226. Interstitial cystitis with Hunners ulcer Clinical trials / Disease details


Clinical trials : 145 Drugs : 156 - (DrugBank : 51) / Drug target genes : 64 - Drug target pathways : 146

  
6 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT05275647
(ClinicalTrials.gov)
May 18, 202113/1/2022Efficacy and Safety of Low Energy Shock Wave Plus BotulinumToxin A in Treating Patients With Interstitial CystitisTherapeutic Efficacy and Safety of Low Energy Shock Wave (LESW) Plus Botulinum Toxin A Instillation in Treatment of Patients With Interstitial Cystitis Refractory to Conventional Therapy - A Clinical and Immunohistochemistry StudyInterstitial CystitisDrug: BOTOX 100U in normal saline;Drug: Normal salineBuddhist Tzu Chi General HospitalMinistry of Science and Technology, Taiwan;Hualien Tzu Chi General HospitalRecruiting20 YearsN/AAll75Phase 2Taiwan
2NCT03076762
(ClinicalTrials.gov)
March 20151/3/2017Comparative Study Suburothelial and Trigonal Botulinum Toxin A Injection in Treatment of Interstitial CystitisComparative Study of the Efficacy and Safety Between Suburothelial and Trigonal Intravesical Botulinum Toxin A Injection in Treatment of Interstitial Cystitis Refractory to Conventional Treatment - A Prospective, Randomized, Clinical TrialBladder Pain SyndromeDrug: intravesical onabotulinumtoxinA injectionBuddhist Tzu Chi General HospitalNULLRecruiting18 YearsN/AAll60Phase 2Taiwan
3NCT02247557
(ClinicalTrials.gov)
September 201415/9/2014Intravesical Instillation of Liposome Encapsulated Botulinum Toxin A (Lipotoxin) in Treatment of Interstitial CystitisIntravesical Instillation of Liposome Encapsulated Botulinum Toxin A (Lipotoxin) in Treatment of Interstitial Cystitis — a Randomized, Double-blind, Placebo-controlled, Prospective StudyInterstitial CystitisDrug: Liposome encapsulated BoNT-A;Drug: BOTOX 200U in normal saline;Drug: Normal salineBuddhist Tzu Chi General HospitalNULLCompleted20 Years80 YearsAll90Phase 2Taiwan
4NCT01969773
(ClinicalTrials.gov)
December 201222/10/2013Intravesical Botulinum Toxin A Injections in Treatment of Interstitial Cystitis Refractory to Conventional TreatmentIntravesical Botulinum Toxin A Injection in Treatment of Interstitial Cystitis Refractory to Conventional Treatment - A Prospective, Multicenter, Randomized, Double-blind, Placebo-controlled Clinical TrialInterstitial CystitisDrug: Botulinum toxin A;Drug: Normal saline instillationBuddhist Tzu Chi General HospitalNULLCompleted20 Years85 YearsAll60Phase 2Taiwan
5EUCTR2007-005164-27-NL
(EUCTR)
22/02/200817/10/2007Botulinum toxin A intravesical injections in the treatment of Bladder Pain Syndrome/Interstitial CystitisBotulinum toxin A intravesical injections in the treatment of Bladder Pain Syndrome/Interstitial Cystitis Interstitial Cystitis (IC) is a syndrome characterized by bladder pain associated with urgency, frequency, nocturia, dysuria and sterile urine. The patho-physiology remains largely unclear. No universally, effective, treatment exists. Botulinum toxin-A (BTX-A) inhibits the release of acetylcholine at the presynaptic cholinergic junction resulting in temporally muscle relaxation and bladder desensitisation. We explore the effects of intravesical injections with BTX-A in the treatment of IC.Trade Name: Botoxresearch office urology VUmcNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
12Netherlands
6NCT00194610
(ClinicalTrials.gov)
May 200413/9/2005Botox as a Treatment for Interstitial Cystitis in WomenBotox (Botulinum Toxin A) as a Treatment for Interstitial Cystitis in Women: A Randomized Placebo Controlled TrialPainful Bladder Syndrome;Interstitial CystitisDrug: Botox;Other: normal salineUniversity of WashingtonPaul G. Allen Family FoundationCompleted18 YearsN/AFemale20Phase 4United States