46. Malignant rheumatoid arthritis Clinical trials / Disease details

Clinical trials : 4,356 / Drugs : 2,567 - (DrugBank : 415) / Drug target genes : 192 - Drug target pathways : 228

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05756179 (ClinicalTrials.gov)	July 2023	21/2/2023	Effect of Diosmin and Hesperidin in Treatment of Patients With Rheumatoid Arthritis	Clinical Study Evaluating the Effect of Diosmin and Hesperidin in Treatment of Patients With Rheumat ...	Rheumatoid Arthritis	Drug: Diosmin and Hesperidin Combination	Alexandria University	NULL	Not yet recruiting	19 Years	65 Years	All	80	Phase 3	NULL
2	NCT05306353 (ClinicalTrials.gov)	May 15, 2023	23/3/2022	CD40L Antagonism in Rheumatoid Arthritis (RA)	Combining a CD40L-Binding Protein (VIB4920) With a TNF-alpha Inhibitor for the Treatment of Inadequa ...	Rheumatoid Arthritis	Drug: Placebo for VIB4920;Drug: VIB4920 with TNFi;Drug: VIB4920 without TNFi	National Institute of Allergy and Infectious Diseases (NIAID)	Immune Tolerance Network (ITN)	Not yet recruiting	18 Years	70 Years	All	104	Phase 2	United States
3	NCT04585711 (ClinicalTrials.gov)	May 2023	7/10/2020	Pharmacokinetics and Pharmacodynamics of Biologic Drugs in Obese Patients With Arthritis	Pharmacokinetics and Pharmacodynamics of Biologic Drugs in Obese Patients With Arthritis	Juvenile Idiopathic Arthritis;Rheumatoid Arthritis;Obesity	Drug: Etanercept Optimal dosing	Duke University	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	Not yet recruiting	2 Years	65 Years	All	30	Phase 1	United States
4	NCT05622175 (ClinicalTrials.gov)	March 31, 2023	3/11/2022	Safety and Preliminary Signs of Efficacy of F8IL10 for Intra-articular Treatment	A Dose-finding Phase I Study of F8IL10 Intra-articular Treatment in Rheumatoid Arthritis	Rheumatoid Arthritis	Drug: F8IL10	Philogen S.p.A.	NULL	Not yet recruiting	18 Years	80 Years	All	32	Phase 1	NULL
5	NCT02903212 (ClinicalTrials.gov)	March 2023	1/9/2016	Tolerance and Effectiveness of Cell Therapy by Autologous Apoptotic Cells in the Treatment of Rheuma ...	Tolerance and Effectiveness of Cell Therapy by Autologous Apoptotic Cells in the Treatment of Rheuma ...	Arthritis, Rheumatoid	Biological: Autologous apoptotic cells injection	Centre Hospitalier Universitaire de Besancon	NULL	Not yet recruiting	18 Years	80 Years	All	22	Phase 1/Phase 2	NULL
6	NCT05540938 (ClinicalTrials.gov)	February 15, 2023	10/9/2022	Post-marketing Re-evaluation of WangBi Granules for Rheumatoid Arthritis	Reevaluation of Original Research Results of Integrated Traditional Chinese and Western Medicine and ...	Rheumatoid Arthritis	Drug: Wangbi granules;Drug: Wangbi granules simulant	China-Japan Friendship Hospital	Peking Union Medical College Hospital;The First Affiliated Hospital of Anhui University of Tradition ...	Not yet recruiting	18 Years	75 Years	All	340	Phase 4	NULL
7	NCT05725434 (ClinicalTrials.gov)	February 6, 2023	2/2/2023	A Study to Evaluate Usability of Subcutaneous Auto-injector of CT-P47 in Patients With Active Rheuma ...	A Single-arm, Open-label, Multiple-dose, Phase 3 Study to Evaluate Usability of Subcutaneous Auto-in ...	Rheumatoid Arthritis	Biological: CT-P47 AI (tocilizumab);Biological: CT-P47 PFS (tocilizumab)	Celltrion	NULL	Not yet recruiting	18 Years	70 Years	All	30	Phase 3	NULL
8	NCT05305066 (ClinicalTrials.gov)	February 1, 2023	26/2/2022	Stand UP to Rheumatoid Arthritis (SUPRA)	Innovative Trial Designs, Multi-omics and Advanced Computational Prediction to Transform Clinical Ca ...	Rheumatoid Arthritis	Drug: TNFi;Drug: Anti-IL6;Drug: JAKi	Marie Hudson, MD	McGill University Health Centre/Research Institute of the McGill University Health Centre;Montreal G ...	Recruiting	18 Years	N/A	All	75	N/A	Canada
9	NCT05718583 (ClinicalTrials.gov)	February 1, 2023	30/1/2023	Effects of Administration of SCFA in Rheumatoid Arthritis Inadequate Responders	A Pilot Proof of Concept Study of the Effects of Administration of a Short Chain Fatty Acid (SCFA) S ...	Rheumatoid Arthritis	Dietary Supplement: Butyrate	NYU Langone Health	Arthritis Foundation	Recruiting	18 Years	N/A	All	35	N/A	United States
10	NCT03938701 (ClinicalTrials.gov)	January 2023	25/2/2019	Fluorescence Imaging of Disease Activity in IBD and Rheumatoid Arthritis Using OTL38	Fluorescence Imaging for the Evaluation of Disease Activity in IBD and Rheumatoid ArthritisUsing the ...	IBD;Rheumatoid Arthritis	Drug: OTL38;Device: Fluorescence Imaging	University Medical Center Groningen	GlaxoSmithKline;On Target Laboratories, LLC;Amsterdam UMC, location VUmc	Not yet recruiting	18 Years	N/A	All	30	Phase 1	Netherlands

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