51. Scleroderma Clinical trials / Disease details

Clinical trials : 525 / Drugs : 565 - (DrugBank : 148) / Drug target genes : 114 - Drug target pathways : 217

14 trials found

diseases per page:

Showing 1 to 10 of 14 diseases

Filter by

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01309997 (ClinicalTrials.gov)	March 2011	1/3/2011	Imatiniband Rituximab in Treating Cutaneous Sclerosis in Patients With Chronic Graft-Versus-Host Dis ...	A Randomized Phase II Study of Imatiniband Rituximab for Cutaneous Sclerosis After Allogeneic Hemato ...	Graft Versus Host Disease;Systemic Scleroderma	Drug: imatinib mesylate;Biological: rituximab	Lee, Stephanie	National Cancer Institute (NCI)	Completed	2 Years	N/A	All	72	Phase 2	United States
2	NCT00573326 (ClinicalTrials.gov)	February 2009	13/12/2007	Low-Dose Oral Imatinib for Scleroderma Pulmonary Involvement	Low-Dose Oral Imatinib in the Treatment of Scleroderma Pulmonary Involvement: A Phase II Pilot Study	Systemic Sclerosis	Drug: Imatinib	Azienda Ospedaliera Universitaria Policlinico	Università Politecnica delle Marche	Recruiting	18 Years	80 Years	Both	30	Phase 2	Italy
3	EUCTR2007-004669-17-IT (EUCTR)	17/12/2008	16/06/2008	A multi-centre, open-label, Proof of Concept (PoC) study to evaluate the efficacy and tolerability o ...	A multi-centre, open-label, Proof of Concept (PoC) study to evaluate the efficacy and tolerability o ...	sistemic sclerosis MedDRA version: 9.1;Level: LLT;Classification code 10018124;Term: Generalized scl ...	Trade Name: GLIVEC INN or Proposed INN: IMATINIB MESILATO	NOVARTIS FARMA	NULL	Not Recruiting			Female: yes Male: yes	27		United Kingdom;Italy
4	EUCTR2007-004669-17-DE (EUCTR)	10/07/2008	13/03/2008	A multi-centre, open-label, Proof of Concept (PoC) study to evaluate the efficacy and tolerability o ...	A multi-centre, open-label, Proof of Concept (PoC) study to evaluate the efficacy and tolerability o ...	systemic sclerosis MedDRA version: 9.1;Level: LLT;Classification code 10042953;Term: Systemic sclero ...	Trade Name: Glivec 100 mg Filmtabletten Product Name: Glivec Product Code: STI571 INN or Proposed INN: i ...	Novartis Pharma Services AG	NULL	Not Recruiting			Female: yes Male: yes	27		Germany;Italy;United Kingdom
5	NCT01545427 (ClinicalTrials.gov)	April 2008	1/3/2012	Proof of Concept Trial of Gleevec (Imatinib) in Active Diffuse Scleroderma	A Proof of Concept Trial of Gleevec (Imatinib) in Active Diffuse Scleroderma	Scleroderma	Drug: Imatinib mesylate;Other: Placebo	Lawson Health Research Institute	Novartis Pharmaceuticals	Terminated	18 Years	N/A	Both	10	Phase 2	Canada
6	EUCTR2007-004669-17-GB (EUCTR)	15/02/2008	16/10/2007	A multi-center, open-label, Proof of Concept (PoC) study to evaluate the efficacy and tolerability o ...	A multi-center, open-label, Proof of Concept (PoC) study to evaluate the efficacy and tolerability o ...	Skin fibrosis in systemic sclerosis patients MedDRA version: 9.1;Level: LLT;Classification code 1004 ...	Trade Name: Glivec Product Name: Glivec Product Code: STI571 INN or Proposed INN: imatinib	Novartis Pharma Services AG	NULL	Not Recruiting			Female: yes Male: yes	27		United Kingdom;Italy
7	NCT00613171 (ClinicalTrials.gov)	January 2, 2008	25/1/2008	Efficacy and Tolerability of STI571 (ImatinibMesylate) for the Treatment of Fibrosis in Participants ...	A Multi-centre, Open-label, Proof of Concept (PoC) Study to Evaluate the Efficacy and Tolerability o ...	Systemic Sclerosis, Scleroderma	Drug: STI571	Novartis Pharmaceuticals	NULL	Completed	18 Years	N/A	All	27	Phase 2	United States;Germany;Italy;Switzerland;United Kingdom
8	NCT00479934 (ClinicalTrials.gov)	December 2007	29/5/2007	Efficacy and Safety of Imatinib in Scleroderma	Phase II Randomized Double Blind Clinical Trial of'ImatinibMesylate STI571 (Glivec®) Versus Placebo ...	Scleroderma, Localized;Scleroderma, Systemic	Drug: imatinib mesylate	University Hospital, Bordeaux	Ministry of Health, France;Novartis	Completed	18 Years	N/A	Both	28	Phase 2	France
9	EUCTR2007-005322-68-IT (EUCTR)	30/10/2007	04/10/2007	Low-dose oral imatinibin the treatment of scleroderma pulmonary involvement: a phase II pilot study ...	Low-dose oral imatinibin the treatment of scleroderma pulmonary involvement: a phase II pilot study ...	Systemic Sclerosis MedDRA version: 6.1;Level: PT;Classification code 10042953	Trade Name: GLIVEC INN or Proposed INN: Imatinib	AZIENDA OSPEDALIERO UNIVERSITARIA OSPEDALI RIUNITI UMBERTO I - G.M.LANCISI - G.SALESI	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes		Phase 2	Italy
10	EUCTR2007-001508-19-IT (EUCTR)	06/09/2007	29/07/2008	TRATTAMENTO CON IMATINIBMESILATO DELLA GVH CRONICA SEVERA SCLERODERMA-LIKE REFRATTARIA ALLA TERAPIA ...	TRATTAMENTO CON IMATINIBMESILATO DELLA GVH CRONICA SEVERA SCLERODERMA-LIKE REFRATTARIA ALLA TERAPIA ...	GVH CRONICA ESTESA MedDRA version: 9.1;Level: LLT;Classification code 10018651;Term: Graft versus ho ...	Trade Name: GLIVEC INN or Proposed INN: Imatinib	AZIENDA OSPEDALIERA S. CARLO	NULL	Not Recruiting			Female: yes Male: yes			Italy

First Previous1 2Next Last