218. Alport syndrome Clinical trials / Disease details

Clinical trials : 30 / Drugs : 36 - (DrugBank : 15) / Drug target genes : 8 - Drug target pathways : 46

3 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05133050 (ClinicalTrials.gov)	January 1, 2022	27/10/2021	Safety and Efficacy of ACEI in Alport Syndrome Patients With COL4A3/COL4A4/COL4A5 Variants	Safety and Efficacy of Early Angiotensin-converting Enzyme Inhibition in Patients With Alport Syndrome Carrying Pathogenic Heterozygous COL4A3,COL4A4 or COL4A5 Mutations	Alport Syndrome	Drug: Ramipril	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine	NULL	Not yet recruiting	30 Years	50 Years	All	510	N/A	China
2	NCT01485978 (ClinicalTrials.gov)	March 2012	2/12/2011	Efficacy and Safety Study to Delay Renal Failure in Children With Alport Syndrome	Early Prospective Therapy Trial to Delay Renal Failure in Children With Alport Syndrome	Renal Insufficiency, Chronic	Drug: Ramipril;Drug: placebo to ramipril	Institut fuer anwendungsorientierte Forschung und klinische Studien GmbH	University Medical Center Goettingen;German Federal Ministry of Education and Research	Completed	24 Months	18 Years	All	66	Phase 3	Germany
3	EUCTR2010-024300-10-DE (EUCTR)	27/02/2012	12/12/2011	Early prospective therapy trial to delay renal failure in children with Alport syndrome. - EARLY PRO-TECT Alport	Early prospective therapy trial to delay renal failure in children with Alport syndrome. - EARLY PRO-TECT Alport	Alport's syndrome MedDRA version: 19.1;Level: PT;Classification code 10001843;Term: Alport's syndrome;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]	Trade Name: Delix Product Name: Delix Other descriptive name: RAMIPRIL	University Medical Center Göttingen	NULL	Not Recruiting			Female: yes Male: yes	120	Phase 3	Germany