23. Prion disease Clinical trials / Disease details


Clinical trials : 4 Drugs : 5 - (DrugBank : 2) / Drug target gene : 0 - Drug target pathway : 0

  
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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PhaseCountries
1EUCTR2010-022233-28-IT
(EUCTR)
20/06/201105/03/2012Fatal familial insomnia: preventive treatment with doxycycline of at risk individuals - Doxycycline in FFI individuals Subjects born between 1958 and 1969 belonging to the Treviso FFI family, tested previously for Prion D178N/129M mutation
MedDRA version: 14.1;Level: SOC;Classification code 10029205;Term: Nervous system disorders;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]
Trade Name: BASSADO
INN or Proposed INN: DOXYCYCLINE HYCLATE
IST. DI RICERCHE FARMACOLOG. M. NEGRINULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
Italy
2EUCTR2006-001858-27-IT
(EUCTR)
21/06/200612/04/2007A randomized, double-blind pilot study vs placebo for the evaluation of efficacy and tolerability of doxycline administered by oral route in patients affected by Creutzfeldt-Jakob disease. - NDA randomized, double-blind pilot study vs placebo for the evaluation of efficacy and tolerability of doxycline administered by oral route in patients affected by Creutzfeldt-Jakob disease. - ND Creutzfeldt-Jakob Disease.
MedDRA version: 9.1;Level: LLT;Classification code 10011384;Term: Creutzfeldt-Jakob disease
Trade Name: BASSADO 10CPS 100MG
INN or Proposed INN: Doxycycline
ISTITUTO NEUROLOGICO CARLO BESTANULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
Italy
3NCT00183092
(ClinicalTrials.gov)
April 200514/9/2005CJD (Creutzfeldt-Jakob Disease) Quinacrine StudyNovel Therapeutics For Prion Diseases: A Randomized, Double-blinded, Placebo-controlled Study of the Efficacy of Quinacrine in the Treatment of Sporadic Creutzfeldt-Jakob DiseaseCreutzfeldt-Jakob DiseaseDrug: Quinacrine;Drug: PlaceboUniversity of California, San FranciscoNational Institute on Aging (NIA)Completed18 YearsN/AAll69Phase 2United States
4NCT00104663
(ClinicalTrials.gov)
June 20043/3/2005PRION-1: Quinacrine for Human Prion DiseasePRION-1: Quinacrine for Human Prion Disease. A Partially Randomized Patient Preference Trial to Evaluate the Activity and Safety of Quinacrine in Human Prion DiseasePrion DiseaseDrug: QuinacrineMedical Research CouncilNULLCompleted12 YearsN/ABoth160N/AUnited Kingdom