224. Purpura nephritis Clinical trials / Disease details
Clinical trials : 16 / Drugs : 43 - (DrugBank : 21) / Drug target genes : 15 - Drug target pathways : 58
Showing 1 to 10 of 16 diseases
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ChiCTR2200057905 | 2022-04-01 | 2022-03-21 | A prospective, open, randomized controlled study of hydroxychloroquine sulfate in the treatment of adult Henoch Schonlein purpura nephritis A prospective, open, randomized controlled study of hydroxychloroquine sulfate in the treatment of a ... | A prospective, open, randomized controlled study of hydroxychloroquine sulfate in the treatment of adult Henoch Schonlein purpura nephritis A prospective, open, randomized controlled study of hydroxychloroquine sulfate in the treatment of a ... | Henoch Schonlein purpura nephritis | Experimental group:Hydroxychloroquine sulfate;Control group:Conventional therapy; | Daping Hospital, Army Medical University | NULL | Recruiting | 18 | Both | Experimental group:42;Control group:42; | Phase 4 | China | |
| 2 | ChiCTR2000040625 | 2021-01-01 | 2020-12-04 | Therapeutic effect of hydroxychloroquine on children Henoch-Schonlein purpura nephritis | Therapeutic effect of hydroxychloroquine on children Henoch-Schonlein purpura nephritis | Henoch-Schonlein purpura nephritis | A:Basic treatment + hydroxychloroquine (5mg/kg.d, taken orally in 2 doses);B:Basic treatment; | Shengjing Hospital of China Medical University | NULL | Pending | 3 | 14 | Both | A:20;B:20; | N/A | China |
| 3 | ChiCTR2000039686 | 2020-12-01 | 2020-11-05 | To evaluate the efficacy and safety of tacrolimus in the treatment of children with Henoch Schonlein purpura nephritis To evaluate the efficacy and safety of tacrolimus in the treatment of children with Henoch Schonlein ... | A multicentre, randomized, prospective, observational study evaluating the efficacy and safety of tacrolimus in the treatment of Henoch Schonlein purpura nephritis in children at 24 weeks A multicentre, randomized, prospective, observational study evaluating the efficacy and safety of ta ... | Henoch Schonlein purpura nephritis | Experimental drug treatment group:Tacroximus capsule (trade name: Saifu X R), 0.1mg /kg/d, orally taken 1 hour before or 2-3 hours after meals twice a day for 24 weeks;Prednisone 1.5-2mg/kg/d was taken orally for 4 weeks and then changed to oral administration every other day for 4 weeks, gradually reducing the amount.;Control treatment group:Cyclophosphamide 8-10mg/ kg/d was given intravenously for 2 consecutive days, once every 2-4 weeks for 4 consecutive times, and once every 3 weeks for 2 consecutive times for 6 times in total.Prednisone 1.5-2mg/kg/d was taken orally with breakfast in the morning. ; Experimental drug treatment group:Tacroximus capsule (trade name: Saifu X R), 0.1mg /kg/d, orally ta ... | Shengjing Hospital of China Medical University | NULL | Recruiting | Both | Experimental drug treatment group:156;Control treatment group:78; | Phase 4 | China | ||
| 4 | ChiCTR2000039700 | 2020-11-06 | 2020-11-06 | A single center randomized controlled clinical study on the treatment of Children with Purpura nephritis with Huai-Qi-Huang Granules A single center randomized controlled clinical study on the treatment of Children with Purpura nephr ... | A single center randomized controlled clinical study on the treatment of Children with Purpura nephritis with Huai-Qi-Huang Granules A single center randomized controlled clinical study on the treatment of Children with Purpura nephr ... | Children with purpura nephritis | experimental group:Huaiqihuang;control group:valsartan; | Children's Hospital, Zhejiang University School of Medicine | NULL | Recruiting | 6 | 14 | Male | experimental group:5;control group:5; | China | |
| 5 | ITMCTR2100004424 | 2020-11-06 | 2020-11-06 | A single center randomized controlled clinical study on the treatment of Children with Purpura nephritis with Huai-Qi-Huang Granules A single center randomized controlled clinical study on the treatment of Children with Purpura nephr ... | A single center randomized controlled clinical study on the treatment of Children with Purpura nephritis with Huai-Qi-Huang Granules A single center randomized controlled clinical study on the treatment of Children with Purpura nephr ... | Children with purpura nephritis | experimental group:Huaiqihuang;control group:valsartan; | Children's Hospital, Zhejiang University School of Medicine | NULL | Recruiting | 6 | 14 | Male | experimental group:5;control group:5; | China | |
| 6 | NCT04623866 (ClinicalTrials.gov) | November 1, 2020 | 25/10/2020 | Study on the Treatment of Children With Purpura Nephritis With Huaiqihuang Granules | A Single Center Randomized Controlled Clinical Study on the Treatment of Children With Purpura Nephritis With Huaiqihuang Granules A Single Center Randomized Controlled Clinical Study on the Treatment of Children With Purpura Nephr ... | Henoch Schönlein Purpura Nephritis | Drug: Huaiqinhuang;Drug: valsartan | The Children's Hospital of Zhejiang University School of Medicine | NULL | Not yet recruiting | 6 Years | 14 Years | All | 10 | Early Phase 1 | China |
| 7 | ChiCTR2000037540 | 2020-09-30 | 2020-08-28 | Effects and safety of MMF combined with short course steriods therapy in children Henoch-Schnlein purpura nephritis Effects and safety of MMF combined with short course steriods therapy in children Henoch-Schnlein pu ... | Effects and safety of MMF combined with short course steriods therapy in children Henoch-Schnlein purpura nephritis Effects and safety of MMF combined with short course steriods therapy in children Henoch-Schnlein pu ... | children Henoch-Schnlein purpura nephritis | experimental group:mycophenolate mofetil;control group:traditional course steriod; | Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine | NULL | Pending | 2 | 14 | Both | experimental group:30;control group:30; | N/A | China |
| 8 | ChiCTR1800017046 | 2018-07-15 | 2018-07-10 | The research of Gd - IgA1 with purpura nephritis | The research of Gd - IgA1 with purpura nephritis | Henoch-Schnlein purpura nephritis;D69.005+ | Gold Standard:Allergic purpura diagnostic criteria: 1) the tangibility purpura; 2) the onset age < 20 years old; 3) with acute abdominal pain; 4) biopsy showed small veins and arteries around a neutrophil infiltration. In the above four standard, conform to article 2 or above can be diagnosed as allergic purpura. Purpur;Index test:Gd-IgA1, IgA, IgG, C3; GoldStandard:Allergic purpura diagnostic criteria: 1) the tangibility purpura; 2) the onset age < 20 ... | College of Pediatrics, University of South China/Children's Hospital of Hu'nan Province | NULL | Recruiting | 1 | 14 | Both | Target condition:250;Difficult condition:24 | China | |
| 9 | NCT02878018 (ClinicalTrials.gov) | September 2016 | 17/8/2016 | Cohort Study on Traditional Chinese Medicine Diagnosis and Treatment of Children With Henoch-Schonlein Purpura Nephritis Cohort Study on Traditional Chinese Medicine Diagnosis and Treatment of Children With Henoch-Schonle ... | Cohort Study on Traditional Chinese Medicine Diagnosis and Treatment of Children With Henoch-Schonlein Purpura Nephritis Cohort Study on Traditional Chinese Medicine Diagnosis and Treatment of Children With Henoch-Schonle ... | Henoch-Schonlein Purpura Nephritis | Drug: Qi-Ji Shen-Kang formula; Zhu-Bai formula; Yu-Shen formula;Drug: angiotensin-converting enzyme (ACE) inhibitor; adrenergic receptor binder (ARB); adrenal cortical hormone; Tripterygium wilfordii polyglycosidium; immunosuppressant Drug: Qi-Ji Shen-Kang formula; Zhu-Bai formula; Yu-Shen formula;Drug: angiotensin-converting enzyme ... | Liaoning University of Traditional Chinese Medicine | First Hospital of China Medical University;Shengjing Hospital | Active, not recruiting | 5 Years | 18 Years | All | 600 | China | |
| 10 | ChiCTR2200055323 | 2016-08-01 | 2022-01-07 | Efficacy and safety of tacrolimus in the treatment of children with allergic purpura nephritis | Efficacy and safety of tacrolimus in the treatment of children with allergic purpura nephritis | Allergic purpuric nephritis in children | Tacrolimus group:Tacrolimus;Cyclophosphamide group:Cyclophosphamide;Mycophenolate mofetil group:Mycophenolate mofetil; Tacrolimusgroup:Tacrolimus;Cyclophosphamidegroup:Cyclophosphamide;Mycophenolatemofetilgroup:Mycophen ... | Lanzhou University Second Hospital | NULL | Completed | 4 | 18 | Both | Tacrolimus group:31;Cyclophosphamide group:31;Mycophenolate mofetil group:30; | Phase 4 | China |