296. Biliary atresia Clinical trials / Disease details


Clinical trials : 71 Drugs : 70 - (DrugBank : 39) / Drug target genes : 35 - Drug target pathways : 60

  
9 trials found
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1ChiCTR2200059705
2022-05-012022-05-08Machine Learning Based on Sonographic Gallbladder Images in Prenatal Diagnosis of Biliary AtresiaMachine Learning Based on Sonographic Gallbladder Images in Prenatal Diagnosis of Biliary Atresia Biliary atresiaGold Standard:Surgical exploration, puncture biopsy, intraoperative cholangiography, or percutaneous cholecystography ;Index test:Intelligent prenatally diagnostic system based on sonographic gallbladder images;Shengjing Hospital of China Medical UniversityNULLPendingFemaleTarget condition:2000;Difficult condition:0China
2ChiCTR2200055459
2022-02-012022-01-10Establishment of a diagnostic model of biliary atresia ultrasound combined with MMP-7: a multicenter diagnostic accuracy studyEstablishment of a diagnostic model of biliary atresia ultrasound combined with MMP-7: a multicenter diagnostic accuracy study Biliary atresiaGold Standard:Biliary tract exploration and liver pathology.;Index test:MMP-7, ultrasound, MMP-7 and ultrasound combined diagnostic model.;Pediatric Hospital Affiliated to Fudan UniversityNULLRecruitingBothTarget condition:150;Difficult condition:150China
3ChiCTR2100053800
2021-12-132021-11-29Multimodal Magnetic Resonance Imaging for Evaluating the Developmental State of Bile Ducts and the Degree of Hepatic Fibrosis in Children with Biliary AtresiaMultimodal Magnetic Resonance Imaging for Evaluating the Developmental State of Bile Ducts and the Degree of Hepatic Fibrosis in Children with Biliary Atresia Biliary AtresiaGold Standard:Intraoperative cholangiography is often considered the diagnostic gold standard for biliary atresia. Blood biochemical examination is used as a reference standard for evaluating liver fibrosis.;Index test:Multimodal Magnetic Resonance Imaging;Children's Hospital of Chongqing Medical UniversityNULLRecruitingBothTarget condition:100;Difficult condition:0China
4ChiCTR2100044533
2021-06-012021-03-23Multicenter study of non-invasive diagnostic scoring system for biliary atresiaMulticenter study of non-invasive diagnostic scoring system for biliary atresia Biliary atresiaGold Standard:Intraoperative cholangiography;Index test:Non-invasive diagnostic scoring system for biliary atresia (Biochemicaltests, blood routine, CRP, blood ammonia, AFP, hepatobiliary B ultrasound);Children's Hospital Affiliated to Zhejiang University Medical CollegeNULLRecruitingBothTarget condition:200;Difficult condition:0China
5ChiCTR2000032983
2020-08-012020-05-17Development of Biomarkers for Biliary Atresia and Establishment of Artificial Intelligence Diagnostic ModelDevelopment of Biomarkers for Biliary Atresia and Establishment of Artificial Intelligence Diagnostic Model Biliary atresiaGold Standard:Cholangiography combined with liver biopsy;Index test:MMP7;bile acid profile;Children's Hospital of Fudan UniversityNULLRecruitingBothTarget condition:600;Difficult condition:600China
6ChiCTR2000034127
2020-07-202020-06-25Application of MMP-7 in early diagnosis of neonatal biliary atresiaApplication of MMP-7 in early diagnosis of neonatal biliary atresia Biliary atresia diseaseGold Standard:Laparoscopic cholangiography;Index test:Serum MMP-7;Department of Pediatric Surgery, Union Hospital Affiliated to Tongji Medical College of Huazhong University of Science and TechnologyNULLPending0.1BothTarget condition:300;Difficult condition:0China
7ChiCTR1800019866
2019-01-012018-12-02Development and validation of novel diagnostic model for biliary atresiaDevelopment and validation of novel diagnostic model for biliary atresia: a multicenter diagnostic test biliary atresiaGold Standard:cholangiography combined with liver biopsy;Index test:Nomogram;Children's Hospital of Fudan UniversityNULLPendingBothTarget condition:1000;Difficult condition:200China
8ChiCTR1800017428
2018-08-152018-07-30Machine learning based on the gallbladder morphology for screening biliary atresia among infants with conjugated hyperbilirubinemiaMachine learning based on the gallbladder morphology for screening biliary atresia among infants with conjugated hyperbilirubinemia Biliary atresiaGold Standard:Surgical exploration, puncture biopsy, intraoperative cholangiography or percutaneous cholecystography;Index test:machine learning based on the gallbladder morphology;Department of Medical Ultrasonics, the First Affiliated Hospital of Sun Yat-sen UniversityNULLPendingBothTarget condition:500;Difficult condition:100China
9ChiCTR-DPD-15005847
2014-11-192015-01-19Evidence-based guideline of diagnosis and treatment of biliary atresiaEvidence-based guideline of diagnosis and treatment of biliary atresia biliary atresiaGold Standard:;Index test:;Children's Hospital of Fudan UniversityNULLPending018BothTarget condition:0;Difficult condition:0I (Phase 1 study)China