46. Malignant rheumatoid arthritis Clinical trials / Disease details

Clinical trials : 4,356 / Drugs : 2,567 - (DrugBank : 415) / Drug target genes : 192 - Drug target pathways : 228

30 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04246762 (ClinicalTrials.gov)	April 6, 2021	27/1/2020	Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Single Dose of Olokizumabon ...	A Phase 1, Open-label, Study in Subjects With Rheumatoid Arthritis to Evaluate the Effect of a Singl ...	Rheumatoid Arthritis	Drug: Olokizumab;Drug: Omeprazole;Drug: Caffeine;Drug: Warfarin + Vitamin K;Drug: Midazolam	R-Pharm International, LLC	IQVIA RDS Ireland Ltd;Thermo Fisher Scientific FS	Completed	18 Years	70 Years	All	16	Phase 1	Bulgaria;Moldova, Republic of
2	EUCTR2015-005309-35-LV (EUCTR)	04/08/2017	19/05/2017	Study of the Efficacy and Safety of Olokizumabin Patients with Moderately to Severely Active Rheumat ...	A Multicenter, Open-Label, Phase III Study of the Efficacy and Safety of Olokizumabin Subjects with ...	Moderately to Severely Active Rheumatoid Arthritis MedDRA version: 20.0;Level: PT;Classification cod ...	Product Name: Olokizumab Product Code: (CDP6038; L04041) INN or Proposed INN: Olokizumab Other descript ...	R-Pharm	NULL	Not Recruiting			Female: yes Male: yes	1880	Phase 3	United States;Belarus;Taiwan;Estonia;Turkey;Lithuania;Russian Federation;Colombia;United Kingdom;Cze ...
3	NCT03120949 (ClinicalTrials.gov)	July 4, 2017	7/2/2017	Efficacy and Safety of Olokizumabin Subjects With Moderately to Severely Active Rheumatoid Arthritis ...	A Multicenter, Open-Label, Phase III Study of the Efficacy and Safety of Olokizumabin Subjects With ...	Rheumatoid Arthritis	Drug: Olokizumab 64 mg SC q4w;Drug: Olokizumab 64 mg SC q2w	R-Pharm International, LLC	IQVIA Pvt. Ltd;OCT Clinical Trials	Completed	18 Years	N/A	All	2106	Phase 3	United States;Argentina;Belarus;Brazil;Bulgaria;Colombia;Czechia;Estonia;Latvia;Lithuania;Mexico;Pol ...
4	EUCTR2015-005309-35-BG (EUCTR)	22/06/2017	02/05/2017	Study of the Efficacy and Safety of Olokizumabin Patients with Moderately to Severely Active Rheumat ...	A Multicenter, Open-Label, Phase III Study of the Efficacy and Safety of Olokizumabin Subjects with ...	Moderately to Severely Active Rheumatoid Arthritis MedDRA version: 23.1;Level: PT;Classification cod ...	Product Name: Olokizumab Product Code: (CDP6038; L04041) INN or Proposed INN: Olokizumab Other descript ...	R-Pharm International, LLC.	NULL	Not Recruiting			Female: yes Male: yes	1880	Phase 3	Belarus;United States;Czechia;Taiwan;Estonia;Lithuania;Turkey;Russian Federation;Colombia;United Kin ...
5	EUCTR2015-005309-35-GB (EUCTR)	16/06/2017	09/06/2016	Study of the Efficacy and Safety of Olokizumabin Patients with Moderately to Severely Active Rheumat ...	A Multicenter, Open-Label, Phase III Study of the Efficacy and Safety of Olokizumabin Subjects with ...	Moderately to Severely Active Rheumatoid Arthritis MedDRA version: 20.0;Level: PT;Classification cod ...	Product Name: Olokizumab Product Code: (CDP6038; L04041) INN or Proposed INN: Olokizumab Other descript ...	R-Pharm	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1880	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United States;Belarus;Taiwan;Estonia;Lithuania;Turkey;Russian Federation;Colombia;United Kingdom;Cze ...
6	EUCTR2015-005309-35-DE (EUCTR)	23/05/2017	24/01/2017	Study of the Efficacy and Safety of Olokizumabin Patients with Moderately to Severely Active Rheumat ...	A Multicenter, Open-Label, Phase III Study of the Efficacy and Safety of Olokizumabin Subjects with ...	Moderately to Severely Active Rheumatoid Arthritis MedDRA version: 23.1;Level: PT;Classification cod ...	Product Name: Olokizumab Product Code: (CDP6038; L04041) INN or Proposed INN: Olokizumab Other descript ...	R-Pharm International LLC	NULL	Not Recruiting			Female: yes Male: yes	1880	Phase 3	United Kingdom;Czech Republic;Hungary;Mexico;Argentina;Poland;Brazil;Romania;Bulgaria;Germany;Latvia ...
7	EUCTR2015-005309-35-PL (EUCTR)	19/05/2017	17/03/2017	Study of the Efficacy and Safety of Olokizumabin Patients with Moderately to Severely Active Rheumat ...	A Multicenter, Open-Label, Phase III Study of the Efficacy and Safety of Olokizumabin Subjects with ...	Moderately to Severely Active Rheumatoid Arthritis MedDRA version: 23.1;Level: PT;Classification cod ...	Product Name: Olokizumab Product Code: (CDP6038; L04041) INN or Proposed INN: Olokizumab Other descript ...	R-Pharm International LLC	NULL	Not Recruiting			Female: yes Male: yes	1880	Phase 3	Belarus;United States;Czechia;Estonia;Taiwan;Lithuania;Turkey;Russian Federation;Colombia;United Kin ...
8	EUCTR2015-005307-83-RO (EUCTR)	28/03/2017	22/06/2016	Study of the Efficacy and Safety of Olokizumabin Patients with Moderately to Severely Active Rheumat ...	A Randomized, Double-Blind, Parallel-Group, Placebo- and Active-Controlled, Multicenter Phase III St ...	Moderately to Severely Active Rheumatoid Arthritis MedDRA version: 23.1;Level: PT;Classification cod ...	Product Name: Olokizumab Product Code: (CDP6038; L04041) INN or Proposed INN: Olokizumab Other descript ...	R-Pharm	NULL	Not Recruiting			Female: yes Male: yes	1575	Phase 3	United States;Czechia;Taiwan;Estonia;Lithuania;Russian Federation;Colombia;United Kingdom;Czech Repu ...
9	EUCTR2015-005309-35-CZ (EUCTR)	16/03/2017	31/01/2017	Study of the Efficacy and Safety of Olokizumabin Patients with Moderately to Severely Active Rheumat ...	A Multicenter, Open-Label, Phase III Study of the Efficacy and Safety of Olokizumabin Subjects with ...	Moderately to Severely Active Rheumatoid Arthritis MedDRA version: 20.0;Level: PT;Classification cod ...	Product Name: Olokizumab Product Code: (CDP6038; L04041) INN or Proposed INN: Olokizumab Other descript ...	R-Pharm International LLC	NULL	Not Recruiting			Female: yes Male: yes	1880	Phase 3	United States;Belarus;Taiwan;Estonia;Turkey;Lithuania;Russian Federation;Colombia;United Kingdom;Cze ...
10	EUCTR2015-005309-35-HU (EUCTR)	16/03/2017	02/02/2017	Study of the Efficacy and Safety of Olokizumabin Patients with Moderately to Severely Active Rheumat ...	A Multicenter, Open-Label, Phase III Study of the Efficacy and Safety of Olokizumabin Subjects with ...	Moderately to Severely Active Rheumatoid Arthritis MedDRA version: 19.1;Level: PT;Classification cod ...	Product Name: Olokizumab Product Code: (CDP6038; L04041) INN or Proposed INN: Olokizumab Other descript ...	R-Pharm	NULL	Not Recruiting			Female: yes Male: yes	1880	Phase 3	United States;Belarus;Taiwan;Estonia;Turkey;Lithuania;Russian Federation;Colombia;United Kingdom;Hun ...

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