46. Malignant rheumatoid arthritis Clinical trials / Disease details

Clinical trials : 4,356 / Drugs : 2,567 - (DrugBank : 415) / Drug target genes : 192 - Drug target pathways : 228

13 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04170426 (ClinicalTrials.gov)	December 2022	18/11/2019	Autologous Adipose-derived Stem Cells (AdMSCs) for Rheumatoid Arthritis	Phase 1/2a Clinical Study for Subjects With Rheumatoid Arthritis (RA) Using Multiple Dose Intravenou ...	Rheumatoid Arthritis	Biological: autologous adipose derived stem cells	Celltex Therapeutics Corporation	NULL	Not yet recruiting	18 Years	75 Years	All	54	Phase 1/Phase 2	NULL
2	NCT05379322 (ClinicalTrials.gov)	July 2022	12/5/2022	The Use of Synovial Biopsies in Predicting Response to Biologic Therapy in Rheumatoid Arthritis Pati ...	The Use of Synovial Biopsies in Predicting Response to Biologic Therapy in Rheumatoid Arthritis Pati ...	Rheumatoid Arthritis	Drug: Anti-TNF;Drug: JAK inhibitor	Abu Dhabi Stem Cells Center	NULL	Withdrawn	18 Years	N/A	All	0	Phase 3	United Arab Emirates
3	ChiCTR1800018338	2019-01-01	2018-09-12	A Clinical Trial for Human Gingiva Mesenchymal Stem Cells in the Treatment of Rheumatoid Arthritis	A Clinical Trial for Human Gingiva Mesenchymal Stem Cells in the Treatment of Rheumatoid Arthritis	Rheumatoid Arthritis	Control:Normal Saline iv. besides MTX treatment;Treatment:GMSC iv. besides MTX treatment;	theThird Affiliated Hospital of Sun Yat-sen University	NULL	Pending	18	65	Both	Control:123;Treatment:123;	I (Phase 1 study)	China
4	NCT03691909 (ClinicalTrials.gov)	September 25, 2018	27/9/2018	Phase 1/2a Clinical Trial to Assess the Safety of HB-adMSCs for the Treatment of Rheumatoid Arthriti ...	A Phase 1/2a Clinical Trial to Assess Safety of a Single IV Infusion of Autologous Adipose-derived M ...	Rheumatoid Arthritis	Biological: HB-adMSCs	Hope Biosciences	NULL	Completed	18 Years	65 Years	All	15	Phase 1/Phase 2	United States
5	NCT03798028 (ClinicalTrials.gov)	December 26, 2017	7/1/2019	The Safety and Effects of Mesenchymal Stem Cell (MSCs) in the Treatment of Rheumatoid Arthritis	The Effects and Safety of Mesenchymal Stem Cellsin the Treatment of Moderate/Severe Rheumatoid Arthr ...	Rheumatoid Arthritis	Biological: UC-MSCs	Xijing Hospital	Changhai Hospital;Southwest Hospital, China	Unknown status	18 Years	70 Years	All	250	N/A	China
6	NCT03186417 (ClinicalTrials.gov)	December 15, 2017	12/6/2017	Mesenchymal Stem Cells in Early Rheumatoid Arthritis	Cell-Based Therapy in Rheumatoid Arthritis: Proof of Concept Phase 1 Trial	Rheumatoid Arthritis	Biological: 2 million hMSC/kg;Biological: 4 million hMSC/kg;Biological: 6 million hMSC/kg;Biological ...	MetroHealth Medical Center	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	Recruiting	18 Years	80 Years	All	20	Phase 1	United States
7	NCT03067870 (ClinicalTrials.gov)	November 2016	25/2/2017	Transplantation of Autologous Bone Marrow Derived Stem Cells in Patients With Rheumatoid Arthritis	Transplantation of Autologous Purified Bone Marrow Derived Specific Populations of Stem Cellsand Mes ...	RheumatoId Arthritis;Osteoarthritis, Knee;Osteoarthritis, Hip	Biological: Stem Cell Transplantation	Stem Cells Arabia	NULL	Active, not recruiting	17 Years	75 Years	All	100	Phase 1	NULL
8	NCT03333681 (ClinicalTrials.gov)	June 20, 2016	14/9/2017	Evaluation of Stem Cell Therapy Effects on the Immune Response in Rheumatoid Arthritis Patients	Evaluation of Mesenchymal Stem Cell Therapy Effects on the Cellular and Humoral Immune Responses and ...	Rheumatoid Arthritis	Biological: Autologous mesenchymal stem cells	Mashhad University of Medical Sciences	NULL	Completed	35 Years	60 Years	Female	15	Phase 1	NULL
9	NCT02643823 (ClinicalTrials.gov)	January 2016	23/12/2015	Human Umbilical Cord-Mesenchymal Stem Cells for Rheumatoid Arthritis	Safety and Efficacy Study of Human Umbilical Cord-Mesenchymal Stem Cells for Rheumatoid Arthritis	Rheumatoid Arthritis	Biological: hUC-MSC + DMARDs;Drug: DMARDs	Shenzhen Hornetcorn Bio-technology Company, LTD	Futian People's Hospital	Recruiting	18 Years	80 Years	Both	40	Phase 1	China
10	NCT01985464 (ClinicalTrials.gov)	October 2013	31/10/2013	Umbilical Cord Tissue-derived Mesenchymal Stem Cells for Rheumatoid Arthritis	Feasibility Study of Umbilical Cord Tissue Derived Mesenchymal Stem Cells(UC-MSC) in Disease Modifyi ...	Rheumatoid Arthritis	Biological: Umbilical cord mesenchymal stem cells	Translational Biosciences	NULL	Unknown status	18 Years	N/A	All	20	Phase 1/Phase 2	Panama

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