271. Ankylosing spondylitis Clinical trials / Disease details

Clinical trials : 574 / Drugs : 359 - (DrugBank : 68) / Drug target genes : 41 - Drug target pathways : 146

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05527444 (ClinicalTrials.gov)	March 15, 2022	6/5/2022	The Clinical Efficacy and the Changes of Immune Cells Subsets With Bioagents in Ankylosing Spondylit ...	The Clinical Efficacy and the Changes of Immune Cells Subsets With Bioagents in Ankylosing Spondylit ...	Ankylosing Spondylitis	Drug: Secukinumab 150 mg/ml;Drug: Adalimumab Ab;Drug: NSAID;Drug: Thalidomide Pill	Qilu Hospital of Shandong University	NULL	Recruiting	18 Years	65 Years	All	100	Phase 4	China
2	EUCTR2020-004284-98-GR (EUCTR)	15/07/2021	05/04/2021	Secukinumab open label roll-over extension protocol	An open-label, multi-center protocol for patients who have completed a previous Novartis sponsored S ...	Psoriatic Arthritis, Ankylosing Spondylitis, non-radiographic axial spondyloarthritis, Severe Chroni ...	Trade Name: Cosentyx Product Name: Secukinumab Product Code: AIN457 INN or Proposed INN: secukinumab Oth ...	Novartis Pharma AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	628	Phase 4	United States;Czechia;Greece;Spain;Guatemala;Russian Federation;Colombia;India;Egypt;Czech Republic; ...
3	EUCTR2020-004284-98-BG (EUCTR)	05/02/2021	29/01/2021	Secukinumab open label roll-over extension protocol	An open-label, multi-center protocol for patients who have completed a previous Novartis sponsored S ...	Psoriatic Arthritis, Ankylosing Spondylitis, non-radiographic axial spondyloarthritis, Severe Chroni ...	Trade Name: Cosentyx Product Name: Secukinumab Product Code: AIN457 INN or Proposed INN: secukinumab Oth ...	Novartis Pharma AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	628	Phase 4	United States;Czechia;Greece;Spain;Guatemala;Turkey;Russian Federation;Colombia;India;Egypt;Czech Re ...
4	EUCTR2019-001177-90-SE (EUCTR)	30/06/2020	17/12/2019	Study to demonstrate the efficacy, safety and tolerability of an intravenous(i.v.) regimen of secuki ...	A randomized, double-blind, placebo-controlled, parallel group, phase IIImulticenter study of intrav ...	Axial Spondyloarthritis MedDRA version: 21.1;Level: PT;Classification code 10071400;Term: Axial spon ...	Product Name: Secukinumab Product Code: AIN457 INN or Proposed INN: Secukinumab Other descriptive name: ...	Novartis Pharma AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	500	Phase 3	United States;Czechia;Philippines;Greece;Thailand;Guatemala;Turkey;Russian Federation;Colombia;Italy ...
5	EUCTR2019-001177-90-IT (EUCTR)	06/05/2020	19/05/2021	Study to demonstrate the efficacy, safety and tolerability of an intravenous(i.v.) regimen of secuki ...	A randomized, double-blind, placebo-controlled, parallel group, phase IIImulticenter study of intrav ...	Axial Spondyloarthritis MedDRA version: 21.1;Level: PT;Classification code 10071400;Term: Axial spon ...	Product Name: Secukinumab Product Code: AIN457 INN or Proposed INN: Secukinumab Other descriptive name: ...	Novartis Pharma AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	500	Phase 3	United States;Czechia;Philippines;Greece;Thailand;Guatemala;Turkey;Russian Federation;Colombia;Italy ...
6	EUCTR2019-001177-90-BG (EUCTR)	07/04/2020	12/02/2020	Study to demonstrate the efficacy, safety and tolerability of an intravenous(i.v.) regimen of secuki ...	A randomized, double-blind, placebo-controlled, parallel group, phase IIImulticenter study of intrav ...	Axial Spondyloarthritis MedDRA version: 21.1;Level: PT;Classification code 10071400;Term: Axial spon ...	Product Name: Secukinumab Product Code: AIN457 INN or Proposed INN: Secukinumab Other descriptive name: ...	Novartis Pharma AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	500	Phase 3	United States;Philippines;Czechia;Greece;Thailand;Guatemala;Turkey;Russian Federation;Colombia;Italy ...
7	EUCTR2019-001177-90-CZ (EUCTR)	20/02/2020	19/12/2019	Study to demonstrate the efficacy, safety and tolerability of an intravenous(i.v.) regimen of secuki ...	A randomized, double-blind, placebo-controlled, parallel group, phase IIImulticenter study of intrav ...	Axial Spondyloarthritis MedDRA version: 21.1;Level: PT;Classification code 10071400;Term: Axial spon ...	Product Name: Secukinumab Product Code: AIN457 INN or Proposed INN: Secukinumab Other descriptive name: ...	Novartis Pharma AG	NULL	Not Recruiting			Female: yes Male: yes	500	Phase 3	United States;Czechia;Philippines;Greece;Thailand;Guatemala;Turkey;Russian Federation;Colombia;Italy ...
8	EUCTR2019-001177-90-GR (EUCTR)	23/01/2020	13/11/2019	Study to demonstrate the efficacy, safety and tolerability of an intravenous(i.v.) regimen of secuki ...	A randomized, double-blind, placebo-controlled, parallel group, phase IIImulticenter study of intrav ...	Axial Spondyloarthritis MedDRA version: 21.1;Level: PT;Classification code 10071400;Term: Axial spon ...	Product Name: Secukinumab Product Code: AIN457 INN or Proposed INN: Secukinumab Other descriptive name: ...	Novartis Pharma AG	NULL	Not Recruiting			Female: yes Male: yes	500	Phase 3	United States;Czechia;Philippines;Greece;Thailand;Guatemala;Turkey;Russian Federation;Colombia;Italy ...
9	EUCTR2019-001177-90-BE (EUCTR)	21/01/2020	22/10/2019	Study to demonstrate the efficacy, safety and tolerability of an intravenous(i.v.) regimen of secuki ...	A randomized, double-blind, placebo-controlled, parallel group, phase IIImulticenter study of intrav ...	Axial Spondyloarthritis MedDRA version: 21.1;Level: PT;Classification code 10071400;Term: Axial spon ...	Product Name: Secukinumab Product Code: AIN457 INN or Proposed INN: Secukinumab Other descriptive name: ...	Novartis Pharma AG	NULL	Not Recruiting			Female: yes Male: yes	500	Phase 3	Thailand;Guatemala;Turkey;Russian Federation;Colombia;Italy;India;Egypt;Czech Republic;Poland;Belgiu ...
10	NCT04156620 (ClinicalTrials.gov)	December 11, 2019	8/10/2019	Study to Demonstrate the Efficacy, Safety and Tolerability of an Intravenous Regimen of SecukinumabC ...	A Randomized, Double-blind, Placebo-controlled, Parallel Group, Phase III Multicenter Study of Intra ...	Ankylosing Spondylitis	Drug: Secukinumab;Drug: Placebo	Novartis Pharmaceuticals	NULL	Completed	18 Years	N/A	All	527	Phase 3	United States;Belgium;Brazil;Bulgaria;Colombia;Czechia;Greece;Guatemala;India;Italy;Korea, Republic ...

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