6. Parkinson disease Clinical trials / Disease details

Clinical trials : 2,307 / Drugs : 2,007 - (DrugBank : 349) / Drug target genes : 188 - Drug target pathways : 199

22 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05709301 (ClinicalTrials.gov)	April 1, 2023	11/1/2023	Randomized Clinical Trial of Donepezilfor the Treatment of Mild Cognitive Impairment in Parkinson's ...	Multicenter, Randomized, Double-blinded, Placebo-controlled Clinical Trial of Donepezilfor the Treat ...	Parkinson Disease;Mild Cognitive Impairment	Drug: Donepezil Hydrochloride;Drug: Placebo	Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau	NULL	Not yet recruiting	50 Years	80 Years	All	120	Phase 2	NULL
2	NCT04117178 (ClinicalTrials.gov)	February 4, 2020	30/9/2019	Monitoring Anti-Dementia Drugs by Serum Levels	Monitoring Anti-Dementia Drugs by Serum Levels: Importance of Serum Levels, Drug-monitoring, Side-ef ...	Dementia;Dementia With Lewy Bodies;Dementia in Parkinsons Disease;Dementia Alzheimers;Alzheimer Dise ...	Drug: Donepezil;Drug: Memantine;Diagnostic Test: Measurement of serum level of anti-dementia drug	Zealand University Hospital	Epilepsihospitalet Filadelfia	Recruiting	18 Years	N/A	All	110	Phase 4	Denmark
3	NCT03599726 (ClinicalTrials.gov)	July 30, 2018	29/6/2018	Improving Walking Automaticity in Parkinson's Disease: Levodopa or Donepezil	Improving Walking Automaticity in Parkinson's Disease: Levodopa or Donepezil	Parkinson Disease	Drug: Donepezil;Drug: Placebo	Oregon Health and Science University	Medical Research Foundation, Oregon	Completed	50 Years	90 Years	All	20	Early Phase 1	United States
4	EUCTR2017-002707-10-DK (EUCTR)	10/04/2018	03/11/2017	Measurements of drug concentration in the blood for anti-dementia drugs, in order to improve efficac ...	Serum-monitoring of anti-dementia drugs, and the relevance to side-effects, clinical efficacy and co ...	Dementia in Alzheimers Disease, Parkinsons Disease and Dementia with Lewy Bodies MedDRA version: 20. ...	Trade Name: Memantin Orion INN or Proposed INN: MEMANTINE Product Name: Donepezil Sandoz Product Code: 2 ...	Regional Dementia Research Centre, Dept of Neurology	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	110	Phase 4	Denmark
5	NCT03011476 (ClinicalTrials.gov)	April 11, 2017	27/12/2016	Effect of Acetylcholinesterase Inhibitors on the Gait of the Patients With Parkinson Disease	Effect of Acetylcholinesterase Inhibitors on the Gait of the Patients With Parkinson Disease Charact ...	Parkinson Disease	Drug: Donepezil;Drug: Placebos	Kyung Hee University Hospital	NULL	Unknown status	40 Years	75 Years	All	20	Phase 4	Korea, Republic of
6	NCT02857244 (ClinicalTrials.gov)	November 2016	25/7/2016	A Multidisciplinary Approach to Manage Gait Difficulty in Parkinson Patients	A Multidisciplinary Approach to Manage Gait Difficulty in Parkinson Patients	Parkinson's Disease	Drug: Duloxetine;Drug: Donepezil;Drug: Modafinil	University of Chicago	NULL	Withdrawn	18 Years	100 Years	All	0	Phase 2	United States
7	NCT02415062 (ClinicalTrials.gov)	July 2015	14/3/2015	The Efficacy and Safety Study of High Dose Donepezil in Parkinson's Disease With Dementia	The Efficacy of 23mg Versus 10mg of Donepezil in ParkInson's Disease With Dementia	Parkinson's Disease	Drug: Donepezil	Inje University	NULL	Recruiting	50 Years	80 Years	Both	150	Phase 2	Korea, Republic of
8	NCT02450786 (ClinicalTrials.gov)	June 2015	14/5/2015	Effect of Donepezil on Cognition in Parkinson's Disease With Mild Cognitive Impairment (PD-MCI)		Parkinson's Disease	Drug: Donepezil	Yonsei University	NULL	Active, not recruiting	40 Years	N/A	All	80	Phase 2	Korea, Republic of
9	NCT02206620 (ClinicalTrials.gov)	July 2014	29/7/2014	Effects of Cholinergic Augmentation on Measures of Balance and Gait	Effects of Cholinergic Augmentation on Measures of Balance and Gait	Parkinson's Disease	Drug: Donepezil	Oregon Health and Science University	Michael J. Fox Foundation for Parkinson's Research	Completed	30 Years	N/A	All	49	Phase 2	United States
10	JPRN-UMIN000010752	2013/05/17	17/05/2013	A study on usefulness and safety of donepezilfor cognitive function and phychological symptoms of pa ...	A study on usefulness and safety of donepezilfor cognitive function and phychological symptoms of pa ...	Parkinson's disease	donepezil	Kansai Medical University	NULL	Complete: follow-up complete	Not applicable	Not applicable	Male and Female	50	Not selected	Japan

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