40. Takayasu arteritis Clinical trials / Disease details

Clinical trials : 24 / Drugs : 40 - (DrugBank : 18) / Drug target genes : 23 - Drug target pathways : 110

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05151848 (ClinicalTrials.gov)	January 5, 2022	6/11/2021	Comparison of Adalimumab and Tofacitinib in the Treatment of Active Takayasu Arteritis	An Open-label,Randomized, Controlled, Multicenter Study of Adalimumab and Tofacitinib in the Treatme ...	Takayasu Arteritis	Drug: Adalimumab Injection;Drug: Tofacitinib 5 MG	Chinese SLE Treatment And Research Group	NULL	Recruiting	18 Years	65 Years	All	100	Phase 4	China
2	JPRN-jRCT2061210007	13/10/2021	28/05/2021	A Study of Ustekinumab in Participants With Takayasu Arteritis (TAK)	A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study of Usteki ...	Takayasu Arteritis	Ustekinumab Participants will receive IV infusion and SC injection of ustekinumab. Placebo Participants ...	Nishikawa Kazuko	NULL	Recruiting	>= 18age old	<= 75age old	Both	50	Phase 3	Japan
3	NCT04882072 (ClinicalTrials.gov)	September 15, 2021	10/5/2021	A Study of Ustekinumab in Participants With Takayasu Arteritis (TAK)	A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study of Usteki ...	Takayasu Arteritis	Drug: Ustekinumab;Other: Placebo;Drug: Glucorticoid Taper Regimen	Janssen Pharmaceutical K.K.	NULL	Active, not recruiting	15 Years	75 Years	All	14	Phase 3	Japan
4	NCT05168475 (ClinicalTrials.gov)	July 14, 2021	9/12/2021	Biologics in Refractory Vasculitis	Biologics in Refractory Vasculitis (BIOVAS): A Pragmatic, Randomised, Double-blind, Placebo-controll ...	Giant Cell Arteritis;Takayasu Arteritis;Cogan Syndrome;Relapsing Polychondritis;Cryoglobulinemic Vas ...	Biological: Rituximab;Biological: Infliximab;Biological: Tocilizumab	Cambridge University Hospitals NHS Foundation Trust	NULL	Recruiting	5 Years	N/A	All	140	Phase 2	United Kingdom
5	NCT04564001 (ClinicalTrials.gov)	September 2020	21/9/2020	Multicentre, Randomized, Prospective Trial Evaluating the Efficacy and Safety of Infliximab to Tocil ...	Multicentre, Randomized, Prospective Trial Evaluating the Efficacy and Safety of Infliximab to Tocil ...	Takayasu Arteritis	Drug: Infliximab;Drug: Tocilizumab	Assistance Publique - Hôpitaux de Paris	NULL	Not yet recruiting	18 Years	N/A	All	50	Phase 2	NULL
6	NCT04300686 (ClinicalTrials.gov)	March 1, 2020	5/3/2020	A Pilot Study in Severe Patients With Takayasu Arteritis.	A Pilot Study in the Treatment of Severe Patients With Takayasu ArteritisWith Tocilizumab and Adalim ...	Takayasu Arteritis;Tocilizumab;Adalimumab;Treatment	Biological: Tocilizumab;Biological: Adalimumab	Shanghai Zhongshan Hospital	NULL	Recruiting	14 Years	100 Years	All	40	Phase 4	China
7	NCT04299971 (ClinicalTrials.gov)	March 1, 2020	5/3/2020	Efficiency of Methotrexate and Tofacitinib in Mild and Moderate Patients	Randomized Open-label Study in Mild and Moderate Patients With Takayasu ArteritisBetween Methotrexat ...	Takayasu Arteritis;Methotrexate;Inhibition;Treatment	Drug: Methotrexate Tablets;Drug: Tofacitinib tablet	Shanghai Zhongshan Hospital	NULL	Recruiting	14 Years	100 Years	All	130	Phase 4	China
8	NCT04161898 (ClinicalTrials.gov)	February 4, 2020	12/11/2019	A Study to Evaluate the Efficacy and Safety of Upadacitinib in Participants With Takayasu Arteritis( ...	A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy ...	Takayasu Arteritis (TAK)	Drug: Upadacitinib;Drug: Placebo for Upadacitinib;Drug: Prednisolone	AbbVie	NULL	Recruiting	15 Years	N/A	All	56	Phase 3	Argentina;Brazil;China;Japan;Korea, Republic of;Turkey
9	EUCTR2018-003753-13-FR (EUCTR)	19/03/2019	13/12/2018	INTOReTAK : INfliximab and TOcilizumab in Refractory/relapsing TAKayasu arteritis	Multicentre, randomized, prospective trial comparing the efficacy and safety of Infliximab to tocili ...	Patients with refractory or relapsing Takayasu Arteritisdesease;Therapeutic area: Analytical, Diagno ...	Trade Name: RoActemra 20mg/ml Product Name: Tocilizumab INN or Proposed INN: Tocilizumab Other descripti ...	ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	50	Phase 3	France
10	NCT03482479 (ClinicalTrials.gov)	February 4, 2019	22/3/2018	Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis	Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis	Eosinophilic Granulomatosis With Polyangiitis (EGPA);Churg-Strauss Syndrome (CSS);Giant Cell Arterit ...	Drug: Naltrexone Hydrochloride;Other: Placebo Comparator	University of Pennsylvania	NULL	Recruiting	18 Years	N/A	All	36	Phase 2	United States

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