263. Cerebrotendinous xanthomatosis Clinical trials / Disease details

Clinical trials : 6 / Drugs : 11 - (DrugBank : 2) / Drug target genes : 2 - Drug target pathways : 4

4 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-JapicCTI-205157	03/8/2020	13/02/2020	An open-label study of FPF1011 in patients with cerebrotendinous xanthomatosis (phase 3)	An open-label study of FPF1011 in patients with cerebrotendinous xanthomatosis (phase 3)	Cerebrotendinous xanthomatosis	Intervention name : FPF1011 INN of the intervention : Chenodeoxycholic acid Dosage And administration ...	Fujimoto Pharmaceutical Corporation	NULL	recruiting	0		BOTH	5	Phase 3	Japan
2	NCT04270682 (ClinicalTrials.gov)	January 31, 2020	12/2/2020	Study to Evaluate Patients With Cerebrotendinous Xanthomatosis (RESTORE)	A Phase 3 Study to Evaluate the Effects of Chenodeoxycholic Acidin Adult and Pediatric Patients With ...	CTX	Drug: Blinded CDCA250 mg TID;Drug: Placebo;Drug: Open-Label CDCA250 mg TID;Drug: Rescue Medication C ...	Travere Therapeutics, Inc.	NULL	Recruiting	1 Month	N/A	All	12	Phase 3	United States;Brazil
3	NCT00018694 (ClinicalTrials.gov)	October 1999	3/7/2001	Cholestanol in Humans	Biologic Significance of Cholestanol in Man	Cerebrotendinous Xanthomatosis	Drug: Chenodeoxycholic Acid	Department of Veterans Affairs	NULL	Withdrawn	5 Years	80 Years	Both	0	N/A	United States
4	NCT00004346 (ClinicalTrials.gov)	January 1996	18/10/1999	Phase II Study of Cholesterol- and Cholestanol-Free Diet, Lovastatin, and Chenodeoxycholic Acidfor C ...	Effects of Diet and Medication in Patients With Cerebrotendinous Xanthomatosis (CTX)	Cerebrotendinous Xanthomatosis	Drug: chenodeoxycholic acid;Drug: lovastatin	National Center for Research Resources (NCRR)	Oregon Health and Science University	Recruiting	N/A	N/A	Both	5	Phase 2	United States

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