13. Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

Clinical trials : 3,340 / Drugs : 2,163 - (DrugBank : 383) / Drug target genes : 241 - Drug target pathways : 238

57 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2012-000541-12-HR (EUCTR)	23/04/2019	17/05/2019	Clinical study to compare the efficacy and safety of ponesimodto placebo in subjects with active rel ...	Multicenter, randomized, double-blind, parallel-group, add-on, superiority study to compare the effi ...	Relapsing multiple sclerosis MedDRA version: 20.1;Level: PT;Classification code 10028245;Term: Multi ...	Product Name: Ponesimod Product Code: ACT-128800 INN or Proposed INN: Ponesimod Other descriptive name: ...	Actelion Pharmaceuticals Ltd.	NULL	Not Recruiting			Female: yes Male: yes	600	Phase 3	United States;Portugal;Greece;Finland;Spain;Austria;Russian Federation;United Kingdom;Switzerland;It ...
2	NCT05762003 (ClinicalTrials.gov)	January 1, 2019	9/2/2023	Czech Pharmaco-epidemiological Study on Disease Modifying Drugs	Czech Pharmaco-epidemiological Real World Data Study Focused on Effectiveness of Different Disease M ...	Multiple Sclerosis	Drug: interferons, glatiramer acetate, teriflunomide, dimethyl fumarate, alemtuzumab, cladribine, fi ...	IMPULS Endowment Fund	NULL	Completed	N/A	N/A	All	17478		Czechia
3	EUCTR2016-004719-10-GR (EUCTR)	15/10/2018	24/07/2018	Multicenter, non-comparative extension to study AC-058B301, to investigate the long-term safety, tol ...	Multicenter, non-comparative extension to study AC-058B301, to investigate the long-term safety, tol ...	Relapsing multiple sclerosis. MedDRA version: 21.1;Level: PT;Classification code 10063400;Term: Seco ...	Product Name: Ponesimod Product Code: ACT-128800 INN or Proposed INN: PONESIMOD Product Name: Ponesimod ...	Actelion Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	800	Phase 3	United States;Belarus;Serbia;Portugal;Greece;Spain;Ukraine;Israel;Russian Federation;Italy;France;La ...
4	EUCTR2016-004719-10-FI (EUCTR)	25/07/2018	12/06/2018	A research study to look at the long term benefits and risks of ponesimod20 mg treatment for patient ...	Multicenter, non-comparative extension to study AC-058B301, to investigate the long-term safety, tol ...	Relapsing multiple sclerosis. MedDRA version: 21.1;Level: PT;Classification code 10063400;Term: Seco ...	Product Name: Ponesimod Product Code: ACT-128800 INN or Proposed INN: PONESIMOD Product Name: Ponesimod ...	Actelion Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	800	Phase 3	United States;Serbia;Belarus;Portugal;Greece;Spain;Ukraine;Russian Federation;Israel;Italy;France;La ...
5	EUCTR2016-004719-10-PT (EUCTR)	02/07/2018	12/02/2018	A research study to look at the long term benefits and risks of ponesimod20 mg treatment for patient ...	Multicenter, non-comparative extension to study AC-058B301, to investigate the long-term safety, tol ...	relapsing multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063400;Term: Secon ...	Product Name: Ponesimod Product Code: ACT-128800 INN or Proposed INN: PONESIMOD Product Name: Ponesimod ...	Actelion Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	800	Phase 3	United States;Serbia;Belarus;Portugal;Greece;Spain;Ukraine;Russian Federation;Israel;Italy;France;La ...
6	EUCTR2012-000541-12-BE (EUCTR)	07/05/2018	09/02/2018	Clinical study to compare the efficacy and safety of ponesimodto placebo in subjects with active rel ...	Multicenter, randomized, double-blind, parallel-group, add-on, superiority study to compare the effi ...	Relapsing multiple sclerosis MedDRA version: 20.1;Level: PT;Classification code 10028245;Term: Multi ...	Product Name: Ponesimod Product Code: ACT-128800 INN or Proposed INN: Ponesimod Other descriptive name: ...	Actelion Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	600	Phase 3	Portugal;United States;Greece;Finland;Spain;Austria;Israel;Italy;France;Czech Republic;Hungary;Canad ...
7	EUCTR2016-004719-10-GB (EUCTR)	26/04/2018	22/05/2018	A research study to look at the long term benefits and risks of ponesimod20 mg treatment for patient ...	Multicenter, non-comparative extension to study AC-058B301, to investigate the long-term safety, tol ...	relapsing multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063400;Term: Secon ...	Product Name: Ponesimod Product Code: ACT-128800 INN or Proposed INN: PONESIMOD Product Name: Ponesimod ...	Actelion Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	800	Phase 3	United States;Belarus;Portugal;Serbia;Greece;Spain;Ukraine;Israel;Russian Federation;Italy;France;La ...
8	EUCTR2016-004719-10-HR (EUCTR)	27/03/2018	12/04/2018	A research study to look at the long term benefits and risks of ponesimod20 mg treatment for patient ...	Multicenter, non-comparative extension to study AC-058B301, to investigate the long-term safety, tol ...	relapsing multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063400;Term: Secon ...	Product Name: Ponesimod Product Code: ACT-128800 INN or Proposed INN: PONESIMOD Product Name: Ponesimod ...	Actelion Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	800	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	Serbia;Belarus;United States;Portugal;Greece;Spain;Ukraine;Russian Federation;Israel;Italy;France;La ...
9	EUCTR2016-004719-10-LV (EUCTR)	30/01/2018	10/11/2017	A research study to look at the long term benefits and risks of ponesimod20 mg treatment for patient ...	Multicenter, non-comparative extension to study AC-058B301, to investigate the long-term safety, tol ...	relapsing multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063400;Term: Secon ...	Product Name: Ponesimod Product Code: ACT-128800 INN or Proposed INN: PONESIMOD Product Name: Ponesimod ...	Actelion Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	800	Phase 3	Russian Federation;United States;Portugal;Greece;Latvia;Sweden;Poland;Bulgaria;France;Lithuania;Serb ...
10	EUCTR2016-004719-10-BG (EUCTR)	24/01/2018	01/11/2017	A research study to look at the long term benefits and risks of ponesimod20 mg treatment for patient ...	Multicenter, non-comparative extension to study AC-058B301, to investigate the long-term safety, tol ...	relapsing multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063400;Term: Secon ...	Product Name: Ponesimod Product Code: ACT-128800 INN or Proposed INN: PONESIMOD Product Name: Ponesimod ...	Actelion Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	800	Phase 3	United States;Portugal;Belarus;Serbia;Greece;Spain;Ukraine;Israel;Russian Federation;Italy;France;La ...

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