41. Giant cell arteritis Clinical trials / Disease details
Clinical trials : 131 / Drugs : 139 - (DrugBank : 36) / Drug target genes : 33 - Drug target pathways : 125
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT05623592 (ClinicalTrials.gov) | November 23, 2022 | 8/11/2022 | Methotrexate as Remission Maintenance Therapy After Remission-Induction With Tocilizumab and Glucocorticoids in Giant Cell Arteritis | A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy of Methotrexate as Remission Maintenance Therapy After Remission-Induction Therapy With Tocilizumab and Glucocorticoids in Subjects With Giant Cell Arteritis | Giant Cell Arteritis | Drug: Methotrexate;Drug: Sodium chloride | University of Bonn | NULL | Recruiting | 18 Years | N/A | All | 40 | Phase 2 | Germany |
2 | NCT03745586 (ClinicalTrials.gov) | December 1, 2018 | 6/11/2018 | Giant Cell Arteritis Treatment With Ultra-short Glucocorticoids and Tocilizumab | Giant Cell Arteritis Treatment With Ultra-short Glucocorticoids and Tocilizumab | Giant Cell Arteritis | Drug: Tocilizumab;Drug: Glucocorticoids | University Hospital Inselspital, Berne | NULL | Completed | 50 Years | N/A | All | 18 | Phase 1/Phase 2 | Switzerland;Italy |
3 | NCT01450137 (ClinicalTrials.gov) | September 2011 | 3/10/2011 | Tocilizumab for Patients With Giant Cell Arteritis | A Phase II, Randomized, Double-blind, Placebo Controlled Study of Tocilizumab in Patients With Giant Cell Arteritis | Giant Cell Arteritis | Drug: Tocilizumab + Glucocorticoids (GCs);Drug: Placebo + Glucocorticoids (GCs) | University Hospital Inselspital, Berne | University of Bern;Roche Pharma AG | Completed | 50 Years | N/A | All | 30 | Phase 2 | Switzerland |
4 | NCT00004686 (ClinicalTrials.gov) | February 1994 | 24/2/2000 | Phase II Randomized Study of Glucocorticoids With or Without Methotrexate for Treatment of Giant Cell Arteritis | Giant Cell Arteritis | Drug: methotrexate;Drug: prednisone | The Cleveland Clinic | NULL | Completed | 50 Years | N/A | Both | 300 | Phase 2 | NULL |