49. Systemic lupus erythematosus Clinical trials / Disease details
Clinical trials : 993 / Drugs : 702 - (DrugBank : 184) / Drug target genes : 116 - Drug target pathways : 200
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT05000216 (ClinicalTrials.gov) | August 13, 2021 | 6/8/2021 | COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders | Booster Effects With Autoimmune Treatments in Patients With Poor Response to Initial COVID-19 Vaccine (ACV01) | Rheumatoid Arthritis (RA);Systemic Lupus Erythematosus (SLE);Pemphigus Vulgaris;Multiple Sclerosis (MS);Systemic Sclerosis (SSc);Pediatric SLE;Juvenile Idiopathic Arthritis (JIA);Juvenile Dermatomyositis (JDM);Pediatric-Onset Multiple Sclerosis (POMS) | Biological: Moderna mRNA-1273;Biological: BNT162b2;Biological: Ad26.COV2.S;Drug: Continue IS (MMF or MPA);Drug: Continue IS (MTX);Biological: Continue IS (B cell depletion therapy);Biological: Monovalent [B.1.351] CoV2 preS dTM-AS03;Drug: Withhold IS (MMF or MPA);Drug: Withhold IS (MTX);Drug: Withhold IS (B cell depletion therapy);Biological: Moderna mRNA-1273, Bivalent;Biological: BNT162b2, Bivalent | National Institute of Allergy and Infectious Diseases (NIAID) | Autoimmunity Centers of Excellence;Rho Federal Systems Division, Inc. | Recruiting | 2 Years | N/A | All | 2340 | Phase 2 | United States |
| 2 | ChiCTR2000030247 | 2020-03-01 | 2020-02-26 | Clinical study of guanxining tablet in the treatment of rheumatoid arthritis with cardiovascular damage | Clinical study of guanxining tablet in the treatment of rheumatoid arthritis with cardiovascular damage | Systemic lupus erythematosus | experimental group:Integrative MTX with Guanxinning;control group:MTX; | Zhejinag University of f Chinese Medicine | NULL | Recruiting | Both | experimental group:30;control group:30; | China | |||
| 3 | ITMCTR2000003055 | 2020-03-01 | 2020-02-26 | Clinical study of guanxining tablet in the treatment of rheumatoid arthritis with cardiovascular damage | Clinical study of guanxining tablet in the treatment of rheumatoid arthritis with cardiovascular damage | Systemic lupus erythematosus | experimental group:Integrative MTX with Guanxinning;control group:MTX; | Zhejinag University of f Chinese Medicine | NULL | Recruiting | Both | experimental group:30;control group:30; | China |