57. Idiopathic dilated cardiomyopathy Clinical trials / Disease details


Clinical trials : 11 Drugs : 23 - (DrugBank : 12) / Drug target genes : 9 - Drug target pathways : 35

  
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1NCT02987322
(ClinicalTrials.gov)
November 201529/11/2016Honey in Idiopathic Dilated CardiomyopathyHoney Supplementation in Children With Idiopathic Dilated Cardiomyopathy: A Randomized Controlled StudyIdiopathic Dilated CardiomyopathyDietary Supplement: honeymamdouh abdulmaksoud abdulrhmanNULLCompleted2 Years12 YearsBoth50Phase 2/Phase 3NULL
2NCT02033278
(ClinicalTrials.gov)
January 6, 20149/1/2014Infusion Intracoronary of Mononuclear Autologous Adult no Expanded Stem Cells of Bone Marrow on Functional Recovery in Patients With Idiopathic Dilated Cardiomyopathy and Heart Failure.Multicenter Phase IIb Clinical Trial, Double-blind, Randomized, Controlled Placebo for to Assess the Efficacy of Intracoronary Infusion of Autologous Adult Stem Cells Mononuclear Marrow Unexpanded on Functional Recovery in Patients With Idiopathic Dilated Cardiomyopathy and Heart Failure.Idiopathic Dilated CardiomyopathyDrug: Infusion of autologous mononuclear bone marrow cells;Drug: Placebo infusionAndalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y SaludIniciativa Andaluza en Terapias AvanzadasTerminated18 Years70 YearsAll27Phase 2Spain
3NCT02256501
(ClinicalTrials.gov)
June 20131/10/2014Intracoronary Transplantation of Bone Marrow Derived Mononuclear Cells in Pediatric CardiomyopathyIntracoronary Transplantation of Autologous Bone Marrow Derived Mononuclear Cells (MNC) in Idiopathic Dilated Cardiomyopathy in Pediatric Patients: Clinical Trial Phase I/IICardiomyopathyBiological: Mono Nuclear Cell (MNC) transplantationNasser Aghdami MD., PhDNULLCompleted1 Year16 YearsAll30Phase 1/Phase 2Iran, Islamic Republic of
4NCT02292043
(ClinicalTrials.gov)
May 201331/10/2014Effects of HTEA ON Heart Failure Secondary to Idiopathic Dilated Cardiomyopathy or Post-myocardial InfarctionEffects of HTEA ON Heart Failure Secondary to Idiopathic Dilated Cardiomyopathy or Post-myocardial InfarctionCongestive Heart FailureDrug: HTEAHarbin Medical UniversityNULLRecruiting20 Years80 YearsBoth60N/AChina
5NCT01219452
(ClinicalTrials.gov)
October 201012/10/2010Intramuscular Injection of Mesenchymal Stem Cell for Treatment of Children With Idiopathic Dilated CardiomyopathyEffects of Intramuscular Injection of Umbilical Cord Mesenchymal Stem Cell on the Ventricular Function of Children With Idiopathic Dilated CardiomyopathyDilated CardiomyopathyBiological: umbilical cord mesenchymal stem cellsQingdao UniversityNULLNot yet recruiting1 Year14 YearsBoth30Phase 1/Phase 2China
6NCT01302171
(ClinicalTrials.gov)
August 201021/2/2011Bone Marrow Derived Adult Stem Cells for Dilated CardiomyopathyRandomised Controlled Trial to Compare the Effects of G-CSF (Granocyte™) and Autologous Bone Marrow Progenitor Cells on Quality of Life and Left Ventricular Function in Patients With Idiopathic Dilated CardiomyopathyDilated CardiomyopathyDrug: granulocyte colony stimulating factor (GCSF);Procedure: bone marrow mononuclear cellsBarts & The London NHS TrustRoyal Brompton & Harefield NHS Foundation Trust;University College London HospitalsCompleted18 Years80 YearsBoth60Phase 2United Kingdom
7EUCTR2009-013112-12-GB
(EUCTR)
22/04/201017/03/2010Randomised Controlled Trial To Compare The effects of G-CSF(Granocyte™) And Autologous Bone Marrow Progenitor Cells On Quality Of Life And Left Ventricular Function In Patients with Idiopathic Dilated Cardiomyopathy - REGENERATE-DCMRandomised Controlled Trial To Compare The effects of G-CSF(Granocyte™) And Autologous Bone Marrow Progenitor Cells On Quality Of Life And Left Ventricular Function In Patients with Idiopathic Dilated Cardiomyopathy - REGENERATE-DCM Idiopathic Dilated Cardiomyopathy
Level: LLTClassification code 10056419Term: Dilated Cardiomyopathy
Trade Name: Granocyte Lenograstim
Product Name: GRANOCYTE - 34 million IU (Lenograstim rHuG-CSF)
Product Code: PL 12185/0002 & PL 12185/0005(WATER FOR INJECTION)
Barts & the London NHS TrustNULLNot RecruitingFemale: yes
Male: yes
United Kingdom
8NCT02115581
(ClinicalTrials.gov)
September 200622/12/2008Coenzyme Q10 Supplementation in Children With Idiopathic Dilated CardiomyopathyEffect of Coenzyme Q10 (Ubiquinone) Supplementation on Ventricular Function of Children With Idiopathic Dilated Cardiomyopathy.A Randomised Clinical TrialDilated CardiomyopathyDrug: Coenzyme Q10;Drug: PlaceboUniversity of TehranNULLCompleted6 Months18 YearsAll38Phase 4Iran, Islamic Republic of
9NCT01917149
(ClinicalTrials.gov)
March 200530/7/2013Supramaximal Titrated Inhibition of RAAS in Dilated CardiomyopathyEfficacy and Safety Study of Supramaximal Titrated Inhibition of RAAS in Idiopathic Dilated CardiomyopathyDilated CardiomyopathyDrug: Benazepril;Drug: Valsartan;Drug: MetoprololXijing HospitalNULLCompleted18 Years70 YearsBoth480Phase 4China
10NCT00281255
(ClinicalTrials.gov)
June 200320/1/2006Intravenous Allopurinol to Improve Heart Function in Individuals With Dilated CardiomyopathyAllopurinol and Cardiac Function Pilot Study in Idiopathic Dilated CardiomyopathyCardiovascular Diseases;Cardiomyopathy, Dilated;Heart Diseases;Heart Failure, CongestiveDrug: Allopurinol;Drug: DobutamineUniversity of PennsylvaniaNational Heart, Lung, and Blood Institute (NHLBI)Withdrawn18 YearsN/ABoth0Phase 1/Phase 2United States
11NCT01798992
(ClinicalTrials.gov)
September 200022/2/2013Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human HeartBeta-blocker Effect on Structural Remodeling and Gene Expression in the Failing Human HeartIdiopathic Dilated CardiomyopathyDrug: Carvedilol;Drug: Metoprolol succinate;Drug: Metoprolol succinate + doxazosinUniversity of Colorado, DenverNational Heart, Lung, and Blood Institute (NHLBI);GlaxoSmithKline;AstraZenecaCompleted18 YearsN/AAll56Phase 4United States