49. Systemic lupus erythematosus Clinical trials / Disease details

Clinical trials : 993 / Drugs : 702 - (DrugBank : 184) / Drug target genes : 116 - Drug target pathways : 200

22 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05666336 (ClinicalTrials.gov)	December 31, 2022	8/12/2022	Multi-omics Studies on the Efficacy of Telitacicept in Chinese SLE Patients	Proteomics Combined With Metabolomics Studies on the Efficacy of Telitacicept in Chinese Patients of ...	Systemic Lupus Erythematosus	Biological: Telitacicept;Drug: Hydroxychloroquine;Drug: Prednisone;Drug: Methylprednisolone;Drug: Cy ...	Fen Li	NULL	Not yet recruiting	18 Years	75 Years	All	30	Phase 4	NULL
2	NCT05306873 (ClinicalTrials.gov)	October 28, 2022	11/3/2022	Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus	A Phase 2, Double-Blind, Placebo-Controlled Trial of Mycophenolate MofetilAlone or With Voclosporin ...	Systemic Lupus Erythematosus	Drug: Mycophenolate Mofetil;Drug: Placebo for Mycophenolate Mofetil;Drug: Voclosporin;Drug: Placebo fo ...	National Institute of Allergy and Infectious Diseases (NIAID)	NULL	Recruiting	18 Years	60 Years	All	120	Phase 2	United States
3	NCT04702256 (ClinicalTrials.gov)	December 9, 2021	30/11/2020	Induction Therapy for Lupus Nephritis With no Added Oral Steroids: A Trial Comparing Oral Corticoste ...	Induction Therapy for Lupus Nephritis With no Added Oral Steroids: An Open Label Randomised Multicen ...	Lupus Nephritis;Systemic Lupus Erythematosus (SLE)	Drug: Obinutuzumab administration;Drug: Administration of Methylprednisolone + Prednisone + Mycopheno ...	Assistance Publique - Hôpitaux de Paris	Roche Pharma AG	Recruiting	14 Years	N/A	All	196	Phase 3	France
4	NCT05057481 (ClinicalTrials.gov)	September 15, 2021	16/9/2021	Reappraisal of the Therapies of Refractory Autoimmune Hemolytic Anemia in Systemic Lupus Erythematos ...	Reappraisal of Second-line Therapies of Refractory Autoimmune Hemolytic Anemia in Systemic Lupus Ery ...	Autoimmune Hemolytic Anemia;Systemic Lupus Erythematosus	Drug: Mycophenolate Mofetil 500mg;Drug: Rituximab	Assiut University	NULL	Active, not recruiting	18 Years	N/A	All	30	Phase 3	Egypt
5	ChiCTR1800017540	2018-09-01	2018-08-03	A randomized controlled trial for the long-term outcomes of MMF on new onset SLE patients with high ...	A randomized controlled trial for the long-term outcomes of MMF on new onset SLE patients with high ...	systemic lupus erythematosus	1:Hydroxychloroquine(5mg/kg/day) plus prednisone(0.5mg/kg/day);2:Hydroxychloroquine(5mg/kg/day) plus ...	Ruijin Hospital	NULL	Completed	18	65	Both	1:65;2:65;	Phase 4	China
6	NCT03492255 (ClinicalTrials.gov)	April 12, 2018	16/3/2018	CYCLONES - CYClophosphamide LOw Dose and No Extra Steroid	CYCLONES - CYClophosphamide LOw Dose and No Extra Steroid	Systemic Lupus Erythematosus (SLE)	Drug: Cyclophosphamide;Drug: Methylprednisolone;Drug: Prednisone;Drug: Mycophenolate Mofetil	University of Sao Paulo General Hospital	Fundação de Amparo à Pesquisa do Estado de São Paulo	Terminated	18 Years	N/A	All	49	N/A	Brazil
7	NCT02080195 (ClinicalTrials.gov)	September 13, 2016	28/2/2014	Nonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythe ...	A Phase I/II Study of Nonmyeloablative Conditioning and Transplantation of Human Leukocyte Antigen ( ...	Lupus Erythematosus;Graft-versus-host Disease	Drug: Cyclophosphamide;Drug: Fludarabine;Drug: Tacrolimus;Drug: Mycophenolate Mofetil;Drug: Rabbit ant ...	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Maryland Stem Cell Research Fund	Terminated	18 Years	75 Years	All	1	Phase 1/Phase 2	United States
8	JPRN-UMIN000025328	2015/12/05	25/12/2016	A Randomized Open-label Study to Evaluate the Efficacy and Safety of Tacrolimus and Corticosteroids ...	A Randomized Open-label Study to Evaluate the Efficacy and Safety of Tacrolimus and Corticosteroids ...	systemic lupus erythematosus	Tacrolimus Mycophenolate Mofetil	The University of Hong Kong	NULL	Recruiting	18years-old	75years-old	Male and Female	200	Not selected	Japan,Asia(except Japan)
9	NCT01773616 (ClinicalTrials.gov)	April 2015	1/11/2012	Trial of Rituximab and Mycophenolate Mofetil Without Oral Steroids for Lupus Nephritis	Phase 3 Open Label Randomised Multicentre Controlled Trial of Rituxmab and Mycophenolate MofetilWith ...	Systemic Lupus Erythematosus, Lupus Nephritis	Drug: Oral prednisolone;Drug: Rituximab;Drug: Mycophenolate mofetil;Drug: Methyl prednisolone	Imperial College London	Karolinska Institutet;Ohio State University;Dutch Working Party on Systemic Lupus Erythematosus;EULA ...	Terminated	12 Years	75 Years	All	24	Phase 3	United Kingdom
10	NCT01946880 (ClinicalTrials.gov)	November 20, 2013	13/9/2013	Randomized MMF Withdrawal in Systemic Lupus Erythematosus (SLE)	An Investigator-Initiated, Phase II, Randomized, Withdrawal Study of Mycophenolate Mofetil(MMF) in P ...	Systemic Lupus Erythematosus;SLE	Drug: Mycophenolate Mofetil;Drug: Hydroxychloroquine or Chloroquine;Drug: Prednisone	National Institute of Allergy and Infectious Diseases (NIAID)	Autoimmunity Centers of Excellence;Rho Federal Systems Division, Inc.	Terminated	18 Years	70 Years	All	102	Phase 2	United States

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