300. IgG4-related disease Clinical trials / Disease details
Clinical trials : 40 / Drugs : 47 - (DrugBank : 21) / Drug target genes : 18 - Drug target pathways : 141
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05746689 (ClinicalTrials.gov) | March 1, 2023 | 13/2/2023 | Study of Sirolimus in IgG4-related Disease | Combination Therapy of Sirolimus and Glucocorticoids for the Maintenance of Remission in Patients With IgG4-related Disease | IgG4-related Disease | Drug: Sirolimus | Peking University International Hospital | NULL | Not yet recruiting | 18 Years | 80 Years | All | 20 | N/A | NULL |
| 2 | NCT04520451 (ClinicalTrials.gov) | August 22, 2020 | 11/8/2020 | Open Label Two-Arm Study to Evaluate Rilzabrutinib in IgG4-Related Disease Patients | An Open Label, Two-Arm Study to Evaluate the Effect of Rilzabrutinib (PRN1008/SAR444671) on Safety and Disease Activity in Patients With IgG4-Related Disease | Immunoglobulin G4 Related Disease | Drug: rilzabrutinib;Drug: Glucocorticoids | Principia Biopharma, a Sanofi Company | Massachusetts General Hospital | Recruiting | 18 Years | N/A | All | 25 | Phase 2 | United States;Canada |
| 3 | ChiCTR2000028918 | 2020-01-01 | 2020-01-07 | A randomized, double-blind controlled study of glucocorticoids combination with thalidomide in the treatment of IgG4-related diseases | Efficacy and safety of thalidomide in IgG4-related diseases | IgG4 related disease | control group:prednison combined with placebo;experimental group:prednison combined with thalidomide; | Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology | NULL | Recruiting | 18 | 80 | Both | control group:51;experimental group:51; | Phase 4 | China |
| 4 | NCT01758393 (ClinicalTrials.gov) | December 2012 | 24/12/2012 | Glucocorticoids in Patients With IgG4-RD | A Randomized Trial of Glucocorticoids in Patients With IgG4-Related Disease | IgG4-related Disease | Drug: Prednisone | Peking Union Medical College Hospital | NULL | Recruiting | 18 Years | 70 Years | Both | 40 | Phase 2/Phase 3 | China |