299. Cystic fibrosis Clinical trials / Disease details

Clinical trials : 1,695 / Drugs : 1,527 - (DrugBank : 268) / Drug target genes : 111 - Drug target pathways : 174

16 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05276960 (ClinicalTrials.gov)	February 22, 2022	21/2/2022	Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum vitD Levels in Pediatric Patients With CF	A Randomized, Double-blind Study of the Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum Vitamin D Levels in Pediatric Patients With Cystic Fibrosis	Vitamin D Deficiency;Cystic Fibrosis;Bone Density, Low;Inflammation Chronic;Cystic Fibrosis in Children;Cystic Fibrosis Pulmonary Exacerbation	Drug: Cholecalciferol Pill	Hospital Infantil de Mexico Federico Gomez	NULL	Recruiting	5 Years	18 Years	All	40	Phase 4	Mexico
2	NCT04118010 (ClinicalTrials.gov)	March 13, 2020	4/10/2019	Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis	Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis	Cystic Fibrosis;Dysbiosis	Drug: Vitamin D3;Drug: Placebo vitamin D3;Drug: Inulin;Drug: Placebo Inulin	Emory University	NULL	Completed	18 Years	N/A	All	40	Phase 4	United States
3	NCT03734744 (ClinicalTrials.gov)	June 17, 2019	6/11/2018	PK/PD of Vitamin D3 in Adults With CF	A Pilot Study Evaluating Single, High-dose Pharmacokinetics/Pharmacodynamics of Vitamin D3 in CF	Vitamin D Deficiency;Cystic Fibrosis	Dietary Supplement: Vitamin D3	University of Southern California	NULL	Terminated	18 Years	N/A	All	6	N/A	United States
4	NCT04411901 (ClinicalTrials.gov)	March 1, 2018	22/5/2020	The Role of Vitamin D3 in Pediatric Bronchiectasis Severity	The Role of Vitamin D3 in Pediatric Bronchiectasis Severity( CF Versus Non CF Bronchioectasis)	Cystic Fibrosis and Non CF Bronchiectasis	Drug: Cholecalciferol (vitaminD3)	Heba Omara	NULL	Completed	1 Year	17 Years	All	40	Phase 2/Phase 3	Egypt
5	NCT02613884 (ClinicalTrials.gov)	November 2016	20/11/2015	Safety, Efficacy, and Feasibility of High-dose Cholecalciferol in Pediatric Patients With Cystic Fibrosis	Safety, Efficacy, and Feasibility of High-dose Cholecalciferol in Pediatric Patients With Cystic Fibrosis	Vitamin D Deficiency	Drug: Treatment	Johns Hopkins All Children's Hospital	NULL	Completed	36 Months	18 Years	All	30	Phase 2	United States
6	NCT02589444 (ClinicalTrials.gov)	December 2015	20/10/2015	Vitamin D and Microbiota in Cystic Fibrosis	Pilot Study Evaluating the Role of Vitamin D Repletion on Gut and Lung Microbiota in Cystic Fibrosis	Vitamin D Deficiency;Cystic Fibrosis	Dietary Supplement: High-Dose Vitamin D3;Other: Stool Sample;Other: Sputum Sample;Other: Sham Comparator;Procedure: Blood draw	Emory University	NULL	Completed	18 Years	N/A	All	41	N/A	United States
7	NCT02507843 (ClinicalTrials.gov)	January 2015	22/7/2015	Vitamin D as an Adjunctive Treatment in Patients With Non-Cystic Fibrosis Bronchiectasis	Vitamin D as an Adjunctive Treatment in Patients With Non-Cystic Fibrosis Bronchiectasis: a Double-blind Randomised Controlled Trial	Bronchiectasis	Drug: Cholecalciferol;Drug: Placebo	Shanghai Pulmonary Hospital, Shanghai, China	NULL	Recruiting	18 Years	N/A	Both	200	Phase 4	China
8	NCT02043717 (ClinicalTrials.gov)	January 2014	12/1/2014	Increased Vitamin D Reduces Pulmonary Exacerbations in CF	Increasing Vitamin D Serum Levels Reduces Pulmonary Exacerbations in Patients With Cystic Fibrosis	Cystic Fibrosis	Dietary Supplement: Vitamin D	Hadassah Medical Organization	NULL	Completed	4 Years	N/A	All	90	N/A	Israel
9	NCT01880346 (ClinicalTrials.gov)	October 2013	12/6/2013	Comparison of Absorption of Vitamin D in Cystic Fibrosis	Vehicles for the Absorption of Vitamin D in Cystic Fibrosis: Comparison of Powder vs Oil	Cystic Fibrosis	Dietary Supplement: Vitamin D Powder;Dietary Supplement: Vitamin D Oil	Emory University	NULL	Completed	18 Years	59 Years	Both	17	Phase 4	United States
10	NCT01426256 (ClinicalTrials.gov)	October 2011	29/8/2011	Vitamin D for Enhancing the Immune System in Cystic Fibrosis (DISC Study)	Vitamin D for Enhancing the Immune System in Cystic Fibrosis	Cystic Fibrosis;Respiratory Tract Infections	Dietary Supplement: Cholecalciferol	Emory University	Cystic Fibrosis Foundation Therapeutics	Completed	16 Years	N/A	All	91	Phase 3	United States
11	NCT01222273 (ClinicalTrials.gov)	September 2010	14/10/2010	Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis	Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis	Cystic Fibrosis;Allergic Bronchopulmonary Aspergillosis	Dietary Supplement: cholecalciferol (Vitamin D3)	University of Pittsburgh	National Heart, Lung, and Blood Institute (NHLBI)	Completed	12 Years	N/A	All	7	N/A	United States
12	NCT01321905 (ClinicalTrials.gov)	April 2010	23/3/2011	Prospective Intervention Study on Vitamin D in Patients With Cystic Fibrosis	5-month Pilot Intervention Study on Vitamin D in Patients With Cystic Fibrosis	Cystic Fibrosis	Dietary Supplement: Supplementation with vitamin D2/D3	Karolinska Institutet	Stockholm County Council, Sweden;Swedish Cystic Fibrosis Association	Recruiting	6 Years	N/A	Both	15	Phase 2	Sweden
13	NCT00685971 (ClinicalTrials.gov)	December 2008	27/5/2008	Cholecalciferol for Vitamin D in Adult Cystic Fibrosis (CF) Patients	Randomized Placebo-Controlled Trial of Cholecalciferol for Vitamin D Deficiency in Adults With Cystic Fibrosis	Cystic Fibrosis;Vitamin D Deficiency	Dietary Supplement: 5000 IU of cholecalciferol;Dietary Supplement: placebo	St. Michael's Hospital, Toronto	NULL	Completed	18 Years	N/A	Both	200	N/A	Canada
14	NCT00788138 (ClinicalTrials.gov)	October 2008	7/11/2008	Effects of Vitamin D Supplementation on Lung Function in an Acute Pulmonary Exacerbation of Cystic Fibrosis		Cystic Fibrosis	Dietary Supplement: Vitamin D3;Dietary Supplement: Placebo	Emory University	NULL	Completed	18 Years	70 Years	Both	30	N/A	United States
15	NCT00762918 (ClinicalTrials.gov)	March 2008	26/9/2008	Vitamin D3 for the Treatment of Low Vitamin D in Cystic Fibrosis	Vitamin D and Its Non-Classic Roles in Cystic Fibrosis	Cystic Fibrosis;Vitamin D Deficiency	Dietary Supplement: cholecalciferol	Children's Hospital of Philadelphia	NULL	Withdrawn	10 Years	25 Years	Both	0	Phase 3	United States
16	NCT00450073 (ClinicalTrials.gov)	November 2006	19/3/2007	Improving Vitamin D Status In Cystic Fibrosis	Desktop Tanning Unit to Improve Vitamin D Status in Patients With Cystic Fibrosis and Short Bowel Syndrome: A Pilot Study	Cystic Fibrosis	Drug: ergocalciferol (vitamin D2);Device: Sperti Del Sol Lamp;Drug: Vitamin D3	Atlanta VA Medical Center	Emory University	Completed	18 Years	60 Years	All	30	N/A	United States