271. Ankylosing spondylitis Clinical trials / Disease details

Clinical trials : 574 / Drugs : 359 - (DrugBank : 68) / Drug target genes : 41 - Drug target pathways : 146

17 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04876781 (ClinicalTrials.gov)	January 12, 2022	20/4/2021	Korean Post-marketing Surveillance for Xeljanz XR	Korean Post-marketing Surveillance for Xeljanz XR (Registered)	Active Moderate to Severe Rheumatoid Arthritis;Active Ankylosing Spondylitis	Drug: Tofacitinib XR	Pfizer	NULL	Recruiting	18 Years	N/A	All	200		Korea, Republic of
2	EUCTR2018-000226-58-DE (EUCTR)	18/10/2018	16/05/2018	A Phase 3 Study Of The Efficacy And Safety Of TofacitinibIn Patients With Active Ankylosing Spondyli ...	A Phase 3, Randomized, Double Blind, Placebo Controlled, Study Of The Efficacy And Safety Of Tofacit ...	Ankylosing spondylitis (AS) MedDRA version: 20.0;Level: PT;Classification code 10002556;Term: Ankylo ...	Product Name: Tofacitinib 5 mg Product Code: CP -690,550 INN or Proposed INN: Tofacitinib Other descripti ...	Pfizer Inc., 235 East 42nd Street, New York, NY 10017	NULL	Not Recruiting			Female: yes Male: yes	240	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United States;Taiwan;Slovakia;Spain;Ukraine;Turkey;Austria;Russian Federation;Israel;United Kingdom; ...
3	EUCTR2018-000226-58-GB (EUCTR)	13/08/2018	15/05/2018	A Phase 3 Study Of The Efficacy And Safety Of TofacitinibIn Patients With Active Ankylosing Spondyli ...	A Phase 3, Randomized, Double Blind, Placebo Controlled, Study Of The Efficacy And Safety Of Tofacit ...	Ankylosing spondylitis (AS) MedDRA version: 20.0;Level: PT;Classification code 10002556;Term: Ankylo ...	Product Name: Tofacitinib 5 mg Product Code: CP -690,550 INN or Proposed INN: Tofacitinib Other descripti ...	Pfizer Inc., 235 East 42nd Street, New York, NY 10017	NULL	Not Recruiting			Female: yes Male: yes	240	Phase 3	United States;Taiwan;Slovakia;Spain;Ukraine;Turkey;Austria;Russian Federation;Israel;United Kingdom; ...
4	EUCTR2018-000226-58-BG (EUCTR)	07/08/2018	31/05/2018	A Phase 3 Study Of The Efficacy And Safety Of TofacitinibIn Patients With Active Ankylosing Spondyli ...	A Phase 3, Randomized, Double Blind, Placebo Controlled, Study Of The Efficacy And Safety Of Tofacit ...	Ankylosing spondylitis (AS) MedDRA version: 20.0;Level: PT;Classification code 10002556;Term: Ankylo ...	Product Name: Tofacitinib 5 mg Product Code: CP -690,550 INN or Proposed INN: Tofacitinib Other descripti ...	Pfizer Inc., 235 East 42nd Street, New York, NY 10017	NULL	Not Recruiting			Female: yes Male: yes	240	Phase 3	United States;Taiwan;Slovakia;Spain;Ukraine;Turkey;Austria;Russian Federation;Israel;United Kingdom; ...
5	EUCTR2018-000226-58-FR (EUCTR)	12/07/2018	23/04/2018	A Phase 3 Study Of The Efficacy And Safety Of TofacitinibIn Patients With Active Ankylosing Spondyli ...	A Phase 3, Randomized, Double Blind, Placebo Controlled, Study Of The Efficacy And Safety Of Tofacit ...	Ankylosing spondylitis (AS) MedDRA version: 20.0;Level: PT;Classification code 10002556;Term: Ankylo ...	Trade Name: Xeljanz Product Name: Tofacitinib 5 mg Product Code: CP -690,550 INN or Proposed INN: Tofacit ...	Pfizer Inc., 235 East 42nd Street, New York, NY 10017	NULL	Not Recruiting			Female: yes Male: yes	240	Phase 3	United States;Taiwan;Slovakia;Spain;Ukraine;Turkey;Austria;Russian Federation;Israel;United Kingdom; ...
6	EUCTR2018-000226-58-CZ (EUCTR)	09/07/2018	04/05/2018	A Phase 3 Study Of The Efficacy And Safety Of TofacitinibIn Patients With Active Ankylosing Spondyli ...	A Phase 3, Randomized, Double Blind, Placebo Controlled, Study Of The Efficacy And Safety Of Tofacit ...	Ankylosing spondylitis (AS) MedDRA version: 20.0;Level: PT;Classification code 10002556;Term: Ankylo ...	Trade Name: Xeljanz Product Name: Tofacitinib 5 mg Product Code: CP -690,550 INN or Proposed INN: Tofacit ...	Pfizer Inc.	NULL	Not Recruiting			Female: yes Male: yes	240	Phase 3	United States;Taiwan;Slovakia;Spain;Ukraine;Turkey;Austria;Russian Federation;Israel;United Kingdom; ...
7	EUCTR2018-000226-58-AT (EUCTR)	06/07/2018	14/05/2018	A Phase 3 Study Of The Efficacy And Safety Of TofacitinibIn Patients With Active Ankylosing Spondyli ...	A Phase 3, Randomized, Double Blind, Placebo Controlled, Study Of The Efficacy And Safety Of Tofacit ...	Ankylosing spondylitis (AS) MedDRA version: 20.0;Level: PT;Classification code 10002556;Term: Ankylo ...	Product Name: Tofacitinib 5 mg Product Code: CP -690,550 INN or Proposed INN: Tofacitinib Other descripti ...	Pfizer Inc., 235 East 42nd Street, New York, NY 10017	NULL	Not Recruiting			Female: yes Male: yes	240	Phase 3	United States;Taiwan;Slovakia;Spain;Ukraine;Turkey;Austria;Russian Federation;Israel;United Kingdom; ...
8	EUCTR2018-000226-58-ES (EUCTR)	04/07/2018	09/05/2018	A Phase 3 Study Of The Efficacy And Safety Of TofacitinibIn Patients With Active Ankylosing Spondyli ...	A Phase 3, Randomized, Double Blind, Placebo Controlled, Study Of The Efficacy And Safety Of Tofacit ...	Ankylosing spondylitis (AS) MedDRA version: 20.0;Level: PT;Classification code 10002556;Term: Ankylo ...	Trade Name: Xeljanz Product Name: Tofacitinib 5 mg Product Code: CP -690,550 INN or Proposed INN: Tofacit ...	Pfizer Inc., 235 East 42nd Street, New York, NY 10017	NULL	Not Recruiting			Female: yes Male: yes	240	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United States;Taiwan;Slovakia;Spain;Ukraine;Turkey;Austria;Russian Federation;Israel;United Kingdom; ...
9	EUCTR2018-000226-58-HU (EUCTR)	26/06/2018	26/04/2018	A Phase 3 Study Of The Efficacy And Safety Of TofacitinibIn Patients With Active Ankylosing Spondyli ...	A Phase 3, Randomized, Double Blind, Placebo Controlled, Study Of The Efficacy And Safety Of Tofacit ...	Ankylosing spondylitis (AS) MedDRA version: 20.0;Level: PT;Classification code 10002556;Term: Ankylo ...	Trade Name: Xeljanz Product Name: Tofacitinib 5 mg Product Code: CP -690,550 INN or Proposed INN: Tofacit ...	Pfizer Inc., 235 East 42nd Street, New York, NY 10017	NULL	Not Recruiting			Female: yes Male: yes	240	Phase 3	United States;Taiwan;Slovakia;Spain;Ukraine;Turkey;Austria;Russian Federation;Israel;United Kingdom; ...
10	NCT03502616 (ClinicalTrials.gov)	June 7, 2018	11/4/2018	Efficacy and Safety of Tofacitinib in Subjects With Active Ankylosing Spondylitis (AS)	A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, STUDY OF THE EFFICACY AND SAFETY OF TOFACIT ...	Ankylosing Spondylitis	Drug: Tofacitinib	Pfizer	NULL	Completed	18 Years	N/A	All	270	Phase 3	United States;Australia;Bulgaria;Canada;China;Czechia;France;Hungary;Israel;Korea, Republic of;Polan ...

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