6. Parkinson disease Clinical trials / Disease details

Clinical trials : 2,307 / Drugs : 2,007 - (DrugBank : 349) / Drug target genes : 188 - Drug target pathways : 199

18 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04117178 (ClinicalTrials.gov)	February 4, 2020	30/9/2019	Monitoring Anti-Dementia Drugs by Serum Levels	Monitoring Anti-Dementia Drugs by Serum Levels: Importance of Serum Levels, Drug-monitoring, Side-ef ...	Dementia;Dementia With Lewy Bodies;Dementia in Parkinsons Disease;Dementia Alzheimers;Alzheimer Dise ...	Drug: Donepezil;Drug: Memantine;Diagnostic Test: Measurement of serum level of anti-dementia drug	Zealand University Hospital	Epilepsihospitalet Filadelfia	Recruiting	18 Years	N/A	All	110	Phase 4	Denmark
2	NCT03858270 (ClinicalTrials.gov)	April 1, 2019	2/10/2018	Inhibition of a-synuclein Cell-cell Transmission by NMDAR Blocker, Memantine	Inhibition of a-synuclein Cell-cell Transmission by NMDAR Blocker, Memantine	Parkinson Disease	Drug: Memantine;Other: Placebo	Wayne State University	NULL	Recruiting	45 Years	85 Years	All	50	Phase 3	United States
3	EUCTR2017-002707-10-DK (EUCTR)	10/04/2018	03/11/2017	Measurements of drug concentration in the blood for anti-dementia drugs, in order to improve efficac ...	Serum-monitoring of anti-dementia drugs, and the relevance to side-effects, clinical efficacy and co ...	Dementia in Alzheimers Disease, Parkinsons Disease and Dementia with Lewy Bodies MedDRA version: 20. ...	Trade Name: Memantin Orion INN or Proposed INN: MEMANTINE Product Name: Donepezil Sandoz Product Code: 2 ...	Regional Dementia Research Centre, Dept of Neurology	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	110	Phase 4	Denmark
4	JPRN-UMIN000010596	2013/05/01	01/05/2013	Randomized crossover trial comparing memantineor amantadine for Parkinson's disease with motor fluct ...	Randomized crossover trial comparing memantineor amantadine for Parkinson's disease with motor fluct ...	Parkinson's disease	Memantinepreceding arm Titrate the memantine, administered for 3 months. And tapering memantineand am ...	Department of Neurology, Juntendo University School of Medicine	NULL	Complete: follow-up complete	20years-old	Not applicable	Male	40	Not selected	Japan
5	JPRN-UMIN000046104	2013/03/01	21/11/2021	Research for the development of assessment strategy and treatment for cognitive impairment of Parkin ...	Neuroimaging study for the assessment and treatment of cognitive impairment of the patients with Par ...	Parkinson's disease	This study followed a randomized double-blind crossover design for the patients with mild cognitive ...	Nagoya City University	NULL	Complete: follow-up complete	60years-old	75years-old	Male and Female	12	Not applicable	Japan
6	NCT01108029 (ClinicalTrials.gov)	October 2009	20/7/2009	Study of Memantine for Gait Disorders And Attention Deficit In Parkinson's Disease	Study of Memantineto Treat Gait Disorders And Attention Deficit In Parkinson's Disease: A Randomized ...	Parkinson's Disease;Gait Disorders, Neurologic	Drug: memantine;Drug: placebo	University Hospital, Lille	NULL	Completed	30 Years	80 Years	Both	28	Phase 4	France
7	EUCTR2005-002038-36-GR (EUCTR)	27/02/2007	09/10/2006	A randomised, double-blind, placebo-controlled, 6-month study of the efficacy and safety of memantin ...	A randomised, double-blind, placebo-controlled, 6-month study of the efficacy and safety of memantin ...	Patients with Parkinson’s disease dementia or dementia with Lewy Bodies MedDRA version: 8.1;Level: L ...	Trade Name: Ebixa Product Name: Ebixa INN or Proposed INN: MEMANTINE HYDROCHLORIDE Trade Name: Ebixa Prod ...	H. Lundbeck A/S	NULL	Not Recruiting			Female: yes Male: yes	200	Phase 3	France;Greece;Spain;Austria;Germany;Italy;United Kingdom
8	NCT00855686 (ClinicalTrials.gov)	January 2007	3/3/2009	Memantine Versus Placebo in Parkinson's Disease Dementia or Dementia With Lewy Bodies	A Randomised, Double-blind, Placebo-controlled, 6-month Study of the Efficacy and Safety of Memantin ...	Parkinson's Disease Dementia;Dementia With Lewy Bodies	Drug: Memantine;Drug: Placebo	H. Lundbeck A/S	NULL	Completed	50 Years	N/A	Both	199	Phase 4	Germany
9	EUCTR2005-002038-36-FR (EUCTR)	01/12/2006	24/08/2010	A randomised, double-blind, placebo-controlled, 6-month study of the efficacy and safety of memantin ...	A randomised, double-blind, placebo-controlled, 6-month study of the efficacy and safety of memantin ...	Patients with Parkinson’s disease dementia or dementia with Lewy Bodies	Trade Name: Ebixa Product Name: Ebixa INN or Proposed INN: MEMANTINE HYDROCHLORIDE Trade Name: Ebixa Prod ...	H. Lundbeck A/S	NULL	Not Recruiting			Female: yes Male: yes	200	Phase 3	France;Greece;Spain;Austria;Germany;Italy;United Kingdom
10	EUCTR2005-002038-36-DE (EUCTR)	29/11/2006	19/01/2007	A randomised, double-blind, placebo-controlled, 6-month study of the efficacy and safety of memantin ...	A randomised, double-blind, placebo-controlled, 6-month study of the efficacy and safety of memantin ...	Patients with Parkinson’s disease dementia or dementia with Lewy Bodies	Trade Name: Ebixa Product Name: Memantine INN or Proposed INN: MEMANTINE HYDROCHLORIDE Product Name: Mem ...	H. Lundbeck A/S	NULL	Not Recruiting			Female: yes Male: yes	200		United Kingdom;Germany;France;Spain;Italy;Greece;Austria

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