240. Phenylketonuria Clinical trials / Disease details

Clinical trials : 143 / Drugs : 90 - (DrugBank : 10) / Drug target gene : 1 - Drug target pathways : 5

2 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04534842 (ClinicalTrials.gov)	August 25, 2020	24/8/2020	Efficacy and Safety of SYNB1618 and SYNB1934 in Adult Patients With Phenylketonuria	An Open-label Study of the Efficacy and Safety of SYNB1618 and SYNB1934 in Patients With Phenylketonuria (SynPheny-1)	Phenylketonuria	Drug: SYNB1618;Drug: SYNB1934	Synlogic	NULL	Completed	18 Years	N/A	All	20	Phase 2	United States
2	NCT03516487 (ClinicalTrials.gov)	April 17, 2018	11/4/2018	Safety and Tolerability of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria	A Phase 1/2a, First-in-human, Oral Single and Multiple Dose-escalation, Randomized, Double-blinded, Placebo-controlled Study of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria to Evaluate Safety, Tolerability, Kinetics, and Pharmacodynamics	Phenylketonuria;Healthy	Drug: SYNB1618;Drug: Placebo	Synlogic	NULL	Completed	18 Years	64 Years	All	70	Phase 1/Phase 2	United States