226. Interstitial cystitis with Hunners ulcer Clinical trials / Disease details

Clinical trials : 145 / Drugs : 156 - (DrugBank : 51) / Drug target genes : 64 - Drug target pathways : 146

6 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05275647 (ClinicalTrials.gov)	May 18, 2021	13/1/2022	Efficacy and Safety of Low Energy Shock Wave Plus BotulinumToxin A in Treating Patients With Interstitial Cystitis	Therapeutic Efficacy and Safety of Low Energy Shock Wave (LESW) Plus Botulinum Toxin A Instillation in Treatment of Patients With Interstitial Cystitis Refractory to Conventional Therapy - A Clinical and Immunohistochemistry Study	Interstitial Cystitis	Drug: BOTOX 100U in normal saline;Drug: Normal saline	Buddhist Tzu Chi General Hospital	Ministry of Science and Technology, Taiwan;Hualien Tzu Chi General Hospital	Recruiting	20 Years	N/A	All	75	Phase 2	Taiwan
2	NCT03076762 (ClinicalTrials.gov)	March 2015	1/3/2017	Comparative Study Suburothelial and Trigonal Botulinum Toxin A Injection in Treatment of Interstitial Cystitis	Comparative Study of the Efficacy and Safety Between Suburothelial and Trigonal Intravesical Botulinum Toxin A Injection in Treatment of Interstitial Cystitis Refractory to Conventional Treatment - A Prospective, Randomized, Clinical Trial	Bladder Pain Syndrome	Drug: intravesical onabotulinumtoxinA injection	Buddhist Tzu Chi General Hospital	NULL	Recruiting	18 Years	N/A	All	60	Phase 2	Taiwan
3	NCT02247557 (ClinicalTrials.gov)	September 2014	15/9/2014	Intravesical Instillation of Liposome Encapsulated Botulinum Toxin A (Lipotoxin) in Treatment of Interstitial Cystitis	Intravesical Instillation of Liposome Encapsulated Botulinum Toxin A (Lipotoxin) in Treatment of Interstitial Cystitis — a Randomized, Double-blind, Placebo-controlled, Prospective Study	Interstitial Cystitis	Drug: Liposome encapsulated BoNT-A;Drug: BOTOX 200U in normal saline;Drug: Normal saline	Buddhist Tzu Chi General Hospital	NULL	Completed	20 Years	80 Years	All	90	Phase 2	Taiwan
4	NCT01969773 (ClinicalTrials.gov)	December 2012	22/10/2013	Intravesical Botulinum Toxin A Injections in Treatment of Interstitial Cystitis Refractory to Conventional Treatment	Intravesical Botulinum Toxin A Injection in Treatment of Interstitial Cystitis Refractory to Conventional Treatment - A Prospective, Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial	Interstitial Cystitis	Drug: Botulinum toxin A;Drug: Normal saline instillation	Buddhist Tzu Chi General Hospital	NULL	Completed	20 Years	85 Years	All	60	Phase 2	Taiwan
5	EUCTR2007-005164-27-NL (EUCTR)	22/02/2008	17/10/2007	Botulinum toxin A intravesical injections in the treatment of Bladder Pain Syndrome/Interstitial Cystitis	Botulinum toxin A intravesical injections in the treatment of Bladder Pain Syndrome/Interstitial Cystitis	Interstitial Cystitis (IC) is a syndrome characterized by bladder pain associated with urgency, frequency, nocturia, dysuria and sterile urine. The patho-physiology remains largely unclear. No universally, effective, treatment exists. Botulinum toxin-A (BTX-A) inhibits the release of acetylcholine at the presynaptic cholinergic junction resulting in temporally muscle relaxation and bladder desensitisation. We explore the effects of intravesical injections with BTX-A in the treatment of IC.	Trade Name: Botox	research office urology VUmc	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	12		Netherlands
6	NCT00194610 (ClinicalTrials.gov)	May 2004	13/9/2005	Botox as a Treatment for Interstitial Cystitis in Women	Botox (Botulinum Toxin A) as a Treatment for Interstitial Cystitis in Women: A Randomized Placebo Controlled Trial	Painful Bladder Syndrome;Interstitial Cystitis	Drug: Botox;Other: normal saline	University of Washington	Paul G. Allen Family Foundation	Completed	18 Years	N/A	Female	20	Phase 4	United States