2020	19/06/2020	Evobrutinib compared to Teriflunomide in participants with Relapsing Multiple Sclerosis	A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled ...	Relapsing Multiple Sclerosis MedDRA version: 20.0;Level: PT;Classification code 10048393;Term: Multi ...	Product Name: Evobrutinib Product Code: M2951 INN or Proposed INN: EVOBRUTINIB Other descriptive name: ...	Merck Healthcare KGaA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	930	Phase 3	Portugal;Belarus;United States;Philippines;Saudi Arabia;Slovakia;Greece;Spain;Thailand;Ukraine;Russi ...
8	EUCTR2019-004972-20-CZ (EUCTR)	01/10/2020	05/06/2020	Evobrutinib compared to Teriflunomide in participants with Relapsing Multiple Sclerosis	A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled ...	Relapsing Multiple Sclerosis MedDRA version: 20.0;Level: PT;Classification code 10048393;Term: Multi ...	Product Name: Evobrutinib Product Code: M2951 INN or Proposed INN: EVOBRUTINIB Other descriptive name: ...	Merck Healthcare KGaA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	930	Phase 3	Serbia;United States;Hong Kong;Taiwan;Estonia;Spain;Ukraine;Israel;Chile;Russian Federation;Colombia ...
9	EUCTR2019-004980-36-DE (EUCTR)	29/09/2020	08/09/2020	Evobrutinib compared to Teriflunomide in participants with Relapsing Multiple Sclerosis	A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled ...	Relapsing Multiple Sclerosis MedDRA version: 20.0;Level: PT;Classification code 10048393;Term: Multi ...	Product Name: Evobrutinib Product Code: M2951 INN or Proposed INN: EVOBRUTINIB Other descriptive name: ...	Merck Healthcare KGaA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	930	Phase 3	Germany;Puerto Rico;Russian Federation;Singapore;United States;Malaysia;Thailand;Portugal;Saudi Arab ...
10	EUCTR2019-004972-20-BG (EUCTR)	23/09/2020	19/06/2020	Evobrutinib compared to Teriflunomide in participants with Relapsing Multiple Sclerosis	A Phase III, Multicenter, Randomized, Parallel Group, Double Blind, Double Dummy, Active Controlled ...	Relapsing Multiple Sclerosis MedDRA version: 20.0;Level: PT;Classification code 10048393;Term: Multi ...	Product Name: Evobrutinib Product Code: M2951 INN or Proposed INN: EVOBRUTINIB Other descriptive name: ...	Merck Healthcare KGaA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	930	Phase 3	Serbia;United States;Hong Kong;Taiwan;Estonia;Spain;Ukraine;Israel;Chile;Russian Federation;Colombia ...

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